ES2149174T3 - Un sistema de vacunacion de una sola dosis. - Google Patents
Un sistema de vacunacion de una sola dosis.Info
- Publication number
- ES2149174T3 ES2149174T3 ES92907229T ES92907229T ES2149174T3 ES 2149174 T3 ES2149174 T3 ES 2149174T3 ES 92907229 T ES92907229 T ES 92907229T ES 92907229 T ES92907229 T ES 92907229T ES 2149174 T3 ES2149174 T3 ES 2149174T3
- Authority
- ES
- Spain
- Prior art keywords
- water
- biologically active
- active material
- insoluble
- single dose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000002255 vaccination Methods 0.000 title 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 4
- 239000011149 active material Substances 0.000 abstract 3
- 239000000463 material Substances 0.000 abstract 3
- 239000007943 implant Substances 0.000 abstract 2
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 2
- -1 ANTIBODIES Substances 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 239000007888 film coating Substances 0.000 abstract 1
- 238000009501 film coating Methods 0.000 abstract 1
- 239000007952 growth promoter Substances 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 238000002513 implantation Methods 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 235000015097 nutrients Nutrition 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 235000013343 vitamin Nutrition 0.000 abstract 1
- 239000011782 vitamin Substances 0.000 abstract 1
- 229940088594 vitamin Drugs 0.000 abstract 1
- 229930003231 vitamin Natural products 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
LA INVENCION PRESENTA UN IMPLANTE FARMACEUTICO O VETERINARIO, QUE CUANDO SE ADMINISTRA PARENTERALMENTE LIBERA UN IMPULSO DE AL MENOS UN MATERIAL BIOLOGICAMENTE ACTIVO EN UN INTERVALO DE TIEMPO CONTROLABLE TRAS LA IMPLANTACION. EL IMPLANTE CONTIENE EL MATERIAL BIOLOGICAMENTE ACTIVO; UN EXCIPIENTE QUE CONTIENE AL MENOS UN MATERIAL SOLUBLE EN AGUA Y AL MENOS UN MATERIAL INSOLUBLE EN AGUA; UN REVESTIMIENTO DE PELICULA POLIMERICA ADAPTADO PARA ROMPERSE EN UN PERIODO DE TIEMPO PREDETERMINADO DESPUES DE LA IMPLANTACION Y EN DONDE LOS EXCIPIENTES Y LOS POLIMEROS SON BIOCOMPATIBLES. EL MATERIAL BIOLOGICAMENTE ACTIVO SE SELECCIONA DEL GRUPO QUE CONSISTE EN ANTIGENOS, ANTICUERPOS, HORMONAS, PROMOTORES DEL CRECIMIENTO, ANTIBIOTICOS, NUTRIENTES, MINERALES Y VITAMINAS. PREFERENTEMENTE, EL EXCIPIENTE CONTIENE UNA COMBINACION DE DOS O MAS MATERIALES SOLUBLES EN AGUA E INSOLUBLES EN AGUA.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPK526891 | 1991-03-26 | ||
| PCT/AU1992/000124 WO1992017165A1 (en) | 1991-03-26 | 1992-03-25 | A single dose vaccination system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2149174T3 true ES2149174T3 (es) | 2000-11-01 |
Family
ID=3775296
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES92907229T Expired - Lifetime ES2149174T3 (es) | 1991-03-26 | 1992-03-25 | Un sistema de vacunacion de una sola dosis. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5593697A (es) |
| EP (1) | EP0576522B1 (es) |
| AT (1) | ATE194910T1 (es) |
| CA (1) | CA2106952C (es) |
| DE (1) | DE69231291T2 (es) |
| ES (1) | ES2149174T3 (es) |
| NZ (2) | NZ242065A (es) |
| WO (1) | WO1992017165A1 (es) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5358502A (en) * | 1993-02-25 | 1994-10-25 | Pfizer Inc | PH-triggered osmotic bursting delivery devices |
| WO1994022476A1 (en) * | 1993-03-29 | 1994-10-13 | Pfizer Inc. | Multicomponent clostridial vaccines using saponin adjuvants |
| CA2183684C (en) * | 1994-02-18 | 2008-07-15 | Richard D. Hansen | Inoculation of animals with dried, pelleted biological materials |
| US5980508A (en) * | 1994-06-22 | 1999-11-09 | Controlled Release Technologies Pty Ltd | Controlled release device and method |
| FR2723536A1 (fr) * | 1994-08-11 | 1996-02-16 | Seth Pawan | Composition permettant une liberation selective d'un principe actif |
| AUPM897594A0 (en) * | 1994-10-25 | 1994-11-17 | Daratech Pty Ltd | Controlled release container |
| US5840332A (en) * | 1996-01-18 | 1998-11-24 | Perio Products Ltd. | Gastrointestinal drug delivery system |
| US6143037A (en) * | 1996-06-12 | 2000-11-07 | The Regents Of The University Of Michigan | Compositions and methods for coating medical devices |
| US6140475A (en) * | 1997-04-11 | 2000-10-31 | Altus Biologics Inc. | Controlled dissolution crosslinked protein crystals |
| ES2320603T3 (es) | 1997-07-30 | 2009-05-25 | Emory University | Sistemas de expresion, vectores, adn, proteinas de mineralizacion osea novedosos. |
| JP2001519379A (ja) * | 1997-10-09 | 2001-10-23 | ペリオ、プロダクツ、リミテッド | 遅延性総放出胃腸薬物送達システム |
| US6541606B2 (en) | 1997-12-31 | 2003-04-01 | Altus Biologics Inc. | Stabilized protein crystals formulations containing them and methods of making them |
| TR200003225T2 (tr) * | 1998-03-02 | 2001-02-21 | Applied Vaccine Technologies Copr. | Bağışıklık tepkisini modüle etmek için yöntemler ve araçlar |
| US6531152B1 (en) | 1998-09-30 | 2003-03-11 | Dexcel Pharma Technologies Ltd. | Immediate release gastrointestinal drug delivery system |
| ATE269114T1 (de) | 1998-11-20 | 2004-07-15 | Univ Connecticut | Verfahren und vorrichtung zur steuerung der gewebeimplantat-interaktionen |
| US20030099682A1 (en) * | 1998-11-20 | 2003-05-29 | Francis Moussy | Apparatus and method for control of tissue/implant interactions |
| US6217895B1 (en) | 1999-03-22 | 2001-04-17 | Control Delivery Systems | Method for treating and/or preventing retinal diseases with sustained release corticosteroids |
| US20040121014A1 (en) * | 1999-03-22 | 2004-06-24 | Control Delivery Systems, Inc. | Method for treating and/or preventing retinal diseases with sustained release corticosteroids |
| US6632451B2 (en) | 1999-06-04 | 2003-10-14 | Dexcel Pharma Technologies Ltd. | Delayed total release two pulse gastrointestinal drug delivery system |
| US6245913B1 (en) | 1999-06-30 | 2001-06-12 | Wockhardt Europe Limited | Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole |
| US7030097B1 (en) | 1999-07-14 | 2006-04-18 | Cornell Research Foundation, Inc. | Controlled nucleic acid delivery systems |
| US6592869B2 (en) * | 1999-08-24 | 2003-07-15 | Teva Pharmaceutical Industries, Ltd. | Vaccine composition and method of using the same |
| IL148247A0 (en) | 1999-08-24 | 2002-09-12 | Teva Pharma | A vaccine composition and method of using the same |
| US6375972B1 (en) | 2000-04-26 | 2002-04-23 | Control Delivery Systems, Inc. | Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof |
| DE10035156A1 (de) * | 2000-07-19 | 2002-02-07 | Biotecon Ges Fuer Biotechnologische Entwicklung & Consulting Mbh | Proteinkomplex als Vehikel für oral verfügbare Protein-Arzneimittel |
| US7575780B2 (en) * | 2000-08-07 | 2009-08-18 | Orthogen Llc | Method for manufacturing particles for use in forming a resorbable implant for stimulating bone growth |
| GB0025208D0 (en) | 2000-10-13 | 2000-11-29 | Euro Celtique Sa | Delayed release pharmaceutical formulations |
| US20070281003A1 (en) | 2001-10-12 | 2007-12-06 | Fuisz Richard C | Polymer-Based Films and Drug Delivery Systems Made Therefrom |
| US20110033542A1 (en) | 2009-08-07 | 2011-02-10 | Monosol Rx, Llc | Sublingual and buccal film compositions |
| US20190328679A1 (en) | 2001-10-12 | 2019-10-31 | Aquestive Therapeutics, Inc. | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
| US7357891B2 (en) | 2001-10-12 | 2008-04-15 | Monosol Rx, Llc | Process for making an ingestible film |
| US11207805B2 (en) | 2001-10-12 | 2021-12-28 | Aquestive Therapeutics, Inc. | Process for manufacturing a resulting pharmaceutical film |
| US8603514B2 (en) | 2002-04-11 | 2013-12-10 | Monosol Rx, Llc | Uniform films for rapid dissolve dosage form incorporating taste-masking compositions |
| US8900497B2 (en) | 2001-10-12 | 2014-12-02 | Monosol Rx, Llc | Process for making a film having a substantially uniform distribution of components |
| US8765167B2 (en) | 2001-10-12 | 2014-07-01 | Monosol Rx, Llc | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
| US8900498B2 (en) | 2001-10-12 | 2014-12-02 | Monosol Rx, Llc | Process for manufacturing a resulting multi-layer pharmaceutical film |
| US10285910B2 (en) | 2001-10-12 | 2019-05-14 | Aquestive Therapeutics, Inc. | Sublingual and buccal film compositions |
| DE60323482D1 (de) | 2002-05-06 | 2008-10-23 | Massachusetts Inst Technology | Diffusionskontrollierte arzneiform sowie herstellungsmethode mittels dreidimensionalem drucken |
| US8871241B2 (en) * | 2002-05-07 | 2014-10-28 | Psivida Us, Inc. | Injectable sustained release delivery devices |
| US20050152939A1 (en) * | 2002-05-22 | 2005-07-14 | Bunt Craig R. | Delivery technology |
| US20030224020A1 (en) * | 2002-05-31 | 2003-12-04 | Zabudkin Alexander F. | Pharmaceutical preparation of botulinum neurotoxin, methods of synthesis and methods of clinical use |
| KR100628263B1 (ko) * | 2002-08-21 | 2006-09-27 | 엘지.필립스 엘시디 주식회사 | 액정표시소자 |
| US7452350B2 (en) * | 2003-07-09 | 2008-11-18 | Yeakley Rourke M | Pre-dosed oral liquid medication dispensing system |
| EP2384753B1 (en) * | 2003-08-29 | 2016-01-06 | The Brigham and Women's Hospital, Inc. | Hydantoin derivatives as inhibitors of cellular necrosis |
| US20060280795A1 (en) * | 2005-06-08 | 2006-12-14 | Dexcel Pharma Technologies, Ltd. | Specific time-delayed burst profile delivery system |
| US8486070B2 (en) | 2005-08-23 | 2013-07-16 | Smith & Nephew, Inc. | Telemetric orthopaedic implant |
| EP1986601A2 (en) * | 2006-01-20 | 2008-11-05 | MonoSol Rx LLC | Film lined pouch and method of manufacturing this pouch |
| WO2007103276A2 (en) * | 2006-03-03 | 2007-09-13 | Smith & Nephew, Inc. | Systems and methods for delivering a medicament |
| EP2077824A4 (en) * | 2006-09-29 | 2012-07-18 | Monosol Rx Llc | CONDITIONING IN WHICH A FILM IS INCORPORATED AND METHOD FOR MANUFACTURING THE SAME |
| JP2012513481A (ja) | 2008-12-23 | 2012-06-14 | プレジデント アンド フェロウズ オブ ハーバード カレッジ | ネクロトーシスの小分子阻害剤 |
| WO2011079232A1 (en) * | 2009-12-23 | 2011-06-30 | Psivida Us, Inc. | Sustained release delivery devices |
| US8109917B2 (en) * | 2010-01-18 | 2012-02-07 | Rourke M. Yeakley | Twistable medication dispensing system |
| US8206368B2 (en) * | 2010-01-18 | 2012-06-26 | Rourke M. Yeakley | Multi-chamber mixture dispensing system |
| US9149959B2 (en) | 2010-10-22 | 2015-10-06 | Monosol Rx, Llc | Manufacturing of small film strips |
| US20140377320A1 (en) | 2011-12-22 | 2014-12-25 | Chuv, Centre Hospitalier Universitaire Vaudois | Selective Plasma Activation for Medical Implants and Wound Healing Devices |
| MX355912B (es) | 2012-02-22 | 2018-05-04 | Duchesnay Inc | Formulación de doxilamina y piridoxina y/o sus metabolitos o sales. |
| US9717583B2 (en) | 2014-03-13 | 2017-08-01 | Cell and Molecular Tissue Engineering, LLC | Sensors, cannulas, collars and coated surgical mesh, and corresponding systems and methods |
| US20160024098A1 (en) | 2013-03-15 | 2016-01-28 | President And Fellows Of Harvard College | Hybrid necroptosis inhibitors |
| CA2906945A1 (en) * | 2013-03-15 | 2014-09-18 | Incube Labs, Llc | Multi-stage biodegradable drug delivery platform |
| SG11201600122RA (en) | 2013-07-22 | 2016-02-26 | Duchesnay Inc | Composition for the management of nausea and vomiting |
| SG11201704764PA (en) | 2014-12-11 | 2017-07-28 | Harvard College | Inhibitors of cellular necrosis and related methods |
| US12427121B2 (en) | 2016-05-05 | 2025-09-30 | Aquestive Therapeutics, Inc. | Enhanced delivery epinephrine compositions |
| US11273131B2 (en) | 2016-05-05 | 2022-03-15 | Aquestive Therapeutics, Inc. | Pharmaceutical compositions with enhanced permeation |
| WO2017192921A1 (en) | 2016-05-05 | 2017-11-09 | Monosol Rx, Llc | Enhanced delivery epinephrine compositions |
| US12433850B2 (en) | 2016-05-05 | 2025-10-07 | Aquestive Therapeutics, Inc. | Enhanced delivery epinephrine and prodrug compositions |
| US12465564B2 (en) | 2021-10-25 | 2025-11-11 | Aquestive Therapeutics, Inc. | Oral and nasal compositions and methods of treatment |
| CN120241585A (zh) * | 2025-05-07 | 2025-07-04 | 长江大学 | 一种疫苗缓释埋植体及其应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3247066A (en) * | 1962-09-12 | 1966-04-19 | Parke Davis & Co | Controlled release dosage form containing water-swellable beadlet |
| FR2454804B1 (fr) * | 1979-04-26 | 1986-11-21 | Sanofi Sa | Medicament a base de dihydroergotoxine et son procede de preparation |
| ZA86252B (en) * | 1985-01-30 | 1986-09-24 | Warner Lambert Co | Coated dosage forms |
| DE3678641D1 (de) * | 1985-08-16 | 1991-05-16 | Procter & Gamble | Partikel mit konstanter wirkstofffreisetzung. |
| US5011692A (en) * | 1985-12-28 | 1991-04-30 | Sumitomo Pharmaceuticals Company, Limited | Sustained pulsewise release pharmaceutical preparation |
| EP0270575A4 (en) * | 1986-05-16 | 1988-10-20 | Victoria State | BIO-COMPATIBLE IMPLANTS. |
| DK0463061T3 (da) * | 1989-03-17 | 1993-07-12 | Pitman Moore Inc | Controlled-release tilførselsindretning til afgivelse af makromolekylære proteiner |
| US5026559A (en) * | 1989-04-03 | 1991-06-25 | Kinaform Technology, Inc. | Sustained-release pharmaceutical preparation |
| EP0408496A3 (en) * | 1989-07-12 | 1992-07-01 | Ciba-Geigy Ag | Solid dosage form for pharmaceutical substances |
| JPH03197421A (ja) * | 1989-12-26 | 1991-08-28 | Takeda Chem Ind Ltd | 徐放性錠剤 |
| US5091185A (en) * | 1990-06-20 | 1992-02-25 | Monsanto Company | Coated veterinary implants |
-
1992
- 1992-03-19 NZ NZ242065A patent/NZ242065A/en unknown
- 1992-03-19 NZ NZ286242A patent/NZ286242A/en unknown
- 1992-03-25 WO PCT/AU1992/000124 patent/WO1992017165A1/en not_active Ceased
- 1992-03-25 US US08/119,174 patent/US5593697A/en not_active Expired - Fee Related
- 1992-03-25 EP EP92907229A patent/EP0576522B1/en not_active Expired - Lifetime
- 1992-03-25 AT AT92907229T patent/ATE194910T1/de not_active IP Right Cessation
- 1992-03-25 ES ES92907229T patent/ES2149174T3/es not_active Expired - Lifetime
- 1992-03-25 DE DE69231291T patent/DE69231291T2/de not_active Expired - Fee Related
- 1992-03-25 CA CA002106952A patent/CA2106952C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| NZ286242A (en) | 1997-11-24 |
| WO1992017165A1 (en) | 1992-10-15 |
| EP0576522B1 (en) | 2000-07-26 |
| DE69231291D1 (de) | 2000-08-31 |
| EP0576522A4 (en) | 1994-06-01 |
| DE69231291T2 (de) | 2001-01-18 |
| CA2106952A1 (en) | 1992-09-27 |
| CA2106952C (en) | 2003-01-21 |
| US5593697A (en) | 1997-01-14 |
| EP0576522A1 (en) | 1994-01-05 |
| ATE194910T1 (de) | 2000-08-15 |
| NZ242065A (en) | 1996-06-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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