ES2130575T3 - Composiciones inmunogenicas mejoradas contra la gastrina 17 humana. - Google Patents

Composiciones inmunogenicas mejoradas contra la gastrina 17 humana.

Info

Publication number
ES2130575T3
ES2130575T3 ES95902570T ES95902570T ES2130575T3 ES 2130575 T3 ES2130575 T3 ES 2130575T3 ES 95902570 T ES95902570 T ES 95902570T ES 95902570 T ES95902570 T ES 95902570T ES 2130575 T3 ES2130575 T3 ES 2130575T3
Authority
ES
Spain
Prior art keywords
gastrine
against human
pro
immunogenic compositions
compositions against
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95902570T
Other languages
English (en)
Inventor
Philip C Gevas
Stephen Grimes
Stephen L Karr
Dov Michaeli
Robert Scibienski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aphton Corp
Original Assignee
Aphton Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aphton Corp filed Critical Aphton Corp
Application granted granted Critical
Publication of ES2130575T3 publication Critical patent/ES2130575T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/595—Gastrins; Cholecystokinins [CCK]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/843—Digestive system
    • Y10S530/844—Stomach; intestine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

UNA COMPOSICION INMUNOGENICA MEJORADA CONTRA LA GASTRINA 17 HUMANA QUE CONTIENE EL PEPTIDO PGLU - GLY - PRO - TRP - LEU - GLU - GLU - GLU - GLU - SER - SER - PRO - PRO - PRO - PRO CYS (N POSICIONES FARMACEUTICAS QUE LA CONTIENEN.
ES95902570T 1993-11-12 1994-11-10 Composiciones inmunogenicas mejoradas contra la gastrina 17 humana. Expired - Lifetime ES2130575T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/151,219 US5468494A (en) 1993-11-12 1993-11-12 Immunogenic compositions against human gastrin 17

Publications (1)

Publication Number Publication Date
ES2130575T3 true ES2130575T3 (es) 1999-07-01

Family

ID=22537815

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95902570T Expired - Lifetime ES2130575T3 (es) 1993-11-12 1994-11-10 Composiciones inmunogenicas mejoradas contra la gastrina 17 humana.

Country Status (10)

Country Link
US (1) US5468494A (es)
EP (1) EP0728148B1 (es)
JP (1) JP3694893B2 (es)
AT (1) ATE177757T1 (es)
AU (1) AU1179795A (es)
DE (1) DE69417252T2 (es)
DK (1) DK0728148T3 (es)
ES (1) ES2130575T3 (es)
GR (1) GR3029791T3 (es)
WO (1) WO1995013297A2 (es)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0380230T3 (da) * 1989-01-24 1995-01-16 Aphton Corp Immunogene sammensætninger mod gastrin-peptider
US6861510B1 (en) * 1989-01-24 2005-03-01 Aphton Corporation Immunogenic compositions against gastrin peptides
CA2261433A1 (en) * 1993-12-09 1995-06-10 Belinda Sanchez Ramirez Composition comprising autologous epidermal growth factor
US5688506A (en) * 1994-01-27 1997-11-18 Aphton Corp. Immunogens against gonadotropin releasing hormone
ES2361474T3 (es) * 1996-02-08 2011-06-17 Cancer Advances, Inc. Procedimientos inmunológicos para el tratamiento del cáncer gastrointestinal.
HUP0002760A3 (en) * 1997-05-12 2003-03-28 Aphton Corp Woodland Immunogenic compositions to the cck-b/gastrin-receptor and methods for the treatment of tumors
US20040001842A1 (en) * 1997-05-12 2004-01-01 Dov Michaeli Immunogenic compositions to the CCK-B/gastrin receptor and methods for the treatment of tumors
EP1077716B1 (en) * 1998-05-15 2005-07-27 Aphton Corporation Preparation of a medicament for the treatment of gastroesophageal reflux disease
CA2328501A1 (en) * 1998-05-15 1999-11-25 Aphton Corporation Prevention and treatment of hypergastrinemia
EP1076561B1 (en) * 1998-05-15 2005-03-30 Aphton Corporation Combination therapy for the treatment of tumors
US20030068326A1 (en) * 1998-05-15 2003-04-10 Aphton Corporation Method for the treatment of gastroesophageal reflux disease
WO2001045670A2 (en) * 1999-12-23 2001-06-28 Aphton Corporation A stable immunogenic composition for frozen storage
JP2003532740A (ja) * 2000-05-05 2003-11-05 アフトン コーポレーション キメラペプチド免疫原
CA2441228A1 (en) * 2001-03-23 2002-10-03 Aphton Corporation Combination treatment of pancreatic cancer
CU22999A1 (es) * 2001-12-04 2004-10-12 Centro Inmunologia Molecular Método de tratamiento de enfermedades malignas e infecciosas crónicas
US20090191232A1 (en) * 2001-05-04 2009-07-30 Gevas Philip C Combination therapy for the treatment of tumors
US20030021786A1 (en) * 2001-07-09 2003-01-30 Gevas Philip C. Treatment and prevention of cancerous and pre-cancerous conditions of the liver, lung and esophagus
US20050169979A1 (en) * 2002-07-03 2005-08-04 Dov Michaeli Liposomal vaccine
WO2004004687A2 (en) * 2002-07-03 2004-01-15 Aphton Corporation Liposomal vaccine
US20040247661A1 (en) * 2002-07-03 2004-12-09 Dov Michaeli Liposomal vaccine
WO2004088326A2 (en) * 2003-03-28 2004-10-14 Aphton Corporation Gastrin hormone immunoassays
DK1794586T3 (da) 2004-09-22 2013-05-13 Cancer Advances Inc Monoklonale antistoffer til progastrin
JP5452223B2 (ja) * 2006-07-24 2014-03-26 テトラロジック ファーマシューティカルズ コーポレーション Ｉａｐ阻害剤
US8609424B2 (en) * 2007-10-26 2013-12-17 Advanced Life Science Institute, Inc. Antibody directed against pro-gastrin releasing peptide, and use thereof
CA2739318A1 (en) 2008-08-07 2010-02-11 Mercia Pharma, Llc Immunotherapeutic compositions for the treatment of alzheimer's disease
US8283372B2 (en) 2009-07-02 2012-10-09 Tetralogic Pharmaceuticals Corp. 2-(1H-indol-3-ylmethyl)-pyrrolidine dimer as a SMAC mimetic
US8674064B2 (en) 2010-03-03 2014-03-18 Onkologix Ltd Immunogenic compositions against human progastrin peptides
CN101797382B (zh) * 2010-03-03 2013-11-20 戚胜美 抗人前胃液素多肽免疫组合物
GB201121571D0 (en) 2011-12-15 2012-01-25 Astrimmune Ltd Compounds and uses thereof
EP2999485B1 (en) * 2013-05-21 2018-01-31 Tyg Oncology Ltd. Gastrin peptide immunogenic composition
US12150978B2 (en) 2017-06-15 2024-11-26 Cancer Advances Inc. Compositions and methods for preventing tumors and cancer
EP3624841A4 (en) 2017-06-15 2021-01-27 Cancer Advances, Inc., COMPOSITIONS AND METHODS OF INDUCING HUMORAL AND CELLULAR IMMUNITIES AGAINST TUMORS AND CANCER
WO2022099128A1 (en) * 2020-11-06 2022-05-12 Cancer Advances Inc. Compositions and methods for enhancing t cell penetration of tumors and cancers

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4201770A (en) * 1973-05-07 1980-05-06 The Ohio State University Antigenic modification of polypeptides
US4691006A (en) * 1983-03-04 1987-09-01 Ohio State University Antigenic modification of polypeptides
US4384995A (en) * 1980-01-16 1983-05-24 The Ohio State University Antigenic modification of polypeptides
US4526716A (en) * 1981-11-20 1985-07-02 The Ohio State University Antigenic modification of polypeptides
US4069313A (en) * 1974-11-19 1978-01-17 Merck & Co., Inc. Water-in-oil adjuvant composition
US4894443A (en) * 1984-02-08 1990-01-16 Cetus Corporation Toxin conjugates
DK0380230T3 (da) * 1989-01-24 1995-01-16 Aphton Corp Immunogene sammensætninger mod gastrin-peptider
US5023077A (en) * 1989-01-24 1991-06-11 Aphton Corporation Immunogenic compositions and methods for the treatment and prevention of gastric and duodenal ulcer disease
US5120829A (en) * 1989-03-20 1992-06-09 La Jolla Cancer Research Foundation Hydrophobic attachment site for adhesion peptides
US5256542A (en) * 1992-03-09 1993-10-26 Tanox Biosystems, Inc. Selecting low frequency antigen-specific single B lymphocytes with correction for background noise

Also Published As

Publication number Publication date
AU1179795A (en) 1995-05-29
DE69417252D1 (de) 1999-04-22
JP3694893B2 (ja) 2005-09-14
US5468494A (en) 1995-11-21
GR3029791T3 (en) 1999-06-30
EP0728148B1 (en) 1999-03-17
JPH09505056A (ja) 1997-05-20
DE69417252T2 (de) 1999-07-08
DK0728148T3 (da) 1999-09-27
WO1995013297A2 (en) 1995-05-18
WO1995013297A3 (en) 1995-06-15
ATE177757T1 (de) 1999-04-15
EP0728148A1 (en) 1996-08-28

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