ES2152304T3 - Procedimiento para el crecimiento del virus del sindrome reproductivo y respiratorio porcino y su uso en vacunas. - Google Patents

Procedimiento para el crecimiento del virus del sindrome reproductivo y respiratorio porcino y su uso en vacunas.

Info

Publication number
ES2152304T3
ES2152304T3 ES94907895T ES94907895T ES2152304T3 ES 2152304 T3 ES2152304 T3 ES 2152304T3 ES 94907895 T ES94907895 T ES 94907895T ES 94907895 T ES94907895 T ES 94907895T ES 2152304 T3 ES2152304 T3 ES 2152304T3
Authority
ES
Spain
Prior art keywords
virus
vaccines
growth
procedure
reproductive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94907895T
Other languages
English (en)
Inventor
Thomas Sanderson
Michael J Mcginley
Jeffrey J Zimmerman
Howard T Hill
Michael C Meetz
Eugene C Pirtle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Bayer Corp
Iowa State University Research Foundation Inc ISURF
Original Assignee
Bayer AG
Bayer Corp
Iowa State University Research Foundation Inc ISURF
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, Bayer Corp, Iowa State University Research Foundation Inc ISURF filed Critical Bayer AG
Application granted granted Critical
Publication of ES2152304T3 publication Critical patent/ES2152304T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/815Viral vaccine for porcine species, e.g. swine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

UN PROCESO PARA DESARROLLAR UN PRRSV EN UN CULTIVO DE TEJIDO QUE SEA SUSCEPTIBLE DE INFECCION PARA REPRODUCIR EXACTAMENTE EL VIRUS EN UNA CANTIDAD SUFICIENTE PARA PROTEGER LOS ANIMALES CONTRA PRRS O SER USADA PARA DIAGNOSTICAR PRRS O IDENTIFICAR LA ESTRUCTURA MOLECULAR DE PRRSV PARA DESARROLLAR PRODUCTOS RECOMBINANTES, QUE COMPRENDEN LA INOCULACION DEL VIRUS EN EL CULTIVO DE TEJIDO Y COSECHAR EL VIRUS REPRODUCIDO.
ES94907895T 1993-02-08 1994-01-26 Procedimiento para el crecimiento del virus del sindrome reproductivo y respiratorio porcino y su uso en vacunas. Expired - Lifetime ES2152304T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1491593A 1993-02-08 1993-02-08

Publications (1)

Publication Number Publication Date
ES2152304T3 true ES2152304T3 (es) 2001-02-01

Family

ID=21768529

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94907895T Expired - Lifetime ES2152304T3 (es) 1993-02-08 1994-01-26 Procedimiento para el crecimiento del virus del sindrome reproductivo y respiratorio porcino y su uso en vacunas.

Country Status (21)

Country Link
US (2) US5510258A (es)
EP (1) EP0683816B1 (es)
JP (1) JP3710095B2 (es)
KR (1) KR100374295B1 (es)
CN (1) CN1080300C (es)
AT (1) ATE197314T1 (es)
AU (1) AU681874B2 (es)
BG (1) BG63170B1 (es)
CZ (1) CZ289743B6 (es)
DE (1) DE69426228T2 (es)
DK (1) DK0683816T3 (es)
ES (1) ES2152304T3 (es)
FI (1) FI117513B (es)
GR (1) GR3035257T3 (es)
HU (1) HU218430B (es)
NO (1) NO317662B1 (es)
NZ (1) NZ261992A (es)
PL (1) PL178609B1 (es)
PT (1) PT683816E (es)
SK (1) SK98695A3 (es)
WO (1) WO1994018311A1 (es)

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US5846805A (en) 1991-08-26 1998-12-08 Boehringer Ingelheim Animal Health, Inc. Culture of swine infertility and respiratory syndrome virus in simian cells
US6042830A (en) * 1992-08-05 2000-03-28 Boehringer Ingelheim Vetmedica, Inc. Viral agent associated with mystery swine disease
US6080570A (en) * 1991-08-26 2000-06-27 Boehringer Ingelheim Vetmedica, Inc. Method of producing a vaccine for Swine Infertility and Respiratory Syndrome
US6982160B2 (en) * 1991-08-26 2006-01-03 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions that include SIRS virus
US6592873B1 (en) 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
US6380376B1 (en) 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US6773908B1 (en) 1992-10-30 2004-08-10 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
ES2074950B1 (es) * 1993-09-17 1996-03-16 Iberica Cyanamid Vacuna para la prevencion de la enfermedad reproductiva y respiratoria de la cerda.
US5690940A (en) * 1995-06-21 1997-11-25 Regents Of The University Of Minnesota Low pathogencity PRRS live virus vaccines and methods of preparation thereof
ES2102971B1 (es) 1996-01-25 1998-03-01 Hipra Lab Sa Nueva cepa atenuada del virus causante del sindrome respiratorio y reproductivo porcino (prrs), las vacunas y medios de diagnostico obtenibles con la misma y los procedimientos para su obtencion.
AU2277497A (en) * 1996-03-01 1997-09-16 Schering Corporation Porcine reproductive and respiratory syndrome vaccine
US5866401A (en) * 1996-03-01 1999-02-02 Schering Corporation Porcine reproductive and respiratory syndrome vaccine
US6015663A (en) * 1996-03-01 2000-01-18 The United States Of America As Represented By The Secretary Of Agriculture Restriction enzyme screen for differentiating porcine reproductive and respiratory syndrome virus strains
US5976537A (en) * 1996-07-02 1999-11-02 The United States Of America As Represented By The Secretary Of Agriculture Porcine reproductive and respiratory syndrome vaccine
FR2751224B1 (fr) * 1996-07-19 1998-11-20 Rhone Merieux Formule de vaccin polynucleotidique contre les pathologies respiratoires et de reproduction des porcs
DK0835930T3 (da) * 1996-10-09 2001-06-18 Akzo Nobel Nv Europæiske vaccinestammer af porcint reproduktions- og respirationssyndrom-virus. (PRRSV)
US20040224327A1 (en) * 1996-10-30 2004-11-11 Meulenberg Johanna Jacoba Maria Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
EP0839912A1 (en) * 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
WO1998035023A1 (en) * 1997-02-07 1998-08-13 Origen, Inc. Method for growing porcine reproductive and respiratory syndrome virus for use as vaccines and diagnostic assays
CZ297371B6 (cs) 1997-05-06 2006-11-15 Boehringer Ingelheim Vetmedica Gmbh Peptid mající 5 az 15 aminokyselinových zbytku vyvolávající tvorbu protilátek, protilátka reaktivnís tímto peptidem a diagnostická testovací souprava
AU8393398A (en) * 1997-07-10 1999-02-08 Regents Of The University Of Minnesota Causative agent of sow abortion and mortality syndrome (sams), vaccine compositions, antibodies and method
UA78180C2 (uk) 1997-10-03 2007-03-15 Меріаль Кільцевий вірус свині типу ii, вакцини та діагностичні реагенти
FR2772047B1 (fr) 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
NZ513289A (en) 1998-12-22 2003-04-29 Pfizer Prod Inc Infectious cDNA clone of north american procine reproductive and respiratory syndrome (PRRS) virus and uses thereof
EP1157121B1 (en) 1999-03-08 2013-04-24 Boehringer Ingelheim Vetmedica GmbH Prrsv replicon
ES2388909T3 (es) 1999-04-22 2012-10-19 The United States Of America, As Represented Bythe Secretary Of Agriculture Vacuna contra el virus del síndrome respiratorio y reproductivo porcino basada en aislado JA-142 aislada
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Also Published As

Publication number Publication date
SK98695A3 (en) 1996-11-06
DE69426228D1 (de) 2000-12-07
DK0683816T3 (da) 2001-01-08
HU9502330D0 (en) 1996-05-28
CZ203195A3 (en) 1995-12-13
US5510258A (en) 1996-04-23
KR100374295B1 (ko) 2003-12-24
ATE197314T1 (de) 2000-11-15
AU681874B2 (en) 1997-09-11
HU218430B (hu) 2000-08-28
FI117513B (fi) 2006-11-15
FI953731L (fi) 1995-08-04
NZ261992A (en) 1996-06-25
NO953091L (no) 1995-08-07
BG63170B1 (bg) 2001-05-31
GR3035257T3 (en) 2001-04-30
CZ289743B6 (cs) 2002-03-13
DE69426228T2 (de) 2001-03-01
US5587164A (en) 1996-12-24
PL310126A1 (en) 1995-11-27
JPH08506486A (ja) 1996-07-16
CN1117742A (zh) 1996-02-28
JP3710095B2 (ja) 2005-10-26
NO317662B1 (no) 2004-11-29
EP0683816B1 (en) 2000-11-02
BG99850A (bg) 1996-02-28
AU6128594A (en) 1994-08-29
FI953731A0 (fi) 1995-08-04
PL178609B1 (pl) 2000-05-31
CN1080300C (zh) 2002-03-06
EP0683816A1 (en) 1995-11-29
WO1994018311A1 (en) 1994-08-18
HUT72917A (en) 1996-06-28
PT683816E (pt) 2001-03-30
NO953091D0 (no) 1995-08-07

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