ES2147607T3 - Procedimiento y dispositivo para la deteccion de celulas diana especificas en poblaciones de celulas especializadas o mezcladas y en soluciones que contienen poblaciones de celulas mezcladas. - Google Patents

Procedimiento y dispositivo para la deteccion de celulas diana especificas en poblaciones de celulas especializadas o mezcladas y en soluciones que contienen poblaciones de celulas mezcladas.

Info

Publication number
ES2147607T3
ES2147607T3 ES95913431T ES95913431T ES2147607T3 ES 2147607 T3 ES2147607 T3 ES 2147607T3 ES 95913431 T ES95913431 T ES 95913431T ES 95913431 T ES95913431 T ES 95913431T ES 2147607 T3 ES2147607 T3 ES 2147607T3
Authority
ES
Spain
Prior art keywords
cell populations
mixed cell
enzymes
diana
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95913431T
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English (en)
Inventor
Oystein Fodstad
Hanne Kleppe Hoifodt
Philip D Rye
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Individual
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Individual
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=19896917&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2147607(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2147607T3 publication Critical patent/ES2147607T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57575—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving oncogenic proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/809—Multifield plates or multicontainer arrays

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

LA INVENCION SE REFIERE A UN METODO Y APARATO PARA DETECTAR CELULAS DIANA ESPECIFICAS EN MODO SIMPLE Y CON AHORRO DE TIEMPO, QUE UTILIZA PARTICULAS PARAMAGNETICAS, ANTICUERPOS QUE RECONOCEN LAS PARTES FC DE ANTICUERPOS ASOCIADOS A CELULAS DIANA Y ANTICUERPOS ASOCIADOS A CELULAS DIANA DIRIGIDOS A DETERMINANTES DE ANTIGENO ESPECIFICOS EN LAS MEMBRANAS DE CELULAS DIANA. LA INCUBACION DE LA SUSPENSION DE CELULA CON DETERGENTE Y/O SEGUNDOS ANTICUERPOS O FRAGMENTOS DE ANTICUERPOS, PREMARCADOS O NO CON AGENTES FLUORESCENTES, METACOLOIDES, RADIOISOTOPOS, COMPLEJOS DE BIOTINA O CIERTAS ENZIMAS QUE PERMITEN LA VISUALIZACION, AUMENTAN EN GRAN MEDIDA LA ESPECIFICIDAD DEL METODO. EL METODO Y APARATO DESCRITOS PROPORCIONAN UN SOPORTE SOLIDO Y REGISTRO PERMANENTE QUE ES VISUALIZADO FACILMENTE POR MICROSCOPIO, PERMITE LA VISUALIZACION Y LA CUANTIFICACION DE LA TOTALIDAD DEL ESPECIMEN MAS QUE DE PEQUEÑAS FRACCIONES DEL MISMO Y PERMITE LA UTILIZACION VOLUMENES DE ESPECIMENES GRANDES A SER ANALIZADOS, EL DISPOSITIVO PUEDE TAMBIEN SER EXPLORADO AUTOMATICAMENTE POR TECNOLOGIA DENSITOMETRICA CONVENCIONAL. EL METODO Y APARATO PUEDEN SER UTILIZADOS PARA AISLAMIENTO DE CELULAS DIANA POR LA APLICACION DE CAMPO MAGNETICO, Y SE DESCRIBE UN KIT Y APARATO PARA LLEVAR A CABO EL METODO DE ACUERDO A LA INVENCION.
ES95913431T 1994-03-10 1995-03-10 Procedimiento y dispositivo para la deteccion de celulas diana especificas en poblaciones de celulas especializadas o mezcladas y en soluciones que contienen poblaciones de celulas mezcladas. Expired - Lifetime ES2147607T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NO940866A NO180658C (no) 1994-03-10 1994-03-10 Fremgangsmåte og anordning for deteksjon av spesifikke målceller i spesialiserte eller blandede cellepopulasjoner og opplösninger som inneholder blandede cellepopulasjoner

Publications (1)

Publication Number Publication Date
ES2147607T3 true ES2147607T3 (es) 2000-09-16

Family

ID=19896917

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95913431T Expired - Lifetime ES2147607T3 (es) 1994-03-10 1995-03-10 Procedimiento y dispositivo para la deteccion de celulas diana especificas en poblaciones de celulas especializadas o mezcladas y en soluciones que contienen poblaciones de celulas mezcladas.

Country Status (18)

Country Link
US (1) US6265229B1 (es)
EP (1) EP0749580B2 (es)
JP (1) JP4071824B2 (es)
AT (1) ATE191973T1 (es)
AU (1) AU690244B2 (es)
CA (1) CA2185128C (es)
CZ (1) CZ265296A3 (es)
DE (1) DE69516401T3 (es)
DK (1) DK0749580T3 (es)
ES (1) ES2147607T3 (es)
FI (1) FI963533A7 (es)
GR (1) GR3033946T3 (es)
HU (1) HU221278B1 (es)
NO (1) NO180658C (es)
PL (1) PL177483B1 (es)
PT (1) PT749580E (es)
SK (1) SK115196A3 (es)
WO (1) WO1995024648A1 (es)

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NO940866L (no) 1995-09-11
SK115196A3 (en) 1997-06-04
PL177483B1 (pl) 1999-11-30
EP0749580B1 (en) 2000-04-19
CA2185128A1 (en) 1995-09-14
HU221278B1 (en) 2002-09-28
EP0749580A1 (en) 1996-12-27
PT749580E (pt) 2000-10-31
DE69516401T3 (de) 2006-06-01
JPH09510779A (ja) 1997-10-28
AU2086495A (en) 1995-09-25
NO940866D0 (no) 1994-03-10
US6265229B1 (en) 2001-07-24
HU9602432D0 (en) 1996-11-28
EP0749580B2 (en) 2005-07-27
DE69516401D1 (de) 2000-05-25
DE69516401T2 (de) 2001-01-04
FI963533A0 (fi) 1996-09-09
NO180658C (no) 1997-05-21
ATE191973T1 (de) 2000-05-15
AU690244B2 (en) 1998-04-23
FI963533A7 (fi) 1996-11-07
CA2185128C (en) 2009-01-13
DK0749580T3 (da) 2000-10-23
WO1995024648A1 (en) 1995-09-14
CZ265296A3 (en) 1997-10-15
GR3033946T3 (en) 2000-11-30
PL316209A1 (en) 1996-12-23
JP4071824B2 (ja) 2008-04-02
HUT75370A (en) 1997-05-28
NO180658B (no) 1997-02-10

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