ES2111168T3 - Comprimidos de liberacion sostenida que contienen bupropion. - Google Patents
Comprimidos de liberacion sostenida que contienen bupropion.Info
- Publication number
- ES2111168T3 ES2111168T3 ES93918020T ES93918020T ES2111168T3 ES 2111168 T3 ES2111168 T3 ES 2111168T3 ES 93918020 T ES93918020 T ES 93918020T ES 93918020 T ES93918020 T ES 93918020T ES 2111168 T3 ES2111168 T3 ES 2111168T3
- Authority
- ES
- Spain
- Prior art keywords
- sustained release
- tablets containing
- release tablets
- hydrochloride
- containing bupropion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000007939 sustained release tablet Substances 0.000 title abstract 2
- SNPPWIUOZRMYNY-UHFFFAOYSA-N bupropion Chemical compound CC(C)(C)NC(C)C(=O)C1=CC=CC(Cl)=C1 SNPPWIUOZRMYNY-UHFFFAOYSA-N 0.000 title 1
- 229960001058 bupropion Drugs 0.000 title 1
- IKBZAUYPBWFMDI-UHFFFAOYSA-N 5-bromo-4-methoxy-7-methyl-2,3-dihydro-1h-indene Chemical compound C1=C(Br)C(OC)=C2CCCC2=C1C IKBZAUYPBWFMDI-UHFFFAOYSA-N 0.000 abstract 2
- 229960004367 bupropion hydrochloride Drugs 0.000 abstract 2
- QIJRTFXNRTXDIP-UHFFFAOYSA-N (1-carboxy-2-sulfanylethyl)azanium;chloride;hydrate Chemical compound O.Cl.SCC(N)C(O)=O QIJRTFXNRTXDIP-UHFFFAOYSA-N 0.000 abstract 1
- IVLXQGJVBGMLRR-UHFFFAOYSA-N 2-aminoacetic acid;hydron;chloride Chemical compound Cl.NCC(O)=O IVLXQGJVBGMLRR-UHFFFAOYSA-N 0.000 abstract 1
- 229960001305 cysteine hydrochloride Drugs 0.000 abstract 1
- 229960001269 glycine hydrochloride Drugs 0.000 abstract 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- General Preparation And Processing Of Foods (AREA)
Abstract
UNA TABLETA DE SUMINISTRO CONTROLADO CONTINUO QUE TIENE AL MENOS UN AÑO DE VIDA UTIL Y QUE CONTIENE HIDROCLORURO DE BUPROPION, METILCELULOSA DE HIDROXIPROPILO E HIDROCLORURO DE CISTEINA O HIDROCLORURO DE GLICINA, CON UNA TABLETA QUE TIENE UNA RELACION DE AREA SUPERFICIAL A VOLUMEN EFECTIVA PARA CONTROLAR LA LIBERACION DEL HIDROCLORURO DE BUPROPION EN EL CUERPO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929217295A GB9217295D0 (en) | 1992-08-14 | 1992-08-14 | Controlled released tablets |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2111168T3 true ES2111168T3 (es) | 1998-03-01 |
Family
ID=10720358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES93918020T Expired - Lifetime ES2111168T3 (es) | 1992-08-14 | 1993-08-13 | Comprimidos de liberacion sostenida que contienen bupropion. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5427798A (es) |
| EP (1) | EP0656775B1 (es) |
| JP (1) | JPH08500110A (es) |
| KR (1) | KR100294154B1 (es) |
| AT (1) | ATE161422T1 (es) |
| AU (1) | AU677595B2 (es) |
| CA (1) | CA2142320C (es) |
| CY (1) | CY2143B1 (es) |
| DE (1) | DE69316015T2 (es) |
| ES (1) | ES2111168T3 (es) |
| GB (1) | GB9217295D0 (es) |
| GR (1) | GR3025794T3 (es) |
| IL (1) | IL106693A (es) |
| LU (1) | LU90656I2 (es) |
| MX (1) | MX9304967A (es) |
| NZ (1) | NZ254947A (es) |
| SG (1) | SG43911A1 (es) |
| TW (1) | TW260607B (es) |
| WO (1) | WO1994004138A1 (es) |
| ZA (1) | ZA935942B (es) |
Families Citing this family (236)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9315856D0 (en) * | 1993-07-30 | 1993-09-15 | Wellcome Found | Stabilized pharmaceutical |
| US5541231A (en) * | 1993-07-30 | 1996-07-30 | Glaxo Wellcome Inc. | Stabilized Pharmaceutical |
| US5616344A (en) * | 1994-06-14 | 1997-04-01 | Fuisz Technologies Ltd. | Apparatus and process for strengthening low density compression dosage units and product therefrom |
| BR9812553B1 (pt) * | 1997-09-25 | 2010-06-01 | formulação medicamentosa em pélete de difusão controlada e em um sistema matriz. | |
| US6221917B1 (en) | 1997-12-30 | 2001-04-24 | American Home Products Corporation | Pharmaceutical composition containing bupropion hydrochloride and a stabilizer |
| US5968553A (en) * | 1997-12-30 | 1999-10-19 | American Home Products Corporation | Pharmaceutical composition containing bupropion hydrochloride and an inorganic acid stabilizer |
| US7098206B2 (en) * | 1998-01-21 | 2006-08-29 | Smithkline Beecham Corporation | Pharmaceutically active morpholinol |
| US6998400B2 (en) * | 1998-01-22 | 2006-02-14 | Smithkline Beecham Corporation | Pharmaceutically active morpholinol |
| AU2483599A (en) | 1998-01-29 | 1999-08-16 | Sepracor, Inc. | Pharmaceutical uses of optically pure (-)-bupropion |
| WO1999038499A2 (en) * | 1998-01-29 | 1999-08-05 | Sepracor Inc. | Methods and compositions for aiding in smoking cessation and for treating pain and other disorders using optically pure (-)-bupropion |
| WO1999038503A1 (en) * | 1998-01-29 | 1999-08-05 | Sepracor Inc. | Pharmacological uses of optically pure (+)-bupropion |
| WO1999038502A1 (en) * | 1998-01-29 | 1999-08-05 | Sepracor Inc. | Pharmaceutical uses of optically pure (+)-bupropion |
| US6150420A (en) * | 1998-06-01 | 2000-11-21 | Theramax, Inc. | Method for enhanced brain delivery of bupropion |
| US6153223A (en) * | 1998-06-05 | 2000-11-28 | Watson Pharmaceuticals, Inc. | Stabilized pharmaceutical compositions |
| US6033686A (en) * | 1998-10-30 | 2000-03-07 | Pharma Pass Llc | Controlled release tablet of bupropion hydrochloride |
| US6096341A (en) * | 1998-10-30 | 2000-08-01 | Pharma Pass Llc | Delayed release tablet of bupropion hydrochloride |
| US6238697B1 (en) * | 1998-12-21 | 2001-05-29 | Pharmalogix, Inc. | Methods and formulations for making bupropion hydrochloride tablets using direct compression |
| US6855820B2 (en) * | 1999-01-20 | 2005-02-15 | Smithkline Beecham Corporation | Pharmaceutically active morpholinol |
| US6734213B2 (en) | 1999-01-20 | 2004-05-11 | Smithkline Beecham Corporation | Pharmaceutically active morpholinol |
| US8545880B2 (en) * | 1999-02-26 | 2013-10-01 | Andrx Pharmaceuticals, Llc | Controlled release oral dosage form |
| US6210716B1 (en) * | 1999-02-26 | 2001-04-03 | Andrx Pharmaceuticals, Inc. | Controlled release bupropion formulation |
| US6589553B2 (en) * | 2001-02-08 | 2003-07-08 | Andrx Pharmaceuticals, Inc. | Controlled release oral dosage form |
| US6337328B1 (en) * | 1999-03-01 | 2002-01-08 | Sepracor, Inc. | Bupropion metabolites and methods of use |
| US6342496B1 (en) * | 1999-03-01 | 2002-01-29 | Sepracor Inc. | Bupropion metabolites and methods of use |
| USD430285S (en) * | 1999-04-16 | 2000-08-29 | Merck & Co., Inc. | Tablet |
| US6280763B1 (en) | 1999-05-10 | 2001-08-28 | Pierce Management, Llc | Apparatus and method for transdermal delivery of bupropion |
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| US6306436B1 (en) | 2000-04-28 | 2001-10-23 | Teva Pharmaceuticals Usa, Inc. | Stabilized, acid-free formulation for sustained release of bupropion hydrochloride |
| EP1357898A4 (en) * | 2001-02-08 | 2005-07-13 | Andrx Pharmaceuticals Inc | ORAL DOSAGE FORM WITH ENHANCED REGULATED RELEASE |
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| DE3485618D1 (de) * | 1984-08-17 | 1992-04-30 | Wellcome Found | Zusammensetzung zur kontrollierten abgabe eines wirkstoffes und ihre herstellung. |
| HUT69390A (en) * | 1991-05-07 | 1995-09-28 | Dynagen Inc | Controlled, sustained release delivery system for smoking cessation |
-
1992
- 1992-08-14 GB GB929217295A patent/GB9217295D0/en active Pending
-
1993
- 1993-08-12 US US08/105,447 patent/US5427798A/en not_active Expired - Lifetime
- 1993-08-13 ZA ZA935942A patent/ZA935942B/xx unknown
- 1993-08-13 AT AT93918020T patent/ATE161422T1/de active
- 1993-08-13 SG SG1996005086A patent/SG43911A1/en unknown
- 1993-08-13 IL IL106693A patent/IL106693A/xx not_active IP Right Cessation
- 1993-08-13 NZ NZ254947A patent/NZ254947A/en not_active IP Right Cessation
- 1993-08-13 ES ES93918020T patent/ES2111168T3/es not_active Expired - Lifetime
- 1993-08-13 TW TW082106498A patent/TW260607B/zh not_active IP Right Cessation
- 1993-08-13 DE DE69316015T patent/DE69316015T2/de not_active Expired - Lifetime
- 1993-08-13 JP JP6506019A patent/JPH08500110A/ja active Pending
- 1993-08-13 WO PCT/GB1993/001722 patent/WO1994004138A1/en not_active Ceased
- 1993-08-13 AU AU47258/93A patent/AU677595B2/en not_active Expired
- 1993-08-13 KR KR1019950700497A patent/KR100294154B1/ko not_active Expired - Lifetime
- 1993-08-13 EP EP93918020A patent/EP0656775B1/en not_active Expired - Lifetime
- 1993-08-13 CA CA002142320A patent/CA2142320C/en not_active Expired - Lifetime
- 1993-08-16 MX MX9304967A patent/MX9304967A/es unknown
-
1997
- 1997-12-30 GR GR970403389T patent/GR3025794T3/el unknown
-
1999
- 1999-11-29 CY CY9900040A patent/CY2143B1/xx unknown
-
2000
- 2000-10-18 LU LU90656C patent/LU90656I2/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR100294154B1 (ko) | 2001-09-17 |
| IL106693A (en) | 1997-06-10 |
| KR950702827A (ko) | 1995-08-23 |
| DE69316015D1 (de) | 1998-02-05 |
| SG43911A1 (en) | 1997-11-14 |
| EP0656775A1 (en) | 1995-06-14 |
| ZA935942B (en) | 1995-02-13 |
| CA2142320C (en) | 2001-10-09 |
| HK1004323A1 (en) | 1998-11-20 |
| AU677595B2 (en) | 1997-05-01 |
| US5427798A (en) | 1995-06-27 |
| AU4725893A (en) | 1994-03-15 |
| JPH08500110A (ja) | 1996-01-09 |
| ATE161422T1 (de) | 1998-01-15 |
| EP0656775B1 (en) | 1997-12-29 |
| TW260607B (es) | 1995-10-21 |
| LU90656I2 (fr) | 2001-01-15 |
| IL106693A0 (en) | 1993-12-08 |
| CA2142320A1 (en) | 1994-03-03 |
| GB9217295D0 (en) | 1992-09-30 |
| MX9304967A (es) | 1994-05-31 |
| DE69316015T2 (de) | 1998-04-16 |
| CY2143B1 (en) | 2002-06-21 |
| NZ254947A (en) | 1996-04-26 |
| GR3025794T3 (en) | 1998-03-31 |
| WO1994004138A1 (en) | 1994-03-03 |
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