ES2176565T3 - Agente auxiliar para la formacion directa de comprimidos. - Google Patents

Agente auxiliar para la formacion directa de comprimidos.

Info

Publication number
ES2176565T3
ES2176565T3 ES97111490T ES97111490T ES2176565T3 ES 2176565 T3 ES2176565 T3 ES 2176565T3 ES 97111490 T ES97111490 T ES 97111490T ES 97111490 T ES97111490 T ES 97111490T ES 2176565 T3 ES2176565 T3 ES 2176565T3
Authority
ES
Spain
Prior art keywords
tablets
auxiliary agent
direct training
weight
direct
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97111490T
Other languages
English (en)
Inventor
Karl Dr Kolter
Siegfried Dr Lang
Peter Prof Schmidt
Anja Huhne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Application granted granted Critical
Publication of ES2176565T3 publication Critical patent/ES2176565T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PRODUCTO AUXILIAR PARA EL TABLETAJE DIRECTO QUE CONTIENE A) DE UN 75 A UN 98 % EN PESO DE UNA CELULOSA PULVERULENTA APTA PARA EL TABLETAJE B) DE UN 1 A UN 15 % EN PESO DE POLIVINILPIRROLIDONA SOLUBLE C) DE UN 0,5 A UN 10 % EN PESO DE POLIVINILPIRROLIDONA NO SOLUBLE Y RETICULADA.
ES97111490T 1996-07-16 1997-07-08 Agente auxiliar para la formacion directa de comprimidos. Expired - Lifetime ES2176565T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19628617A DE19628617A1 (de) 1996-07-16 1996-07-16 Direkttablettierhilfsmittel

Publications (1)

Publication Number Publication Date
ES2176565T3 true ES2176565T3 (es) 2002-12-01

Family

ID=7799949

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97111490T Expired - Lifetime ES2176565T3 (es) 1996-07-16 1997-07-08 Agente auxiliar para la formacion directa de comprimidos.

Country Status (6)

Country Link
US (1) US5840769A (es)
EP (1) EP0819429B1 (es)
JP (1) JPH1067651A (es)
CN (1) CN1174775C (es)
DE (2) DE19628617A1 (es)
ES (1) ES2176565T3 (es)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2159419C (en) * 1994-10-17 2006-07-04 Pieter De Haan Solid pharmaceutical composition comprising an excipient capable of binding water
IT1301966B1 (it) 1998-07-30 2000-07-20 Zambon Spa Composizioni farmaceutiche ad attivita' analgesica
SE9802973D0 (sv) * 1998-09-03 1998-09-03 Astra Ab Immediate release tablet
NZ511938A (en) * 1998-12-23 2004-02-27 Novartis Ag Use of AT-1 receptor antagonist or treating diseases associated with an increase of AT-1 receptor
US6465502B1 (en) * 1998-12-23 2002-10-15 Novartis Ag Additional therapeutic use
DE19913606A1 (de) * 1999-03-25 2000-09-28 Basf Ag Pulverförmige Solubilisationshilfsstoffe für feste pharmazeutische Darreichungsformen
EP1070741B1 (de) * 1999-07-19 2008-04-09 fit GmbH Coprozessiertes Polysaccharidprodukt mit vernetztem Polyvinylpyrrolidon
DE10005017A1 (de) * 2000-02-04 2001-08-09 Cognis Deutschland Gmbh Duftstofftabletten
JP4470343B2 (ja) * 2000-06-22 2010-06-02 ソニー株式会社 情報閲覧装置および情報出力制御方法
MXPA02012584A (es) * 2000-06-29 2004-05-17 Neuftec Ltd Aditivo de combustible.
US6761905B2 (en) * 2001-05-01 2004-07-13 Wei Ming Pharmaceutical Mfg. Co., Ltd. Process for the preparation of direct tabletting formulations and aids
US20040221631A1 (en) * 2002-09-05 2004-11-11 Kerrigan Kurt J. Composition for fertilizer tablet
WO2007013830A1 (en) 2005-07-26 2007-02-01 Portela & Ca. S.A. Nitrocatechol derivatives as comt inhibitors
EP1845097A1 (en) 2006-04-10 2007-10-17 Portela & Ca., S.A. Oxadiazole derivatives as COMT inhibitors
WO2008020990A1 (en) * 2006-08-09 2008-02-21 Mallinckrodt Baker, Inc. New direct compressible excipient blend
FI20080346A0 (fi) * 2008-05-09 2008-05-09 Atacama Labs Oy Prosessi lisäaineita sisältävän tabletin valmistamiseksi
DK2481410T3 (en) 2007-01-31 2016-10-24 Bial - Portela & Ca S A Nitrocatecholderivater as COMT inhibitors administered in a specific dosage regimen
US20100055180A1 (en) * 2007-10-10 2010-03-04 Mallinckrodt Baker, Inc. Directly Compressible Granular Microcrystalline Cellulose Based Excipient, Manufacturing Process and Use Thereof
WO2009048557A1 (en) * 2007-10-10 2009-04-16 Mallinckrodt Baker, Inc. Directly compressible high functionality granular microcrystalline cellulose based excipient, manufacturing process and use thereof
DE102008014237A1 (de) * 2008-03-14 2009-09-17 J. Rettenmaier & Söhne Gmbh + Co. Kg Direktverpressbares Tablettierhilfsmittel
BRPI0908731A2 (pt) 2008-03-17 2017-05-16 Bial - Portela & C A S A formas cristalinas de 5-[3-(2,5-dicloro-4,6-dimetil-1-óxi-piridina-3-il)[1,2,4]oxadiazol-5-il]-3-nitrobenzeno-1,2-diol
CN102215825A (zh) * 2008-11-19 2011-10-12 安万托特性材料股份有限公司 可直接压制的颗粒状的基于微晶纤维素的赋形剂、其制备方法及应用
US9144625B2 (en) * 2008-11-27 2015-09-29 Speciality Fibres And Materials Ltd. Cellulose ethylsulfonate-based absorbent material
US9221963B2 (en) * 2008-11-27 2015-12-29 Speciality Fibres And Materials Ltd. Absorbent material
TW201028168A (en) * 2008-12-19 2010-08-01 Solvay Pharm Bv Precompacted fast-disintegrating formulations of compounds with a low oral bioavailability
CN102448444B (zh) * 2009-04-01 2016-05-25 巴尔-波特拉及康邦亚股份有限公司 包括硝基儿茶酚衍生物的药物制剂及其制备方法
US20140045900A1 (en) 2011-02-11 2014-02-13 Bial-Portela & Ca, S.A. Administration regime for nitrocatechols
US9126988B2 (en) 2011-12-13 2015-09-08 Bial—Portela & Ca, S.A. Intermediate for preparing a catechol-O-methyltransferase inhibitor
CN104125831A (zh) * 2012-02-29 2014-10-29 老笃制药株式会社 固体组合物
CN102773942B (zh) * 2012-07-23 2015-07-01 北京中科日升科技有限公司 一种改性淀粉的处理方法
CN105324163B (zh) 2013-06-28 2017-10-31 陶氏环球技术有限责任公司 用于制造化合物的防积垢蒸馏塔和方法
WO2016083863A1 (en) 2014-11-28 2016-06-02 Bial - Portela & Ca, S.A. Medicaments for slowing parkinson's disease
CA2937365C (en) 2016-03-29 2018-09-18 F. Hoffmann-La Roche Ag Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2255263C3 (de) * 1972-11-11 1975-06-05 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von unlöslichen, vernetzten, nur wenig quellbaren Polymerisaten des N-Vinylpyrrolidon-(2)
DE3505433A1 (de) * 1985-02-16 1986-08-21 Basf Ag, 6700 Ludwigshafen Direkttablettierhilfsmittel
DE3506276C1 (de) * 1985-02-22 1986-04-24 Meggle Milchindustrie Gmbh & Co Kg, 8094 Reitmehring Direkttablettiermittel
ES2039226T3 (es) * 1986-12-30 1993-09-16 American Cyanamid Company Procedimiento para preparar composiciones que contienen policarbofil.

Also Published As

Publication number Publication date
US5840769A (en) 1998-11-24
CN1170610A (zh) 1998-01-21
CN1174775C (zh) 2004-11-10
DE19628617A1 (de) 1998-01-22
JPH1067651A (ja) 1998-03-10
EP0819429B1 (de) 2002-05-08
EP0819429A1 (de) 1998-01-21
DE59707194D1 (de) 2002-06-13

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