ES2173300T3 - Vacunas de virus vivos prrs de baja patogenicidad y metodos para su preparacion. - Google Patents

Vacunas de virus vivos prrs de baja patogenicidad y metodos para su preparacion.

Info

Publication number
ES2173300T3
ES2173300T3 ES96922508T ES96922508T ES2173300T3 ES 2173300 T3 ES2173300 T3 ES 2173300T3 ES 96922508 T ES96922508 T ES 96922508T ES 96922508 T ES96922508 T ES 96922508T ES 2173300 T3 ES2173300 T3 ES 2173300T3
Authority
ES
Spain
Prior art keywords
vaccines
living
preparation
methods
low pathogenicity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96922508T
Other languages
English (en)
Inventor
Han Soo Joo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Minnesota Twin Cities
University of Minnesota System
Original Assignee
University of Minnesota Twin Cities
University of Minnesota System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Minnesota Twin Cities, University of Minnesota System filed Critical University of Minnesota Twin Cities
Application granted granted Critical
Publication of ES2173300T3 publication Critical patent/ES2173300T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Reproductive Health (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

SE APORTAN VACUNAS PRRS VIVAS O VIVAS MODIFICADAS PARA SU ADMINISTRACION A CERDOS, QUE POSEEN BAJA VIRULENCIA Y CONFIEREN INMUNIDAD EFECTIVA CONTRA PRRS. LAS VACUNAS PREFERIDAS INCLUYEN AISLADOS DE VIRUS CON UN PROMEDIO DE DIAMETROS DE PLACA DE MENOS DE UNOS 2 MM Y BAJA PATOGENICIDAD. UNA VACUNA PREFERIDA INCLUYE UNA CEPA DE PEQUEÑO DIAMETRO DE PLACA, ATCC ACCESION NO. VR2509. LAS VACUNAS DE LA INVENCION PUEDEN ADMINISTRARSE A HEMBRAS CRIANDO O A CERDAS PRIMIPARAS Y A LECHONES DESTETADOS, Y ES EFECTIVA PARA INMUNIZAR AL CERDO TANTO CONTRA LA FORMA RESPIRATORIA COMO REPRODUCTIVA DE LA ENFERMEDAD.
ES96922508T 1995-06-21 1996-06-19 Vacunas de virus vivos prrs de baja patogenicidad y metodos para su preparacion. Expired - Lifetime ES2173300T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/493,265 US5690940A (en) 1995-06-21 1995-06-21 Low pathogencity PRRS live virus vaccines and methods of preparation thereof

Publications (1)

Publication Number Publication Date
ES2173300T3 true ES2173300T3 (es) 2002-10-16

Family

ID=23959539

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96922508T Expired - Lifetime ES2173300T3 (es) 1995-06-21 1996-06-19 Vacunas de virus vivos prrs de baja patogenicidad y metodos para su preparacion.

Country Status (20)

Country Link
US (1) US5690940A (es)
EP (1) EP0833661B1 (es)
JP (1) JP4709094B2 (es)
KR (1) KR100444809B1 (es)
CN (1) CN1126569C (es)
AT (1) ATE215384T1 (es)
AU (1) AU703084B2 (es)
BR (1) BR9608648A (es)
CA (1) CA2225388C (es)
CZ (1) CZ291611B6 (es)
DE (1) DE69620402T2 (es)
DK (1) DK0833661T3 (es)
ES (1) ES2173300T3 (es)
HU (1) HU227754B1 (es)
PL (1) PL184231B1 (es)
PT (1) PT833661E (es)
RU (1) RU2192887C2 (es)
SK (1) SK281024B6 (es)
UA (1) UA47433C2 (es)
WO (1) WO1997000696A1 (es)

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CA2290906C (en) * 1991-06-06 2003-04-01 Stichting Centraal Diergeneeskundig Instituut Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits
JP3135069B2 (ja) * 1996-03-01 2001-02-13 シェーリング コーポレイション ブタ生殖および呼吸症候群ワクチン
US5866401A (en) * 1996-03-01 1999-02-02 Schering Corporation Porcine reproductive and respiratory syndrome vaccine
US20040224327A1 (en) * 1996-10-30 2004-11-11 Meulenberg Johanna Jacoba Maria Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
EP0839912A1 (en) * 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
ID23399A (id) 1997-05-06 2000-04-20 Stichting Dienst Landbouwkundi Situs antigenik prrsv untuk mengidentifikasi urutan peptida dari virus prrs yang digunakan untuk vaksin atau pengujian diagnostik
CA2366072C (en) * 1999-03-08 2007-07-10 Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. Prrsv vaccines
ES2348159T3 (es) * 1999-04-22 2010-11-30 United States Department Of Agriculture Vacuna contra el sindrome respiratorio y reproductivo porcino basada en el aislado ja-142.
SG83740A1 (en) * 1999-08-10 2001-10-16 Inst Of Molecular Agrobiology An attenuated porcine reproductive and respiratory syndrome virus strain and methods of use
TW200604526A (en) * 2004-06-18 2006-02-01 Unviersity Of Minnesota Identifying virally infected and vaccinated organisms
US7632636B2 (en) * 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
PT2369001T (pt) 2005-06-24 2016-10-25 Univ Minnesota Vírus srrp, clones infecciosos, os seus mutantes e processos de utilização
US7241582B2 (en) * 2005-07-05 2007-07-10 Mj Biologics, Inc. Diagnostic test kits
RU2316346C2 (ru) * 2006-02-20 2008-02-10 Федеральное государственное учреждение "Федеральный центр охраны здоровья животных" (ФГУ "ВНИИЗЖ") Вакцина против репродуктивно-респираторного синдрома свиней эмульсионная инактивированная
CN101848995A (zh) * 2007-06-25 2010-09-29 南达科他州立大学 重组的北美1型猪繁殖与呼吸综合征病毒及使用方法
KR101653177B1 (ko) * 2008-08-25 2016-09-01 베링거잉겔하임베트메디카인코퍼레이티드 고병원성 돼지 생식기 및 호흡기 증후군(ｈｐ ｐｒｒｓ)에 대한 백신
US9050317B2 (en) 2008-10-31 2015-06-09 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US8409376B2 (en) 2008-10-31 2013-04-02 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8725420B2 (en) 2008-10-31 2014-05-13 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US9060926B2 (en) 2008-10-31 2015-06-23 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US9060931B2 (en) 2008-10-31 2015-06-23 The Invention Science Fund I, Llc Compositions and methods for delivery of frozen particle adhesives
US8788211B2 (en) 2008-10-31 2014-07-22 The Invention Science Fund I, Llc Method and system for comparing tissue ablation or abrasion data to data related to administration of a frozen particle composition
US8603495B2 (en) 2008-10-31 2013-12-10 The Invention Science Fund I, Llc Compositions and methods for biological remodeling with frozen particle compositions
US9060934B2 (en) 2008-10-31 2015-06-23 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8731840B2 (en) 2008-10-31 2014-05-20 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US9050070B2 (en) 2008-10-31 2015-06-09 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8731841B2 (en) 2008-10-31 2014-05-20 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US8563012B2 (en) 2008-10-31 2013-10-22 The Invention Science Fund I, Llc Compositions and methods for administering compartmentalized frozen particles
US8721583B2 (en) 2008-10-31 2014-05-13 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8551505B2 (en) 2008-10-31 2013-10-08 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US9072688B2 (en) 2008-10-31 2015-07-07 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US8793075B2 (en) 2008-10-31 2014-07-29 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US8414356B2 (en) 2008-10-31 2013-04-09 The Invention Science Fund I, Llc Systems, devices, and methods for making or administering frozen particles
US8762067B2 (en) 2008-10-31 2014-06-24 The Invention Science Fund I, Llc Methods and systems for ablation or abrasion with frozen particles and comparing tissue surface ablation or abrasion data to clinical outcome data
US8221480B2 (en) 2008-10-31 2012-07-17 The Invention Science Fund I, Llc Compositions and methods for biological remodeling with frozen particle compositions
US20100111857A1 (en) 2008-10-31 2010-05-06 Boyden Edward S Compositions and methods for surface abrasion with frozen particles
US20100111835A1 (en) * 2008-10-31 2010-05-06 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Compositions and methods for therapeutic delivery with frozen particles
US9056047B2 (en) 2008-10-31 2015-06-16 The Invention Science Fund I, Llc Compositions and methods for delivery of frozen particle adhesives
US8568363B2 (en) 2008-10-31 2013-10-29 The Invention Science Fund I, Llc Frozen compositions and methods for piercing a substrate
US8603494B2 (en) 2008-10-31 2013-12-10 The Invention Science Fund I, Llc Compositions and methods for administering compartmentalized frozen particles
US8545855B2 (en) 2008-10-31 2013-10-01 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US9072799B2 (en) 2008-10-31 2015-07-07 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
TWI627281B (zh) * 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 降低ｐｃｖ－２組合物殺病毒活性之方法及具有改良免疫原性之ｐｃｖ－２組合物
US8541482B2 (en) * 2009-10-05 2013-09-24 Creative Nail Design, Inc. Removable multilayer nail coating system and methods therefore
US8263677B2 (en) 2009-09-08 2012-09-11 Creative Nail Design, Inc. Removable color gel basecoat for artificial nail coatings and methods therefore
US8492454B2 (en) * 2009-10-05 2013-07-23 Creative Nail Design, Inc. Removable color layer for artificial nail coatings and methods therefore
ES2692809T3 (es) 2011-02-17 2018-12-05 Boehringer Ingelheim Vetmedica Gmbh Nueva cepa del PRRSV europea
CA2827337C (en) 2011-02-17 2019-07-09 Boehringer Ingelheim Vetmedica Gmbh Commercial scale process for production of prrsv
EP2683350A4 (en) 2011-03-07 2015-08-05 Creative Nail Design Inc UV CURABLE NAILS COSMETIC COATING COMPOSITIONS AND RELATED METHODS
KR101281361B1 (ko) 2011-07-18 2013-07-02 서울대학교산학협력단 북미형 돼지 생식기 호흡기 증후군 바이러스 예방 백신 조성물 및 이를 포함하는 혼합백신 조성물
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
US9315781B2 (en) 2011-07-29 2016-04-19 Boehringer Ingelheim Vetmedica Gmbh Infectious CDNA clone of european PRRS virus and uses thereof
CN105308178B (zh) 2012-12-07 2019-06-07 伊利诺伊大学评议会 猪繁殖与呼吸综合征病毒组合物及其用途
US9579373B2 (en) 2013-03-15 2017-02-28 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use
US10279031B2 (en) 2016-05-11 2019-05-07 Phibro Animal Health Corporation Composition comprising antigens and a mucosal adjuvant and a method for using

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US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
NZ261992A (en) * 1993-02-08 1996-06-25 Bayer Ag Porcine reproductive and respiratory syndrome virus, cultures, attenuated forms and vaccines thereof
ES2074950B1 (es) * 1993-09-17 1996-03-16 Iberica Cyanamid Vacuna para la prevencion de la enfermedad reproductiva y respiratoria de la cerda.

Also Published As

Publication number Publication date
DE69620402D1 (de) 2002-05-08
WO1997000696A1 (en) 1997-01-09
CZ412797A3 (cs) 1998-05-13
JPH11509087A (ja) 1999-08-17
PT833661E (pt) 2002-08-30
DE69620402T2 (de) 2002-11-07
CA2225388A1 (en) 1997-01-09
UA47433C2 (uk) 2002-07-15
EP0833661A1 (en) 1998-04-08
CZ291611B6 (cs) 2003-04-16
KR19990022848A (ko) 1999-03-25
CA2225388C (en) 2010-03-23
HUP9903169A2 (hu) 2000-01-28
ATE215384T1 (de) 2002-04-15
US5690940A (en) 1997-11-25
EP0833661B1 (en) 2002-04-03
AU6336196A (en) 1997-01-22
PL184231B1 (pl) 2002-09-30
EP0833661A4 (en) 1998-10-21
RU2192887C2 (ru) 2002-11-20
SK165797A3 (en) 1998-05-06
HUP9903169A3 (en) 2001-06-28
HU227754B1 (en) 2012-02-28
HK1016870A1 (en) 1999-11-12
KR100444809B1 (ko) 2004-11-06
MX9710149A (es) 1998-07-31
JP2006306894A (ja) 2006-11-09
AU703084B2 (en) 1999-03-18
CN1188417A (zh) 1998-07-22
JP4709094B2 (ja) 2011-06-22
JP3954101B2 (ja) 2007-08-08
SK281024B6 (sk) 2000-11-07
CN1126569C (zh) 2003-11-05
DK0833661T3 (da) 2002-05-06
BR9608648A (pt) 1999-12-07
PL324204A1 (en) 1998-05-11

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