ES2172573T3 - Hidrogel basado en albumina. - Google Patents

Hidrogel basado en albumina.

Info

Publication number
ES2172573T3
ES2172573T3 ES95901297T ES95901297T ES2172573T3 ES 2172573 T3 ES2172573 T3 ES 2172573T3 ES 95901297 T ES95901297 T ES 95901297T ES 95901297 T ES95901297 T ES 95901297T ES 2172573 T3 ES2172573 T3 ES 2172573T3
Authority
ES
Spain
Prior art keywords
novel
hydrogels
novel hydrogels
albumin
bifunctionalyzed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95901297T
Other languages
English (en)
Inventor
Guy Fortier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioartificial Gel Technologies Inc
Original Assignee
Bioartificial Gel Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioartificial Gel Technologies Inc filed Critical Bioartificial Gel Technologies Inc
Application granted granted Critical
Publication of ES2172573T3 publication Critical patent/ES2172573T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041—Lenses
    • G02B1/043—Contact lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/26—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/60—Liquid-swellable gel-forming materials, e.g. super-absorbents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075—Macromolecular gels
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Biochemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)

Abstract

HIDROGELES BIOARTIFICIALES NOVEDOSOS QUE CONSTAN DE UNA MEZCLA RETICULADA TRIDIMENSIONAL DE: (A) UN OXIDO DE POLIETILENO BIFUNCIONALIZADO, ACTIVADO CON UN AGENTE ACTIVANTE, DISUELTO EN UNA SOLUCION ACUOSA; Y (B) PROTEINA DEL TIPO ALBUMINA. LOS HIDROGELES NOVEDOSOS SE BASAN EN LA RETICULACION DE LA PROTEINA ALBUMINA DE VARIAS FUENTES QUE INCLUYEN, POR EJEMPLO, UNA ALBUMINA DE SERUM BOBINO, LACTALBUMINA O VALBUMINA CON UN OXIDO DE POLIETILENO BIFUNCIONALIZADO, MAS PREFERIBLEMENTE GLICOL POLIETILENO, O UNA MEZCLA DE OXIDOS DE POLIETILENO BIFUNCIONALIZADOS PREFERIBLEMENTE GLICOL POLIETILENO, O VARIAS MASAS MOLECULARES (MR 2000 A 35000), DISUELTAS EN UNA SOLUCION ACUOSA EN PROPORCIONES ADECUADAS. TAMBIEN SE PROPORCIONA UN METODO Y CONDICIONES PARA PREPARAR LOS HIDROGELES NOVEDOSOS. TAMBIEN SE DIVULGAN UNA VARIEDAD DE APLICACIONES BIOMEDICAS PARA LOS HIDROGELES NOVEDOSOS. ADICIONALMENTE, SE HA DESCUBIERTO QUE LAS PROPIEDADES MECANICAS DE ESTOS HIDROGELES PUEDEN MEJORARSE AÑADIENDO A LA SOLUCION DE MOLDEADO UN GLICOL POLIETILENO NO REACTIVO U OTRO POLIMERO INERTE DE MASAS MOLECULARES ELEVADAS (MR > 10000). EN TERMINOS GENERALES, LOS HIDROGELES NOVEDOSOS POSEEN PROPIEDADES VENTAJOSAS TALES COMO LA RETENCION Y MEMORIA DE FORMA, UN CONTENIDO ELEVADO EN AGUA (MAS DEL 94% (W/W) BASADOS EN EL PESO SECO DE HIDROGEL), BUENAS PROPIEDADES MECANICAS Y OPTICAS. LOS HIDROGELES EXHIBEN CARACTERISTICAS ADICIONALES QUE PUEDEN HACERLOS EXTREMADAMENTE UTILES EN LAS AREAS FARMACEUTICA Y MEDICA DEBIDO A SUS PROPIEDADES VENTAJOSAS TALES COMO LA BIOCOMPATIBILIDAD, RESISTENCIA A LA ACCION DE LAS PROTEASAS, LIBERACION LENTA DE VARIOS MEDICAMENTOS, SUPERFICIE HIDROFILICA, UNA BUENA PERMEABILIDAD AL OXIGENO Y UNA POROSIDAD CONTROLADA.
ES95901297T 1993-12-01 1994-11-24 Hidrogel basado en albumina. Expired - Lifetime ES2172573T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15955993A 1993-12-01 1993-12-01

Publications (1)

Publication Number Publication Date
ES2172573T3 true ES2172573T3 (es) 2002-10-01

Family

ID=22573064

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95901297T Expired - Lifetime ES2172573T3 (es) 1993-12-01 1994-11-24 Hidrogel basado en albumina.

Country Status (9)

Country Link
US (1) US5733563A (es)
EP (1) EP0705298B1 (es)
AT (1) ATE215106T1 (es)
AU (1) AU1060495A (es)
DE (1) DE69430243T2 (es)
DK (1) DK0705298T3 (es)
ES (1) ES2172573T3 (es)
PT (1) PT705298E (es)
WO (1) WO1995015352A1 (es)

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* Cited by examiner, † Cited by third party
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US5733563A (en) 1998-03-31
EP0705298B1 (en) 2002-03-27
EP0705298A1 (en) 1996-04-10
DE69430243T2 (de) 2002-10-17
WO1995015352A1 (en) 1995-06-08
ATE215106T1 (de) 2002-04-15
DK0705298T3 (da) 2002-07-08
PT705298E (pt) 2002-07-31
AU1060495A (en) 1995-06-19
DE69430243D1 (de) 2002-05-02

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