ES2159354T3 - Preparado en gel oftalmologico esteril aplicable en gotas, y procedimiento para su obtencion. - Google Patents

Preparado en gel oftalmologico esteril aplicable en gotas, y procedimiento para su obtencion.

Info

Publication number
ES2159354T3
ES2159354T3 ES96904826T ES96904826T ES2159354T3 ES 2159354 T3 ES2159354 T3 ES 2159354T3 ES 96904826 T ES96904826 T ES 96904826T ES 96904826 T ES96904826 T ES 96904826T ES 2159354 T3 ES2159354 T3 ES 2159354T3
Authority
ES
Spain
Prior art keywords
drops
procedure
obtaining
prepared
gel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96904826T
Other languages
English (en)
Inventor
Gunther Bellmann
Gudrun Claus-Herz
Hevia Cornelia Reimer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dr Gerhard Mann Chem Pharm Fabrik GmbH
Original Assignee
Dr Gerhard Mann Chem Pharm Fabrik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Gerhard Mann Chem Pharm Fabrik GmbH filed Critical Dr Gerhard Mann Chem Pharm Fabrik GmbH
Application granted granted Critical
Publication of ES2159354T3 publication Critical patent/ES2159354T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/78—Polymers containing oxygen of acrylic acid or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

LA INVENCION SE REFIERE A UNA PREPARACION OFTALMICA ESTERIL EN GOTAS, ESPECIALMENTE UNA PREPARACION DE GEL QUE TIENE UN FLUIDO VEHICULO O UNA BASE DE GEL BIFASICA QUE COMPRENDE UNA FASE ACUOSA LIQUIDA Y UNA FASE HIDROFOBA LIQUIDA.
ES96904826T 1995-03-28 1996-02-20 Preparado en gel oftalmologico esteril aplicable en gotas, y procedimiento para su obtencion. Expired - Lifetime ES2159354T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19511322A DE19511322C2 (de) 1995-03-28 1995-03-28 Sterile Augengele mit einem Gehalt an mittelkettigen Triglyceriden und Verfahren zu deren Herstellung

Publications (1)

Publication Number Publication Date
ES2159354T3 true ES2159354T3 (es) 2001-10-01

Family

ID=7757946

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96904826T Expired - Lifetime ES2159354T3 (es) 1995-03-28 1996-02-20 Preparado en gel oftalmologico esteril aplicable en gotas, y procedimiento para su obtencion.

Country Status (21)

Country Link
US (1) US6610318B1 (es)
EP (1) EP0817610B1 (es)
JP (2) JP3860609B2 (es)
KR (1) KR100384059B1 (es)
CN (1) CN1090476C (es)
AT (1) ATE201588T1 (es)
BR (1) BR9604878A (es)
CZ (1) CZ291002B6 (es)
DE (2) DE19511322C2 (es)
DK (1) DK0817610T3 (es)
ES (1) ES2159354T3 (es)
FI (1) FI119045B (es)
GR (1) GR3036418T3 (es)
HU (1) HU222108B1 (es)
NO (1) NO316664B1 (es)
NZ (1) NZ328774A (es)
PL (1) PL184695B1 (es)
PT (1) PT817610E (es)
SI (1) SI9620048A (es)
SK (1) SK281594B6 (es)
WO (1) WO1996029984A1 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
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JPH10218760A (ja) * 1997-02-04 1998-08-18 Nobel Igaku Kenkyusho:Kk ドライアイ治療用の微量油添加目薬
DE19938668B4 (de) * 1999-08-14 2006-01-26 Bausch & Lomb Inc. Tränenersatzmittel
AUPQ228199A0 (en) 1999-08-18 1999-09-09 Sly, Anthony William Ophthalmic fluid
AU2001231683A1 (en) * 2000-01-20 2001-07-31 Dr. Gerhard Mann Chem.-Pharm. Fabrik Gmbh Diclofenamide suspension gel
DE10132876A1 (de) * 2001-07-06 2003-01-30 Medproject Pharma Entwicklungs Zweiphasige, tropfbare Hydrogele zur Anwendung am Auge
FR2835748B1 (fr) * 2002-02-14 2007-06-15 Veyron Et Froment Lab Composition ophtalmique sous forme d'emulsion
CA2615108A1 (en) * 2005-07-13 2007-01-18 Santen Pharmaceutical Co., Ltd. Preservative composition for ophthalmic use
DE102005035986B4 (de) * 2005-07-28 2009-10-15 Bausch & Lomb Incorporated Steriles tropfbares mehrphasiges emulgatorfreies ophthalmisches Präparat
CN1883469B (zh) * 2006-05-26 2011-07-20 武汉远大制药集团有限公司 一种含有维生素a和维生素e的眼用微乳及其制备方法
DE102006049091A1 (de) * 2006-10-18 2008-04-24 Dr. Gerhard Mann Chem.-Pharm. Fabrik Gmbh Emulgatorfreies ophthalmisches Präparat enthaltend Pflanzenöl
GB2445539A (en) * 2006-12-29 2008-07-16 Ardana Bioscience Ltd Bigel composition
CN101028240B (zh) * 2007-03-29 2010-06-09 中国科学院上海药物研究所 眼用微乳/亚微乳原位凝胶制剂及其制备方法
FR2916636B1 (fr) 2007-05-29 2009-09-04 Octalia Technologies Vehicule sous forme d'une emulsion huile-dans-eau notamment destine a une utilisation ophtalmique ou dermocosmetique
US20120294898A1 (en) * 2011-05-19 2012-11-22 Warsaw Orthopedic, Inc. Injectable dbm for soft tissue repair
US8865685B2 (en) 2011-06-30 2014-10-21 Johnson & Johnson Vision Care, Inc. Esters for treatment of ocular inflammatory conditions
US11596599B2 (en) 2012-05-03 2023-03-07 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
KR102310775B1 (ko) 2012-05-03 2021-10-07 칼라 파마슈티컬스, 인크. 개선된 점막 수송을 나타내는 제약 나노입자
AU2013256064B2 (en) 2012-05-03 2018-01-04 Alcon Inc. Pharmaceutical nanoparticles showing improved mucosal transport
US9827191B2 (en) 2012-05-03 2017-11-28 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
EP3231417B1 (de) * 2016-04-15 2018-12-05 Dr. Gerhard Mann Chem.-Pharm. Fabrik GmbH Lagerungsstabile, ophthalmische zusammensetzung
ES3054066T3 (en) * 2017-06-09 2026-01-29 Omnivision Gmbh Composition for the treatment of dry eye
TW201916892A (zh) * 2017-07-26 2019-05-01 一般財團法人阪大微生物病研究會 經無菌化之黏稠性基劑之製造方法及醫藥製劑之製造方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE6466T1 (de) * 1979-10-26 1984-03-15 Smith And Nephew Associated Companies P.L.C. Autoklavierbare emulsionen.
JPS57171912A (en) * 1981-04-14 1982-10-22 Sumitomo Chem Co Ltd Cream
US4421748A (en) 1982-07-13 1983-12-20 Trager Seymour F Artificial tear aid
DE3440352A1 (de) * 1984-11-05 1986-05-07 Dr. Thilo & Co GmbH, 8029 Sauerlach Dry-eye-packung
JPS61130215A (ja) * 1984-11-28 1986-06-18 Santen Pharmaceut Co Ltd フルオロメトロンの水溶化方法
JPS61249918A (ja) * 1985-04-26 1986-11-07 Yutaka Mizushima 点眼剤
WO1988000824A1 (en) 1986-07-28 1988-02-11 Liposome Technology, Inc. Liposomes with enhanced retention on mucosal tissue
US5032392A (en) * 1986-09-04 1991-07-16 Vision Pharmaceuticals Aqueous ophthalmic solutions for the treatment of dryness and/or irritation of human or animal eyes
US4966773A (en) * 1986-11-25 1990-10-30 Alcon Laboratories, Inc. Topical ophthalmic compositions containing microfine retinoid particles
US4914088A (en) 1987-04-02 1990-04-03 Thomas Glonek Dry eye treatment solution and method
US4866049A (en) 1987-08-10 1989-09-12 Spectra Pharmaceutical Services, Inc. Ophthalmic compositionn and method of using same
LU87416A1 (fr) * 1988-12-29 1990-07-10 Cird Microgranules charges en une substance active,constitues essentiellement d'un triglyceride d'acides gras satures et leur utilisation par voie topique dans le domaine therapeutique
AU614465B2 (en) 1989-04-05 1991-08-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Medicinal emulsions
DE69115990T2 (de) 1990-05-29 1996-05-30 Ocular Res Of Bonton Inc Zusammensetzung zur Behandlung von Dry Eye Erkrankungen
US5252318A (en) 1990-06-15 1993-10-12 Allergan, Inc. Reversible gelation compositions and methods of use
IL98747A0 (en) * 1991-07-05 1992-07-15 Yissum Res Dev Co Ophthalmic compositions
FR2679135B1 (fr) * 1991-07-18 1995-05-19 Europhta Sa Laboratoire Nouvelles compositions ophtalmiques a adhesivite amelioree et leurs procedes de preparation.
JP3072340B2 (ja) * 1991-10-21 2000-07-31 ポーラ化成工業株式会社 水性目薬及びその製造法
FR2690846B1 (fr) 1992-05-05 1995-07-07 Aiache Jean Marc Forme galenique pour administration oculaire et procede de preparation.
EP0656779B1 (en) 1992-08-28 2000-04-12 Pharmos Corporation Submicron emulsions as ocular drug delivery vehicles
ATE194489T1 (de) * 1992-12-29 2000-07-15 Insite Vision Inc Bioerodierbares system zur kontrollierten freigabe
ES2141775T3 (es) 1993-04-16 2000-04-01 Wakamoto Pharma Co Ltd Composicion medicinal a base de agua termicamente gelificante reversible.
JP3438264B2 (ja) * 1993-07-07 2003-08-18 ライオン株式会社 安定なビタミンａ類可溶化水性点眼剤の調製方法
US5744155A (en) * 1993-08-13 1998-04-28 Friedman; Doron Bioadhesive emulsion preparations for enhanced drug delivery

Also Published As

Publication number Publication date
PT817610E (pt) 2001-11-30
NO974450D0 (no) 1997-09-26
CN1189773A (zh) 1998-08-05
HU222108B1 (hu) 2003-04-28
AU3928497A (en) 1999-05-10
JP4729364B2 (ja) 2011-07-20
FI119045B (fi) 2008-07-15
PL324620A1 (en) 1998-06-08
KR100384059B1 (ko) 2003-10-11
SK131497A3 (en) 1998-06-03
PL184695B1 (pl) 2002-12-31
BR9604878A (pt) 1999-11-30
JP2005325141A (ja) 2005-11-24
EP0817610B1 (de) 2001-05-30
AU722820B2 (en) 2000-08-10
NO316664B1 (no) 2004-03-29
SI9620048A (sl) 1998-04-30
HUP9801243A2 (hu) 1998-09-28
NZ328774A (en) 1999-09-29
HK1010941A1 (en) 1999-07-02
FI973797L (fi) 1997-09-26
DE19511322C2 (de) 1999-09-02
SK281594B6 (sk) 2001-05-10
WO1996029984A1 (de) 1996-10-03
EP0817610A1 (de) 1998-01-14
JPH10508316A (ja) 1998-08-18
CZ291002B6 (cs) 2002-11-13
CZ295297A3 (cs) 1998-03-18
ATE201588T1 (de) 2001-06-15
NO974450L (no) 1997-09-26
GR3036418T3 (en) 2001-11-30
FI973797A0 (fi) 1997-09-26
DE19511322A1 (de) 1996-10-02
DE59607005D1 (de) 2001-07-05
DK0817610T3 (da) 2001-09-10
HUP9801243A3 (en) 2001-03-28
JP3860609B2 (ja) 2006-12-20
KR19980703301A (ko) 1998-10-15
CN1090476C (zh) 2002-09-11
US6610318B1 (en) 2003-08-26

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