ES2138199T3 - Trihidrato de lobaplatino. - Google Patents

Trihidrato de lobaplatino.

Info

Publication number
ES2138199T3
ES2138199T3 ES95915838T ES95915838T ES2138199T3 ES 2138199 T3 ES2138199 T3 ES 2138199T3 ES 95915838 T ES95915838 T ES 95915838T ES 95915838 T ES95915838 T ES 95915838T ES 2138199 T3 ES2138199 T3 ES 2138199T3
Authority
ES
Spain
Prior art keywords
trihydrate
lobaplatino
cyclobutanebis
methylamine
lactate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95915838T
Other languages
English (en)
Inventor
Eckhard Gunther
Jens-Peter Wulf
Jurgen Engel
Bernhard Kutscher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asta Medica GmbH
Original Assignee
Asta Medica GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica GmbH filed Critical Asta Medica GmbH
Application granted granted Critical
Publication of ES2138199T3 publication Critical patent/ES2138199T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

EL TRIHIDRATO DE LOBAPLATINO ES UNA FORMA NUEVA Y VENTAJOSA DE UN COMPLEJO DE PLATINO CON ACCION ANTITUMORAL.
ES95915838T 1994-04-15 1995-03-31 Trihidrato de lobaplatino. Expired - Lifetime ES2138199T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4415263A DE4415263C1 (de) 1994-04-15 1994-04-15 Cis-[trans-1,2-Cyclobutanbis(methylamin)-N,N']-[(2S)-lactato-O·1·, O·2·]-platin(II)-trihydrat (Lobaplatin-Trihydrat), seine Herstellung und arzneiliche Verwendung

Publications (1)

Publication Number Publication Date
ES2138199T3 true ES2138199T3 (es) 2000-01-01

Family

ID=6516957

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95915838T Expired - Lifetime ES2138199T3 (es) 1994-04-15 1995-03-31 Trihidrato de lobaplatino.

Country Status (14)

Country Link
US (1) US5747534A (es)
EP (1) EP0755399B1 (es)
JP (1) JP3579423B2 (es)
CN (1) CN1041094C (es)
AT (1) ATE185142T1 (es)
AU (1) AU2256195A (es)
DE (2) DE4415263C1 (es)
DK (1) DK0755399T3 (es)
ES (1) ES2138199T3 (es)
GR (1) GR3032061T3 (es)
IL (1) IL113360A (es)
TW (1) TW367329B (es)
WO (1) WO1995028407A1 (es)
ZA (1) ZA953095B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100314720B1 (ko) * 1999-03-26 2001-11-26 박호군 포스파젠 삼합체에 도입된 백금 착물, 그의 제조방법 및 그를 유효성분으로 하는 항암제
CA2385528C (en) 1999-10-01 2013-12-10 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
CN102020679B (zh) * 2010-11-24 2013-12-25 贵州益佰制药股份有限公司 一种以草酸盐制备洛铂三水合物的方法
CN103467528B (zh) * 2013-08-21 2016-06-08 江苏奥赛康药业股份有限公司 一种洛铂的制备方法
IL296691B2 (en) 2014-04-25 2023-11-01 2Seventy Bio Inc MND promoter chimeric antigen receptors
EP3738597A1 (en) 2014-04-25 2020-11-18 Bluebird Bio, Inc. Improved methods for manufacturing adoptive cell therapies
CN106793780B (zh) 2014-06-06 2020-05-26 蓝鸟生物公司 改善的t细胞组合物
CN105218587B (zh) * 2014-06-20 2018-08-14 贵州益佰制药股份有限公司 一种洛铂晶体、制备方法及药物应用
JP6404461B2 (ja) * 2014-06-20 2018-10-10 貴州益佰制葯股▲ふん▼有限公司 ロバプラチン結晶体、調製方法及び薬物応用
CN105330702B (zh) * 2014-06-20 2018-08-14 贵州益佰制药股份有限公司 一种洛铂晶体、制备方法及药物应用
CN105198932B (zh) * 2014-06-20 2018-09-21 贵州益佰制药股份有限公司 洛铂二水合物、制备方法及药物应用
MX2017001079A (es) 2014-07-24 2017-09-12 Bluebird Bio Inc Receptores de antígeno quiméricos de antígeno de maduración de células b (bcma).
EP3971210A1 (en) 2014-12-12 2022-03-23 2seventy bio, Inc. Composition for use in the treatment of b cell related conditions in a subject in need thereof comprisine an effector cell comrising a bcma chimeric antigen receptors
WO2017099712A1 (en) 2015-12-07 2017-06-15 Bluebird Bio, Inc. Improved t cell compositions
KR20240005168A (ko) 2016-11-04 2024-01-11 2세븐티 바이오, 인코포레이티드 항-bcma car t 세포 조성물
CN111721843B (zh) * 2019-03-19 2022-05-17 海南长安国际制药有限公司 与洛铂有关物质的检测方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7807334A (nl) * 1978-07-06 1980-01-08 Tno Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een genees- middel met toepassing van een dergelijk platina-dia- minecomplex voor de behandeling van kanker, alsmede al- dus verkregen gevormd geneesmiddel.
SU1186617A1 (ru) * 1980-01-03 1985-10-23 Нидерландзе Сентрале Организати Фор Тегепаст-Натурветеншаппелийк Ондерцоек (Фирма) Платино ( @ )-диаминовые комплексы,про вл ющие противоопухолевую активность
NL181434C (nl) * 1980-01-03 1987-08-17 Tno Platina(iv)-diamine-complexen, alsmede hun bereiding en toepassing.
US4912100A (en) * 1986-10-15 1990-03-27 Toray Industries, Inc. Platinum complex, process for preparing same and antitumor agent
DE3843571A1 (de) * 1988-01-09 1989-07-20 Asta Pharma Ag 1,2-bis(aminomethyl)cyclobutan-platin-komplexe
JPH02275891A (ja) * 1988-12-29 1990-11-09 Tsumura & Co 新規な複核白金錯体および該錯体を有効成分とする抗腫瘍剤
DE4115559A1 (de) * 1990-05-15 1991-11-21 Deutsches Krebsforsch Antitumormittel mit verminderter toxizitaet auf der basis von cytostatika und xanthogenaten

Also Published As

Publication number Publication date
JPH09511991A (ja) 1997-12-02
DK0755399T3 (da) 2000-03-27
ZA953095B (en) 1996-01-05
CN1041094C (zh) 1998-12-09
WO1995028407A1 (de) 1995-10-26
IL113360A0 (en) 1995-07-31
US5747534A (en) 1998-05-05
EP0755399B1 (de) 1999-09-29
DE4415263C1 (de) 1995-11-30
ATE185142T1 (de) 1999-10-15
GR3032061T3 (en) 2000-03-31
EP0755399A1 (de) 1997-01-29
JP3579423B2 (ja) 2004-10-20
DE59506958D1 (de) 1999-11-04
IL113360A (en) 1999-09-22
AU2256195A (en) 1995-11-10
TW367329B (en) 1999-08-21
CN1120046A (zh) 1996-04-10

Similar Documents

Publication Publication Date Title
DK0755399T3 (da) Lobaplatin-trihydrat
ES2054778T3 (es) Complejos de 1,2-bis (aminometil) ciclobutano-platino.
FI950374A0 (fi) Glykopeptidiantibioottijohdannaisia
DE68918441D1 (de) Auslasspumpe.
TR28384A (tr) Flüoroalifatik -ve karboksil- iceren terminal gruplarina sahip polisilokzanlar, bunlarin hazirlanmasi, ve lifli malzemelerin muamelesinde kullanimlari.
DE69008605D1 (de) Pumpvorrichtung.
TR199501316A2 (tr) Sikistirilmis karma hava-pompasi.
RU95101375A (ru) Производные n-(3-аминопропил)-n-фенил-5,6,7,8-тетрагидронафталин-2-карбоксамида, их получение и применение в терапии
DE69021563D1 (de) Gasmischvorrichtung.
PH24452A (en) (2,2-bis(aminomethyl 1,3,propanediol-n,n)platinum complexes
EP0646589A3 (en) Anti-tumor platinum (IV) complexes.
IT1243193B (it) Composizioni farmaceutiche orali a base di melatonina
FI893616L (fi) Ny anvaendning foer 5-hetero-aryl- eller 5-arylsubstituerade imidazo/2,1-a/ isokinoliner.
DE68919995D1 (de) Sicherheitshandapparat.
EA200000875A1 (ru) Белки, взаимодействующие с каспазой-8
DE68922983D1 (de) Härtbare, mit Silikon beschichtete Dichtung.
FI944563A0 (fi) Mikro-organismeja, valmistusmenetelmä ja käyttö
ZA891242B (en) 24r-scymnol,and preparation and use thereof
EA200000163A1 (ru) Противоопухолевое средство
TR25566A (tr) Katalizör bilesimleri ve polimerizasyon islemi heksakisfosfinler ve heksahalo bilesikler.
DE3680458D1 (de) Kolben und zylinderanordnung.
NO913108L (no) Nytt platina (ii) kompleks og middel for behandling av malign tumor.
DE59005057D1 (de) Mischgaspumpen-Antrieb.
DE3773723D1 (de) Gasverdichter.
DE68904322D1 (de) Einrichtung zur behandlung von gasen.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 755399

Country of ref document: ES