ES2166043T3 - Uso de amlexanox en la preparacion de un medicamento para el tratamiento de ulceras aftosas. - Google Patents

Uso de amlexanox en la preparacion de un medicamento para el tratamiento de ulceras aftosas.

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Publication number
ES2166043T3
ES2166043T3 ES97202524T ES97202524T ES2166043T3 ES 2166043 T3 ES2166043 T3 ES 2166043T3 ES 97202524 T ES97202524 T ES 97202524T ES 97202524 T ES97202524 T ES 97202524T ES 2166043 T3 ES2166043 T3 ES 2166043T3
Authority
ES
Spain
Prior art keywords
amlexanox
treatment
alkyl
cyano
unsubstituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97202524T
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English (en)
Inventor
Kakubhai Rashmi Vora
Atul Khandwala
Charles G Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Block Drug Co Inc
Original Assignee
Block Drug Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Block Drug Co Inc filed Critical Block Drug Co Inc
Application granted granted Critical
Publication of ES2166043T3 publication Critical patent/ES2166043T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
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    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
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    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
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Abstract

EMPLEO DE AMLEXANOX, O UN HOMOLOGO O ANALOGO DE AMLEXANOX, PARA LA FABRICACION DE UNA COMPOSICION MEDICA PARA EL TRATAMIENTO DE ULCERAS AFTOSAS, CUYA FORMULA ES: DONDE R SUB,1} ES UN HIDROGENO, ALQUILO, FENILO, CARBOXILO, HIDROXILO, ALCOXILO, CARBOXIALQUILO COMO ESTERES, CIANO, ACILAMINO O AMINO QUE PUEDEN ESTAR SUSTITUIDOS O NO POR HASTA DOS GRUPOS ALQUILO; M ES 0, 1 O 2; R SUB,2} ES ALQUILO, ALQUENILO, ALCOXI, HALOGENO, NITRO, HIDROXI, CARBOXILO, BUTADIENILENO ( -CH = CH - CH = CH - ) QUE FORMA UN ANILLO BENCENO CON CUALQUIER ATOMO DE CARBONO ADYACENTE, CIANO, CARBOXIALQUILO, TRIFLUOROMETILO, O AMINO QUE PUEDEN ESTAR SUSTITUIDOS O NO POR AL MENOS UN GRUPO ALQUILO; Y R SUB,3} ES CARBOXILO, CIANO, ARILALCOXICARBONILO, ALCOXICARBONILO, O CARBOXIAMIDA, QUE PUEDEN ESTAR SUSTITUIDOS O NO POR AL MENOS UN GRUPO ALQUILO, Y LAS SALES DERIVADAS DEL MISMO.
ES97202524T 1991-04-09 1992-04-09 Uso de amlexanox en la preparacion de un medicamento para el tratamiento de ulceras aftosas. Expired - Lifetime ES2166043T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68234791A 1991-04-09 1991-04-09

Publications (1)

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ES2166043T3 true ES2166043T3 (es) 2002-04-01

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ID=24739298

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ES97202524T Expired - Lifetime ES2166043T3 (es) 1991-04-09 1992-04-09 Uso de amlexanox en la preparacion de un medicamento para el tratamiento de ulceras aftosas.

Country Status (8)

Country Link
EP (2) EP0836852B1 (es)
JP (1) JPH0597706A (es)
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GB9707934D0 (en) 1997-04-18 1997-06-04 Danbiosyst Uk Improved delivery of drugs to mucosal surfaces
WO1999027905A1 (en) 1997-12-02 1999-06-10 West Pharmaceutical Services Drug Delivery & Clinical Research Centre Limited Compositions for nasal administration
US6432415B1 (en) 1999-12-17 2002-08-13 Axrix Laboratories, Inc. Pharmaceutical gel and aerosol formulations and methods to administer the same to skin and mucosal surfaces
AR029489A1 (es) 2000-03-10 2003-07-02 Euro Celtique Sa Piridinas, pirimidinas, pirazinas, triazinas sustituidas por arilo, composiciones farmaceuticas y el uso de las mismas para la manufactura de un medicamento
AR036873A1 (es) 2001-09-07 2004-10-13 Euro Celtique Sa Piridinas aril sustituidas a, composiciones farmaceuticas y el uso de las mismas para la preparacion de un medicamento
AR037233A1 (es) 2001-09-07 2004-11-03 Euro Celtique Sa Piridinas aril sustituidas, composiciones farmaceuticas y el uso de dichos compuestos para la elaboracion de un medicamento
GB0300531D0 (en) 2003-01-10 2003-02-12 West Pharm Serv Drug Res Ltd Pharmaceutical compositions
GB0414803D0 (en) * 2004-07-01 2004-08-04 Glaxo Group Ltd Composition
WO2014071203A1 (en) * 2012-11-02 2014-05-08 University Of Kentucky Research Foundation Sustained release of topical anesthetics
EP3544570B1 (en) * 2016-12-27 2020-12-02 Colgate-Palmolive Company Oral care product and methods of use and manufacture thereof

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US4255576A (en) * 1977-03-08 1981-03-10 Takeda Chemical Industries, Ltd. 1-Azaxanthone derivatives
US4228173A (en) * 1978-08-15 1980-10-14 Fisons Limited Thiopyrano-benzopyrans, compositions and method of use thereof
IT1232252B (it) * 1989-02-22 1992-01-28 Rotta Research Lab Derivati della n fenil benzamide ad attivita' antiulcera ed antiallerica e procedimento per la loro preparazione
EP1078629A3 (en) * 1989-09-07 2001-05-23 Glaxo Group Limited Use of Salmeterol and salts for the treatment of inflammation and allergy

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DE69232143D1 (de) 2001-11-22
DE69232143T2 (de) 2002-06-06
ATE206922T1 (de) 2001-11-15
EP0518798A3 (en) 1994-12-07
PT836852E (pt) 2002-02-28
EP0836852B1 (en) 2001-10-17
EP0836852A1 (en) 1998-04-22
CA2065496A1 (en) 1992-10-10
CA2065496C (en) 2003-03-25
EP0518798A2 (en) 1992-12-16
DK0836852T3 (da) 2001-11-19
JPH0597706A (ja) 1993-04-20

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