ES2161384T3 - Procedimiento para la preparacion de acidos n-acetil-d,l-alfa-aminocarboxilicos. - Google Patents

Procedimiento para la preparacion de acidos n-acetil-d,l-alfa-aminocarboxilicos.

Info

Publication number
ES2161384T3
ES2161384T3 ES96943039T ES96943039T ES2161384T3 ES 2161384 T3 ES2161384 T3 ES 2161384T3 ES 96943039 T ES96943039 T ES 96943039T ES 96943039 T ES96943039 T ES 96943039T ES 2161384 T3 ES2161384 T3 ES 2161384T3
Authority
ES
Spain
Prior art keywords
alpha
acetyl
acetylation
acids
aminocarboxylic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96943039T
Other languages
English (en)
Inventor
Karlheinz Drauz
Andreas Bommarius
Michael Karrenbauer
Gunter Knaup
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Evonik Operations GmbH
Original Assignee
Degussa GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa GmbH filed Critical Degussa GmbH
Application granted granted Critical
Publication of ES2161384T3 publication Critical patent/ES2161384T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/26—Separation; Purification; Stabilisation; Use of additives
    • C07C319/28—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/47—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/007—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

EN CONOCIDOS PROCESOS DE ACETILACION PARA LA PRODUCCION DE N ACETIL D, L AL ACIDOS AMINOCARBOXILICOS A PARTIR DE LOS CORRESPONDIENTES D, L AL ACIDOS AMINOCARBOXILICOS MEDIANTE LA ACETILACION CON ANHIDRIDO ACETICO EN ACIDO ACETICO Y EL AISLAMIENTO DE LOS N ACETIL D, L AL ACIDOS AMINOCARBOXILICOS RESUL TANTES DE LA MEZCLA DE ACETILACION, O BIEN SE PRODUCEN UNAS CANTIDADES MAS ELEVADAS DE SAL, O ES NECESARIO UN TRATAMIENTO ACUOSO PARA OBTENER N ACETILADOS AL ACIDOS AMINO DE SUFICIENTE PUREZA. REALIZANDO LA ACETILACION A 60 HASTA 150 C EN UNA CONCENTRACION < A 3 MOL DE AL ACIDO AMINOCARBOXILICO POR UN LIT RO DE ACIDO ACETICO (CONCENTRACION BAJO UNAS CONDICIONES ESTANDAR DE PRESION Y TEMPERATURA), OBTENIENDOSE EL N ACETIL D, L AL ACIDO AMINOCARBOXILICO MEDIANTE SU CONCENTRACION COMO CALDO DE FUSION O SOLIDO, PUEDE RENUNCIARSE POR ENTERO A REALIZAR UN TRATAMIENTO ACUOSO, CONSIGUIENDOSE A PESAR DE ELLO UNA ELEVADA CALIDAD TANTO EN LO QUE RESPECTA A RENDIMIENTO, COMO A PUREZA. LOS N ACETIL D, L ALACIDOS AMINOCARBOXILICOS PUEDEN SER UTILIZADOS EN EL DESDOBLAMIENTO ENZIMATICO DE UN PROCEDIMIENTO PARA LA PRODUCCION DE AL ACIDOS AMINOCARBOXILICOS OPTICAMENTE ACTIVOS.
ES96943039T 1995-12-13 1996-12-05 Procedimiento para la preparacion de acidos n-acetil-d,l-alfa-aminocarboxilicos. Expired - Lifetime ES2161384T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19546533A DE19546533C2 (de) 1995-12-13 1995-12-13 Verfahren zur Herstellung von N-Acetyl-D,L-alpha-aminocarbonsäuren

Publications (1)

Publication Number Publication Date
ES2161384T3 true ES2161384T3 (es) 2001-12-01

Family

ID=7780008

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96943039T Expired - Lifetime ES2161384T3 (es) 1995-12-13 1996-12-05 Procedimiento para la preparacion de acidos n-acetil-d,l-alfa-aminocarboxilicos.

Country Status (9)

Country Link
EP (1) EP0876329B1 (es)
JP (1) JP4001628B2 (es)
AT (1) ATE203232T1 (es)
AU (1) AU1190797A (es)
DE (2) DE19546533C2 (es)
DK (1) DK0876329T3 (es)
ES (1) ES2161384T3 (es)
PT (1) PT876329E (es)
WO (1) WO1997021667A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19749555A1 (de) * 1997-11-10 1999-05-12 Henkel Kgaa Enzymatisch-katalysierte N-Acylierung von Aminosäuren, Proteinhydrolysaten und/oder deren Derivaten
US8628684B2 (en) * 2009-05-20 2014-01-14 Basf Se Process for the preparation of a powder comprising one or more derivatives of glycine-N,N diacetic acid and/or one or more derivatives of glutamine-N,N diacetic acid and methylglycine-N,N diacetic acid trisodium salt powder
CN103408474B (zh) * 2013-08-28 2015-09-16 重庆紫光化工股份有限公司 高纯度n-乙酰-d,l-蛋氨酸的高效生产方法
EP3882256A4 (en) * 2018-11-12 2022-08-10 CJ Cheiljedang Corporation METHOD FOR PRODUCTION OF N-ACETYL DIPEPTIDE AND N-ACETYL AMINO ACID
CN116143648A (zh) * 2022-12-05 2023-05-23 河北远大九孚生物科技有限公司 一种n-乙酰-l-苯丙氨酸的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU753844A1 (ru) * 1978-01-10 1980-08-07 Научно-производственное объединение "Биохимреактив" Способ получени -ацетил- -валина

Also Published As

Publication number Publication date
DE59607329D1 (de) 2001-08-23
AU1190797A (en) 1997-07-03
WO1997021667A1 (de) 1997-06-19
PT876329E (pt) 2001-12-28
ATE203232T1 (de) 2001-08-15
EP0876329B1 (de) 2001-07-18
DE19546533C2 (de) 2000-04-27
DK0876329T3 (da) 2001-09-24
JP4001628B2 (ja) 2007-10-31
EP0876329A1 (de) 1998-11-11
DE19546533A1 (de) 1997-06-19
JP2000501387A (ja) 2000-02-08

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