ES2118109T3 - Antigenos polisacaridos de streptococcus pneumoniae. - Google Patents

Antigenos polisacaridos de streptococcus pneumoniae.

Info

Publication number
ES2118109T3
ES2118109T3 ES92300654T ES92300654T ES2118109T3 ES 2118109 T3 ES2118109 T3 ES 2118109T3 ES 92300654 T ES92300654 T ES 92300654T ES 92300654 T ES92300654 T ES 92300654T ES 2118109 T3 ES2118109 T3 ES 2118109T3
Authority
ES
Spain
Prior art keywords
new
streptococcus pneumoniae
specific type
vaccines
polysaccharid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92300654T
Other languages
English (en)
Inventor
Peter J Kniskern
Charlotte C Ip
Arpi Hagopian
Jr John P Hennessey
William J Miller
Dennis J Kubek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27094962&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2118109(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of ES2118109T3 publication Critical patent/ES2118109T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/04Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6068Other bacterial proteins, e.g. OMP
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

LAS PREPARACIONES DE POLISACARIDOS CAPSULARES DE TIPO ESPECIFICO DEL STREPTOCOCCUS PNEUMONIAE QUE TIENEN COMO TERMINO MEDIO MENOS DE 1000 UNIDADES REPETIDAS DE OLIGOSACARIDOS APROXIMADAMENTE POR MOLECULA, POLIDISPERSIBILIDADES ENTRE 1.0 Y 1.4, VISCOSIDADES INTRINSECAS ENTRE 0.6 Y 3.0 DL/G Y UNA CONTAMINACION MENOR DEL 3% DE POLISACARIDOS DE TIPO ESPECIFICO POR POLISACARIDO C DE GRUPO ESPECIFICO, SE PREPARAN MEDIANTE UN NUEVO PROCESO. LOS NUEVOS PRODUCTOS DE POLISACARIDOS DE TIPO ESPECIFICO SON UTILES PARA LA PREPARACION DE VACUNAS, ESPECIALMENTE DE CONJUGADOS COVALENTES QUE CONTIENEN EL NUEVO POLISACARIDO ENLAZADO A UNA PROTEINA PORTADORA ESTIMULATORIA DE LA CELULA T. LAS VACUNAS QUE CONTIENEN LOS NUEVOS POLISACARIDOS SON UTILES PARA LA PREVENCION DE INFECCIONES Y DE ENFERMEDADES ASOCIADAS CON LA INFECCION POR EL STREPTOCOCCUS PNEUMONIAE.
ES92300654T 1991-01-28 1992-01-27 Antigenos polisacaridos de streptococcus pneumoniae. Expired - Lifetime ES2118109T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64657391A 1991-01-28 1991-01-28
US80794191A 1991-12-19 1991-12-19

Publications (1)

Publication Number Publication Date
ES2118109T3 true ES2118109T3 (es) 1998-09-16

Family

ID=27094962

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92300654T Expired - Lifetime ES2118109T3 (es) 1991-01-28 1992-01-27 Antigenos polisacaridos de streptococcus pneumoniae.

Country Status (9)

Country Link
US (1) US5847112A (es)
EP (1) EP0497524B1 (es)
JP (1) JP2904633B2 (es)
AT (1) ATE168270T1 (es)
CA (1) CA2059693C (es)
DE (1) DE69226211T2 (es)
DK (1) DK0497524T3 (es)
ES (1) ES2118109T3 (es)
IE (1) IE920221A1 (es)

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EP0497524B1 (en) 1998-07-15
DK0497524T3 (da) 1998-10-26
DE69226211T2 (de) 1999-03-18
US5847112A (en) 1998-12-08
DE69226211D1 (de) 1998-08-20
EP0497524A2 (en) 1992-08-05
JPH05148157A (ja) 1993-06-15
CA2059693A1 (en) 1992-07-29
JP2904633B2 (ja) 1999-06-14
EP0497524A3 (en) 1993-03-10
ATE168270T1 (de) 1998-08-15
IE920221A1 (en) 1992-07-29

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