ES2123162T3 - Aparato y procedimiento de transferencia de una muestra fluida. - Google Patents
Aparato y procedimiento de transferencia de una muestra fluida.Info
- Publication number
- ES2123162T3 ES2123162T3 ES94931783T ES94931783T ES2123162T3 ES 2123162 T3 ES2123162 T3 ES 2123162T3 ES 94931783 T ES94931783 T ES 94931783T ES 94931783 T ES94931783 T ES 94931783T ES 2123162 T3 ES2123162 T3 ES 2123162T3
- Authority
- ES
- Spain
- Prior art keywords
- reaction
- nucleic acid
- detection
- chamber
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000012530 fluid Substances 0.000 title 1
- 238000001514 detection method Methods 0.000 abstract 7
- 150000007523 nucleic acids Chemical class 0.000 abstract 4
- 102000039446 nucleic acids Human genes 0.000 abstract 4
- 108020004707 nucleic acids Proteins 0.000 abstract 4
- 238000010438 heat treatment Methods 0.000 abstract 2
- 238000005382 thermal cycling Methods 0.000 abstract 2
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 238000007619 statistical method Methods 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
- G01N2035/00237—Handling microquantities of analyte, e.g. microvalves, capillary networks
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00346—Heating or cooling arrangements
- G01N2035/00356—Holding samples at elevated temperature (incubation)
- G01N2035/00366—Several different temperatures used
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00346—Heating or cooling arrangements
- G01N2035/00356—Holding samples at elevated temperature (incubation)
- G01N2035/00376—Conductive heating, e.g. heated plates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
- G01N2035/00742—Type of codes
- G01N2035/00752—Type of codes bar codes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/808—Optical sensing apparatus
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Sampling And Sample Adjustment (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Devices For Use In Laboratory Experiments (AREA)
Abstract
SE PROPORCIONAN METODOS, DISPOSITIVOS, APARATOS Y JUEGOS PARA AMPLIAR Y DETECTAR ACIDO NUCLEICO. EL APARATO ES UN DISPOSITIVO CICLICO TERMICO (16) DE UNA O DOS FILAS QUE FUNCIONA EN CONJUNCION CON UNA UNIDAD DE REACCION/DETECCION (20). UNA MUESTRA (38) ES CARGADA EN UNA CAMARA DE REACCION (30) DEL DISPOSITIVO QUE ES ENTONCES UNIDO CON UNA CAMARA DE DETECCION (32) PARA FORMAR LA UNIDAD DE REACCION/DETECCION. UN PRIMER ELEMENTO DE CALENTAMIENTO (90) DEL APARATO CICLICO TERMICO APLICA UNA TEMPERATURA DESEADA AL DISPOSITIVO DE REACCION/DETECCION PARA AMPLIAR EL ACIDO NUCLEICO DIANA EN LA MUESTRA. LA MEZCLA DE REACCION ES ENTONCES TRANSFERIDA A LA CAMARA DE DETECCION POR EL SEGUNDO ELEMENTO DE CALENTAMIENTO (92) Y EL ACIDO NUCLEICO DIANA AMPLIADO ES INMOVILIZADO EN UN SOPORTE EN LA CAMARA DE DETECCION. EL CONTROL DE MICROPROCESADOR CONTROLA EL CALOR APLICADO POR EL SEGUNDO ELEMENTO INDEPENDIENTEMENTE DEL CALOR APLICADO POR EL PRIMER ELEMENTO. UN SISTEMA DE DETECCION ASOCIADO CON EL APARATO DETECTA Y ANALIZA EL OBJETIVO DE ACIDO NUCLEICO AMPLIADO INMOVILIZADO. IMAGENES SON CAPTURADAS Y DIGITALIZADAS Y SOMETIDAS A ANALISIS ESTADISTICOS PARA MEJORAR LA SEGURIDAD DEL METODO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14073093A | 1993-10-21 | 1993-10-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2123162T3 true ES2123162T3 (es) | 1999-01-01 |
Family
ID=22492549
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES94931783T Expired - Lifetime ES2123162T3 (es) | 1993-10-21 | 1994-09-28 | Aparato y procedimiento de transferencia de una muestra fluida. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6068978A (es) |
| EP (1) | EP0724717B1 (es) |
| JP (1) | JP3741439B2 (es) |
| AT (1) | ATE170001T1 (es) |
| AU (1) | AU8073294A (es) |
| DE (1) | DE69412632T2 (es) |
| ES (1) | ES2123162T3 (es) |
| WO (1) | WO1995011437A1 (es) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7040653B1 (en) * | 2004-10-27 | 2006-05-09 | Automotive Technologies International, Inc. | Steering wheel assemblies for vehicles |
| GB9719673D0 (en) * | 1997-09-17 | 1997-11-19 | Glaxo Group Ltd | Novel apparatus |
| JP4511034B2 (ja) | 1998-05-01 | 2010-07-28 | ジェン−プロウブ インコーポレイテッド | 自動化診断用分析器および方法 |
| US8337753B2 (en) | 1998-05-01 | 2012-12-25 | Gen-Probe Incorporated | Temperature-controlled incubator having a receptacle mixing mechanism |
| JP4045475B2 (ja) * | 1999-09-06 | 2008-02-13 | 東洋紡績株式会社 | 核酸・蛋白質精製装置 |
| US6620625B2 (en) * | 2000-01-06 | 2003-09-16 | Caliper Technologies Corp. | Ultra high throughput sampling and analysis systems and methods |
| US20020031836A1 (en) * | 2000-09-11 | 2002-03-14 | Feldstein Mark J. | Fluidics system |
| US7402282B2 (en) | 2001-07-20 | 2008-07-22 | Ortho-Clinical Diagnostics, Inc. | Auxiliary sample supply for a clinical analyzer |
| US6637476B2 (en) | 2002-04-01 | 2003-10-28 | Protedyne Corporation | Robotically manipulable sample handling tool |
| US20040053318A1 (en) * | 2002-09-17 | 2004-03-18 | Mcwilliams Diana R. | Preservation of RNA and reverse transcriptase during automated liquid handling |
| US7249529B2 (en) * | 2003-03-28 | 2007-07-31 | Protedyne Corporation | Robotically manipulable sample handling tool |
| WO2006099255A2 (en) | 2005-03-10 | 2006-09-21 | Gen-Probe Incorporated | Systems and methods to perform assays for detecting or quantifying analytes within samples |
| DE102005028897A1 (de) * | 2005-06-17 | 2006-12-28 | Eckert & Ziegler Eurotope Gmbh | Anordnung und Verfahren zur Verarbeitung von chemischen Stoffen, Computerprogramm zur Steuerung einer solchen Anordnung sowie ein entsprechendes computerlesbares Speichermedium |
| CN1888902B (zh) * | 2006-08-11 | 2011-05-18 | 杭州优思达生物技术有限公司 | 全封闭式靶核酸扩增物快速检测装置 |
| US8962306B2 (en) * | 2006-09-08 | 2015-02-24 | Thermo Fisher Scientific Oy | Instruments and method relating to thermal cycling |
| EP2752670A2 (en) | 2010-07-23 | 2014-07-09 | Beckman Coulter, Inc. | System or method of including analytical units |
| US9046507B2 (en) | 2010-07-29 | 2015-06-02 | Gen-Probe Incorporated | Method, system and apparatus for incorporating capacitive proximity sensing in an automated fluid transfer procedure |
| US9266110B2 (en) * | 2010-10-14 | 2016-02-23 | Genereach Biotechnology Corp. | Reaction tube for performing isothermal polymerase chain reaction therein |
| CN103403533B (zh) | 2011-02-24 | 2017-02-15 | 简.探针公司 | 用于分辨光信号检测器中不同调制频率的光信号的系统和方法 |
| GB2493981A (en) * | 2011-08-26 | 2013-02-27 | Isis Innovation | Temperature controlled analyte transferring device |
| EP2776846B1 (en) | 2011-11-07 | 2019-08-21 | Beckman Coulter, Inc. | Aliquotter system and workflow |
| CN104053997B (zh) | 2011-11-07 | 2016-12-21 | 贝克曼考尔特公司 | 用于处理样本的系统和方法 |
| BR112014011046A2 (pt) | 2011-11-07 | 2017-06-13 | Beckman Coulter, Inc. | fluxo de trabalho e sistema de centrífuga |
| US8973736B2 (en) | 2011-11-07 | 2015-03-10 | Beckman Coulter, Inc. | Magnetic damping for specimen transport system |
| US9046506B2 (en) | 2011-11-07 | 2015-06-02 | Beckman Coulter, Inc. | Specimen container detection |
| ES2844324T3 (es) | 2011-11-07 | 2021-07-21 | Beckman Coulter Inc | Brazo robótico |
| AU2013202808B2 (en) | 2012-07-31 | 2014-11-13 | Gen-Probe Incorporated | System and method for performing multiplex thermal melt analysis |
| EP4109106B1 (en) | 2013-03-15 | 2025-06-18 | Abbott Laboratories | Automated diagnostic analyzers having vertically arranged carousels and related methods |
| ES2988248T3 (es) | 2013-03-15 | 2024-11-19 | Abbott Lab | Analizadores de diagnóstico automatizados que tienen sistemas de pista accesibles por la parte posterior y métodos relacionados |
| CN108196079B (zh) | 2013-03-15 | 2021-10-08 | 雅培制药有限公司 | 具有预处理转盘的诊断分析机及相关方法 |
| US9267869B2 (en) * | 2013-08-07 | 2016-02-23 | Aerodyne Research, Inc. | Particle capture device |
| US10427162B2 (en) | 2016-12-21 | 2019-10-01 | Quandx Inc. | Systems and methods for molecular diagnostics |
| EP3581936B1 (en) * | 2017-02-07 | 2022-07-13 | Hitachi High-Tech Corporation | Automatic analysis device |
| US11199527B2 (en) | 2017-03-28 | 2021-12-14 | Nec Corporation | Microtube |
| JP7238300B2 (ja) * | 2018-09-04 | 2023-03-14 | 株式会社島津製作所 | 分析システム、表示制御方法および表示制御プログラム |
| CN114031147B (zh) * | 2021-11-02 | 2022-06-14 | 航天环保(北京)有限公司 | 利用波裂解纳米材料提升水质的方法及系统 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2341649B1 (fr) * | 1976-02-19 | 1979-07-20 | Inst Nat Sante Rech Med | Procede de recherche bacteriologique |
| US5229297A (en) * | 1989-02-03 | 1993-07-20 | Eastman Kodak Company | Containment cuvette for PCR and method of use |
| CA1338505C (en) * | 1989-02-03 | 1996-08-06 | John Bruce Findlay | Containment cuvette for pcr and method of use |
| GB8917963D0 (en) * | 1989-08-05 | 1989-09-20 | Scras | Apparatus for repeated automatic execution of a thermal cycle for treatment of biological samples |
| DE4024148A1 (de) * | 1990-07-30 | 1992-02-06 | Merck Patent Gmbh | Schrauben fuer gelenkoperationen |
| DE4024545A1 (de) * | 1990-08-02 | 1992-02-06 | Boehringer Mannheim Gmbh | Verfahren und vorrichtung zum dosierten zufuehren einer biochemischen analysefluessigkeit auf ein target |
| US5210015A (en) * | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| US5160413A (en) * | 1990-08-16 | 1992-11-03 | Conoco Inc. | Micro-distillation process for cyanide |
| RU2017821C1 (ru) * | 1990-10-10 | 1994-08-15 | Анатолий Михайлович Онищенко | Способ амплификации днк и устройство для его осуществления |
| FR2672301A1 (fr) * | 1991-02-01 | 1992-08-07 | Larzul Daniel | Procede et dispositif pour amplifier le nombre d'une sequence definie d'acide nucleique dans un echantillon biologique. |
| WO1992020778A1 (en) * | 1991-05-24 | 1992-11-26 | Kindconi Pty Limited | Biochemical reaction control |
-
1994
- 1994-09-28 WO PCT/US1994/011016 patent/WO1995011437A1/en not_active Ceased
- 1994-09-28 DE DE69412632T patent/DE69412632T2/de not_active Expired - Fee Related
- 1994-09-28 AU AU80732/94A patent/AU8073294A/en not_active Abandoned
- 1994-09-28 JP JP51184995A patent/JP3741439B2/ja not_active Expired - Fee Related
- 1994-09-28 EP EP94931783A patent/EP0724717B1/en not_active Expired - Lifetime
- 1994-09-28 ES ES94931783T patent/ES2123162T3/es not_active Expired - Lifetime
- 1994-09-28 AT AT94931783T patent/ATE170001T1/de not_active IP Right Cessation
-
1997
- 1997-05-20 US US08/859,552 patent/US6068978A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU8073294A (en) | 1995-05-08 |
| WO1995011437A1 (en) | 1995-04-27 |
| JP3741439B2 (ja) | 2006-02-01 |
| ATE170001T1 (de) | 1998-09-15 |
| US6068978A (en) | 2000-05-30 |
| DE69412632T2 (de) | 1999-01-14 |
| EP0724717B1 (en) | 1998-08-19 |
| EP0724717A1 (en) | 1996-08-07 |
| JPH09504428A (ja) | 1997-05-06 |
| DE69412632D1 (de) | 1998-09-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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