ES2140392T3 - Metodo y composicion para mejorar los efectos adversos del envejecimiento. - Google Patents
Metodo y composicion para mejorar los efectos adversos del envejecimiento.Info
- Publication number
- ES2140392T3 ES2140392T3 ES91912579T ES91912579T ES2140392T3 ES 2140392 T3 ES2140392 T3 ES 2140392T3 ES 91912579 T ES91912579 T ES 91912579T ES 91912579 T ES91912579 T ES 91912579T ES 2140392 T3 ES2140392 T3 ES 2140392T3
- Authority
- ES
- Spain
- Prior art keywords
- aging
- adverse effects
- cells
- improve
- kinetine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000002411 adverse Effects 0.000 title abstract 3
- 230000032683 aging Effects 0.000 title abstract 3
- 230000000694 effects Effects 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- -1 AMINO Chemical group 0.000 abstract 2
- 102000004127 Cytokines Human genes 0.000 abstract 2
- 108090000695 Cytokines Proteins 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 239000006071 cream Substances 0.000 abstract 1
- 230000002498 deadly effect Effects 0.000 abstract 1
- 230000018109 developmental process Effects 0.000 abstract 1
- 239000006210 lotion Substances 0.000 abstract 1
- 230000004660 morphological change Effects 0.000 abstract 1
- 239000002674 ointment Substances 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
- 238000002603 single-photon emission computed tomography Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/606—Nucleosides; Nucleotides; Nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Birds (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Stroboscope Apparatuses (AREA)
- Measuring Volume Flow (AREA)
- Ink Jet (AREA)
- Materials Applied To Surfaces To Minimize Adherence Of Mist Or Water (AREA)
- Tea And Coffee (AREA)
- Medicinal Preparation (AREA)
- Organic Insulating Materials (AREA)
- Road Signs Or Road Markings (AREA)
Abstract
SE HAN DESCUBIERTO CITOQUINAS DE 6-PURINA (DE AMINO SUSTITUIDO, QUE COMPRENDE QUINETINA PARA MEJORAR LOS EFECTOS ADVERSOS DEL ENVEJECIMIENTO DE LAS CELULAS DE LOS MAMIFEROS, RALENTIZANDO O INVIRTIENDO LOS CAMBIOS MORFOLOGICOS QUE ACOMPAÑAN NORMALMENTE AL ENVEJECIMIENTO DE DICHAS CELULAS, SIN AUMENTAR SIGNIFICATIVAMENTE EL NIVEL DE CRECIMIENTO O LA CAPACIDAD PROLIFERATIVA TOTAL DE DICHAS CELULAS. ASI SE PREVEN METODOS PARA CONTRAATACAR LOS EFECTOS ADVERSOS DEL ENVEJECIMIENTO DE LAS CELULAS EN CULTIVO E IN VIVO QUE COMPRENDEN LA ADMINISTRACION DE DICHAS CELULAS EN UNA CANTIDAD DE MEJORAMIENTO DE LOS EFECTOS ADVERSOS DEL ENVEJECIMIENTO DE QUINETINA U OTRA CITOQUINA DE 6-PURINA (AMINO SUSTITUIDA). SE PREVEN TAMBIEN COMPOSICIONES PARA LLEVAR A CABO LOS METODOS. ENTRE LAS APLICACIONES PREFERIDAS DE LA INVENCION ESTAN LA PRESERVACION DE LA SALUD DE LAS CELULAS DE LOS MAMIFEROS EN CULTIVO, POR APLICACION A LA PIEL HUMANA DE LOCIONES QUE CONTIENEN QUINETINA, UNGUENTOS O CREMAS, LA SALUD Y EL ASPECTODE JUVENTUD DE LA PIEL.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1991/003466 WO1992020341A1 (en) | 1991-05-16 | 1991-05-16 | Method and composition for ameliorating the adverse effects of aging |
| CA002108369A CA2108369C (en) | 1991-05-16 | 1991-05-16 | Method and composition for ameliorating the adverse effects of aging |
| NZ238210A NZ238210A (en) | 1991-05-21 | 1991-05-21 | Use of 6-(substituted amino) purine cytokinins for inhibiting effects of ageing on mammalian cells |
| IL9820491A IL98204A (en) | 1991-05-16 | 1991-05-21 | Cosmetic method and compositions for ameliorating the adverse effects of aging using 6-(substituted amino) purine cytokinins |
| CN91104472A CN1037235C (zh) | 1991-05-16 | 1991-06-28 | 6-(取代氨基)嘌呤促细胞分裂素在制备抗衰老组合物中的用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2140392T3 true ES2140392T3 (es) | 2000-03-01 |
| ES2140392T5 ES2140392T5 (es) | 2004-10-16 |
Family
ID=27508530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES91912579T Expired - Lifetime ES2140392T5 (es) | 1991-05-16 | 1991-05-16 | Metodo y composicion para mejorar los efectos adversos del envejecimiento. |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0584068B2 (es) |
| JP (1) | JP3103375B2 (es) |
| KR (1) | KR100196660B1 (es) |
| CN (1) | CN1037235C (es) |
| AT (1) | ATE185272T1 (es) |
| AU (1) | AU666836B2 (es) |
| BR (1) | BR9107307A (es) |
| CA (1) | CA2108369C (es) |
| DE (1) | DE69131692T3 (es) |
| DK (1) | DK0584068T4 (es) |
| ES (1) | ES2140392T5 (es) |
| FI (1) | FI111219B (es) |
| GR (1) | GR3032325T3 (es) |
| IL (1) | IL98204A (es) |
| IN (1) | IN172210B (es) |
| NO (1) | NO304814B1 (es) |
| NZ (1) | NZ247836A (es) |
| WO (1) | WO1992020341A1 (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001031549A (ja) * | 1999-07-14 | 2001-02-06 | Pola Chem Ind Inc | 真皮コラーゲン線維束再構築剤及びそれを含有する化粧料 |
| US20040117871A1 (en) * | 2000-11-25 | 2004-06-17 | Peter Meyer | Plant growth regulation |
| DE10100122A1 (de) * | 2001-01-03 | 2002-07-11 | Henkel Kgaa | Verfahren zur Bestimmung der Hautalterung in vitro |
| JP2002212052A (ja) * | 2001-01-15 | 2002-07-31 | Hajime Ito | 外用組成物 |
| ES2420104T3 (es) * | 2001-04-13 | 2013-08-22 | Otsuka Pharmaceutical Co., Ltd. | Promotores de la captación de azúcar |
| CZ294535B6 (cs) * | 2001-08-02 | 2005-01-12 | Ústav Experimentální Botaniky Avčr | Heterocyklické sloučeniny na bázi N6-substituovaného adeninu, způsoby jejich přípravy, jejich použití pro přípravu léčiv, kosmetických přípravků a růstových regulátorů, farmaceutické přípravky, kosmetické přípravky a růstové regulátory tyto sloučeniny obsahující |
| JP4567307B2 (ja) * | 2003-08-25 | 2010-10-20 | 株式会社ノエビア | 皮膚外用剤 |
| CN100493510C (zh) * | 2007-06-04 | 2009-06-03 | 西北农林科技大学 | 6-糠氨基嘌呤用于制备治疗心肌组织氧化损伤药物的应用 |
| CN100493506C (zh) * | 2007-06-04 | 2009-06-03 | 西北农林科技大学 | 化合物6-糠基氨基嘌呤在制备抗脑组织氧化损伤药物应用 |
| CN100493509C (zh) * | 2007-06-04 | 2009-06-03 | 西北农林科技大学 | 化合物6-糠基氨基嘌呤用于制备抗睾丸衰老药物的应用 |
| CN100493507C (zh) * | 2007-06-04 | 2009-06-03 | 西北农林科技大学 | 化合物6-糠基氨基嘌呤制备抗雌性生殖器官损伤药物应用 |
| CN100493508C (zh) * | 2007-06-04 | 2009-06-03 | 西北农林科技大学 | 化合物6-糠氨基嘌呤用于制备抗心肌缺血损伤药物的应用 |
| CZ302225B6 (cs) * | 2007-07-04 | 2010-12-29 | Univerzita Palackého v Olomouci | Substituované 6-anilinopurinové deriváty jako inhibitory cytokinin oxidasy a prípravky obsahující tyto slouceniny |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1587633A (es) † | 1968-07-04 | 1970-03-27 | ||
| DD148889A3 (de) * | 1974-08-19 | 1981-06-17 | Forsch Die Gaerungsindustrie E | Verfahren zur herstellung eiweissreicher hefen |
| JPS6019709A (ja) * | 1983-07-14 | 1985-01-31 | Tsunetaka Yokoyama | 皮膚の老化防止及細胞分裂促進の化粧品の製造方法 |
| DE3529497A1 (de) * | 1985-08-17 | 1987-02-26 | Boehringer Mannheim Gmbh | N(pfeil hoch)6(pfeil hoch)-disubstituierte purinderivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
| US5021422A (en) * | 1989-06-08 | 1991-06-04 | Senetek Plc | Method and composition for treating hyperproliferative skin diseases using 6-aminopurine cytokinins |
| JPH0619709A (ja) * | 1992-04-29 | 1994-01-28 | Sun Microsyst Inc | パイプラインプロセッサを有するコンピュータシステム |
-
1991
- 1991-05-16 WO PCT/US1991/003466 patent/WO1992020341A1/en not_active Ceased
- 1991-05-16 EP EP91912579A patent/EP0584068B2/en not_active Expired - Lifetime
- 1991-05-16 CA CA002108369A patent/CA2108369C/en not_active Expired - Lifetime
- 1991-05-16 ES ES91912579T patent/ES2140392T5/es not_active Expired - Lifetime
- 1991-05-16 KR KR1019930703452A patent/KR100196660B1/ko not_active Expired - Fee Related
- 1991-05-16 BR BR9107307A patent/BR9107307A/pt not_active IP Right Cessation
- 1991-05-16 DK DK91912579T patent/DK0584068T4/da active
- 1991-05-16 DE DE69131692T patent/DE69131692T3/de not_active Expired - Fee Related
- 1991-05-16 JP JP03512066A patent/JP3103375B2/ja not_active Expired - Fee Related
- 1991-05-16 AT AT91912579T patent/ATE185272T1/de not_active IP Right Cessation
- 1991-05-16 AU AU81884/91A patent/AU666836B2/en not_active Ceased
- 1991-05-21 NZ NZ247836A patent/NZ247836A/en not_active IP Right Cessation
- 1991-05-21 IL IL9820491A patent/IL98204A/en not_active IP Right Cessation
- 1991-05-29 IN IN409/MAS/91A patent/IN172210B/en unknown
- 1991-06-28 CN CN91104472A patent/CN1037235C/zh not_active Expired - Fee Related
-
1993
- 1993-11-15 FI FI935039A patent/FI111219B/fi active
- 1993-11-15 NO NO934115A patent/NO304814B1/no not_active IP Right Cessation
-
2000
- 2000-01-07 GR GR20000400023T patent/GR3032325T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0584068A1 (en) | 1994-03-02 |
| EP0584068A4 (es) | 1994-04-06 |
| CA2108369A1 (en) | 1992-11-17 |
| CA2108369C (en) | 2003-01-28 |
| WO1992020341A1 (en) | 1992-11-26 |
| DK0584068T3 (da) | 2000-04-10 |
| DE69131692D1 (de) | 1999-11-11 |
| NZ247836A (en) | 1997-03-24 |
| BR9107307A (pt) | 1994-06-14 |
| JP3103375B2 (ja) | 2000-10-30 |
| IL98204A (en) | 1994-11-11 |
| NO304814B1 (no) | 1999-02-22 |
| ATE185272T1 (de) | 1999-10-15 |
| CN1068033A (zh) | 1993-01-20 |
| FI935039L (fi) | 1993-11-15 |
| FI111219B (fi) | 2003-06-30 |
| CN1037235C (zh) | 1998-02-04 |
| AU666836B2 (en) | 1996-02-29 |
| FI935039A0 (fi) | 1993-11-15 |
| GR3032325T3 (en) | 2000-04-27 |
| DK0584068T4 (da) | 2004-06-14 |
| JPH10510240A (ja) | 1998-10-06 |
| EP0584068B1 (en) | 1999-10-06 |
| IN172210B (es) | 1993-05-01 |
| AU8188491A (en) | 1992-12-30 |
| NO934115L (no) | 1994-01-17 |
| KR100196660B1 (ko) | 1999-06-15 |
| ES2140392T5 (es) | 2004-10-16 |
| DE69131692T2 (de) | 2000-03-16 |
| DE69131692T3 (de) | 2004-09-23 |
| EP0584068B2 (en) | 2004-04-28 |
| NO934115D0 (no) | 1993-11-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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