ES2146581T3 - 2,4- y 2,5-bis-tetrazolilpiridinas, procedimiento para su preparacion, asi como su empleo como medicamentos. - Google Patents

2,4- y 2,5-bis-tetrazolilpiridinas, procedimiento para su preparacion, asi como su empleo como medicamentos.

Info

Publication number
ES2146581T3
ES2146581T3 ES92101709T ES92101709T ES2146581T3 ES 2146581 T3 ES2146581 T3 ES 2146581T3 ES 92101709 T ES92101709 T ES 92101709T ES 92101709 T ES92101709 T ES 92101709T ES 2146581 T3 ES2146581 T3 ES 2146581T3
Authority
ES
Spain
Prior art keywords
tetrazolilpiridinas
medicines
bis
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92101709T
Other languages
English (en)
Inventor
Gerrit Schubert
Ekkehard Baader
Martin Bickel
Volkmar Gunzler-Pukall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2146581T3 publication Critical patent/ES2146581T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

LA INVENCION SE REFIERE A PIRIDINAS 2,4OLIL. LOS COMPUESTOS CONOCIDOS INHIBEN LAS ENZIMAS PROLIN ISIN-HIDROXILASA Y EFECTUAN UNA INHIBICION SELECTIVA DE LA BIOSINTESIS DE COLAGENO. PUEDEN SER UTILIZADOS COMO FIBROSUPRESIVOS E INMUNOSUPRESIVOS.
ES92101709T 1991-02-05 1992-02-03 2,4- y 2,5-bis-tetrazolilpiridinas, procedimiento para su preparacion, asi como su empleo como medicamentos. Expired - Lifetime ES2146581T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4103372 1991-02-05

Publications (1)

Publication Number Publication Date
ES2146581T3 true ES2146581T3 (es) 2000-08-16

Family

ID=6424383

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92101709T Expired - Lifetime ES2146581T3 (es) 1991-02-05 1992-02-03 2,4- y 2,5-bis-tetrazolilpiridinas, procedimiento para su preparacion, asi como su empleo como medicamentos.

Country Status (23)

Country Link
US (2) US5482953A (es)
EP (1) EP0498334B1 (es)
JP (1) JPH0559041A (es)
KR (1) KR100214797B1 (es)
AT (1) ATE193288T1 (es)
AU (1) AU650511B2 (es)
CA (1) CA2060622A1 (es)
CZ (1) CZ283006B6 (es)
DE (1) DE59209838D1 (es)
DK (1) DK0498334T3 (es)
ES (1) ES2146581T3 (es)
FI (1) FI103117B1 (es)
GR (1) GR3033536T3 (es)
HR (1) HRP940840B1 (es)
HU (1) HUT61295A (es)
IE (1) IE920368A1 (es)
IL (1) IL100860A (es)
MX (1) MX9200492A (es)
NO (1) NO180446C (es)
NZ (1) NZ241505A (es)
PT (1) PT498334E (es)
YU (1) YU9492A (es)
ZA (1) ZA92788B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ305460B6 (cs) * 2013-05-06 2015-10-07 Contipro Biotech S.R.O. Způsob přípravy esteru 2-oxoglutarátu, přípravek obsahující ester 2-oxoglutarát a jeho použití

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3432094A1 (de) * 1984-08-31 1986-03-06 Hoechst Ag, 6230 Frankfurt Ester der pyridin-2,4- und -2,5- dicarbonsaeure als arzneimittel zur inhibierung der prolin- und lysinhydroxylase
DE3703963A1 (de) * 1987-02-10 1988-08-18 Hoechst Ag Pyridin-2,4- und 2,,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben, sowie arzneimittel auf basis dieser verbindungen
US5238948A (en) * 1987-02-10 1993-08-24 Hoechst Aktiengesellschaft Pyridine-2,4- and -2,5-dicarboxylic acid derivatives and medicaments based on these compounds
DE3703962A1 (de) * 1987-02-10 1988-08-18 Hoechst Ag Pyridin-2,4- und 2,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
DE3703959A1 (de) * 1987-02-10 1988-08-18 Hoechst Ag Pyridin-2,4- und 2,5-dicarbonsaeureamide, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
DE58908519D1 (de) * 1988-08-04 1994-11-24 Hoechst Ag Verbessertes Verfahren zur Herstellung von N,N-Bis(alkoxyalkyl)-pyridin -2,4-dicarbonsäurediamiden.
JPH02178263A (ja) * 1988-12-27 1990-07-11 Kaken Pharmaceut Co Ltd アザアズレン誘導体、その製造法およびそれを有効成分とする抗アレルギー剤および抗炎症剤
DE3924093A1 (de) * 1989-07-20 1991-02-07 Hoechst Ag N,n'-bis(alkoxy-alkyl)-pyridin-2,4-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung
FR2655801B1 (fr) * 1989-12-08 1992-03-13 Charbonnages De France Procede et dispositif de transmission de signaux video en milieu confine.
ZA91291B (en) * 1990-01-16 1991-09-25 Hoechst Ag Di(nitroxyalkyl)amides of pyridine-2,4-and-2,5-dicarboxylic acids,a process for the preparation thereof,and the use thereof
DE4020570A1 (de) * 1990-06-28 1992-01-02 Hoechst Ag 2,4- und 2,5-substituierte pyridin-n-oxide, verfahren zu deren herstellung sowie deren verwendung

Also Published As

Publication number Publication date
DK0498334T3 (da) 2000-09-18
JPH0559041A (ja) 1993-03-09
US5614537A (en) 1997-03-25
HRP940840A2 (en) 1997-06-30
KR100214797B1 (ko) 1999-08-02
IL100860A0 (en) 1992-11-15
FI920460A0 (fi) 1992-02-03
ATE193288T1 (de) 2000-06-15
GR3033536T3 (en) 2000-09-29
HU9200336D0 (en) 1992-04-28
IE920368A1 (en) 1992-08-12
US5482953A (en) 1996-01-09
NO180446C (no) 1997-04-23
KR920016443A (ko) 1992-09-24
EP0498334B1 (de) 2000-05-24
NO920462L (no) 1992-08-06
MX9200492A (es) 1992-08-01
FI103117B (fi) 1999-04-30
AU1072492A (en) 1992-08-13
IL100860A (en) 1995-11-27
DE59209838D1 (de) 2000-06-29
AU650511B2 (en) 1994-06-23
FI920460L (fi) 1992-08-06
NO920462D0 (no) 1992-02-04
FI103117B1 (fi) 1999-04-30
YU9492A (sh) 1995-03-27
CZ283006B6 (cs) 1997-12-17
PT498334E (pt) 2000-09-29
NO180446B (no) 1997-01-13
HUT61295A (en) 1992-12-28
CA2060622A1 (en) 1992-08-06
EP0498334A1 (de) 1992-08-12
NZ241505A (en) 1994-12-22
ZA92788B (en) 1992-10-28
CS30992A3 (en) 1992-11-18
HRP940840B1 (en) 2000-12-31

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