ES2155802A1 - Procedimiento para reforzar y evaluar la eficacia de la actiovidad antitumoral de farmacos en bruto. - Google Patents

Procedimiento para reforzar y evaluar la eficacia de la actiovidad antitumoral de farmacos en bruto.

Info

Publication number
ES2155802A1
ES2155802A1 ES009902062A ES9902062A ES2155802A1 ES 2155802 A1 ES2155802 A1 ES 2155802A1 ES 009902062 A ES009902062 A ES 009902062A ES 9902062 A ES9902062 A ES 9902062A ES 2155802 A1 ES2155802 A1 ES 2155802A1
Authority
ES
Spain
Prior art keywords
antitumour
activating
polysaccharide
polysaccharide drugs
drugs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES009902062A
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English (en)
Other versions
ES2155802B1 (es
Inventor
Kozo Niwa
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Individual
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Individual
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Publication date
Application filed by Individual filed Critical Individual
Publication of ES2155802A1 publication Critical patent/ES2155802A1/es
Application granted granted Critical
Publication of ES2155802B1 publication Critical patent/ES2155802B1/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/071—Agaricus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0004—Homeopathy; Vitalisation; Resonance; Dynamisation, e.g. esoteric applications; Oxygenation of blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Endocrinology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Esta invención se refiere a un procedimiento para reforzar una actividad antitumoral mediante la tostadura de una seta que contiene {be}-glucano por rayos infrarrojos lejanos, después la fermentación mediante la adición de "koji", y además la obtención de un agente aceitoso, una composición que contiene un fármaco en bruto al que se aplica tal procedimiento, un procedimiento para evaluar y esperar que la actividad antitumoral en el momento de la administración interna sea mayor cuando aumenta la relación de la cantidad formada por peróxido de lípido, y un procedimiento para evaluar la eficacia antitumoral del tratamiento aplicado al fármaco en bruto mediante el uso de los procedimientos.
ES009902062A 1998-09-17 1999-09-16 Procedimiento para reforzar y evaluar la eficacia de la actiovidad antitumoral de farmacos en bruto. Expired - Lifetime ES2155802B1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP26375398 1998-09-17
JP10323374A JP2000159682A (ja) 1998-09-17 1998-11-13 生薬の抗腫瘍活性強化方法、抗腫瘍活性強化生薬含有組成物、生薬処理の抗腫瘍有効性評価方法、および生薬の抗腫瘍有効性評価方法

Publications (2)

Publication Number Publication Date
ES2155802A1 true ES2155802A1 (es) 2001-05-16
ES2155802B1 ES2155802B1 (es) 2001-12-01

Family

ID=26546176

Family Applications (1)

Application Number Title Priority Date Filing Date
ES009902062A Expired - Lifetime ES2155802B1 (es) 1998-09-17 1999-09-16 Procedimiento para reforzar y evaluar la eficacia de la actiovidad antitumoral de farmacos en bruto.

Country Status (19)

Country Link
JP (1) JP2000159682A (es)
KR (1) KR20000023206A (es)
CN (1) CN1255376A (es)
AU (1) AU4486299A (es)
BE (1) BE1012725A5 (es)
CA (1) CA2282234A1 (es)
DE (1) DE19944695A1 (es)
DK (1) DK199901235A (es)
ES (1) ES2155802B1 (es)
FR (2) FR2783426A1 (es)
GB (2) GB9920710D0 (es)
ID (1) ID23150A (es)
IL (1) IL131722A0 (es)
IS (1) IS5183A (es)
IT (1) IT1307267B1 (es)
NL (2) NL1013049C2 (es)
NO (1) NO994463L (es)
SE (2) SE9903307L (es)
SG (1) SG76631A1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100391439C (zh) * 2001-04-27 2008-06-04 味之素株式会社 免疫增强剂
CA2445713A1 (en) * 2001-05-07 2002-11-14 Gab-Gyun Shin A method for preparing lactic acid fermented solution of mushroom and lactic acid fermented solution of mushroom produced thereby
JP4499979B2 (ja) * 2001-05-21 2010-07-14 コンビ株式会社 病原菌感染抑制用組成物
JP4561098B2 (ja) * 2001-06-01 2010-10-13 味の素株式会社 糖尿病用薬剤
KR100971599B1 (ko) 2002-05-15 2010-07-20 비에이취엔 가부시끼가이샤 혈관 관련 질환의 예방 또는 치료를 위한 조성물
JP4681801B2 (ja) * 2002-05-15 2011-05-11 ビーエイチエヌ株式会社 血管新生阻害剤およびその製造方法
JP4826696B2 (ja) * 2003-04-07 2011-11-30 ビーエイチエヌ株式会社 血管新生阻害剤
JP2005089417A (ja) * 2003-09-19 2005-04-07 Noevir Co Ltd 糖尿病予防・治療用組成物
JP4587441B2 (ja) * 2004-02-12 2010-11-24 株式会社クレハ 新規な糖尿病治療剤および食品
KR20070041786A (ko) * 2004-09-17 2007-04-19 카부시키카이샤 에스·에스·아이 유방암을 억제하는 아가리쿠스 추출물
JP2006273835A (ja) * 2005-03-04 2006-10-12 Michishi Tani 悪性腫瘍治療剤及びそれを含む飲食品
US20120128856A1 (en) * 2009-07-31 2012-05-24 Ming East-West, Llc Maitake mushroom coffee
WO2011081024A1 (ja) * 2009-12-29 2011-07-07 株式会社富士見養蜂園 旨味食品及びその製造方法
CN106309511A (zh) * 2016-08-30 2017-01-11 青海民族大学 圆孢蘑菇抑制cdc25酶有效部位及制法和应用
CN106333969A (zh) * 2016-08-30 2017-01-18 青海民族大学 圆孢蘑菇抑制hdac1酶有效部位及制法和应用
WO2019104579A1 (en) * 2017-11-30 2019-06-06 SHIEH, Darbin Method for predicting and modulating susceptibility of cancer cell to programmed cell death
KR102602787B1 (ko) * 2020-12-16 2023-11-17 대한민국 꽃송이버섯 생리활성성분 및 영양성분의 함량을 증가시키는 방법
KR102646421B1 (ko) * 2020-12-16 2024-03-12 대한민국 잎새버섯 생리활성성분 및 영양성분의 함량을 증가시키는 방법
KR102584680B1 (ko) * 2020-12-17 2023-10-06 대한민국 생리활성 및 영양성분이 증가된 표고버섯차 제조방법

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4177108A (en) * 1977-03-02 1979-12-04 Tetsuro Ikekawa Process for producing emitanin
DE2842691A1 (de) * 1978-09-30 1980-04-10 Karl Dr Med Theurer Energetische anregung biologischer arzneimittel
ES2036496A1 (es) * 1991-08-14 1993-05-16 Kozo Niwa Composicion vegetal de bajo peso molecular compuesta por semilla de cardo mariano.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5276413A (en) * 1975-12-18 1977-06-27 Kureha Chem Ind Co Ltd Production of oncostatic substances
JPS57206618A (en) * 1981-06-12 1982-12-18 Noda Shiyokukin Kogyo Kk Preparation of antitumor substance
JPH02203765A (ja) * 1989-02-02 1990-08-13 Nippon Beet Sugar Mfg Co Ltd 抗腫瘍機能を有する食品及びその製造法
JP2955126B2 (ja) * 1992-06-22 1999-10-04 笑代 丹羽 医薬用油性製剤、食品用油性製剤およびそれらの製造方法
US6015913A (en) * 1996-09-06 2000-01-18 Mars, Incorporated Method for producing fat and/or solids from cocoa beans

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4177108A (en) * 1977-03-02 1979-12-04 Tetsuro Ikekawa Process for producing emitanin
DE2842691A1 (de) * 1978-09-30 1980-04-10 Karl Dr Med Theurer Energetische anregung biologischer arzneimittel
ES2036496A1 (es) * 1991-08-14 1993-05-16 Kozo Niwa Composicion vegetal de bajo peso molecular compuesta por semilla de cardo mariano.

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
KAWAZOE, T. et al.: "Efficient transformation of ergosterol to vitamin D-2 by ultraviolet light irradiation", J. Japan. Soc. Food Sci. Technol., Vol. 42, no 4, paginas 262-267, (1995), ISSN 0029-0394, (resumen), BIOSIS [en linea]. Philadelphia, PA (EE.UU.): BIOSIS, [recuperado el 10.04.2001]. Recuperado de: EPOQUE, E.P.O. (Holanda) No de acceso: PREV199598311933 *
NIWA K. et al.: "Anti-cancer effect in vitro and clinical efficacy of a cancer therapeutic containing natural herbs (BG-104), exposed to far infrared-ray heating and fermentation process using Aspergillus oryzae", Oyo Yakuri, Vol. 47, no 5, paginas 465-77, (1994), ISSN: 0300-8533, (resumen), HCAPLUS [en linea]. Columbus, OH (EE.UU.): Chemical Abstracts Service [recuperado el 10.04.2001]. Recuperado de: STN International, Columbus, OH (EE.UU.). No de acceso 1994:49737 *
NIWA K. et al.: "Tapering effects on glucocorticoids in autoimmune diseases by natural antioxidant and anti-cancer drug treated with infrared ray heating, fermentation and lipophilization", Oyo Yakuri, Vol. 54, no 4, paginas 227-233, (1997), ISSN: 0300-8533, (resumen), HCAPLUS [en linea]. Columbus, OH (EE.UU.): Chemical Abstracts Service [recuperado el 10.04.2001]. Recuperado de: STN International, Columbus, OH (EE.UU.). No de acceso 1997:774347 *

Also Published As

Publication number Publication date
NL1013049C2 (nl) 2002-01-11
CN1255376A (zh) 2000-06-07
FR2788697A1 (fr) 2000-07-28
ITTO990784A1 (it) 2001-03-14
SG76631A1 (en) 2000-11-21
GB2341800A (en) 2000-03-29
NO994463L (no) 2000-03-20
IS5183A (is) 2000-03-17
NO994463D0 (no) 1999-09-15
NL1019705A1 (nl) 2002-01-29
GB9921387D0 (en) 1999-11-10
GB9920710D0 (en) 1999-11-03
IL131722A0 (en) 2001-03-19
SE0100195L (sv) 2001-01-24
FR2783426A1 (fr) 2000-03-24
SE0100195D0 (sv) 2001-01-24
ES2155802B1 (es) 2001-12-01
SE9903307L (sv) 2000-03-18
NL1019705C2 (nl) 2002-03-26
IT1307267B1 (it) 2001-10-30
ITTO990784A0 (it) 1999-09-14
BE1012725A5 (fr) 2001-02-06
AU4486299A (en) 2000-03-30
SE9903307D0 (sv) 1999-09-16
ID23150A (id) 2000-03-23
NL1013049A1 (nl) 2000-03-21
CA2282234A1 (en) 2000-03-17
KR20000023206A (ko) 2000-04-25
JP2000159682A (ja) 2000-06-13
DK199901235A (da) 2000-03-18
DE19944695A1 (de) 2000-03-30

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