ES2109512T3 - Macrolactama (ciclamenol) antiinflamatoria. - Google Patents

Macrolactama (ciclamenol) antiinflamatoria.

Info

Publication number
ES2109512T3
ES2109512T3 ES93919327T ES93919327T ES2109512T3 ES 2109512 T3 ES2109512 T3 ES 2109512T3 ES 93919327 T ES93919327 T ES 93919327T ES 93919327 T ES93919327 T ES 93919327T ES 2109512 T3 ES2109512 T3 ES 2109512T3
Authority
ES
Spain
Prior art keywords
pct
cyclamenol
sec
macrolactam
inflammatory
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93919327T
Other languages
English (en)
Inventor
Hartwig Muller
Erwin Bischoff
Volker-Bernd Fiedler
Karlheinz Weber
Burkhard Fugmann
Bruno Rosen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of ES2109512T3 publication Critical patent/ES2109512T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
    • C07D225/02—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

LA INVENCION SE REFIERE AL CICLAMENOL DE SUSTANCIA NATURAL CON LA FORMULA (IA), UN PROCESO PARA SU ELABORACION A PARTIR DE MICROORGANISMOS DEL ORDEN DE LOS AMINOCETALES, EN PARTICULAR A PARTIR DEL TRONCO ESTREPTOMICES MHW 846, SUS DERIVADOS QUIMICOS ASI COMO SU UTILIZACION COMO MEDICAMENTO, EN PARTICULAR PARA ENFERMEDADES INFLAMATORIAS AGUADOS O CRONICAS EN EL CAMPO DE LA MEDICINA Y EN VETERINARIA.
ES93919327T 1992-09-18 1993-09-13 Macrolactama (ciclamenol) antiinflamatoria. Expired - Lifetime ES2109512T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4231289A DE4231289A1 (de) 1992-09-18 1992-09-18 Neuer Naturstoff Cyclamenol und chemische Derivate

Publications (1)

Publication Number Publication Date
ES2109512T3 true ES2109512T3 (es) 1998-01-16

Family

ID=6468283

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93919327T Expired - Lifetime ES2109512T3 (es) 1992-09-18 1993-09-13 Macrolactama (ciclamenol) antiinflamatoria.

Country Status (10)

Country Link
US (1) US5565561A (es)
EP (1) EP0660825B1 (es)
JP (1) JPH08501687A (es)
AT (1) ATE160772T1 (es)
CA (1) CA2144747A1 (es)
DE (2) DE4231289A1 (es)
DK (1) DK0660825T3 (es)
ES (1) ES2109512T3 (es)
GR (1) GR3025682T3 (es)
WO (1) WO1994006774A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7112581B2 (en) * 2002-09-27 2006-09-26 Nereus Pharmaceuticals, Inc. Macrocyclic lactams
US8097709B2 (en) * 2007-08-22 2012-01-17 Novobiotic Pharmaceuticals, Inc. Macrolactam compounds
CN116199702B (zh) * 2021-12-01 2026-01-09 上海交通大学医学院附属仁济医院 一种大环内酰胺类化合物、其制备方法及应用
CN115584329B (zh) * 2022-07-11 2026-03-13 湖北省生物农药工程研究中心 一株链霉菌、其代谢产物及其应用

Also Published As

Publication number Publication date
WO1994006774A1 (de) 1994-03-31
DE59307796D1 (de) 1998-01-15
EP0660825A1 (de) 1995-07-05
EP0660825B1 (de) 1997-12-03
JPH08501687A (ja) 1996-02-27
DK0660825T3 (da) 1998-08-10
ATE160772T1 (de) 1997-12-15
US5565561A (en) 1996-10-15
CA2144747A1 (en) 1994-03-31
DE4231289A1 (de) 1994-03-24
GR3025682T3 (en) 1998-03-31

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