ES2133295T3 - Peptidos ciclicos y su uso. - Google Patents

Peptidos ciclicos y su uso.

Info

Publication number
ES2133295T3
ES2133295T3 ES92117182T ES92117182T ES2133295T3 ES 2133295 T3 ES2133295 T3 ES 2133295T3 ES 92117182 T ES92117182 T ES 92117182T ES 92117182 T ES92117182 T ES 92117182T ES 2133295 T3 ES2133295 T3 ES 2133295T3
Authority
ES
Spain
Prior art keywords
amino acid
acid waste
waste
formula
cyclic peptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92117182T
Other languages
English (en)
Inventor
Mitsuhiro Wakimasu
Takashi Kikuchi
Akira Kawada
Hideo Shirahuji
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP4216019A external-priority patent/JP2677489B2/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ES2133295T3 publication Critical patent/ES2133295T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57536—Endothelin, vasoactive intestinal contractor [VIC]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

SE PRESENTAN (1) UN HEXAPEPTIDO CICLICO REPRESENTADO POR LA FORMULA [I] O UNA SAL DEL MISMO: EN DONDE X E Y REPRESENTAN CADA UNA RESIDUOS O-AMINOACIDOS. A REPRESENTA UN RESIDUO D-O-AMINOACIDO ACIDICO, B REPRESENTA UN RESIDUO O-AMINOACIDO NEUTRO, C REPRESENTA UN RESIDUO L-OAMINOACIDO Y D REPRESENTA UN RESIDUO D-O-AMINOACIDO QUE TIENE UN GRUPO DE ANILLO AROMATICO; Y (2) UNA COMPOSICION FARMACEUTICA QUE CONTIENE EL PEPTIDO REPRESENTADO POR LA FORMULA [I] O UNA SAL FARMACEUTICAMENTE ACEPTABLE DEL MISMO COMO INGREDIENTE ACTIVO.
ES92117182T 1991-11-19 1992-10-08 Peptidos ciclicos y su uso. Expired - Lifetime ES2133295T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP30363591 1991-11-19
JP3543692 1992-02-21
JP11179292 1992-04-30
JP4216019A JP2677489B2 (ja) 1991-08-13 1992-08-13 環状ペプチドおよびその用途

Publications (1)

Publication Number Publication Date
ES2133295T3 true ES2133295T3 (es) 1999-09-16

Family

ID=27460094

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92117182T Expired - Lifetime ES2133295T3 (es) 1991-11-19 1992-10-08 Peptidos ciclicos y su uso.

Country Status (3)

Country Link
EP (1) EP0552417B1 (es)
ES (1) ES2133295T3 (es)
GR (1) GR3031296T3 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2135151A1 (en) * 1993-11-08 1995-05-09 Mitsuhiro Wakimasu Cyclic hexapeptides, their production and use
EP0714909A1 (en) * 1994-12-01 1996-06-05 Takeda Chemical Industries, Ltd. Composition for prophylaxis or treatment of pulmonary circulatory diseases
US6251861B1 (en) * 1996-06-27 2001-06-26 Takeda Chemical Industries, Ltd. Treatment of cerebral infarction using cyclic hexapeptides
DK1165613T3 (da) 1999-03-29 2008-08-25 Procter & Gamble Melanocortinreceptorligander
PL2118123T3 (pl) 2007-01-31 2016-06-30 Dana Farber Cancer Inst Inc Stabilizowane peptydy p53 i ich zastosowania
JP5631201B2 (ja) 2007-03-28 2014-11-26 プレジデント アンド フェローズ オブ ハーバード カレッジ ステッチングされたポリペプチド
GB2453589A (en) 2007-10-12 2009-04-15 King S College London Protease inhibition
KR102104762B1 (ko) 2010-08-13 2020-04-24 에일러론 테라퓨틱스 인코포레이티드 펩티도미메틱 거대고리
EP2768518A4 (en) 2011-10-18 2015-05-27 Aileron Therapeutics Inc PEPTIDOMIMETIC MACROCYCLES
RU2642299C2 (ru) 2012-02-15 2018-01-24 Эйлерон Терапьютикс, Инк. P53 пептидомиметические макроциклы
CA2864120A1 (en) 2012-02-15 2013-08-22 Aileron Therapeutics, Inc. Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
BR112015009470A2 (pt) 2012-11-01 2019-12-17 Aileron Therapeutics Inc aminoácidos dissubstituídos e seus métodos de preparação e uso
CN107106642B (zh) 2014-09-24 2021-02-26 艾瑞朗医疗公司 拟肽大环化合物及其制剂
EP3197478A4 (en) 2014-09-24 2018-05-30 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
JP2018516844A (ja) 2015-03-20 2018-06-28 エルロン・セラピューティクス・インコーポレイテッドＡｉｌｅｒｏｎ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． ペプチド模倣大環状分子およびその使用
EP3347372A4 (en) 2015-09-10 2019-09-04 Aileron Therapeutics, Inc. PEPTIDOMIMETIC MACROCYCLES AS MODULATORS OF MCL-1

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2032559C (en) * 1989-12-28 2001-11-06 Kiyofumi Ishikawa Endothelin antagonistic cyclic pentapeptides

Also Published As

Publication number Publication date
EP0552417A1 (en) 1993-07-28
GR3031296T3 (en) 1999-12-31
EP0552417B1 (en) 1999-07-07

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