ES2107776T3 - Procedimiento y dispositivo de inyeccion de un liquido esteril y apirogeno obtenido por filtracion. - Google Patents

Procedimiento y dispositivo de inyeccion de un liquido esteril y apirogeno obtenido por filtracion.

Info

Publication number
ES2107776T3
ES2107776T3 ES94420131T ES94420131T ES2107776T3 ES 2107776 T3 ES2107776 T3 ES 2107776T3 ES 94420131 T ES94420131 T ES 94420131T ES 94420131 T ES94420131 T ES 94420131T ES 2107776 T3 ES2107776 T3 ES 2107776T3
Authority
ES
Spain
Prior art keywords
liquid
injection
apirogen
filtration
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94420131T
Other languages
English (en)
Inventor
Laurent Simard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gambro Industries SAS
Original Assignee
Hospal Industrie SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hospal Industrie SAS filed Critical Hospal Industrie SAS
Application granted granted Critical
Publication of ES2107776T3 publication Critical patent/ES2107776T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D65/00Accessories or auxiliary operations, in general, for separation processes or apparatus using semi-permeable membranes
    • B01D65/10Testing of membranes or membrane apparatus; Detecting or repairing leaks
    • B01D65/102Detection of leaks in membranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654Dialysates therefor
    • A61M1/1656Apparatus for preparing dialysates
    • A61M1/1672Apparatus for preparing dialysates using membrane filters, e.g. for sterilising the dialysate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/342Adding solutions to the blood, e.g. substitution solutions
    • A61M1/3424Substitution fluid path
    • A61M1/3437Substitution fluid path downstream of the filter, e.g. post-dilution with filtrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/342Adding solutions to the blood, e.g. substitution solutions
    • A61M1/3455Substitution fluids
    • A61M1/3462Circuits for the preparation thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/342Adding solutions to the blood, e.g. substitution solutions
    • A61M1/3455Substitution fluids
    • A61M1/3465Substitution fluids using dialysate as substitution fluid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D65/00Accessories or auxiliary operations, in general, for separation processes or apparatus using semi-permeable membranes
    • B01D65/10Testing of membranes or membrane apparatus; Detecting or repairing leaks
    • B01D65/104Detection of leaks in membrane apparatus or modules
    • CCHEMISTRY; METALLURGY
    • C02TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02FTREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F1/00Treatment of water, waste water, or sewage
    • C02F1/44Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis
    • C02F1/444Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis by ultrafiltration or microfiltration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/17General characteristics of the apparatus with redundant control systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/70General characteristics of the apparatus with testing or calibration facilities
    • A61M2205/705Testing of filters for leaks
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/70General characteristics of the apparatus with testing or calibration facilities
    • A61M2205/707Testing of filters for clogging

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Hydrology & Water Resources (AREA)
  • Environmental & Geological Engineering (AREA)
  • Water Supply & Treatment (AREA)
  • Organic Chemistry (AREA)
  • External Artificial Organs (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)

Abstract

EL DISPOSITIVO DE INYECCION DE UN LIQUIDO ESTERIL Y APIROGENO COMPRENDE: UN PRIMER Y UN SEGUNDO COMPARTIMENTOS (16, 17) SEPARADOS POR UNA MEMBRANA POROSA (18), TENIENDO EL PRIMER COMPARTIMENTO (16) UNA ENTRADA CONECTABLE A UNA FUENTE (11) QUE TIENE UNA SALIDA CONECTADA A UNA CANALIZACION DE INYECCION (22). PARA HACER CIRCULAR EL LIQUIDO A TRAVES DEL FILTRO PRINCIPAL (15) Y EN LA CANALIZACION DE INYECCION (22), 27) DE VERIFICACION DE LA INTEGRIDAD DEL FILTRO PRINCIPAL QUE COMPRENDE: RIAS Y ELEMENTOS PYROGENOS DISPUESTO SOBRE LA CANALIZACION DE INYECCION (22), Y IAMIENTO DEL FILTRO SECUNDARIO (24) DURANTE LA INYECCION DE LIQUIDO. LA INVENCION ENCUENTRA UNA APLICACION PARTICULAR EN EL CASO EN QUE EL LIQUIDO INYECTADO ES LIQUIDO DE DIALISIS ESTERILIZADO EN LINEA PARA SER INYECTADO COMO LIQUIDO DE SUSTITUCION.
ES94420131T 1993-04-27 1994-04-27 Procedimiento y dispositivo de inyeccion de un liquido esteril y apirogeno obtenido por filtracion. Expired - Lifetime ES2107776T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9305198A FR2704432B1 (fr) 1993-04-27 1993-04-27 Dispositif d'injection de liquide dans un circuit extracorporel de sang.

Publications (1)

Publication Number Publication Date
ES2107776T3 true ES2107776T3 (es) 1997-12-01

Family

ID=9446658

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94420131T Expired - Lifetime ES2107776T3 (es) 1993-04-27 1994-04-27 Procedimiento y dispositivo de inyeccion de un liquido esteril y apirogeno obtenido por filtracion.

Country Status (10)

Country Link
US (1) US5476592A (es)
EP (1) EP0622087B1 (es)
JP (1) JP3553637B2 (es)
CN (1) CN1117588C (es)
AT (1) ATE157015T1 (es)
CA (1) CA2122207C (es)
DE (1) DE69405038T2 (es)
ES (1) ES2107776T3 (es)
FR (1) FR2704432B1 (es)
WO (1) WO1994025085A1 (es)

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FR2723002B1 (fr) * 1994-07-26 1996-09-06 Hospal Ind Dispositif et procede pour preparer un liquide de traitement par filtration
DE19607162C2 (de) * 1996-02-26 1998-01-15 Fresenius Ag Verwendung eines Dialysators mit zwei Modulen zur Durchführung eines Verfahrens zum Filtrieren und sofortigen Verwenden von Substituatflüssigkeit in einer Hämodialfiltrationsvorrichtung
DE19700466A1 (de) * 1997-01-09 1998-07-16 Polaschegg Hans Dietrich Dr Einrichtung und Verfahren zur Hämodiafiltration
WO2001037899A2 (en) * 1997-02-14 2001-05-31 Nxstage Medical, Inc. Extracorporeal circuits for performing hemofiltration employing pressure sensing without an air interface
US6852090B2 (en) 1997-02-14 2005-02-08 Nxstage Medical, Inc. Fluid processing systems and methods using extracorporeal fluid flow panels oriented within a cartridge
ES2324506T3 (es) * 1998-07-31 2009-08-07 Nephros, Inc. Dispositivo para hemodiafiltracion eficaz.
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FR2791574B1 (fr) * 1999-03-30 2002-06-14 Hospal Ind Procede et dispositif pour steriliser et dispenser un liquide a usage medical
KR20020010132A (ko) * 1999-03-30 2002-02-02 아스케토르프 괴단 열에 민감한 유체의 살균 방법 및 장치
FR2791575B1 (fr) * 1999-03-30 2002-06-28 Hospal Ind Procede et dispositif pour steriliser et dispenser un liquide a usage medical
FR2791576B1 (fr) * 1999-03-30 2002-06-14 Hospal Ind Procede et dispositif pour steriliser et dispenser un liquide a usage medical
US6579494B1 (en) 1999-03-30 2003-06-17 Hospal Industrie Process and device for sterilizing and dispensing a liquid for medical use
US6406631B1 (en) 1999-07-30 2002-06-18 Nephros, Inc. Two stage diafiltration method and apparatus
CA2381557C (en) * 1999-08-12 2006-05-09 Kvaerner Process Systems A.S. Protection system to prevent damage to a gas diffusion membrane
US6635026B1 (en) 1999-11-08 2003-10-21 Hospal Industrie Haemofiltration machine for independently controlling the concentration of a least two ionic substances in a patient's internal medium
FR2800618B1 (fr) 1999-11-08 2002-02-22 Bert Christophe Appareil d'hemofiltration permettant de controler, de facon independante, la concentration d'au moins deux substances ioniques dans le milieu interieur d'un patient
US7780619B2 (en) 1999-11-29 2010-08-24 Nxstage Medical, Inc. Blood treatment apparatus
US7347849B2 (en) * 2001-05-24 2008-03-25 Nxstage Medical, Inc. Modular medical treatment replaceable component
US6635179B1 (en) 1999-12-30 2003-10-21 Nephros, Inc. Sterile fluid filtration cartridge and method for using same
CA2396853A1 (en) 2000-01-11 2001-07-19 Nephros, Inc. Thermally enhanced dialysis/diafiltration system
DE60141350D1 (de) 2000-10-30 2010-04-01 Nephros Inc Zweistufige filterpatrone
CN100346869C (zh) * 2001-02-07 2007-11-07 尼弗茹斯公司 用于血液透析过滤供应组件的方法和装置
US6649063B2 (en) 2001-07-12 2003-11-18 Nxstage Medical, Inc. Method for performing renal replacement therapy including producing sterile replacement fluid in a renal replacement therapy unit
US7112273B2 (en) * 2002-09-27 2006-09-26 Nxstage Medical, Inc. Volumetric fluid balance control for extracorporeal blood treatment
US8235931B2 (en) 2003-01-15 2012-08-07 Nxstage Medical, Inc. Waste balancing for extracorporeal blood treatment systems
US7686778B2 (en) * 2003-01-15 2010-03-30 Nxstage Medical, Inc. Waste balancing for extracorporeal blood treatment systems
CN101232910B (zh) * 2005-07-01 2011-12-14 甘布罗伦迪亚股份公司 一种测试过滤器的装置
US7534349B2 (en) * 2005-09-02 2009-05-19 Nephros, Inc. Dual stage ultrafilter devices in the form of portable filter devices, shower devices, and hydration packs
US7775375B2 (en) 2005-11-03 2010-08-17 Medica S.R.L. Redundant ultrafiltration device
DE102006012198A1 (de) * 2006-03-16 2007-09-27 Seccua Gmbh Steuerungen eines Filtrationssystems
US20070243113A1 (en) * 2006-04-12 2007-10-18 Dileo Anthony Filter with memory, communication and concentration sensor
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JP5399218B2 (ja) * 2009-11-24 2014-01-29 日機装株式会社 血液浄化装置
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EP2519277B1 (en) * 2009-12-28 2017-09-27 Gambro Lundia AB Apparatus and method for prediction of rapid symptomatic blood pressure decrease
DE102010048771A1 (de) * 2010-10-14 2012-05-16 B. Braun Avitum Ag Verfahren und Vorrichtung zur Messung und Behebung von Systemänderungen in einer Vorrichtung zur Behandlung von Blut
ES2550798T3 (es) * 2010-11-10 2015-11-12 Gambro Lundia Ab Dispositivo para el tratamiento de sangre con extracción selectiva de solutos
EP2962710A1 (de) * 2014-07-03 2016-01-06 Berlin Heart GmbH Verfahren und Herzunterstützungssystem zur Bestimmung eines Auslassdrucks
JP6388118B2 (ja) 2014-09-19 2018-09-12 澁谷工業株式会社 人工透析装置
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CN111088156B (zh) * 2020-01-06 2021-03-30 山东省海洋资源与环境研究院 一种用于海洋环境监测的大肠菌群测试片及与其配合使用的附属装置
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JP2023049603A (ja) * 2021-09-29 2023-04-10 旭化成メディカル株式会社 濾過器の試験方法及び製造方法

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Also Published As

Publication number Publication date
FR2704432A1 (fr) 1994-11-04
JPH078553A (ja) 1995-01-13
EP0622087A1 (fr) 1994-11-02
DE69405038T2 (de) 1998-02-26
CN1108028A (zh) 1995-09-06
ATE157015T1 (de) 1997-09-15
FR2704432B1 (fr) 1995-06-23
US5476592A (en) 1995-12-19
WO1994025085A1 (fr) 1994-11-10
JP3553637B2 (ja) 2004-08-11
CN1117588C (zh) 2003-08-13
EP0622087B1 (fr) 1997-08-20
CA2122207C (fr) 2007-04-03
DE69405038D1 (de) 1997-09-25
CA2122207A1 (fr) 1994-10-28

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