ES2112042T3 - Procedimiento para la recuperacion de natamicina. - Google Patents
Procedimiento para la recuperacion de natamicina.Info
- Publication number
- ES2112042T3 ES2112042T3 ES95905216T ES95905216T ES2112042T3 ES 2112042 T3 ES2112042 T3 ES 2112042T3 ES 95905216 T ES95905216 T ES 95905216T ES 95905216 T ES95905216 T ES 95905216T ES 2112042 T3 ES2112042 T3 ES 2112042T3
- Authority
- ES
- Spain
- Prior art keywords
- natamycin
- broth
- recovery
- procedure
- followed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- NCXMLFZGDNKEPB-FFPOYIOWSA-N natamycin Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/C[C@@H](C)OC(=O)/C=C/[C@H]2O[C@@H]2C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 NCXMLFZGDNKEPB-FFPOYIOWSA-N 0.000 title abstract 6
- 229960003255 natamycin Drugs 0.000 title abstract 6
- 235000010298 natamycin Nutrition 0.000 title abstract 6
- 239000004311 natamycin Substances 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 2
- 238000011084 recovery Methods 0.000 title 1
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 2
- 238000000855 fermentation Methods 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Abstract
UN NUEVO PROCESO PARA LA RECUPERACION DE NATAMICINA DE ALTA PUREZA A PARTIR DE CALDO DE FERMENTACION QUE CONTIENE NATAMICINA, SE COMPONE DE LOS PASOS DE AJUSTAR EL PH DEL CALDO POR ENCIMA DE ALREDEDOR DE 10 Y AÑADIR UNA CANTIDAD DE UN SOLVENTE HIDROMISCIBLE, COMO EL ISOPROPANOL, SUFICIENTE PARA DISOLVER LA NATAMICINA EN EL CALDO, Y A CONTINUACION ELIMINAR LOS SOLIDOS INSOLUBLES DEL CALDO DE PH-AJUSTADO, Y DESPUES REDUCIR EL PH DEL CALDO A UN NIVEL SUFICIENTE PARA PRECIPITAR LA NATAMICINA Y ELIMINAR LA NATAMICINA DEL CALDO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22196094A | 1994-03-31 | 1994-03-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2112042T3 true ES2112042T3 (es) | 1998-03-16 |
Family
ID=22830169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES95905216T Expired - Lifetime ES2112042T3 (es) | 1994-03-31 | 1995-01-19 | Procedimiento para la recuperacion de natamicina. |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0754239B1 (es) |
| JP (1) | JP2750222B2 (es) |
| AT (1) | ATE159051T1 (es) |
| AU (1) | AU677890B2 (es) |
| CA (1) | CA2186259C (es) |
| DE (1) | DE69500846T2 (es) |
| DK (1) | DK0754239T3 (es) |
| ES (1) | ES2112042T3 (es) |
| GR (1) | GR3025755T3 (es) |
| MX (1) | MX9604372A (es) |
| WO (1) | WO1995027073A1 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0251582A (ja) * | 1988-08-12 | 1990-02-21 | Kyokado Eng Co Ltd | 地盤注入用薬液 |
| US6150143A (en) * | 1996-02-09 | 2000-11-21 | Gist-Brocades B.V. | Natamycin recovery |
| AU704161B2 (en) * | 1996-02-09 | 1999-04-15 | Gist-Brocades B.V. | Natamycin recovery |
| JP3737801B2 (ja) * | 2000-10-05 | 2006-01-25 | テバ ジョジセルジャール レースベニュタールシャシャーグ | プラバスタチンラクトン及びエピプラバスタチンを実質的に含まないプラバスタチンナトリウム、並びにそれを含む組成物 |
| EP1641343A1 (en) | 2003-06-02 | 2006-04-05 | DSM IP Assets B.V. | Stable aqueous solution of natamycin fungicide |
| DK1846566T3 (da) | 2004-10-28 | 2013-07-01 | Dsm Ip Assets Bv | Stabile nåleformede krystaller af natamycin |
| CN100393738C (zh) * | 2005-07-05 | 2008-06-11 | 广州市微生物研究所 | 纳他霉素的提取纯化方法 |
| DK2260706T3 (en) | 2005-10-04 | 2016-08-22 | Dsm Ip Assets Bv | Enhanced antifungal composition |
| CN112512334A (zh) * | 2018-07-11 | 2021-03-16 | 朗盛德国有限责任公司 | 食品与饮料的消毒和防腐方法 |
| CN117587087A (zh) * | 2023-11-22 | 2024-02-23 | 浙江新银象生物工程有限公司 | 一种液体纳他霉素的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3892850A (en) * | 1956-03-13 | 1975-07-01 | Gist Brocades Nv | Pimaricin and process of producing same |
| JPS63117952A (ja) * | 1986-11-07 | 1988-05-21 | 呉羽化学工業株式会社 | 高靭性コランダム−ルチル複合焼結体およびその製造方法 |
| CA2097840C (en) * | 1990-12-07 | 2002-02-05 | James R. Millis | Natamycin recovery |
-
1995
- 1995-01-19 ES ES95905216T patent/ES2112042T3/es not_active Expired - Lifetime
- 1995-01-19 EP EP95905216A patent/EP0754239B1/en not_active Expired - Lifetime
- 1995-01-19 CA CA002186259A patent/CA2186259C/en not_active Expired - Lifetime
- 1995-01-19 WO PCT/IB1995/000040 patent/WO1995027073A1/en not_active Ceased
- 1995-01-19 DK DK95905216.8T patent/DK0754239T3/da active
- 1995-01-19 AT AT95905216T patent/ATE159051T1/de active
- 1995-01-19 DE DE69500846T patent/DE69500846T2/de not_active Expired - Lifetime
- 1995-01-19 JP JP7525534A patent/JP2750222B2/ja not_active Expired - Lifetime
- 1995-01-19 MX MX9604372A patent/MX9604372A/es unknown
- 1995-01-19 AU AU13911/95A patent/AU677890B2/en not_active Expired
-
1997
- 1997-12-23 GR GR970403405T patent/GR3025755T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX9604372A (es) | 1997-06-28 |
| AU677890B2 (en) | 1997-05-08 |
| CA2186259C (en) | 1999-12-14 |
| WO1995027073A1 (en) | 1995-10-12 |
| DE69500846D1 (de) | 1997-11-13 |
| EP0754239A1 (en) | 1997-01-22 |
| GR3025755T3 (en) | 1998-03-31 |
| JP2750222B2 (ja) | 1998-05-13 |
| JPH09504960A (ja) | 1997-05-20 |
| ATE159051T1 (de) | 1997-10-15 |
| EP0754239B1 (en) | 1997-10-08 |
| CA2186259A1 (en) | 1995-10-12 |
| AU1391195A (en) | 1995-10-23 |
| DE69500846T2 (de) | 1998-04-23 |
| DK0754239T3 (da) | 1998-05-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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