ES2175804T3 - Nuevas pirimidin-4-ona y primidin-4-tiona como fungicida. - Google Patents

Nuevas pirimidin-4-ona y primidin-4-tiona como fungicida.

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Publication number
ES2175804T3
ES2175804T3 ES98951380T ES98951380T ES2175804T3 ES 2175804 T3 ES2175804 T3 ES 2175804T3 ES 98951380 T ES98951380 T ES 98951380T ES 98951380 T ES98951380 T ES 98951380T ES 2175804 T3 ES2175804 T3 ES 2175804T3
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ES
Spain
Prior art keywords
carbon atoms
alkyl
halogen
substituted
mono
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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ES98951380T
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English (en)
Inventor
Harald Walter
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Syngenta Participations AG
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Syngenta Participations AG
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/541,3-Diazines; Hydrogenated 1,3-diazines
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88Oxygen atoms
    • C07D239/90Oxygen atoms with acyclic radicals attached in position 2 or 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88Oxygen atoms
    • C07D239/91Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88Oxygen atoms
    • C07D239/92Oxygen atoms with hetero atoms directly attached to nitrogen atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/28Halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30Hetero atoms other than halogen
    • C07D333/36Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Pest Control & Pesticides (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Un compuesto de la fórmula I **fórmula** en el que A es tienilo, tiazolilo, piridilo o piridazinilo; X es oxígeno o azufre; R1 es hidrógeno, halógeno o trimetilsililo; R2 es hidrógeno, halógeno o trimetilsililo; al menos uno de R1 y R2 no es hidrógeno; R3 esalquilode1 a 8 átomos de carbono,alquenilo de1 a 8 átomos de carbono, alquinilo de 1 a 8 átomos de carbono que no están sustituidos o están de monoa tri-sustituidos por cicloalquilo de 3 a 6 átomos de carbono, halógeno, alcoxi de 1a6átomos de carbono o haloalcoxi de 1 a 6 átomos de carbono; O-alquilo(de 1 a 6 átomos de carbono), O-alquenilo(de 2 a 6 átomos de carbono), O-alquinilo(de 2 a 6 átomos de carbono), que no están sustituidos o están de monoa tri-sustituidos por cicloalquilo de 3 a 6 átomos de carbono, halógeno o alcoxi de1 a 6 átomos de carbono;N-alquilo(de1 a 6 átomos de carbono); o N=CH-alquilo(de 1 a 6 átomos de carbono); R4 es alquilo de 1 a 8 átomos de carbono, alquenilo de 1 a 8 átomos de carbono, alquinilo de 1 a 8 átomosde carbono que no están sustituidos o están de monoa tri-sustituidos por cicloalquilo de 3 a 6 átomos de carbono, halógeno, ciano, alcoxi de1a 6átomosdecarbonoohaloalcoxide1 a 6 átomos de carbono; nitro;-CO-alquilo(de1 a 6 átomosdecarbono);cicloalquilode3 a 6 átomos de carbono; o fenilo, que no está sustituido o está de monoa tri-sustituido por halógeno, alquilo de 1 a 6 átomos de carbono, haloalquilo de 1 a 6 átomos de carbono,alcoxi de1 a 6 átomos de carbono,haloalcoxi de1 a 6 átomos de carbono, ciano, nitro, amino, mono-alquil(de 1 a 6 átomos de carbono)-amino, di-alquil(de 1 a 6 átomos de carbono)-amino, alquil(de 1 a 6 átomos de carbono)-tio, fenilo o fenoxi y en el que la parte fenílica no está sustituida o está de monoa tri-sustituida por halógeno, alquilo de 1 a 6 átomos de carbono, haloalquilo de 1 a 6 átomos de carbono, alcoxi de 1 a 6 átomos de carbono o haloalcoxi de 1 a 6 átomos de carbono.
ES98951380T 1997-09-12 1998-09-10 Nuevas pirimidin-4-ona y primidin-4-tiona como fungicida. Expired - Lifetime ES2175804T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9719411.2A GB9719411D0 (en) 1997-09-12 1997-09-12 New Pesticides

Publications (1)

Publication Number Publication Date
ES2175804T3 true ES2175804T3 (es) 2002-11-16

Family

ID=10818960

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98951380T Expired - Lifetime ES2175804T3 (es) 1997-09-12 1998-09-10 Nuevas pirimidin-4-ona y primidin-4-tiona como fungicida.

Country Status (26)

Country Link
US (1) US6277858B1 (es)
EP (1) EP1015434B1 (es)
JP (1) JP2001516749A (es)
KR (1) KR100585571B1 (es)
CN (1) CN1270593A (es)
AR (1) AR015439A1 (es)
AT (1) ATE216370T1 (es)
AU (1) AU743717B2 (es)
BR (1) BR9812439A (es)
CA (1) CA2301694A1 (es)
DE (1) DE69804981T2 (es)
DK (1) DK1015434T3 (es)
EG (1) EG22051A (es)
ES (1) ES2175804T3 (es)
GB (1) GB9719411D0 (es)
GT (1) GT199800142A (es)
HN (1) HN1998000139A (es)
HU (1) HUP0002423A3 (es)
IL (1) IL134779A0 (es)
NZ (1) NZ503261A (es)
PL (1) PL339053A1 (es)
PT (1) PT1015434E (es)
TR (1) TR200000713T2 (es)
TW (1) TW429254B (es)
WO (1) WO1999014202A2 (es)
ZA (1) ZA988336B (es)

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JP2001524121A (ja) * 1997-05-08 2001-11-27 アグレボ・ユー・ケイ・リミテツド 殺菌剤
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GT199900185A (es) 1998-11-06 2001-04-18 Novedosa pirimidin-4-enamina como fungicida.
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KR100967280B1 (ko) * 2002-06-11 2010-07-01 이 아이 듀폰 디 네모아 앤드 캄파니 흰가루병을 방제하는데 유용한 융합된 피리미디논과디니트로페놀 화합물의 혼합물
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US8420673B2 (en) 2007-01-25 2013-04-16 E I Du Pont De Nemours And Company Fungicidal amides
DE102007045920B4 (de) 2007-09-26 2018-07-05 Bayer Intellectual Property Gmbh Synergistische Wirkstoffkombinationen
CN101970432B (zh) 2008-01-25 2014-05-28 杜邦公司 杀真菌杂环化合物
CN101531638B (zh) * 2008-03-13 2011-12-28 中国科学院广州生物医药与健康研究院 用作雌激素相关受体调节剂的化合物及其应用
CN101628913B (zh) 2008-07-18 2013-01-23 中国科学院广州生物医药与健康研究院 用作雌激素相关受体调节剂的化合物及其应用
TW201036966A (en) 2008-12-02 2010-10-16 Du Pont Fungicidal heterocyclic compounds
AR075713A1 (es) 2009-03-03 2011-04-20 Du Pont Pirazoles fungicidas
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CN102548969A (zh) 2009-08-07 2012-07-04 杜邦公司 杀真菌的二苯基取代哒嗪
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KR20120112755A (ko) 2010-01-07 2012-10-11 이 아이 듀폰 디 네모아 앤드 캄파니 살진균제 복소환 화합물
CN102285971B (zh) * 2010-06-21 2013-12-18 中国中化股份有限公司 吡唑基喹唑啉酮类化合物及其应用
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CN103130730B (zh) * 2011-11-24 2015-04-08 南开大学 喹唑啉类衍生物及其制备方法、抗hiv活性和抗tmv活性
CN104151255B (zh) * 2014-07-22 2016-07-13 清华大学 一种多取代喹唑啉亚胺衍生物及其制备方法
EP2910126A1 (en) 2015-05-05 2015-08-26 Bayer CropScience AG Active compound combinations having insecticidal properties
SG11201804901WA (en) 2015-12-22 2018-07-30 SHY Therapeutics LLC Compounds for the treatment of cancer and inflammatory disease
CN109195974A (zh) 2016-06-02 2019-01-11 拜耳作物科学股份公司 异噻唑并吡啶酮、其制备方法及其用作除草剂和/或植物生长调节剂的用途
WO2017207395A1 (en) 2016-06-02 2017-12-07 Bayer Cropscience Aktiengesellschaft Isothiazolopyridones, processes for their preparation and their use as fungicides
PL3529246T3 (pl) 2016-10-24 2024-03-25 Fmc Corporation Oksadiazole o działaniu grzybobójczym
EA201992780A1 (ru) 2017-06-21 2020-06-02 ШАЙ ТЕРАПЬЮТИКС ЭлЭлСи Соединения, которые взаимодействуют с суперсемейством ras, для лечения рака, воспалительных заболеваний, ras-опатий и фиброзного заболевания
US12391705B2 (en) 2018-12-19 2025-08-19 Shy Therapeutics, Llc Compounds that interact with the Ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease

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JP2001524121A (ja) * 1997-05-08 2001-11-27 アグレボ・ユー・ケイ・リミテツド 殺菌剤

Also Published As

Publication number Publication date
TW429254B (en) 2001-04-11
WO1999014202A3 (en) 1999-05-14
CN1270593A (zh) 2000-10-18
DK1015434T3 (da) 2002-08-05
BR9812439A (pt) 2000-09-26
CA2301694A1 (en) 1999-03-25
TR200000713T2 (tr) 2000-08-21
KR100585571B1 (ko) 2006-06-02
NZ503261A (en) 2002-03-28
US6277858B1 (en) 2001-08-21
EG22051A (en) 2002-06-30
PL339053A1 (en) 2000-12-04
WO1999014202B1 (en) 1999-06-17
JP2001516749A (ja) 2001-10-02
HN1998000139A (es) 1999-06-02
EP1015434A2 (en) 2000-07-05
HUP0002423A3 (en) 2001-02-28
DE69804981T2 (de) 2002-11-28
AR015439A1 (es) 2001-05-02
ZA988336B (en) 1999-02-12
IL134779A0 (en) 2001-04-30
EP1015434B1 (en) 2002-04-17
KR20010023894A (ko) 2001-03-26
AU743717B2 (en) 2002-01-31
GT199800142A (es) 2000-03-02
DE69804981D1 (de) 2002-05-23
AU9742998A (en) 1999-04-05
PT1015434E (pt) 2002-08-30
ATE216370T1 (de) 2002-05-15
HUP0002423A2 (hu) 2000-11-28
WO1999014202A2 (en) 1999-03-25
GB9719411D0 (en) 1997-11-12

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