ES2124878T3 - Alergeno recombinante del polen del fleo $i (phl p) ii. - Google Patents

Alergeno recombinante del polen del fleo $i (phl p) ii.

Info

Publication number
ES2124878T3
ES2124878T3 ES94910269T ES94910269T ES2124878T3 ES 2124878 T3 ES2124878 T3 ES 2124878T3 ES 94910269 T ES94910269 T ES 94910269T ES 94910269 T ES94910269 T ES 94910269T ES 2124878 T3 ES2124878 T3 ES 2124878T3
Authority
ES
Spain
Prior art keywords
phl
fleo
pollen
molecula
recombinant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94910269T
Other languages
English (en)
Inventor
Christiane Dolecek
Susanne Vrtala
Sylvia Laffer
Peter Steinberger
Dietrich Kraft
Otto Scheiner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomay AG
Original Assignee
Biomay AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3496784&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2124878(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biomay AG filed Critical Biomay AG
Application granted granted Critical
Publication of ES2124878T3 publication Critical patent/ES2124878T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Disinfection, Sterilisation Or Deodorisation Of Air (AREA)

Abstract

LA INVENCION SE REFIERE A UNA MOLECULA RECOMBINANTE DNA, QUE CODIFICA UN PEPTIDO CON CAPACIDAD ANTIGENA DE ALERGIA DE POLEN DE HIERBA PHL P II. PARA ELLO SE DERIVA LA SECUENCIA DE AMINOACIDOS, LAS CELULAS B IMPORTANTES Y LOS EPITOPES DE CELULA T DE LA MOLECULA. EL FACTOR DE ALERGIA RECOMBINANTE SE EXPRESA EN EL ESQUERIQUIA COLI Y SE UNE AL SERUM IGE DE MAS DEL 60 % DE TODOS LOS FACTORES DE ALERGIA DEL POLEN DE HIERBA Y PUEDE POR TANTO SER UTILIZADO EN LA MISMA FORMA COMO OCURRE NATURALMENTE CON EL PHL P II PARA PROCESOS BASADOS EN INTERACCION DE ANTICUERPOS ANTIGENOS, LIBERANDO UN MEDIADOR Y UNA REACTIVIDAD DE CELULA T.
ES94910269T 1993-04-01 1994-03-31 Alergeno recombinante del polen del fleo $i (phl p) ii. Expired - Lifetime ES2124878T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0067293A AT401937B (de) 1993-04-01 1993-04-01 Rekombinantes lieschgras pollen allergen phl p ii
PCT/AT1994/000039 WO1994023035A2 (de) 1993-04-01 1994-03-31 REKOMBINANTES LIESCHGRASPOLLENALLERGEN Phl p II

Publications (1)

Publication Number Publication Date
ES2124878T3 true ES2124878T3 (es) 1999-02-16

Family

ID=3496784

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94910269T Expired - Lifetime ES2124878T3 (es) 1993-04-01 1994-03-31 Alergeno recombinante del polen del fleo $i (phl p) ii.

Country Status (12)

Country Link
EP (1) EP0643769B1 (es)
JP (1) JP3657604B2 (es)
AT (2) AT401937B (es)
AU (1) AU684269B2 (es)
CA (1) CA2136973A1 (es)
DE (1) DE59406999D1 (es)
DK (1) DK0643769T3 (es)
ES (1) ES2124878T3 (es)
FI (1) FI945648A7 (es)
NO (1) NO944634L (es)
SI (1) SI0643769T1 (es)
WO (1) WO1994023035A2 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE430199T1 (de) 1998-01-31 2009-05-15 Univ Arkansas Verfahren und reagenzien zur verminderung der klinischen reaktion zur allergie
DE19939982A1 (de) * 1999-08-24 2001-03-01 Merck Patent Gmbh Verfahren zur Isolierung und Aufreinigung von Gräserpollenallergenen
SE0200946D0 (sv) * 2002-03-27 2002-03-27 Pharmacia Diagnostics Ab Novel Allergen
ATE307141T1 (de) * 2003-01-21 2005-11-15 Biomay Prod & Handel Verfahren zur vorbereitung von hypoallergenen mosaikproteine
US8709435B2 (en) 2003-01-21 2014-04-29 Biomay Ag Hypallergenic mosaic antigens and methods of making same
AT503296B1 (de) * 2006-05-03 2007-09-15 Biomay Ag Protein-allergen-derivat
AT503690A1 (de) * 2006-06-09 2007-12-15 Biomay Ag Hypoallergene moleküle

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340729C (en) * 1988-03-23 1999-09-07 Mohan Bir Singh Ryegrass pollen allergen

Also Published As

Publication number Publication date
ATE171725T1 (de) 1998-10-15
JPH08500492A (ja) 1996-01-23
AU684269B2 (en) 1997-12-11
DK0643769T3 (da) 1999-06-21
WO1994023035A3 (de) 1994-11-24
SI0643769T1 (en) 1999-04-30
NO944634L (no) 1995-01-23
FI945648A7 (fi) 1995-01-25
FI945648A0 (fi) 1994-11-30
JP3657604B2 (ja) 2005-06-08
CA2136973A1 (en) 1994-10-13
AT401937B (de) 1996-12-27
ATA67293A (de) 1996-05-15
DE59406999D1 (de) 1998-11-05
NO944634D0 (no) 1994-12-01
EP0643769A1 (de) 1995-03-22
AU6276894A (en) 1994-10-24
EP0643769B1 (de) 1998-09-30
WO1994023035A2 (de) 1994-10-13

Similar Documents

Publication Publication Date Title
AR038568A1 (es) Anticuerpos anti-a beta y su uso
ES2165851T3 (es) Proteinas multivalentes que se unen a antigenos.
ATE468127T1 (de) Ii-key/antigene epitop-hybrid-peptid-vakzine
AR047729A1 (es) Anticuerpos terapeuticos que se unen a la apolipoproteina e (apoe)
ES2071315T3 (es) Proteasa especifica de ubiquitina.
AR018603A1 (es) Un peptido, util para el tratamiento y/o profilaxis de la enfermedad de alzheimer y el sindrome de down, las composiciones farmaceuticas y vacunas que locontienen, el uso de dicho peptido para la preparacion de las composiciones farmaceuticas, una secuencia de aislado de adn, un plasmido o vector vi
ES2112838T3 (es) Peptidos receptores de celulas t como agentes terapeuticos para enfermedades autoinmunitarias y malignas.
ID28299A (id) Protein-protein reseptor seperti toll manusia metoda-metoda dan reagen-reagen yang berhubungan
DE69535035D1 (de) Präparate zur verabreichung von genetischem material
HUP9800075A2 (hu) Nukleinsav-konstrukciók proteázokkal aktíválható hatóanyagok expresszálására valamint előállításuk és alkalmazásuk
ES8800266A1 (es) Un metodo para obtener un polipeptido complementario de al menos una porcion de un peptido o proteina original
ATE404583T1 (de) Funktionelle antagonisten von hedgehog-aktivität
RU98120519A (ru) Аутоантиген и структурно-родственные ему белки для применения при иммунотерапии аутоиммунных заболеваний
BR9709958A (pt) Polipeptídeos capaz de formar estruturas de ligaçãode antígeno com especificidade para os antígenos de rhesus d o dna que os codifica e o processo para sua preparação e uso
ATE122394T1 (de) Pankreatische isletzellen-antigene, erhalten durch molekulare klonierung.
ATE337791T1 (de) Das einbringen von nukleinsäuremolekülen in schleimhautgewebe
ATE189961T1 (de) Impfstoff gegen mycobakterielle infektionen
AR002742A1 (es) Proteina reguladora del tipo adiposo, procedimiento para producir dicha proteina, formulaciones farmaceuticas que la incluyen, molecula de adn aisladaque codifica dicha proteina, vector y celulas recombinantes que comprenden dicho adn
AR019864A1 (es) Proceso para producir el antigeno de toxoplasma sag1 o fragmentos del mismo; proteina sag1 o fragmentos de la misma expresada en dicho proceso;composiciones de vacuna que comprendan dicha proteina sag1 o fragmentos de la misma; uso de dicha proteina para la manufactura de medicamentos para preveniry
ATE171725T1 (de) Rekombinantes lieschgraspollenallergen -i(phl p) ii
SE9703531D0 (sv) Non-anaphlactic forms of allergens and their use
IL75553A (en) Dna sequence coding for a cholinesterase-like peptide, peptides produced by cells containing said dna and antibodies thereto
ES2060134T3 (es) Inhibidor de tejido de metaloproteasas (timp-2).
ATE324448T1 (de) Design von immunogene
AR248047A1 (es) Procedimiento para la preparacion de una vacuna a base de virus del herpes bovina modificado tipo 1.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 643769

Country of ref document: ES