ES2121365T3 - Sistema de electrodo catodico de iontoforesis. - Google Patents
Sistema de electrodo catodico de iontoforesis.Info
- Publication number
- ES2121365T3 ES2121365T3 ES95914740T ES95914740T ES2121365T3 ES 2121365 T3 ES2121365 T3 ES 2121365T3 ES 95914740 T ES95914740 T ES 95914740T ES 95914740 T ES95914740 T ES 95914740T ES 2121365 T3 ES2121365 T3 ES 2121365T3
- Authority
- ES
- Spain
- Prior art keywords
- electrode
- cathodic
- cation exchange
- exchange material
- cathodic electrode
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000005341 cation exchange Methods 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 3
- 229940079593 drug Drugs 0.000 abstract 3
- 239000000463 material Substances 0.000 abstract 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 2
- 230000007935 neutral effect Effects 0.000 abstract 2
- 229910021607 Silver chloride Inorganic materials 0.000 abstract 1
- 125000000129 anionic group Chemical group 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 150000003841 chloride salts Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052802 copper Inorganic materials 0.000 abstract 1
- 239000010949 copper Substances 0.000 abstract 1
- -1 copper cations Chemical class 0.000 abstract 1
- 229910001510 metal chloride Inorganic materials 0.000 abstract 1
- 229910052709 silver Inorganic materials 0.000 abstract 1
- 239000004332 silver Substances 0.000 abstract 1
- HKZLPVFGJNLROG-UHFFFAOYSA-M silver monochloride Chemical compound [Cl-].[Ag+] HKZLPVFGJNLROG-UHFFFAOYSA-M 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0432—Anode and cathode
- A61N1/0436—Material of the electrode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0448—Drug reservoir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0444—Membrane
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Electrotherapy Devices (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE PROPORCIONA UN MONTAJE DE ELECTRODOS DE IONTOFORESIS CATODICOS MEJORADO (38) QUE INCLUYE UN ELECTRODO CATODICO REDUCIBLE (22) Y UN DEPOSITO DE FARMACO (24) QUE CONTIENE UN FARMACO ANIONICO. EL ELECTRODO CATODICO (22) ESTA SEPARADO DEL DEPOSITO DE FARMACO (24) MEDIANTE UNA CAPA (30) DE MATERIAL DE INTERCAMBIO CATIONICO. ESTE MATERIAL DE INTERCAMBIO CATIONICO ESTA CARGADO DE CATIONES CAPACES DE REACCIONAR CON ANIONES PRODUCIDOS EN LA REDUCCION DEL ELECTRODO (22) PARA FORMAR UN COMPUESTO ELECTRICAMENTE NEUTRAL O SUSTANCIALMENTE INSOLUBLE ( P.E. UN COMPUESTO INSOLUBLE EN AGUA ). EL ELECTRODO CATODICO (22) ESTA COMPUESTO PREFERIBLEMENTE DE CLORURO DE PLATA QUE PRODUCE IONES DE CLORURO EN LA REDUCCION. EL MATERIAL DE INTERCAMBIO DE CATIONES ESTA CARGADO CON CATIONES DE PLATA O COBRE QUE REACCIONAN CON LOS IONES DE CLORURO PARA PRODUCIR UNA SAL DE CLORURO DE METAL NEUTRAL Y RELATIVAMENTE INSOLUBLE.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/225,125 US5503632A (en) | 1994-04-08 | 1994-04-08 | Electrotransport device having improved cathodic electrode assembly |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2121365T3 true ES2121365T3 (es) | 1998-11-16 |
Family
ID=22843639
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES95914740T Expired - Lifetime ES2121365T3 (es) | 1994-04-08 | 1995-03-24 | Sistema de electrodo catodico de iontoforesis. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5503632A (es) |
| EP (1) | EP0754077B1 (es) |
| JP (1) | JP3746787B2 (es) |
| AT (1) | ATE170412T1 (es) |
| DE (1) | DE69504486T2 (es) |
| ES (1) | ES2121365T3 (es) |
| WO (1) | WO1995027528A1 (es) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5908400A (en) * | 1996-06-20 | 1999-06-01 | Hisamitsu Pharmaceutical Co., Inc. | Device structure for iontophoresis |
| US6306384B1 (en) * | 1996-10-01 | 2001-10-23 | E-L Management Corp. | Skin battery cosmetic composition |
| KR20000071103A (ko) * | 1997-02-17 | 2000-11-25 | 요시히로 미와 | 이온토포레시스용 디바이스 |
| CA2309955A1 (en) * | 1997-11-12 | 1999-05-20 | Alza Corporation | Method for decreasing self-association of polypeptides |
| US6374136B1 (en) * | 1997-12-22 | 2002-04-16 | Alza Corporation | Anhydrous drug reservoir for electrolytic transdermal delivery device |
| US6059736A (en) * | 1998-02-24 | 2000-05-09 | Tapper; Robert | Sensor controlled analysis and therapeutic delivery system |
| JP2002536132A (ja) * | 1999-02-09 | 2002-10-29 | ピアース・インストルメンツ・インコーポレーテッド | 電気分解装置 |
| KR20010110754A (ko) * | 1999-04-13 | 2001-12-13 | 나까도미 히로다카 | 이온토포레시스 디바이스 |
| US20040109874A1 (en) * | 1999-11-10 | 2004-06-10 | Powderject Vaccines, Inc. | Induction of mucosal immunity by vaccination via the skin route |
| US7734339B2 (en) * | 2002-11-27 | 2010-06-08 | Tokuyama Corporation | Iontophoresis apparatus |
| US20060095001A1 (en) * | 2004-10-29 | 2006-05-04 | Transcutaneous Technologies Inc. | Electrode and iontophoresis device |
| JP4728631B2 (ja) * | 2004-11-30 | 2011-07-20 | Tti・エルビュー株式会社 | イオントフォレーシス装置 |
| US7590444B2 (en) * | 2004-12-09 | 2009-09-15 | Tti Ellebeau, Inc. | Iontophoresis device |
| JP4731931B2 (ja) * | 2005-02-03 | 2011-07-27 | Tti・エルビュー株式会社 | イオントフォレーシス装置 |
| JP4793806B2 (ja) * | 2005-03-22 | 2011-10-12 | Tti・エルビュー株式会社 | イオントフォレーシス装置 |
| JP2006296511A (ja) * | 2005-04-15 | 2006-11-02 | Transcutaneous Technologies Inc | 外用剤、外用剤の塗布方法、イオントフォレーシス装置及び経皮パッチ |
| JP2006334164A (ja) * | 2005-06-02 | 2006-12-14 | Transcutaneous Technologies Inc | イオントフォレーシス装置及びその制御方法 |
| JP2006346368A (ja) * | 2005-06-20 | 2006-12-28 | Transcutaneous Technologies Inc | イオントフォレーシス装置及びその製造方法 |
| JP2007000342A (ja) * | 2005-06-23 | 2007-01-11 | Transcutaneous Technologies Inc | 複数薬剤の投与量および投与時期を制御するイオントフォレーシス装置 |
| US20070027426A1 (en) * | 2005-06-24 | 2007-02-01 | Transcutaneous Technologies Inc. | Iontophoresis device to deliver active agents to biological interfaces |
| US8386030B2 (en) * | 2005-08-08 | 2013-02-26 | Tti Ellebeau, Inc. | Iontophoresis device |
| US20070088331A1 (en) * | 2005-08-18 | 2007-04-19 | Transcutaneous Technologies Inc. | Method and apparatus for managing active agent usage, and active agent injecting device |
| WO2007023907A1 (ja) * | 2005-08-24 | 2007-03-01 | Transcu Ltd. | 冷凍型イオントフォレーシス用電極構造体 |
| EP1925336A4 (en) * | 2005-09-15 | 2011-01-19 | Tti Ellebeau Inc | ROD TYPE IONTOPHORESIS APPARATUS |
| KR20080056200A (ko) * | 2005-09-16 | 2008-06-20 | 티티아이 엘뷰 가부시키가이샤 | 카테터형 이온토포레시스 장치 |
| US20090299264A1 (en) * | 2005-09-28 | 2009-12-03 | Tti Ellebeau, Inc. | Electrode Assembly for Dry Type Iontophoresis |
| US20070135754A1 (en) * | 2005-09-30 | 2007-06-14 | Hidero Akiyama | Electrode assembly for iontophoresis for administering active agent enclosed in nanoparticle and iontophoresis device using the same |
| US20070083147A1 (en) * | 2005-09-30 | 2007-04-12 | Transcutaneous Technologies Inc. | Iontophoresis apparatus and method to deliver antibiotics to biological interfaces |
| US20090299265A1 (en) * | 2005-09-30 | 2009-12-03 | Tti Ellebeau, Inc. | Electrode Assembly for Iontophoresis Having Shape-Memory Separator and Iontophoresis Device Using the Same |
| JP2009509657A (ja) | 2005-09-30 | 2009-03-12 | Tti・エルビュー株式会社 | 生体界面への活性物質の送達のイオントフォレーシス装置及び方法 |
| WO2007037476A1 (ja) * | 2005-09-30 | 2007-04-05 | Tti Ellebeau, Inc. | 睡眠導入剤と興奮剤の投与量および投与時期を制御するイオントフォレーシス装置 |
| CA2622777A1 (en) * | 2005-09-30 | 2007-04-12 | Tti Ellebeau, Inc. | Iontophoresis device to deliver multiple active agents to biological interfaces |
| US20070197955A1 (en) * | 2005-10-12 | 2007-08-23 | Transcutaneous Technologies Inc. | Mucous membrane adhesion-type iontophoresis device |
| JP4732871B2 (ja) * | 2005-11-25 | 2011-07-27 | Tti・エルビュー株式会社 | イオントフォレーシス装置 |
| WO2007079189A2 (en) * | 2005-12-30 | 2007-07-12 | Tti Ellebeau, Inc. | System and method for remote based control of an iontophoresis device |
| KR20090008276A (ko) * | 2006-03-29 | 2009-01-21 | 티티아이 엘뷰 가부시키가이샤 | 이온토포레시스 장치 |
| US20080154230A1 (en) * | 2006-12-20 | 2008-06-26 | Janardhanan Anand Subramony | Anode for electrotransport of cationic drug |
| US8197844B2 (en) | 2007-06-08 | 2012-06-12 | Activatek, Inc. | Active electrode for transdermal medicament administration |
| US20090105634A1 (en) * | 2007-10-17 | 2009-04-23 | Alza Corporation | Anodic Reservoir for Electrotransport of Cationic Drug |
| US20090105632A1 (en) * | 2007-10-18 | 2009-04-23 | Padmanabhan Rama V | Electrotransport Of Lisuride |
| US8862223B2 (en) | 2008-01-18 | 2014-10-14 | Activatek, Inc. | Active transdermal medicament patch and circuit board for same |
| WO2009158032A1 (en) * | 2008-06-25 | 2009-12-30 | Fe2, Inc. | Patches and methods for the transdermal delivery of a therapeutically effective amount of iron |
| ES2481668T3 (es) * | 2008-09-02 | 2014-07-31 | Teikoku Pharma Usa, Inc. | Diseño de electrodo de sacrificio y especie de administración adecuada para periodos prolongados de aplicación de iontoforesis |
| US9008765B2 (en) | 2009-02-12 | 2015-04-14 | Incube Labs, Llc | System and method for biphasic transdermal iontophoretic delivery of therapeutic agents for the control of addictive cravings |
| US8190252B2 (en) | 2009-02-12 | 2012-05-29 | Incube Labs, Llc | Iontophoretic system for transdermal delivery of active agents for therapeutic and medicinal purposes |
| US8961492B2 (en) | 2009-02-12 | 2015-02-24 | Incube Labs, Llc | System and method for controlling the iontophoretic delivery of therapeutic agents based on user inhalation |
| US8348922B2 (en) * | 2009-02-12 | 2013-01-08 | Incube Labs, Llc | Method and apparatus for oscillatory iontophoretic transdermal delivery of a therapeutic agent |
| PL2401027T3 (pl) | 2009-02-26 | 2018-04-30 | The University Of North Carolina At Chapel Hill | Układ do interwencyjnego dostarczania leku |
| US8821945B2 (en) | 2009-04-25 | 2014-09-02 | Fe3 Medical, Inc. | Method for transdermal iontophoretic delivery of chelated agents |
| TW201121604A (en) * | 2009-06-09 | 2011-07-01 | Tti Ellebeau Inc | Long life high capacity electrode, device, and method of manufacture |
| US8417330B2 (en) * | 2009-06-26 | 2013-04-09 | Incube Labs, Llc | Corrosion resistant electrodes for iontophoretic transdermal delivery devices and methods of use |
| WO2011044175A2 (en) | 2009-10-06 | 2011-04-14 | Incube Labs, Llc | Patch and patch assembly for iontophoretic transdermal delivery of active agents for therapeutic and medicinal purposes |
| US8685038B2 (en) | 2009-12-07 | 2014-04-01 | Incube Labs, Llc | Iontophoretic apparatus and method for marking of the skin |
| US8986279B2 (en) | 2010-02-10 | 2015-03-24 | Incube Labs, Llc | Methods and architecture for power optimization of iontophoretic transdermal drug delivery |
| CN106955415B (zh) | 2011-03-24 | 2019-06-18 | 因卡伯实验室有限责任公司 | 用于治疗剂的两阶段经皮离子电渗递送的系统及方法 |
| FR3034017B1 (fr) * | 2015-03-24 | 2018-11-02 | Feeligreen | Matrice polymerique adhesive pour iontophorese et dispositif pour l'iontophorese comprenant ladite matrice |
| US12324792B2 (en) | 2020-12-28 | 2025-06-10 | Smith & Nephew, Inc. | Methods for making and using pharmaceutical compositions for iontophoresis |
| US11883783B2 (en) | 2021-02-26 | 2024-01-30 | Saudi Arabian Oil Company | System and method for electrochemical treatment of aqueous fluid for oilfield applications |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE399044A (es) * | 1933-09-09 | |||
| US3991755A (en) * | 1973-07-27 | 1976-11-16 | Medicon, Inc. | Iontophoresis apparatus for applying local anesthetics |
| US4141359A (en) * | 1976-08-16 | 1979-02-27 | University Of Utah | Epidermal iontophoresis device |
| US4250878A (en) * | 1978-11-22 | 1981-02-17 | Motion Control, Inc. | Non-invasive chemical species delivery apparatus and method |
| JPS56501274A (es) * | 1979-10-10 | 1981-09-10 | ||
| US4383529A (en) * | 1980-11-03 | 1983-05-17 | Wescor, Inc. | Iontophoretic electrode device, method and gel insert |
| JPS5810066A (ja) * | 1981-07-10 | 1983-01-20 | 株式会社アドバンス | イオントフオレ−ゼ用プラスタ−構造体 |
| US4640689A (en) * | 1983-08-18 | 1987-02-03 | Drug Delivery Systems Inc. | Transdermal drug applicator and electrodes therefor |
| US4747819A (en) * | 1984-10-29 | 1988-05-31 | Medtronic, Inc. | Iontophoretic drug delivery |
| US4744787A (en) * | 1984-10-29 | 1988-05-17 | Medtronic, Inc. | Iontophoresis apparatus and methods of producing same |
| US4722726A (en) * | 1986-02-12 | 1988-02-02 | Key Pharmaceuticals, Inc. | Method and apparatus for iontophoretic drug delivery |
| US4752285B1 (en) * | 1986-03-19 | 1995-08-22 | Univ Utah Res Found | Methods and apparatus for iontophoresis application of medicaments |
| US4731049A (en) * | 1987-01-30 | 1988-03-15 | Ionics, Incorporated | Cell for electrically controlled transdermal drug delivery |
| US4878892A (en) * | 1987-02-10 | 1989-11-07 | Drug Delivery Systems Inc. | Electrolytic transdermal delivery of polypeptides |
| US5057072A (en) * | 1988-10-28 | 1991-10-15 | Medtronic, Inc. | Iontophoresis electrode |
| US5084008A (en) * | 1989-12-22 | 1992-01-28 | Medtronic, Inc. | Iontophoresis electrode |
-
1994
- 1994-04-08 US US08/225,125 patent/US5503632A/en not_active Expired - Lifetime
-
1995
- 1995-03-24 WO PCT/US1995/003345 patent/WO1995027528A1/en not_active Ceased
- 1995-03-24 JP JP52634395A patent/JP3746787B2/ja not_active Expired - Fee Related
- 1995-03-24 EP EP95914740A patent/EP0754077B1/en not_active Expired - Lifetime
- 1995-03-24 DE DE69504486T patent/DE69504486T2/de not_active Expired - Lifetime
- 1995-03-24 ES ES95914740T patent/ES2121365T3/es not_active Expired - Lifetime
- 1995-03-24 AT AT95914740T patent/ATE170412T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0754077B1 (en) | 1998-09-02 |
| US5503632A (en) | 1996-04-02 |
| DE69504486T2 (de) | 1999-04-22 |
| JP3746787B2 (ja) | 2006-02-15 |
| ATE170412T1 (de) | 1998-09-15 |
| WO1995027528A1 (en) | 1995-10-19 |
| JPH09511662A (ja) | 1997-11-25 |
| EP0754077A1 (en) | 1997-01-22 |
| DE69504486D1 (de) | 1998-10-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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