ES2152948T3 - Derivados de imidazol, triazol y tetrazol. - Google Patents

Derivados de imidazol, triazol y tetrazol.

Info

Publication number
ES2152948T3
ES2152948T3 ES93907945T ES93907945T ES2152948T3 ES 2152948 T3 ES2152948 T3 ES 2152948T3 ES 93907945 T ES93907945 T ES 93907945T ES 93907945 T ES93907945 T ES 93907945T ES 2152948 T3 ES2152948 T3 ES 2152948T3
Authority
ES
Spain
Prior art keywords
tetrazol
triazol
imidazol
derivatives
receptors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93907945T
Other languages
English (en)
Inventor
Pineiro Jose Luis Castro
Victor Giulio Matassa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon Pharma UK Ltd
Original Assignee
Merck Sharp and Dohme Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp and Dohme Ltd filed Critical Merck Sharp and Dohme Ltd
Application granted granted Critical
Publication of ES2152948T3 publication Critical patent/ES2152948T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Paints Or Removers (AREA)
  • Lubricants (AREA)
  • Epoxy Resins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)

Abstract

UNA CLASE DE DERIVADOS SUSTITUIDOS DEL IMIDAZOL, DEL TRIAZOL Y DEL TETRAZOL SON AGONISTAS SELECTIVOS DE RECEPTORES SIMILARES AL 5-HT1 Y DE ESTE MODO SON UTILES EN EL TRATAMIENTO DE ESTADOS CLINICOS, EN PARTICULAR MIGRAÑAS Y ENFERMEDADES ASOCIADAS, POR LO QUE SE INDICA UN GRUPO DE AGONISTAS SELECTIVOS DE ESTOS RECEPTORES.
ES93907945T 1992-04-03 1993-03-29 Derivados de imidazol, triazol y tetrazol. Expired - Lifetime ES2152948T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929207396A GB9207396D0 (en) 1992-04-03 1992-04-03 Therapeutic agents

Publications (1)

Publication Number Publication Date
ES2152948T3 true ES2152948T3 (es) 2001-02-16

Family

ID=10713456

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93907945T Expired - Lifetime ES2152948T3 (es) 1992-04-03 1993-03-29 Derivados de imidazol, triazol y tetrazol.

Country Status (10)

Country Link
US (1) US5607957A (es)
EP (1) EP0637307B1 (es)
JP (1) JP3285581B2 (es)
AT (1) ATE197453T1 (es)
AU (1) AU675641B2 (es)
CA (1) CA2133076A1 (es)
DE (1) DE69329645T2 (es)
ES (1) ES2152948T3 (es)
GB (1) GB9207396D0 (es)
WO (1) WO1993020066A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9420529D0 (en) 1994-10-12 1994-11-30 Pfizer Ltd Indoles
US5484763A (en) * 1995-02-10 1996-01-16 American Cyanamid Company Substituted benzisoxazole and benzisothiazole herbicidal agents
EP1223932A4 (en) 1999-10-01 2003-01-15 Smithkline Beecham Corp COMPOUNDS AND METHODS
US20030176454A1 (en) * 2000-05-15 2003-09-18 Akira Yamada N-coating heterocyclic compounds
US7645886B2 (en) 2002-12-20 2010-01-12 Ciba Specialty Corporation Synthesis of amines and intermediates for the synthesis thereof
KR20150087400A (ko) 2012-11-20 2015-07-29 버텍스 파마슈티칼스 인코포레이티드 인돌아민 2,3-디옥시게나제의 억제제로서 유용한 화합물
PL3634417T3 (pl) 2017-05-17 2023-09-25 Arcus Biosciences, Inc. Pochodne chinazolino-pirazolowe do leczenia chorób związanych z nowotworem
GB201801226D0 (en) 2018-01-25 2018-03-14 Redx Pharma Plc Modulators of Rho-associated protein kinase
US12378229B2 (en) 2021-02-02 2025-08-05 Liminal Biosciences Limited GPR84 antagonists and uses thereof
AU2022309017A1 (en) 2021-07-07 2024-01-25 Terran Biosciences Inc. N,n-dimethyltryptamine and related psychedlics and uses thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1181741B (it) * 1984-12-04 1987-09-30 Glaxo Group Ltd Derivati di indolo,procedimento per prepararli e composizioni farmaceutiche che li contengono
US4833153A (en) * 1985-11-08 1989-05-23 Glaxo Group Limited Indole derivatives
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
GB8724912D0 (en) * 1987-10-23 1987-11-25 Wellcome Found Indole derivatives
NZ227841A (en) * 1988-02-12 1991-08-27 Merck Sharp & Dohme Heterocyclic compounds with at least two non-condensed five membered rings and pharmaceutical compositions
IL96891A0 (en) * 1990-01-17 1992-03-29 Merck Sharp & Dohme Indole-substituted five-membered heteroaromatic compounds,their preparation and pharmaceutical compositions containing them
PT97888B (pt) * 1990-06-07 1998-12-31 Zeneca Ltd Processo para a preparacao de compostos heterociclicos derivados de indol e de composicoes farmaceuticas que os contem
EP0494774A1 (en) * 1991-01-11 1992-07-15 MERCK SHARP & DOHME LTD. Indazole-substituted fivemembered heteroaromatic compounds
CZ283018B6 (cs) * 1991-02-01 1997-12-17 Merck Sharp And Dohme Limited Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi
HUT69705A (en) * 1991-11-25 1995-09-28 Pfizer Indole derivatives

Also Published As

Publication number Publication date
DE69329645T2 (de) 2001-05-10
GB9207396D0 (en) 1992-05-13
AU3895693A (en) 1993-11-08
ATE197453T1 (de) 2000-11-11
US5607957A (en) 1997-03-04
CA2133076A1 (en) 1993-10-14
EP0637307A1 (en) 1995-02-08
JP3285581B2 (ja) 2002-05-27
WO1993020066A1 (en) 1993-10-14
AU675641B2 (en) 1997-02-13
JPH07505382A (ja) 1995-06-15
EP0637307B1 (en) 2000-11-08
DE69329645D1 (de) 2000-12-14

Similar Documents

Publication Publication Date Title
ES2084702T3 (es) Imidazoles sustituidos utiles como inhibidores de la angiotensina ii.
UY23835A1 (es) Procedimiento para la preparacion de compuesto de acilo
ES2141913T3 (es) Agonistas y antagonistas de los receptores de la adenosina a1.
DE69719816D1 (de) N6-heterocyclisch substituierte Adenosin-Derivate
ES2196063T3 (es) Utilizacion de agentes antagonistas competitivos de progesterona para la preparacion de medicamentos destinados al tratamiento de hemorragias uterinas disfuncionales.
ES2138977T3 (es) Agonistas muscarinicos.
CY1115759T1 (el) Αντιβιοτικες συνθεσεις για θεραπεια του οφθαλμου
ES2040838T3 (es) Compuestos piperazinil-heterociclicos.
ES2174465T3 (es) Compuestos triazol y su utilizacion como ligandos de dopamina-d.
ES2167377T3 (es) Derivados de piridina farmacologicamente activos y procedimientos para la preparacion de los mismos.
ES2170102T3 (es) Aminociclohexilesteres y utilizacion de los mismos.
ES2153118T3 (es) Analogos heterociclicos de 1,2,4-triazolo 1,5-c)pirimidina que tienen una actividad antagonista sobre los receptores de adenosina a 2a?.
MX9203444A (es) Medicamentos.
ES2152948T3 (es) Derivados de imidazol, triazol y tetrazol.
PT1019426E (pt) Agonistas e antagonistas do receptor de adenosina a1
ES2056180T3 (es) Nuevos derivados de 2'-halometiliden, 2'-eteniliden y 2'-etinil citidina.
MX9304595A (es) Derivados de 1,2,4-triazola substituidos en 4
EA200200742A1 (ru) 1,2-диарилбензимидазолы для лечения заболеваний, связанных с активацией микроглии
MX9700959A (es) Derivados de becimidazol que tienen actividad dopaminergica.
ES2100689T3 (es) Asociacion sinergizante que tiene un efecto antagonista de los receptores nk1 y nk2.
ATE390124T1 (de) Behandlung von mastitis mit einer kombination aus prednisolon und cephalosporin
ES2048793T3 (es) Antibioticos antifungicos.
GT200400241A (es) Prevencion y tratamiento de enfermedades cardiacas hipertensivas mediante el uso de los estrogenos selectivos8b-vinil-estra-1,3,5,(10)-trien-3,17b-diol y 17b-fluor-9a-vinil-estra-1,3,6,(10)-trien-3, 16a-diol
ES2195010T3 (es) Derivados de di-arilalquenilaminas.
ES2140672T3 (es) Compuestos biciclicos sustituidos, fusionados y puentes utilizados como agentes terapeuticos.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 637307

Country of ref document: ES