ATE202931T1 - Taxanderivate enthaltende arzneizubereitungen - Google Patents

Taxanderivate enthaltende arzneizubereitungen

Info

Publication number
ATE202931T1
ATE202931T1 AT95918046T AT95918046T ATE202931T1 AT E202931 T1 ATE202931 T1 AT E202931T1 AT 95918046 T AT95918046 T AT 95918046T AT 95918046 T AT95918046 T AT 95918046T AT E202931 T1 ATE202931 T1 AT E202931T1
Authority
AT
Austria
Prior art keywords
preparations containing
medicinal preparations
taxan derivatives
derivatives
containing taxan
Prior art date
Application number
AT95918046T
Other languages
English (en)
Inventor
Manfred Durr
Joerg-Christian Hager
Armin Wendel
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Application granted granted Critical
Publication of ATE202931T1 publication Critical patent/ATE202931T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicinal Preparation (AREA)
AT95918046T 1994-04-25 1995-04-24 Taxanderivate enthaltende arzneizubereitungen ATE202931T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9404951A FR2718963B1 (fr) 1994-04-25 1994-04-25 Nouvelle composition pharmaceutique à base de taxoïdes.
PCT/FR1995/000532 WO1995028923A1 (fr) 1994-04-25 1995-04-24 Compositions pharmaceutiques a base de derives de la classe des taxanes

Publications (1)

Publication Number Publication Date
ATE202931T1 true ATE202931T1 (de) 2001-07-15

Family

ID=9462475

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95918046T ATE202931T1 (de) 1994-04-25 1995-04-24 Taxanderivate enthaltende arzneizubereitungen

Country Status (26)

Country Link
US (1) US5670536A (de)
EP (1) EP0758231B1 (de)
JP (1) JP3950993B2 (de)
KR (1) KR100401119B1 (de)
CN (1) CN1283243C (de)
AT (1) ATE202931T1 (de)
AU (1) AU691283B2 (de)
BR (1) BR9507846A (de)
CZ (1) CZ285720B6 (de)
DE (1) DE69521693T2 (de)
DK (1) DK0758231T3 (de)
ES (1) ES2160163T3 (de)
FI (1) FI118204B (de)
FR (1) FR2718963B1 (de)
GE (1) GEP20002069B (de)
GR (1) GR3036211T3 (de)
HU (1) HU225971B1 (de)
NO (1) NO314745B1 (de)
NZ (1) NZ285122A (de)
PL (1) PL179623B1 (de)
PT (1) PT758231E (de)
RU (1) RU2157200C2 (de)
SK (1) SK283255B6 (de)
TW (1) TW416849B (de)
WO (1) WO1995028923A1 (de)
ZA (1) ZA953358B (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2698871B1 (fr) 1992-12-09 1995-02-24 Rhone Poulenc Rorer Sa Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
WO1999000113A1 (en) * 1997-06-27 1999-01-07 Vivorx Pharmaceuticals, Inc. Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
US6096331A (en) * 1993-02-22 2000-08-01 Vivorx Pharmaceuticals, Inc. Methods and compositions useful for administration of chemotherapeutic agents
US5439686A (en) * 1993-02-22 1995-08-08 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor
US6395770B1 (en) * 1995-10-26 2002-05-28 Baker Norton Pharmaceuticals, Inc. Method and compositions for administering taxanes orally to human patients
US6245805B1 (en) * 1995-10-26 2001-06-12 Baker Norton Pharmaceuticals, Inc. Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents
US8853260B2 (en) 1997-06-27 2014-10-07 Abraxis Bioscience, Llc Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
KR20080016756A (ko) * 1998-02-05 2008-02-21 노파르티스 아게 유기화합물 함유 조성물
US6071952A (en) * 1998-12-02 2000-06-06 Mylan Pharmaceuticals, Inc. Stabilized injectable pharmaceutical compositions containing taxoid anti-neoplastic agents
GB9920548D0 (en) * 1999-08-31 1999-11-03 Rhone Poulenc Rorer Sa Treatment of hepatocellular carcinoma
RU2213746C1 (ru) * 2002-02-15 2003-10-10 Научно-исследовательский институт физико-химической медицины Компонент, обеспечивающий поверхностно-активные свойства композиций - аналогов препаратов для заместительной сурфактантной терапии легочных заболеваний
DE10255285A1 (de) * 2002-11-26 2004-06-03 Mcs Micro Carrier Systems Gmbh Selbst formende Phospholipid-Gele
US20050152979A1 (en) * 2003-09-05 2005-07-14 Cell Therapeutics, Inc. Hydrophobic drug compositions containing reconstitution enhancer
US8557861B2 (en) * 2004-09-28 2013-10-15 Mast Therapeutics, Inc. Low oil emulsion compositions for delivering taxoids and other insoluble drugs
US7446126B2 (en) * 2004-10-08 2008-11-04 Indena S.P.A. Semisynthesis process for the preparation of 10-deacetyl-N-debenzoyl-paclitaxel
TWI376239B (en) * 2006-02-01 2012-11-11 Andrew Xian Chen Vitamin e succinate stabilized pharmaceutical compositions, methods for the preparation and the use thereof
US20080262078A1 (en) * 2007-04-20 2008-10-23 Namdeo Alok B Pharmaceutical Compositions
EP1987813A1 (de) * 2007-05-04 2008-11-05 Pharmatex Italia Srl Injizierbare pharmazeutische Formulierung aus Taxoiden in stabilen Liposomen
RU2370261C2 (ru) * 2007-08-03 2009-10-20 Закрытое Акционерное Общество "Биокад" Стабильная эмульсия для парентерального введения плохо растворимых в воде соединений, обладающих противоопухолевой активностью, и способ ее получения
WO2009047794A2 (en) * 2007-10-01 2009-04-16 Intas Pharmaceuticals Limited Taxane derivative composition
CN101971189A (zh) * 2007-11-07 2011-02-09 爱墨菲特有限公司 压痕泡沫数字扫描仪
RU2370258C2 (ru) * 2007-11-16 2009-10-20 Закрытое Акционерное Общество "Биокад" Фармацевтическая композиция для парентеральной доставки в форме лиофилизата и способ ее получения
ES2344674B1 (es) * 2008-08-07 2011-06-29 Gp Pharm, S.A. Composicion farmaceutica inyectable de taxanos.
US8541360B2 (en) * 2008-11-19 2013-09-24 Ben Venue Laboratories, Inc. Parenteral formulations comprising sugar-based esters and ethers
WO2012156999A1 (en) * 2011-05-19 2012-11-22 Manu Chaudhary Ready to use docetaxel formulation
CN108158991A (zh) 2012-07-19 2018-06-15 富士胶片株式会社 含紫杉烷系活性成分的液体组合物、其制造方法及液体制剂
EA022182B1 (ru) * 2012-12-24 2015-11-30 Общество С Ограниченной Ответственностью "Технология Лекарств" Способ получения липосомальной формы доцетаксела

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4534899A (en) * 1981-07-20 1985-08-13 Lipid Specialties, Inc. Synthetic phospholipid compounds
US4507217A (en) * 1983-03-07 1985-03-26 Lipid Specialties, Inc. Magnetic compositions and magnetic memory devices prepared therefrom
US5411947A (en) * 1989-06-28 1995-05-02 Vestar, Inc. Method of converting a drug to an orally available form by covalently bonding a lipid to the drug
ATE194767T1 (de) * 1992-03-23 2000-08-15 Univ Georgetown In liposomen verkapseltes taxol und verwendungsverfahren
AU6833994A (en) * 1993-05-17 1994-12-12 Liposome Company, Inc., The Incorporation of taxol into liposomes and gels
WO1994026253A1 (en) * 1993-05-19 1994-11-24 The Liposome Company, Inc. Liposome having a multicomponent bilayer which contains a bioactive agent as an integral component of the bilayer
US5415869A (en) * 1993-11-12 1995-05-16 The Research Foundation Of State University Of New York Taxol formulation

Also Published As

Publication number Publication date
RU2157200C2 (ru) 2000-10-10
AU691283B2 (en) 1998-05-14
PL316942A1 (en) 1997-02-17
PL179623B1 (pl) 2000-10-31
DE69521693T2 (de) 2002-05-02
FI964285A0 (fi) 1996-10-24
FI964285L (fi) 1996-10-24
HU225971B1 (en) 2008-01-28
NZ285122A (en) 1998-06-26
TW416849B (en) 2001-01-01
AU2412695A (en) 1995-11-16
DE69521693D1 (de) 2001-08-16
FR2718963A1 (fr) 1995-10-27
CN1146722A (zh) 1997-04-02
GEP20002069B (en) 2000-05-10
CZ309396A3 (en) 1997-01-15
KR100401119B1 (ko) 2004-03-19
BR9507846A (pt) 1997-09-16
SK283255B6 (sk) 2003-04-01
ZA953358B (en) 1996-01-17
SK135696A3 (en) 1997-05-07
JPH09512261A (ja) 1997-12-09
EP0758231B1 (de) 2001-07-11
US5670536A (en) 1997-09-23
WO1995028923A1 (fr) 1995-11-02
NO314745B1 (no) 2003-05-19
KR970702033A (ko) 1997-05-13
JP3950993B2 (ja) 2007-08-01
CZ285720B6 (cs) 1999-10-13
ES2160163T3 (es) 2001-11-01
NO964433D0 (no) 1996-10-18
NO964433L (no) 1996-10-18
HU9602942D0 (en) 1996-12-30
GR3036211T3 (en) 2001-10-31
CN1283243C (zh) 2006-11-08
DK0758231T3 (da) 2001-09-24
FR2718963B1 (fr) 1996-05-24
PT758231E (pt) 2001-11-30
EP0758231A1 (de) 1997-02-19
FI118204B (fi) 2007-08-31
HUT75513A (en) 1997-05-28

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Date Code Title Description
UEP Publication of translation of european patent specification