ES2138997T3 - Receptores del snc humanos que se unen a cainato de la familia eaa3. - Google Patents

Receptores del snc humanos que se unen a cainato de la familia eaa3.

Info

Publication number
ES2138997T3
ES2138997T3 ES93309956T ES93309956T ES2138997T3 ES 2138997 T3 ES2138997 T3 ES 2138997T3 ES 93309956 T ES93309956 T ES 93309956T ES 93309956 T ES93309956 T ES 93309956T ES 2138997 T3 ES2138997 T3 ES 2138997T3
Authority
ES
Spain
Prior art keywords
family
caain
eaa3
joining
eaa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93309956T
Other languages
English (en)
Inventor
Rajender Kamboj
Candace E Elliott
Stephen L Nutt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allelix Biopharmaceuticals Inc
Original Assignee
Allelix Biopharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allelix Biopharmaceuticals Inc filed Critical Allelix Biopharmaceuticals Inc
Application granted granted Critical
Publication of ES2138997T3 publication Critical patent/ES2138997T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Battery Electrode And Active Subsutance (AREA)
  • Prostheses (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Secondary Cells (AREA)

Abstract

LA NUEROTRANSMISION MEDIANTE LOS AMINOACIDOS EXCITATORIOS (EAAS) TALES COMO EL GLUTAMATO ES INTERMEDIADA POR MEDIOS DE LOS RECEPTORES SUPERFICIALES QUE SE UNEN A LA MEMBRANA. ACTUALMENTE SE HA AISLADO EL DNA QUE CODIFICA UNA FAMILIA DEL TIPO QUE SE UNE AL KAINATO DEL RECEPTOR EAA Y SE HA CARACTERIZADO LA PROTEINA RECEPTORA. AQUI SE DESCRIBEN LINEAS CELULARES RECOMBINANTES QUE PRODUCEN EL RECEPTOR EAA COMO PRODUCTO HETEROLOGO QUE SE UNE A LA MEMBRANA. TAMBIEN SE DESCRIBEN ASPECTOS RELACIONADOS DE LA INVENCION, QUE SON DE SIGNIFICACION COMERCIAL. SE INCLUYE EL USO DE LAS LINEAS CELULARES COMO HERRAMIENTA PARA DESCUBRIR COMPUESTOS QUE MODULEN LA ESTIMULACION DEL RECEPTOR EAA.
ES93309956T 1992-12-11 1993-12-10 Receptores del snc humanos que se unen a cainato de la familia eaa3. Expired - Lifetime ES2138997T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US98979392A 1992-12-11 1992-12-11

Publications (1)

Publication Number Publication Date
ES2138997T3 true ES2138997T3 (es) 2000-02-01

Family

ID=25535462

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93309956T Expired - Lifetime ES2138997T3 (es) 1992-12-11 1993-12-10 Receptores del snc humanos que se unen a cainato de la familia eaa3.

Country Status (10)

Country Link
US (3) US6500624B1 (es)
EP (1) EP0617123B1 (es)
JP (1) JP3361591B2 (es)
AT (1) ATE184051T1 (es)
CA (1) CA2110933C (es)
DE (1) DE69326228T2 (es)
DK (1) DK0617123T3 (es)
ES (1) ES2138997T3 (es)
GR (1) GR3031983T3 (es)
MX (1) MX9307841A (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2110933C (en) * 1992-12-11 2005-02-08 Rajender Kamboj Kainate-binding, human cns receptors of the eaa3 family
DE69434333T2 (de) * 1993-12-23 2006-03-09 Nps Allelix Corp., Mississauga Methoden unter verwendung von eaa3 oder eaa4 rezeptoren
DE4403666A1 (de) * 1994-02-07 1995-08-10 Basf Ag Untereinheiten von Glutamatrezeptoren, Verfahren zu ihrer Herstellung und ihre Verwendung
US6720311B2 (en) * 1997-12-18 2004-04-13 David Tsai Polypeptide for the treatment of cancer and a method for preparation thereof
EP1290025A2 (en) * 2000-03-24 2003-03-12 Bayer Aktiengesellschaft REGULATION OF HUMAN GluR5-LIKE RECEPTOR
AU2001283042A1 (en) * 2000-07-29 2002-02-13 Genaissance Pharmaceuticals, Inc. Haplotypes of the il12b gene

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991006648A1 (en) * 1989-10-27 1991-05-16 The Salk Institute For Biological Studies Glutamate receptor compositions and methods
PT529994E (pt) * 1991-08-26 2000-10-31 Nps Allelix Corp Receptor de ka-1 humano um receptor de cainato de elevada afinidade da familia eaa1 (aminoacido excitatorio)
DE69230872T2 (de) * 1991-08-27 2000-10-26 Allelix Biopharmaceuticals Inc., Mississauga Menschlicher KA-2-Rezeptor, Rezeptor aus der EAA2-Familie (Excitatory Amino Acid) mit hoher Affinität für Kainat
CA2110933C (en) * 1992-12-11 2005-02-08 Rajender Kamboj Kainate-binding, human cns receptors of the eaa3 family

Also Published As

Publication number Publication date
US6500624B1 (en) 2002-12-31
EP0617123A1 (en) 1994-09-28
CA2110933C (en) 2005-02-08
CA2110933A1 (en) 1994-06-12
EP0617123B1 (en) 1999-09-01
US6018023A (en) 2000-01-25
JPH06319550A (ja) 1994-11-22
MX9307841A (es) 1994-07-29
JP3361591B2 (ja) 2003-01-07
GR3031983T3 (en) 2000-03-31
DE69326228T2 (de) 2000-02-03
ATE184051T1 (de) 1999-09-15
US5547855A (en) 1996-08-20
DK0617123T3 (da) 1999-12-13
DE69326228D1 (de) 1999-10-07

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