ES2153498T3 - Proceso para preparar formas de dosificacion farmaceutica solidas. - Google Patents
Proceso para preparar formas de dosificacion farmaceutica solidas.Info
- Publication number
- ES2153498T3 ES2153498T3 ES95934712T ES95934712T ES2153498T3 ES 2153498 T3 ES2153498 T3 ES 2153498T3 ES 95934712 T ES95934712 T ES 95934712T ES 95934712 T ES95934712 T ES 95934712T ES 2153498 T3 ES2153498 T3 ES 2153498T3
- Authority
- ES
- Spain
- Prior art keywords
- water
- active substance
- pharmaceutically active
- dosage forms
- pharmaceutical dosage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D25/00—Filters formed by clamping together several filtering elements or parts of such elements
- B01D25/12—Filter presses, i.e. of the plate or plate and frame type
- B01D25/176—Filter presses, i.e. of the plate or plate and frame type attaching the filter element to the filter press plates, e.g. around the central feed hole in the plates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE PRESENTA UN PROCESO PARA LA PREPARACION DE UNA FORMA DE DOSIFICACION ORAL, SOLIDA, RAPIDAMENTE DESINTEGRABLE DE UNA SUSTANCIAS FARMACOLOGICAMENTE ACTIVA QUE TENGA UN SABOR NO ACEPTABLE, EL PROCESO COMPRENDE LA FORMACION DE UNA SOLUCION O DE UNA SUSPENSION EN UN SOLVENTE DE UNA FORMA DE UNA SUSTANCIA FARMACOLOGICAMENTE ACTIVA QUE SEA MENOS SOLUBLE EN AGUA Y MAS AGRADABLE AL GUSTO QUE LA FORMA CON EL SABOR INACEPTABLE JUNTO CON UN MATERIAL PORTADORA SOLUBLE O DISPERSIBLE EN AGUA, FORMANDO UNIDADES DISCRETAS DE LA SUSPENSION O SOLUCION Y ELIMINANDO EL SOLVENTE DE LAS UNIDADES DISCRETAS BAJO CONDICIONES MEDIANTE LAS CUALES SE FORME UNA RED DEL MATERIAL PORTADOR QUE LLEVA UNA DOSIS DE LA FORMA MENOS SOLUBLE Y MAS AGRADABLE AL GUSTO DE LA SUBSTANCIA FARMACOLOGICAMENTE ACTIVA.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9421837A GB9421837D0 (en) | 1994-10-28 | 1994-10-28 | Process for preparing solid pharmaceutical dosage forms |
| CA002134611A CA2134611C (en) | 1994-10-28 | 1994-10-28 | Process for preparing solid pharmaceutical dosage forms |
| US08/330,936 US5738875A (en) | 1994-10-28 | 1994-10-28 | Process for preparing solid pharmaceutical dosage forms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2153498T3 true ES2153498T3 (es) | 2001-03-01 |
Family
ID=27169885
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES95934712T Expired - Lifetime ES2153498T3 (es) | 1994-10-28 | 1995-10-20 | Proceso para preparar formas de dosificacion farmaceutica solidas. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5738875A (es) |
| EP (1) | EP0737065B1 (es) |
| JP (2) | JP3839845B2 (es) |
| CN (1) | CN1204877C (es) |
| AT (1) | ATE198150T1 (es) |
| AU (1) | AU3702895A (es) |
| CA (1) | CA2134611C (es) |
| DE (1) | DE69519664T2 (es) |
| DK (1) | DK0737065T3 (es) |
| ES (1) | ES2153498T3 (es) |
| GB (1) | GB9421837D0 (es) |
| GR (1) | GR3035194T3 (es) |
| MX (1) | MX9602514A (es) |
| PT (1) | PT737065E (es) |
| WO (1) | WO1996013252A1 (es) |
| ZA (1) | ZA959073B (es) |
Families Citing this family (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5738875A (en) * | 1994-10-28 | 1998-04-14 | R.P. Scherer Corporation | Process for preparing solid pharmaceutical dosage forms |
| US8071128B2 (en) * | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
| GB9702799D0 (en) * | 1997-02-12 | 1997-04-02 | Scherer Corp R P | Process for preparing solid pharmaceutical dosage forms |
| US20040023948A1 (en) * | 1997-03-24 | 2004-02-05 | Green Richard David | Fast-dispersing dosage form containing 5-HT1 agonists |
| US5976577A (en) * | 1997-07-11 | 1999-11-02 | Rp Scherer Corporation | Process for preparing fast dispersing solid oral dosage form |
| DE19821625C1 (de) * | 1998-05-15 | 2000-01-05 | Merck Patent Gmbh | Pharmazeutische Zubereitung |
| BR0007360A (pt) * | 1999-12-23 | 2001-08-14 | Johnson & Johnson | Composição de liberação controlada |
| WO2001064202A2 (en) * | 2000-03-01 | 2001-09-07 | Euro-Celtique S.A. | Tramadol for the treatment of functional gastrointestinal disorders |
| US6814978B2 (en) | 2000-12-29 | 2004-11-09 | Mcneil-Ppc, Inc. | Process for preparing a soft tablet |
| WO2002100381A1 (en) * | 2001-06-07 | 2002-12-19 | Tanabe Seiyaku Co., Ltd. | Functional grain-containing preparations quickly disintegrated in the oral cavity |
| PL368612A1 (en) * | 2001-08-14 | 2005-04-04 | Biotie Therapies Corporation | Method of treating alcoholism or alcohol abuse |
| JP2005519865A (ja) * | 2001-09-25 | 2005-07-07 | ランバクシー ラボラトリーズ リミテッド | 急速溶解性投薬形態物の製造方法 |
| CA2447984A1 (en) * | 2001-09-28 | 2003-04-03 | Mcneil-Ppc, Inc. | Dosage forms having an inner core and outer shell with different shapes |
| US9358214B2 (en) | 2001-10-04 | 2016-06-07 | Adare Pharmaceuticals, Inc. | Timed, sustained release systems for propranolol |
| EP1485296B1 (en) * | 2002-02-13 | 2011-07-20 | Michael K. Weibel | Drug dose - form and method of manufacture |
| WO2003077842A2 (en) * | 2002-03-12 | 2003-09-25 | Bristol-Myers Squibb Company | Palatable oral suspension and method |
| US20040001885A1 (en) * | 2002-06-27 | 2004-01-01 | Unchalee Kositprapa | Rapidly disintegrating antihistamine formulation |
| US7985422B2 (en) * | 2002-08-05 | 2011-07-26 | Torrent Pharmaceuticals Limited | Dosage form |
| US8367111B2 (en) * | 2002-12-31 | 2013-02-05 | Aptalis Pharmatech, Inc. | Extended release dosage forms of propranolol hydrochloride |
| US20040234579A1 (en) * | 2003-05-22 | 2004-11-25 | Mark D. Finke, Inc. | Dietary supplements and methods of preparing and administering dietary supplements |
| US20050036977A1 (en) * | 2003-08-11 | 2005-02-17 | Dilip Gole | Taste-masked resinate and preparation thereof |
| EP1670441A4 (en) * | 2003-10-07 | 2012-05-02 | Andrx Pharmaceuticals Llc | FAST RESOLUTION FORMULATION |
| DE20321887U1 (de) | 2003-11-10 | 2012-01-20 | Allergan, Inc. | Arzneimittel umfassend niedrige Dosierungen von Desmopressin |
| CA2866501A1 (en) | 2003-11-10 | 2005-05-26 | Allergan, Inc. | Pharmaceutical compositions including low dosages of desmopressin |
| EP1582221A1 (en) | 2004-03-31 | 2005-10-05 | Chiesi S.A. | Pharmaceutical oral compositions with a taste masking effect |
| US8545881B2 (en) | 2004-04-19 | 2013-10-01 | Eurand Pharmaceuticals, Ltd. | Orally disintegrating tablets and methods of manufacture |
| US8747895B2 (en) * | 2004-09-13 | 2014-06-10 | Aptalis Pharmatech, Inc. | Orally disintegrating tablets of atomoxetine |
| US9884014B2 (en) * | 2004-10-12 | 2018-02-06 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions |
| AU2005299490C1 (en) | 2004-10-21 | 2012-01-19 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions with gastrosoluble pore-formers |
| US20060105038A1 (en) * | 2004-11-12 | 2006-05-18 | Eurand Pharmaceuticals Limited | Taste-masked pharmaceutical compositions prepared by coacervation |
| ITMI20042356A1 (it) * | 2004-12-10 | 2005-03-10 | Acraf | Composizione farmaceutica orodisperdibile e procedimento per prepararla |
| US8697674B2 (en) * | 2004-12-29 | 2014-04-15 | Naturon, Inc. | Xanthurenic acid derivative pharmaceutical compositions and methods related thereto |
| US9161918B2 (en) | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
| GB0516604D0 (en) * | 2005-08-12 | 2005-09-21 | Sandoz Ag | Rapidly dispersing/disintegrating compositions |
| US7811604B1 (en) | 2005-11-14 | 2010-10-12 | Barr Laboratories, Inc. | Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same |
| US20070293580A1 (en) * | 2006-06-05 | 2007-12-20 | Malcolm Hill | Methods for Buccal, Lingual or Sublingual Dosing Regimens of Epinephrine for the Treatment of Allergic Emergencies |
| TW200817049A (en) * | 2006-06-05 | 2008-04-16 | Verus Pharmaceuticals Inc | Epinephrine dosing regimens comprising buccal, lingual or sublingual and injectable dosage forms |
| US8545879B2 (en) | 2009-08-31 | 2013-10-01 | Wilmington Pharmaceuticals, Llc | Fast disintegrating compositions of meloxicam |
| KR101765357B1 (ko) | 2009-12-02 | 2017-08-04 | 아데어 파마수티컬스 에스.알.엘. | 펙소페나딘 마이크로캡슐 및 그것을 함유하는 조성물 |
| AR079862A1 (es) * | 2010-01-08 | 2012-02-22 | Eurand Inc | Composicion de topiramato con sabor enmascarado, un comprimido desintegrable oralmente que comprende la misma y metodo de preparacion |
| US10548839B2 (en) * | 2010-03-16 | 2020-02-04 | Wei Tian | Process of manufacturing a lyophilized fast dissolving, multi-phasic dosage form |
| MX365568B (es) | 2010-12-02 | 2019-06-07 | Adare Pharmaceuticals Inc | Granulos de dispersion rapida, comprimidos de disolucion oral y metodos. |
| US9511028B2 (en) | 2012-05-01 | 2016-12-06 | Johnson & Johnson Consumer Inc. | Orally disintegrating tablet |
| CA2906107C (en) | 2013-03-15 | 2021-08-24 | Aprecia Pharmaceuticals Company | Rapidly dispersible dosage form of oxcarbazepine |
| AU2014228990B2 (en) | 2013-03-15 | 2017-02-02 | Aprecia Pharmaceuticals LLC | Rapid disperse dosage form containing levetiracetam |
| US9339489B2 (en) | 2013-03-15 | 2016-05-17 | Aprecia Pharmaceuticals Company | Rapid disperse dosage form containing levetiracetam |
| WO2014144661A1 (en) | 2013-03-15 | 2014-09-18 | Aprecia Pharmaceuticals Compny | Rapidly dispersible dosage form of topiramate |
| US9789066B2 (en) | 2014-01-10 | 2017-10-17 | Johnson & Johnson Consumer Inc. | Process for making tablet using radiofrequency and lossy coated particles |
| CA3018828C (en) | 2014-09-17 | 2021-05-11 | Steerlife India Private Limited | Effervescent composition and method of making it |
| WO2017098481A1 (en) | 2015-12-12 | 2017-06-15 | Steerlife India Private Limited | Effervescent compositions of metformin and processes for preparation thereof |
| WO2017168174A1 (en) | 2016-04-02 | 2017-10-05 | N4 Pharma Uk Limited | New pharmaceutical forms of sildenafil |
| WO2018002673A1 (en) | 2016-07-01 | 2018-01-04 | N4 Pharma Uk Limited | Novel formulations of angiotensin ii receptor antagonists |
| IT201600078683A1 (it) * | 2016-07-27 | 2018-01-27 | Mattia Saporiti | Matrice edibile per uso veterinario e zootecnico e relativo metodo di produzione |
| WO2018115888A1 (en) | 2016-12-21 | 2018-06-28 | N4 Pharma Uk Limited | Novel formulations of aprepitant |
| US10493026B2 (en) | 2017-03-20 | 2019-12-03 | Johnson & Johnson Consumer Inc. | Process for making tablet using radiofrequency and lossy coated particles |
| WO2020104837A1 (en) | 2018-11-21 | 2020-05-28 | Rosemont Pharmaceuticals Limited | Oral topiramate suspension formulations with extended shelf stability and enhanced bioavailability |
| GB2585413B (en) | 2019-02-22 | 2023-04-26 | Catalent Uk Swindon Zydis Ltd | Minimizing agglomeration of drug particle coating material during storage to stabilize disintegration times of pharmaceutical products |
| CN113507923B (zh) * | 2019-02-22 | 2024-03-26 | 康特伦英国斯温顿捷迪斯有限公司 | 在线混合期间混悬液的曝气最小化 |
| WO2020169989A1 (en) | 2019-02-22 | 2020-08-27 | Catalent U.K. Swindon Zydis Limited | Minimizing agglomeration, aeration, and preserving the coating of pharmaceutical compositions comprising ibuprofen |
| TWI849062B (zh) | 2019-02-22 | 2024-07-21 | 英商康泰倫特英國斯文敦載迪斯有限公司 | 保存水性懸浮液中以無溶劑混合方法製備的功能性塗覆之活性醫藥成份微粒 |
| AU2021296908A1 (en) | 2020-06-26 | 2023-02-16 | Aprecia Pharmaceuticals LLC | Rapidly-orodispersible tablets having an interior cavity |
| BR112023001716A2 (pt) | 2020-07-31 | 2023-04-04 | Catalent Uk Swindon Zydis Ltd | Composições farmacêuticas compreendendo api revestido |
| WO2022179634A1 (zh) * | 2021-02-27 | 2022-09-01 | 北京兴源联合医药科技有限公司 | 一种冻干口服制剂 |
| JP2024516827A (ja) | 2021-04-30 | 2024-04-17 | マインド メディシン, インコーポレイテッド | Lsd塩結晶形態 |
| AU2022331315B2 (en) | 2021-08-19 | 2025-10-16 | Definium Therapeutics US, Inc. | Lyophilized orally disintegrating tablet formulations of d-lysergic acid diethylamide for therapeutic applications |
| WO2025217640A1 (en) | 2024-04-12 | 2025-10-16 | Eli Lilly And Company | Compositions and methods for treating metabolic diseases |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE45770B1 (en) * | 1976-10-06 | 1982-11-17 | Wyeth John & Brother Ltd | Pharmaceutical dosage forms |
| GB1548022A (en) * | 1976-10-06 | 1979-07-04 | Wyeth John & Brother Ltd | Pharmaceutial dosage forms |
| CA1097233A (en) * | 1977-07-20 | 1981-03-10 | George K. E. Gregory | Packages |
| IE53696B1 (en) * | 1981-12-02 | 1989-01-18 | Wyeth John & Brother Ltd | Solid shaped articles |
| GB2111423B (en) * | 1981-12-02 | 1985-06-26 | Wyeth John & Brother Ltd | Making quick-dissolving pills |
| GB8528195D0 (en) * | 1985-11-15 | 1985-12-18 | Boots Co Plc | Therapeutic compositions |
| US5206025A (en) * | 1989-05-24 | 1993-04-27 | Rhone-Poulenc Sante | Porous pharmaceutical form and its preparation |
| US5079018A (en) * | 1989-08-14 | 1992-01-07 | Neophore Technologies, Inc. | Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs |
| US5039540A (en) * | 1989-08-14 | 1991-08-13 | Neophore Technologies, Inc. | Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs |
| US5215756A (en) * | 1989-12-22 | 1993-06-01 | Gole Dilip J | Preparation of pharmaceutical and other matrix systems by solid-state dissolution |
| US5188825A (en) * | 1989-12-28 | 1993-02-23 | Iles Martin C | Freeze-dried dosage forms and methods for preparing the same |
| EP0578823B1 (en) * | 1991-04-08 | 2002-01-23 | Sumitomo Pharmaceuticals Company, Limited | Porous solid preparation containing physiologically active protein substance |
| ATE172637T1 (de) * | 1991-12-24 | 1998-11-15 | Yamanouchi Pharma Co Ltd | Intrabukkal desintegrierende zubereitung und ihre herstellung |
| US5298261A (en) * | 1992-04-20 | 1994-03-29 | Oregon Freeze Dry, Inc. | Rapidly distintegrating tablet |
| JPH06298668A (ja) * | 1993-02-18 | 1994-10-25 | Takeda Chem Ind Ltd | 経口用医薬組成物 |
| US5382437A (en) * | 1993-10-25 | 1995-01-17 | Hunter Research Corporation | Frozen liquified gas composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs |
| US5738875A (en) * | 1994-10-28 | 1998-04-14 | R.P. Scherer Corporation | Process for preparing solid pharmaceutical dosage forms |
-
1994
- 1994-10-28 US US08/330,936 patent/US5738875A/en not_active Expired - Lifetime
- 1994-10-28 GB GB9421837A patent/GB9421837D0/en active Pending
- 1994-10-28 CA CA002134611A patent/CA2134611C/en not_active Expired - Lifetime
-
1995
- 1995-10-20 DK DK95934712T patent/DK0737065T3/da active
- 1995-10-20 MX MX9602514A patent/MX9602514A/es unknown
- 1995-10-20 EP EP95934712A patent/EP0737065B1/en not_active Expired - Lifetime
- 1995-10-20 CN CNB95191538XA patent/CN1204877C/zh not_active Expired - Lifetime
- 1995-10-20 ES ES95934712T patent/ES2153498T3/es not_active Expired - Lifetime
- 1995-10-20 JP JP51437996A patent/JP3839845B2/ja not_active Expired - Lifetime
- 1995-10-20 DE DE69519664T patent/DE69519664T2/de not_active Expired - Lifetime
- 1995-10-20 AU AU37028/95A patent/AU3702895A/en not_active Abandoned
- 1995-10-20 PT PT95934712T patent/PT737065E/pt unknown
- 1995-10-20 AT AT95934712T patent/ATE198150T1/de active
- 1995-10-20 WO PCT/GB1995/002486 patent/WO1996013252A1/en not_active Ceased
- 1995-10-26 ZA ZA959073A patent/ZA959073B/xx unknown
-
2001
- 2001-01-10 GR GR20010400012T patent/GR3035194T3/el unknown
-
2005
- 2005-12-22 JP JP2005370451A patent/JP2006111635A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006111635A (ja) | 2006-04-27 |
| ATE198150T1 (de) | 2001-01-15 |
| ZA959073B (en) | 1996-05-22 |
| DE69519664D1 (de) | 2001-01-25 |
| WO1996013252A1 (en) | 1996-05-09 |
| JP3839845B2 (ja) | 2006-11-01 |
| CA2134611C (en) | 2002-12-24 |
| CN1140407A (zh) | 1997-01-15 |
| CA2134611A1 (en) | 1996-04-29 |
| JPH09511256A (ja) | 1997-11-11 |
| US5738875A (en) | 1998-04-14 |
| CN1204877C (zh) | 2005-06-08 |
| AU3702895A (en) | 1996-05-23 |
| DE69519664T2 (de) | 2001-05-17 |
| GR3035194T3 (en) | 2001-04-30 |
| PT737065E (pt) | 2001-04-30 |
| MX9602514A (es) | 1997-05-31 |
| GB9421837D0 (en) | 1994-12-14 |
| EP0737065A1 (en) | 1996-10-16 |
| DK0737065T3 (da) | 2001-01-15 |
| EP0737065B1 (en) | 2000-12-20 |
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