ES2140922T3 - Benzoilguanidinas orto-sustituidas, procedimiento para su preparacion, su empleo como medicamento o agente de diagnostico, asi como medicamento que las contiene. - Google Patents
Benzoilguanidinas orto-sustituidas, procedimiento para su preparacion, su empleo como medicamento o agente de diagnostico, asi como medicamento que las contiene.Info
- Publication number
- ES2140922T3 ES2140922T3 ES97100777T ES97100777T ES2140922T3 ES 2140922 T3 ES2140922 T3 ES 2140922T3 ES 97100777 T ES97100777 T ES 97100777T ES 97100777 T ES97100777 T ES 97100777T ES 2140922 T3 ES2140922 T3 ES 2140922T3
- Authority
- ES
- Spain
- Prior art keywords
- medicinal product
- orto
- benzoilguanidines
- substituted
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229940126601 medicinal product Drugs 0.000 title 2
- 229940039227 diagnostic agent Drugs 0.000 title 1
- 239000000032 diagnostic agent Substances 0.000 title 1
- 206010002383 Angina Pectoris Diseases 0.000 abstract 1
- 230000003288 anthiarrhythmic effect Effects 0.000 abstract 1
- 239000003416 antiarrhythmic agent Substances 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000035778 pathophysiological process Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Reproductive Health (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
BENZOIL-GUANIDINAS SUSTITUIDAS EN POSICION ORTO DE FORMULA I EN DONDE R(2) Y R(3) TIENEN LOS SIGNIFICADOS DADOS EN LAS REIVINDICACIONES, SE UTILIZAN COMO MEDICAMENTOS ANTIARRITMICOS CON COMPONENTES CARDIOPROTECTORES PARA LA PREVENCION DEL INFARTO Y SU TRATAMIENTO ASI COMO PARA EL TRATAMIENTO DE LA ANGINA DE PECHO. INHIBEN TAMBIEN DE MANERA PREVENTIVA LOS PROCESOS PATOFISIOLOGICOS EN LA APARICION DE LESIONES INDUCIDAS ISQUEMICAMENTE, EN PARTICULAR EN LA APARICION DE ARRITMIAS CARDIACAS INDUCIDAS ISQUEMICAMENTE.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19606509A DE19606509A1 (de) | 1996-02-22 | 1996-02-22 | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2140922T3 true ES2140922T3 (es) | 2000-03-01 |
Family
ID=7786043
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES97100777T Expired - Lifetime ES2140922T3 (es) | 1996-02-22 | 1997-01-20 | Benzoilguanidinas orto-sustituidas, procedimiento para su preparacion, su empleo como medicamento o agente de diagnostico, asi como medicamento que las contiene. |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US5856574A (es) |
| EP (1) | EP0791577B1 (es) |
| JP (1) | JP3974677B2 (es) |
| KR (1) | KR100476796B1 (es) |
| CN (1) | CN1060764C (es) |
| AR (1) | AR005933A1 (es) |
| AT (1) | ATE186296T1 (es) |
| AU (1) | AU723096B2 (es) |
| BR (1) | BR9701046A (es) |
| CA (1) | CA2198176A1 (es) |
| CZ (1) | CZ287843B6 (es) |
| DE (2) | DE19606509A1 (es) |
| DK (1) | DK0791577T3 (es) |
| ES (1) | ES2140922T3 (es) |
| GR (1) | GR3032293T3 (es) |
| HR (1) | HRP970101B1 (es) |
| HU (1) | HUP9700502A3 (es) |
| ID (1) | ID16042A (es) |
| IL (1) | IL120259A (es) |
| MX (1) | MX9701323A (es) |
| MY (1) | MY117642A (es) |
| NO (1) | NO307046B1 (es) |
| NZ (1) | NZ314268A (es) |
| PL (1) | PL185752B1 (es) |
| RU (1) | RU2218329C2 (es) |
| SI (1) | SI0791577T1 (es) |
| SK (1) | SK281753B6 (es) |
| TR (1) | TR199700144A2 (es) |
| TW (1) | TW404937B (es) |
| ZA (1) | ZA971514B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19713427A1 (de) * | 1997-04-01 | 1998-10-08 | Hoechst Ag | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| CN111099959B (zh) * | 2019-12-30 | 2022-09-02 | 西安瑞联新材料股份有限公司 | 一种1,4-二溴-2,5-二碘苯的工业化生产方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ284456B6 (cs) * | 1992-02-15 | 1998-12-16 | Hoechst Aktiengesellschaft | Aminosubstituované benzoylguanidiny, způsob jejich přípravy, jejich použití jako léčiv a léčivo, které je obsahuje |
| ATE157351T1 (de) * | 1993-02-20 | 1997-09-15 | Hoechst Ag | Substituierte benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament, als inhibitoren des zellulären na+/h+-austauschs oder als diagnostikum sowie sie enthaltendes medikament |
| DE4328869A1 (de) * | 1993-08-27 | 1995-03-02 | Hoechst Ag | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE4422685A1 (de) * | 1994-06-29 | 1996-01-04 | Hoechst Ag | Ortho-amino-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE19517848A1 (de) * | 1995-05-16 | 1996-11-21 | Merck Patent Gmbh | Fluorhaltige Benzoylguanidine |
| US5596407A (en) * | 1995-06-07 | 1997-01-21 | Varian Associates, Inc | Optical detector for echelle spectrometer |
-
1996
- 1996-02-22 DE DE19606509A patent/DE19606509A1/de not_active Withdrawn
-
1997
- 1997-01-20 DE DE59700640T patent/DE59700640D1/de not_active Expired - Lifetime
- 1997-01-20 ES ES97100777T patent/ES2140922T3/es not_active Expired - Lifetime
- 1997-01-20 DK DK97100777T patent/DK0791577T3/da active
- 1997-01-20 EP EP97100777A patent/EP0791577B1/de not_active Expired - Lifetime
- 1997-01-20 SI SI9730024T patent/SI0791577T1/xx not_active IP Right Cessation
- 1997-01-20 AT AT97100777T patent/ATE186296T1/de not_active IP Right Cessation
- 1997-02-11 PL PL97318417A patent/PL185752B1/pl not_active IP Right Cessation
- 1997-02-19 NZ NZ314268A patent/NZ314268A/en unknown
- 1997-02-19 AU AU14773/97A patent/AU723096B2/en not_active Ceased
- 1997-02-20 AR ARP970100687A patent/AR005933A1/es active IP Right Grant
- 1997-02-20 IL IL12025997A patent/IL120259A/en not_active IP Right Cessation
- 1997-02-20 TW TW086101993A patent/TW404937B/zh not_active IP Right Cessation
- 1997-02-20 SK SK237-97A patent/SK281753B6/sk unknown
- 1997-02-20 TR TR97/00144A patent/TR199700144A2/xx unknown
- 1997-02-20 MY MYPI97000647A patent/MY117642A/en unknown
- 1997-02-20 CN CN97102493A patent/CN1060764C/zh not_active Expired - Fee Related
- 1997-02-20 CZ CZ1997528A patent/CZ287843B6/cs not_active IP Right Cessation
- 1997-02-21 MX MX9701323A patent/MX9701323A/es unknown
- 1997-02-21 ZA ZA9701514A patent/ZA971514B/xx unknown
- 1997-02-21 BR BR9701046A patent/BR9701046A/pt not_active Application Discontinuation
- 1997-02-21 JP JP03724197A patent/JP3974677B2/ja not_active Expired - Fee Related
- 1997-02-21 NO NO970798A patent/NO307046B1/no unknown
- 1997-02-21 HR HR19606509.7 patent/HRP970101B1/xx not_active IP Right Cessation
- 1997-02-21 RU RU97102581/04A patent/RU2218329C2/ru not_active IP Right Cessation
- 1997-02-21 KR KR1019970005214A patent/KR100476796B1/ko not_active Expired - Fee Related
- 1997-02-21 CA CA002198176A patent/CA2198176A1/en not_active Abandoned
- 1997-02-21 HU HU9700502A patent/HUP9700502A3/hu unknown
- 1997-02-21 US US08/804,023 patent/US5856574A/en not_active Expired - Lifetime
- 1997-02-24 ID IDP970554A patent/ID16042A/id unknown
-
1999
- 1999-12-30 GR GR990403381T patent/GR3032293T3/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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