ES2177624T3 - Polimeros en cascada con restos aromaticos yodados. - Google Patents

Polimeros en cascada con restos aromaticos yodados.

Info

Publication number
ES2177624T3
ES2177624T3 ES95905095T ES95905095T ES2177624T3 ES 2177624 T3 ES2177624 T3 ES 2177624T3 ES 95905095 T ES95905095 T ES 95905095T ES 95905095 T ES95905095 T ES 95905095T ES 2177624 T3 ES2177624 T3 ES 2177624T3
Authority
ES
Spain
Prior art keywords
ioded
cascade
polymers
aromatic
remains
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95905095T
Other languages
English (en)
Inventor
Werner Krause
Franz-Karl Maier
Michael Bauer
Gabriele Schuhmann-Giampieri
Wolf-Rudiger Press
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of ES2177624T3 publication Critical patent/ES2177624T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0442—Polymeric X-ray contrast-enhancing agent comprising a halogenated group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/04—Preparatory processes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/0206—Polyalkylene(poly)amines
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/06—Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polyamides (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Graft Or Block Polymers (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

POLIMEROS DENDRIMERICOS QUE CONTIENEN IODO, DE FORMULA GENERAL (I) A-(X){SUB,B}, SIENDO A UN NUCLEO CON NITROGENO DE INDICE B, SIENDO B UN NUMERO DE 1 A 8, Y X ES UN RADICAL COMPUESTO DE (A) UNIDADES REPETITIVAS S Y RADICALES Z QUE DAN COMO MAXIMO 2{SUP,N} IMAGENES, N ES EL NUMERO DE GENERACIONES Y VALE DE 1 A 10, Y S Y Z TIENE DIFERENTES SIGNIFICADOS; SON COMPUESTOS PARA EL DIAGNOSTICO POR RAYOS X.
ES95905095T 1993-12-22 1994-12-21 Polimeros en cascada con restos aromaticos yodados. Expired - Lifetime ES2177624T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4344464A DE4344464A1 (de) 1993-12-22 1993-12-22 Kaskadenpolymere mit Iodaromaten

Publications (1)

Publication Number Publication Date
ES2177624T3 true ES2177624T3 (es) 2002-12-16

Family

ID=6506208

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95905095T Expired - Lifetime ES2177624T3 (es) 1993-12-22 1994-12-21 Polimeros en cascada con restos aromaticos yodados.

Country Status (24)

Country Link
US (1) US5593660A (es)
EP (1) EP0736056B1 (es)
JP (1) JP3696620B2 (es)
KR (1) KR100339447B1 (es)
CN (1) CN1075388C (es)
AT (1) ATE217330T1 (es)
AU (1) AU690189B2 (es)
CZ (1) CZ291539B6 (es)
DE (2) DE4344464A1 (es)
DK (1) DK0736056T5 (es)
ES (1) ES2177624T3 (es)
HU (1) HU221517B (es)
IL (1) IL112128A (es)
MY (1) MY112125A (es)
NO (1) NO312037B1 (es)
NZ (1) NZ278380A (es)
PL (1) PL177795B1 (es)
PT (1) PT736056E (es)
RU (1) RU2147592C1 (es)
SK (1) SK284111B6 (es)
TW (1) TW380143B (es)
UA (1) UA54370C2 (es)
WO (1) WO1995017448A2 (es)
ZA (1) ZA9410290B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4344460A1 (de) * 1993-12-22 1995-06-29 Schering Ag Metallkomplexe von dendrimeren Makromolekülen, diese enthaltende diagnostische Mittel sowie Verfahren zur Herstellung der Komplexe und Mittel
DE4425857A1 (de) * 1994-07-07 1996-01-11 Schering Ag Kaskaden-Polymer-Komplexe, Verfahren zur ihrer Herstellung und diese enthaltende pharmazeutische Mittel
US5756066A (en) * 1995-06-07 1998-05-26 Schering Aktiengesellschaft Iodine-containing peptides
DE19525924A1 (de) 1995-07-04 1997-01-09 Schering Ag Kaskaden-Polymer-Komplexe, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel
US6166200A (en) * 1995-07-04 2000-12-26 Schering Aktiengesellschaft Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes
US6225352B1 (en) 1996-08-14 2001-05-01 Warner-Lambert Company Low molecular weight dendritic compounds as pharmaceutical agents
DE10214217A1 (de) * 2002-03-22 2003-10-09 Schering Ag Kaskadenpolymere mit hydrophilen lodaromaten
RU2231295C1 (ru) * 2002-11-18 2004-06-27 Рутковский Евгений Александрович Способ непрямой магнитно-резонансной лимфографии
WO2005028432A1 (en) * 2003-09-12 2005-03-31 Dendritic Nanotechnologies, Inc. Hyperbranched (pamam) polymers via a one pot process
US7939611B2 (en) * 2004-07-08 2011-05-10 Reva Medical, Inc. Side-chain crystallizable polymers for medical applications
US8703113B2 (en) * 2004-07-08 2014-04-22 Reva Medical Inc. Side-chain crystallizable polymers for medical applications
IN2012DN02126A (es) * 2009-10-29 2015-08-21 Ge Healthcare As
BR112012033776A2 (pt) * 2010-07-12 2016-11-01 Ge Healthcare As composição,e, método de exame de raios-x.
EP3765096A1 (en) 2018-03-12 2021-01-20 Boston Scientific Scimed Inc. Scavenging methods, and scavenging system for radiocontrast agents
US12527871B2 (en) 2019-06-05 2026-01-20 Boston Scientific Scimed, Inc. Click chemistry capturable platinum-based antineoplastic agents
CN116425417A (zh) * 2023-04-17 2023-07-14 揭阳市栢轩顺陶瓷有限公司 一种防污抗菌的瓷制品釉料及其制备工艺

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364613A (en) * 1989-04-07 1994-11-15 Sieving Paul F Polychelants containing macrocyclic chelant moieties
DE3938992A1 (de) * 1989-11-21 1991-05-23 Schering Ag Kaskadenpolymer-gebundene komplexbildner, deren komplexe und konjugate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
AU3354993A (en) * 1991-12-04 1993-06-28 Guerbet S.A. Novel macromolecular polyamine iodine-containing compound, process for its preparation and its use as a contrast agent
DE4139962A1 (de) * 1991-12-04 1993-06-09 Basf Ag, 6700 Ludwigshafen, De Blockcopolymere aus acrylat- und methacrylateinheiten
JPH06506501A (ja) * 1992-01-13 1994-07-21 デーエスエム ナムローゼ フェンノートシャップ デンドライト高分子およびその製造
FR2703055B1 (fr) * 1993-03-22 1995-07-07 Guerbet Sa Nouveaux composés polyiodés, leur préparation et leur utilisation en tant que produits de contraste pour la radiologie .

Also Published As

Publication number Publication date
SK80396A3 (en) 1996-12-04
HU221517B (hu) 2002-11-28
EP0736056B1 (de) 2002-05-08
CZ165296A3 (en) 1996-10-16
JP3696620B2 (ja) 2005-09-21
AU690189B2 (en) 1998-04-23
HUT74388A (en) 1996-12-30
IL112128A0 (en) 1995-03-15
DE4344464A1 (de) 1995-06-29
DK0736056T5 (da) 2002-10-07
PL315145A1 (en) 1996-10-14
CN1137759A (zh) 1996-12-11
WO1995017448A2 (de) 1995-06-29
HU9601726D0 (en) 1996-08-28
NZ278380A (en) 1998-02-26
US5593660A (en) 1997-01-14
WO1995017448A3 (de) 1995-07-27
PT736056E (pt) 2002-10-31
NO962662L (no) 1996-08-22
KR100339447B1 (ko) 2002-10-31
CN1075388C (zh) 2001-11-28
SK284111B6 (sk) 2004-09-08
ATE217330T1 (de) 2002-05-15
JPH09506919A (ja) 1997-07-08
TW380143B (en) 2000-01-21
NO962662D0 (no) 1996-06-21
UA54370C2 (uk) 2003-03-17
AU1384595A (en) 1995-07-10
EP0736056A1 (de) 1996-10-09
ZA9410290B (en) 1995-09-04
DK0736056T3 (da) 2002-08-26
IL112128A (en) 1999-05-09
RU2147592C1 (ru) 2000-04-20
PL177795B1 (pl) 2000-01-31
CZ291539B6 (cs) 2003-03-12
MY112125A (en) 2001-04-30
NO312037B1 (no) 2002-03-04
DE59410117D1 (de) 2002-06-13

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