ES2114855T3 - Procedimiento para la preparacion de 2-acilamino-6-halogeno-purina a partir de 2,9-diacilguanina. - Google Patents

Procedimiento para la preparacion de 2-acilamino-6-halogeno-purina a partir de 2,9-diacilguanina.

Info

Publication number
ES2114855T3
ES2114855T3 ES90123794T ES90123794T ES2114855T3 ES 2114855 T3 ES2114855 T3 ES 2114855T3 ES 90123794 T ES90123794 T ES 90123794T ES 90123794 T ES90123794 T ES 90123794T ES 2114855 T3 ES2114855 T3 ES 2114855T3
Authority
ES
Spain
Prior art keywords
purine
diacilguanine
acilamino
halogen
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90123794T
Other languages
English (en)
Inventor
Winfried Dr Hertzsch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2114855T3 publication Critical patent/ES2114855T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

LA INVENCION SE REFIERE A UN PROCEDIMIENTO: QUE SE UTILIZA PARA PRODUCIR EL 2-ACILAMINO-6-HALOGENO-PURINA A PARTIR DEL 2,9-DIACILOGUANINA Y CONSISTE EN HALOGENAR EL 2,9-DIACILOGUANINA CON OXICLORURO DE FOSFORO U OXIBROMURO DE FOSFORO, EN PRESENCIA DE UNA BASE Y UNA SAL E HIDROLIZAR EL COMPUESTO RESULTANTE DE LA REACCION DE HALOGENACION.
ES90123794T 1989-12-16 1990-12-11 Procedimiento para la preparacion de 2-acilamino-6-halogeno-purina a partir de 2,9-diacilguanina. Expired - Lifetime ES2114855T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3941657A DE3941657A1 (de) 1989-12-16 1989-12-16 Verfahren zur herstellung von 2-acylamino-6-halogen-purin aus 2,9-diacylguanin

Publications (1)

Publication Number Publication Date
ES2114855T3 true ES2114855T3 (es) 1998-06-16

Family

ID=6395642

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90123794T Expired - Lifetime ES2114855T3 (es) 1989-12-16 1990-12-11 Procedimiento para la preparacion de 2-acilamino-6-halogeno-purina a partir de 2,9-diacilguanina.

Country Status (10)

Country Link
US (1) US5434263A (es)
EP (1) EP0433846B1 (es)
JP (1) JPH04234883A (es)
AT (1) ATE164160T1 (es)
DE (2) DE3941657A1 (es)
DK (1) DK0433846T3 (es)
ES (1) ES2114855T3 (es)
GR (1) GR3026624T3 (es)
IE (1) IE904518A1 (es)
PT (1) PT96211B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9102127D0 (en) * 1991-01-31 1991-03-13 Smithkline Beecham Plc Pharmaceuticals
CA2076886C (en) * 1991-11-22 2002-06-11 Masami Igi Method for production of 2-amino-6-halogenopurine and synthesis intermediate therefor
GB9201961D0 (en) 1992-01-30 1992-03-18 Smithkline Beecham Plc Pharmaceuticals
DE4231036A1 (de) * 1992-09-17 1994-03-24 Basf Ag Verfahren zur Herstellung von 2-Amino-6-halogenpurinen
JPH07133276A (ja) * 1993-09-17 1995-05-23 Jiyuuzen Kagaku Kk ２−アセチルアミノ−６−クロロプリンの製造方法
DE4415196C1 (de) * 1994-04-30 1995-04-27 Boehringer Ingelheim Kg Verbessertes Verfahren zur Herstellung von 2-Amino-6-chlorpurin und 2-Acylamino-6-chlorpurinen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405781A (en) * 1981-03-02 1983-09-20 Polaroid Corporation Method for preparing salts of 6-chloropurine
GB8507606D0 (en) * 1985-03-23 1985-05-01 Beecham Group Plc Process

Also Published As

Publication number Publication date
PT96211B (pt) 1998-05-29
EP0433846A1 (de) 1991-06-26
GR3026624T3 (en) 1998-07-31
DK0433846T3 (da) 1998-12-07
ATE164160T1 (de) 1998-04-15
DE59010812D1 (de) 1998-04-23
EP0433846B1 (de) 1998-03-18
PT96211A (pt) 1991-09-30
US5434263A (en) 1995-07-18
DE3941657A1 (de) 1991-06-20
JPH04234883A (ja) 1992-08-24
IE904518A1 (en) 1991-06-19

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