ES2130575T3 - Composiciones inmunogenicas mejoradas contra la gastrina 17 humana. - Google Patents

Composiciones inmunogenicas mejoradas contra la gastrina 17 humana.

Info

Publication number
ES2130575T3
ES2130575T3 ES95902570T ES95902570T ES2130575T3 ES 2130575 T3 ES2130575 T3 ES 2130575T3 ES 95902570 T ES95902570 T ES 95902570T ES 95902570 T ES95902570 T ES 95902570T ES 2130575 T3 ES2130575 T3 ES 2130575T3
Authority
ES
Spain
Prior art keywords
gastrine
against human
pro
immunogenic compositions
compositions against
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95902570T
Other languages
English (en)
Inventor
Philip C Gevas
Stephen Grimes
Stephen L Karr
Dov Michaeli
Robert Scibienski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aphton Corp
Original Assignee
Aphton Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aphton Corp filed Critical Aphton Corp
Application granted granted Critical
Publication of ES2130575T3 publication Critical patent/ES2130575T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/595—Gastrins; Cholecystokinins [CCK]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/843—Digestive system
    • Y10S530/844—Stomach; intestine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

UNA COMPOSICION INMUNOGENICA MEJORADA CONTRA LA GASTRINA 17 HUMANA QUE CONTIENE EL PEPTIDO PGLU - GLY - PRO - TRP - LEU - GLU - GLU - GLU - GLU - SER - SER - PRO - PRO - PRO - PRO CYS (N POSICIONES FARMACEUTICAS QUE LA CONTIENEN.
ES95902570T 1993-11-12 1994-11-10 Composiciones inmunogenicas mejoradas contra la gastrina 17 humana. Expired - Lifetime ES2130575T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/151,219 US5468494A (en) 1993-11-12 1993-11-12 Immunogenic compositions against human gastrin 17

Publications (1)

Publication Number Publication Date
ES2130575T3 true ES2130575T3 (es) 1999-07-01

Family

ID=22537815

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95902570T Expired - Lifetime ES2130575T3 (es) 1993-11-12 1994-11-10 Composiciones inmunogenicas mejoradas contra la gastrina 17 humana.

Country Status (10)

Country Link
US (1) US5468494A (es)
EP (1) EP0728148B1 (es)
JP (1) JP3694893B2 (es)
AT (1) ATE177757T1 (es)
AU (1) AU1179795A (es)
DE (1) DE69417252T2 (es)
DK (1) DK0728148T3 (es)
ES (1) ES2130575T3 (es)
GR (1) GR3029791T3 (es)
WO (1) WO1995013297A2 (es)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6861510B1 (en) * 1989-01-24 2005-03-01 Aphton Corporation Immunogenic compositions against gastrin peptides
ES2063912T3 (es) * 1989-01-24 1995-01-16 Aphton Corp Composiciones inmunogenicas frente a peptidos de gastrina.
CA2261433A1 (en) * 1993-12-09 1995-06-10 Belinda Sanchez Ramirez Composition comprising autologous epidermal growth factor
US5688506A (en) * 1994-01-27 1997-11-18 Aphton Corp. Immunogens against gonadotropin releasing hormone
ATE505202T1 (de) * 1996-02-08 2011-04-15 Cancer Advances Inc Immunologische methoden zur behandlung von gastrointestinalem krebs
US20040001842A1 (en) * 1997-05-12 2004-01-01 Dov Michaeli Immunogenic compositions to the CCK-B/gastrin receptor and methods for the treatment of tumors
ES2227833T3 (es) 1997-05-12 2005-04-01 Aphton Corporation Composiciones inmunogenicas para el receptor cck-b/gastrina y metodos para el tratamiento de tumores.
US20030068326A1 (en) * 1998-05-15 2003-04-10 Aphton Corporation Method for the treatment of gastroesophageal reflux disease
AU4080399A (en) * 1998-05-15 1999-12-06 Aphton Corporation Prevention and treatment of hypergastrinemia
CA2332774A1 (en) * 1998-05-15 1999-11-25 Dov Michaeli Method for the treatment of gastroesophageal reflux disease
KR100699574B1 (ko) * 1998-05-15 2007-03-23 리셉터 바이오로직스 인크 종양 치료를 위한 조합 치료
US20020058040A1 (en) * 1999-12-23 2002-05-16 Stephen Grimes Stable immunogenic composition for frozen storage
EP1303533A2 (en) * 2000-05-05 2003-04-23 Aphton Corporation Chimeric peptide immunogens, their preparation and use
JP2005508838A (ja) * 2001-03-23 2005-04-07 アフトン コーポレーション 膵癌の組合せ治療
CU22999A1 (es) * 2001-12-04 2004-10-12 Centro Inmunologia Molecular Método de tratamiento de enfermedades malignas e infecciosas crónicas
US20090191232A1 (en) * 2001-05-04 2009-07-30 Gevas Philip C Combination therapy for the treatment of tumors
JP2004536835A (ja) * 2001-07-09 2004-12-09 アフトン コーポレーション 肝臓、肺および食道の癌性ならびに前癌性状態の治療および防止
US20040247661A1 (en) * 2002-07-03 2004-12-09 Dov Michaeli Liposomal vaccine
US20040208920A1 (en) * 2002-07-03 2004-10-21 Dov Michaeli Liposomal vaccine
US20050169979A1 (en) * 2002-07-03 2005-08-04 Dov Michaeli Liposomal vaccine
JP4689597B2 (ja) 2003-03-28 2011-05-25 レセプター バイオロジックス インク． ガストリンホルモン免疫アッセイ
KR101333168B1 (ko) 2004-09-22 2013-11-28 리셉터 바이오로직스 인크 프로가스트린에 대한 모노클로날 항체
CL2007002166A1 (es) * 2006-07-24 2008-01-25 Tetralogic Pharm Corp Compuestos derivados de heterociclos de nitrogeno, antagonistas de los inhibidores de las proteinas de la apoptosis; sus composiciones farmaceuticas; y uso de dichos compuestos para el tratamiento del cancer.
CA2703787C (en) * 2007-10-26 2016-08-23 Advanced Life Science Institute, Inc. Antibody directed against pro-gastrin releasing peptide, and use thereof
US9498522B2 (en) 2008-08-07 2016-11-22 Mercia Pharma Inc. Immunotherapeutic compositions for the treatment of alzheimer'S disease
US8283372B2 (en) 2009-07-02 2012-10-09 Tetralogic Pharmaceuticals Corp. 2-(1H-indol-3-ylmethyl)-pyrrolidine dimer as a SMAC mimetic
US8674064B2 (en) * 2010-03-03 2014-03-18 Onkologix Ltd Immunogenic compositions against human progastrin peptides
CN101797382B (zh) * 2010-03-03 2013-11-20 戚胜美 抗人前胃液素多肽免疫组合物
GB201121571D0 (en) 2011-12-15 2012-01-25 Astrimmune Ltd Compounds and uses thereof
ES2665780T3 (es) 2013-05-21 2018-04-27 Tyg Oncology Ltd. Composición inmunogénica de péptido de gastrina
WO2018232230A1 (en) 2017-06-15 2018-12-20 Cancer Advances Inc. Compositions and methods for inducing humoral and cellular immunities against tumors and cancer
US12150978B2 (en) 2017-06-15 2024-11-26 Cancer Advances Inc. Compositions and methods for preventing tumors and cancer
EP4225346A4 (en) * 2020-11-06 2025-01-01 Cancer Advances, Inc., Compositions and methods for enhancing t cell penetration of tumors and cancers

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4691006A (en) * 1983-03-04 1987-09-01 Ohio State University Antigenic modification of polypeptides
US4201770A (en) * 1973-05-07 1980-05-06 The Ohio State University Antigenic modification of polypeptides
US4384995A (en) * 1980-01-16 1983-05-24 The Ohio State University Antigenic modification of polypeptides
US4526716A (en) * 1981-11-20 1985-07-02 The Ohio State University Antigenic modification of polypeptides
US4069313A (en) * 1974-11-19 1978-01-17 Merck & Co., Inc. Water-in-oil adjuvant composition
US4894443A (en) * 1984-02-08 1990-01-16 Cetus Corporation Toxin conjugates
ES2063912T3 (es) * 1989-01-24 1995-01-16 Aphton Corp Composiciones inmunogenicas frente a peptidos de gastrina.
US5023077A (en) * 1989-01-24 1991-06-11 Aphton Corporation Immunogenic compositions and methods for the treatment and prevention of gastric and duodenal ulcer disease
US5120829A (en) * 1989-03-20 1992-06-09 La Jolla Cancer Research Foundation Hydrophobic attachment site for adhesion peptides
US5256542A (en) * 1992-03-09 1993-10-26 Tanox Biosystems, Inc. Selecting low frequency antigen-specific single B lymphocytes with correction for background noise

Also Published As

Publication number Publication date
EP0728148B1 (en) 1999-03-17
ATE177757T1 (de) 1999-04-15
DE69417252T2 (de) 1999-07-08
JP3694893B2 (ja) 2005-09-14
DE69417252D1 (de) 1999-04-22
WO1995013297A3 (en) 1995-06-15
JPH09505056A (ja) 1997-05-20
AU1179795A (en) 1995-05-29
US5468494A (en) 1995-11-21
EP0728148A1 (en) 1996-08-28
GR3029791T3 (en) 1999-06-30
WO1995013297A2 (en) 1995-05-18
DK0728148T3 (da) 1999-09-27

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