ES2136725T3 - Utilizacion de 2-amino-6-n-propil-amino-4,5,6,7-tetrahidrobenzotiazol (pramipexol) como medicamento con efecto antidepresivo. - Google Patents

Utilizacion de 2-amino-6-n-propil-amino-4,5,6,7-tetrahidrobenzotiazol (pramipexol) como medicamento con efecto antidepresivo.

Info

Publication number
ES2136725T3
ES2136725T3 ES94902661T ES94902661T ES2136725T3 ES 2136725 T3 ES2136725 T3 ES 2136725T3 ES 94902661 T ES94902661 T ES 94902661T ES 94902661 T ES94902661 T ES 94902661T ES 2136725 T3 ES2136725 T3 ES 2136725T3
Authority
ES
Spain
Prior art keywords
amino
pramipexol
tetrahidrobenzotiazole
propil
antidepressive effect
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94902661T
Other languages
English (en)
Inventor
Rudolf Hammer
Joachim Mierau
Erich Lehr
Franco Borsini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Boehringer Ingelheim Pharmaceuticals Inc
Original Assignee
Boehringer Ingelheim Pharma GmbH and Co KG
Boehringer Ingelheim Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma GmbH and Co KG, Boehringer Ingelheim Pharmaceuticals Inc filed Critical Boehringer Ingelheim Pharma GmbH and Co KG
Application granted granted Critical
Publication of ES2136725T3 publication Critical patent/ES2136725T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

LA INVENCION SE REFIERE A LA UTILIZACION DE PRAMIPEXOL COMO MEDICAMENTO CON EFECTO ANTIDEPRESIVO.
ES94902661T 1992-12-05 1993-12-02 Utilizacion de 2-amino-6-n-propil-amino-4,5,6,7-tetrahidrobenzotiazol (pramipexol) como medicamento con efecto antidepresivo. Expired - Lifetime ES2136725T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4241013A DE4241013A1 (de) 1992-12-05 1992-12-05 Verwendung von 2-Amino-6-n-propyl-amino-4,5,6,7-tetrahydrobenzothiazol als Arzneimittel mit antidepressiver Wirkung
PCT/EP1993/003389 WO1994013287A1 (de) 1992-12-05 1993-12-02 Verwendung von 2-amino-6-a-propyl-amino-4,5,6,7-tetrahydrobenzothiazol (pramipexol) als arzneimittel mit antidepressiver wirkung

Publications (1)

Publication Number Publication Date
ES2136725T3 true ES2136725T3 (es) 1999-12-01

Family

ID=6474503

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94902661T Expired - Lifetime ES2136725T3 (es) 1992-12-05 1993-12-02 Utilizacion de 2-amino-6-n-propil-amino-4,5,6,7-tetrahidrobenzotiazol (pramipexol) como medicamento con efecto antidepresivo.

Country Status (28)

Country Link
US (1) US6191153B1 (es)
EP (1) EP0675717B1 (es)
JP (1) JP3221880B2 (es)
KR (1) KR100311165B1 (es)
CN (1) CN1052400C (es)
AT (1) ATE183091T1 (es)
AU (1) AU674378B2 (es)
BG (1) BG62475B1 (es)
CA (1) CA2150131C (es)
CZ (1) CZ282679B6 (es)
DE (2) DE4241013A1 (es)
DK (1) DK0675717T3 (es)
ES (1) ES2136725T3 (es)
FI (1) FI952734L (es)
GR (1) GR3031521T3 (es)
HU (1) HU221014B1 (es)
IL (1) IL107870A (es)
MX (1) MX9307644A (es)
NO (1) NO306930B1 (es)
NZ (1) NZ258876A (es)
PL (1) PL309282A1 (es)
RU (1) RU2157685C2 (es)
SG (1) SG49228A1 (es)
SK (1) SK281441B6 (es)
TW (1) TW362973B (es)
UA (1) UA35604C2 (es)
WO (1) WO1994013287A1 (es)
ZA (1) ZA939065B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5650420A (en) * 1994-12-15 1997-07-22 Pharmacia & Upjohn Company Pramipexole as a neuroprotective agent
US6156777A (en) 1994-12-15 2000-12-05 Pharmacia & Upjohn Company Use of pramipexole as a neuroprotective agent
US6001861A (en) 1998-01-16 1999-12-14 Pharmacia & Upjohn Company Use of pramipexole in the treatment of restless legs syndrome
DE19830201A1 (de) * 1998-07-07 2000-01-13 Boehringer Ingelheim Pharma Mittel mit antidepressiver Wirkung
CA2301899C (en) * 1998-07-27 2008-11-18 Boehringer Ingelheim Pharma Kg Agent with an antidepressant activity
PE20011074A1 (es) 2000-02-23 2001-10-04 Upjohn Co Uso de pramipexol en el tratamiento de trastornos de adiccion
AU7887501A (en) * 2000-07-06 2002-01-21 Us Gov Health & Human Serv Tetrahydrobenzothiazole analogues as neuroprotective agents
US20020165246A1 (en) * 2001-03-05 2002-11-07 Andrew Holman Administration of sleep restorative agents
EP1260221A3 (en) * 2001-05-23 2002-12-18 Pfizer Products Inc. Combination treatment for depression and anxiety
DE10138275A1 (de) * 2001-08-10 2003-02-27 Boehringer Ingelheim Pharma Verbindungen zur Beseitigung der Anhedonie
US6727247B2 (en) * 2001-12-10 2004-04-27 Hoffman-La Roche Inc. Substituted benzothiazole amide derivatives
PA8578501A1 (es) * 2002-07-25 2005-02-04 Pharmacia Corp Forma de dosificacion una vez al dia de pramipexol
GB2394951A (en) * 2002-11-04 2004-05-12 Cipla Ltd One pot synthesis of 2,6-diamino-4,5,6,7-tetrahydro-benzothiazole
DE102004006808A1 (de) * 2004-02-11 2005-09-01 Grünenthal GmbH Substituierte 4,5,6,7-Tetrahydro-benzothiazol-2-ylamin-Verbindungen
CN101022788B (zh) * 2004-08-13 2010-11-10 贝林格尔·英格海姆国际有限公司 包含普拉克索或其可药用盐的延长释放小球制剂、其制备方法及其用途
UA93608C2 (ru) * 2004-08-13 2011-02-25 Берингер Ингельхайм Интернациональ Гмбх композициЯ таблетки пролонгированного высвобождения, которая содержит прамипексол или его фармацевтически приемлемую соль, СПОСОБ EE ИЗГОТОВЛЕНИЯ И EE ПРИМЕНЕНИЕ
RU2413510C2 (ru) * 2005-04-04 2011-03-10 Такеда Фармасьютикал Компани Лимитед Профилактический или терапевтический агент против депрессии или тревожного расстройства
EP1940398A1 (de) * 2005-10-18 2008-07-09 Boehringer Ingelheim International GmbH Verwendung von pramipexol zur behandlung des moderaten bis schweren restless legs syndroms (rls)
WO2007090883A1 (en) * 2006-02-10 2007-08-16 Boehringer Ingelheim International Gmbh Extended release formulation
EP1988875A2 (en) * 2006-02-10 2008-11-12 Boehringer Ingelheim International GmbH Modified release formulation
IL312486B2 (en) * 2017-04-10 2025-05-01 Chase Therapeutics Corp NK1 antagonist combination and method for treating synucleinopathies
CA3104811C (en) * 2017-06-30 2024-05-28 Chase Therapeutics Corporation Composition comprising pramipexole and nk1-antagonists for treating depression
TWI672472B (zh) * 2018-08-15 2019-09-21 鄭映芳 飲料製冰機裝置
CN110028464B (zh) * 2019-04-26 2022-11-18 浙江海洋大学 一种南极真菌次级代谢衍生物BTZ-one及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3572485D1 (en) * 1984-12-22 1989-09-28 Thomae Gmbh Dr K Tetrahydro-benzothiazoles, their production and their use as intermediates or drugs
DE3843227A1 (de) * 1988-12-22 1990-07-05 Boehringer Ingelheim Kg Neue verwendung von 2-amino-6-n-propylamino-4,5,6,7-tetrahydrobenzthiazol
DE3930282A1 (de) * 1989-09-11 1991-03-21 Boehringer Ingelheim Kg Verwendung von dopamin-autorezeptor-agonisten bei der behandlung von drogenabhaengigkeit

Also Published As

Publication number Publication date
KR950703953A (ko) 1995-11-17
CN1091635A (zh) 1994-09-07
HUT71798A (en) 1996-02-28
KR100311165B1 (ko) 2001-12-28
CA2150131C (en) 2004-09-21
TW362973B (en) 1999-07-01
CA2150131A1 (en) 1994-06-23
RU2157685C2 (ru) 2000-10-20
HK1019003A1 (en) 2000-01-14
IL107870A0 (en) 1994-04-12
ATE183091T1 (de) 1999-08-15
IL107870A (en) 1996-12-05
CN1052400C (zh) 2000-05-17
GR3031521T3 (en) 2000-01-31
UA35604C2 (uk) 2001-04-16
EP0675717A1 (de) 1995-10-11
BG62475B1 (bg) 1999-12-30
EP0675717B1 (de) 1999-08-11
FI952734A7 (fi) 1995-06-05
HU9501623D0 (en) 1995-08-28
NO952207D0 (no) 1995-06-02
HU221014B1 (hu) 2002-07-29
JP3221880B2 (ja) 2001-10-22
NZ258876A (en) 1997-07-27
DE4241013A1 (de) 1994-06-09
JPH08504201A (ja) 1996-05-07
CZ144095A3 (en) 1996-03-13
DK0675717T3 (da) 2000-02-28
US6191153B1 (en) 2001-02-20
SK74095A3 (en) 1996-05-08
AU5715294A (en) 1994-07-04
ZA939065B (en) 1994-08-04
PL309282A1 (en) 1995-10-02
DE59309733D1 (de) 1999-09-16
WO1994013287A1 (de) 1994-06-23
SG49228A1 (en) 1998-05-18
MX9307644A (es) 1994-06-30
AU674378B2 (en) 1996-12-19
NO306930B1 (no) 2000-01-17
CZ282679B6 (cs) 1997-08-13
FI952734A0 (fi) 1995-06-05
NO952207L (no) 1995-06-02
SK281441B6 (sk) 2001-03-12
BG99700A (bg) 1996-04-30
FI952734L (fi) 1995-06-05

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