ES2144846T3 - Metodos y composiciones para determinar la secuencia de moleculas de acidos nucleicos. - Google Patents

Metodos y composiciones para determinar la secuencia de moleculas de acidos nucleicos.

Info

Publication number
ES2144846T3
ES2144846T3 ES97905634T ES97905634T ES2144846T3 ES 2144846 T3 ES2144846 T3 ES 2144846T3 ES 97905634 T ES97905634 T ES 97905634T ES 97905634 T ES97905634 T ES 97905634T ES 2144846 T3 ES2144846 T3 ES 2144846T3
Authority
ES
Spain
Prior art keywords
nucleic acid
methods
sequence
labels
acid molecules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97905634T
Other languages
English (en)
Other versions
ES2144846T5 (es
Inventor
Ness Jeffrey Van
John C Tabone
J Jeffry Howbert
John T Mulligan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Qiagen Genomics Inc
Original Assignee
Qiagen Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26681206&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2144846(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Qiagen Genomics Inc filed Critical Qiagen Genomics Inc
Application granted granted Critical
Publication of ES2144846T3 publication Critical patent/ES2144846T3/es
Publication of ES2144846T5 publication Critical patent/ES2144846T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6872—Methods for sequencing involving mass spectrometry
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/11—Compounds covalently bound to a solid support
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Saccharide Compounds (AREA)

Abstract

SE PROPORCIONAN METODOS Y COMPUESTOS, INCLUYENDO COMPOSICIONES CONTENIENDO LOS MISMOS, PARA DETERMINAR LA SECUENCIA DE MOLECULAS DE ACIDOS NUCLEICOS. LOS METODOS PERMITEN LA DETERMINACION DE MULTIPLES SECUENCIAS DE ACIDOS NUCLEICOS SIMULTANEAMENTE. LOS COMPUESTOS SE UTILIZAN COMO ETIQUETAS PARA GENERAR FRAGMENTOS DE ACIDOS NUCLEICOS ETIQUETADOS QUE SON COMPLEMENTARIOS A UNA MOLECULA SE ACIDO NUCLEICO SELECCIONADA. CADA ETIQUETA ES CORRELATIVA CON UN DETERMINADO NUCLEOTIDO Y, EN UNA REALIZACION PREFERIDA, PUEDE DETECTARSE POR ESPECTROMETRIA DE MASAS. DESPUES DE LA SEPARACION DE LOS FRAGMENTOS ETIQUETADOS POR SU LONGITUD SECUENCIAL, LAS ETIQUETAS SE ESCINDEN DE LOS FRAGMENTOS ETIQUETADOS. EN UNA REALIZACION PREFERIDA, LAS ETIQUETAS SE DETECTAN MEDIANTE ESPECTROMETRIA DE MASAS Y LA SECUENCIA DE LA MOLECULA DE ACIDO NUCLEICO SE DETERMINA A PARTIR DE ESTAS. LOS PASOS INDIVIDUALES DE LOS METODOS PUEDEN UTILIZARSE EN FORMA AUTOMATICA, P. EJ., MEDIANTE SU INCORPORACION EN SISTEMAS.
ES97905634T 1996-01-23 1997-01-23 Metodos y composiciones para determinar la secuencia de moleculas de acidos nucleicos. Expired - Lifetime ES2144846T5 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US58926096A 1996-01-23 1996-01-23
US1046296P 1996-01-23 1996-01-23
US10462P 1996-01-23
US589260 1996-01-23

Publications (2)

Publication Number Publication Date
ES2144846T3 true ES2144846T3 (es) 2000-06-16
ES2144846T5 ES2144846T5 (es) 2006-07-16

Family

ID=26681206

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97905634T Expired - Lifetime ES2144846T5 (es) 1996-01-23 1997-01-23 Metodos y composiciones para determinar la secuencia de moleculas de acidos nucleicos.

Country Status (17)

Country Link
EP (1) EP0868535B9 (es)
JP (2) JP2001501449A (es)
KR (1) KR100482917B1 (es)
CN (1) CN1163619C (es)
AT (2) ATE425175T1 (es)
AU (1) AU717435B2 (es)
BR (1) BR9707056B1 (es)
CA (1) CA2243560A1 (es)
CZ (1) CZ218498A3 (es)
DE (2) DE69739304D1 (es)
ES (1) ES2144846T5 (es)
GR (1) GR3033733T3 (es)
HU (1) HUP9901321A3 (es)
NZ (1) NZ331044A (es)
PL (1) PL328271A1 (es)
PT (1) PT868535E (es)
WO (1) WO1997027331A2 (es)

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Also Published As

Publication number Publication date
CZ218498A3 (cs) 1998-12-16
DE69739304D1 (de) 2009-04-23
DE69701671D1 (de) 2000-05-18
HUP9901321A2 (hu) 1999-07-28
JP2008183012A (ja) 2008-08-14
ATE191750T1 (de) 2000-04-15
JP2001501449A (ja) 2001-02-06
BR9707056B1 (pt) 2009-05-05
CN1163619C (zh) 2004-08-25
GR3033733T3 (en) 2000-10-31
WO1997027331A2 (en) 1997-07-31
EP0868535B1 (en) 2000-04-12
DE69701671T2 (de) 2000-08-10
HUP9901321A3 (en) 2001-10-29
KR100482917B1 (ko) 2005-11-11
KR19990081925A (ko) 1999-11-15
ES2144846T5 (es) 2006-07-16
AU717435B2 (en) 2000-03-23
DE69701671T3 (de) 2006-08-17
WO1997027331A3 (en) 1998-04-02
AU2247397A (en) 1997-08-20
EP0868535A2 (en) 1998-10-07
BR9707056A (pt) 1999-12-28
CA2243560A1 (en) 1997-07-31
CN1212021A (zh) 1999-03-24
NZ331044A (en) 1999-02-25
EP0868535B2 (en) 2006-01-04
ATE425175T1 (de) 2009-03-15
PL328271A1 (en) 1999-01-18
PT868535E (pt) 2000-12-29
EP0868535B9 (en) 2007-05-09

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