ES2179854T3 - Materiales aislados de felv prototipos para uso en modelos de enfermedades y vacunas. - Google Patents

Materiales aislados de felv prototipos para uso en modelos de enfermedades y vacunas.

Info

Publication number
ES2179854T3
ES2179854T3 ES95100871T ES95100871T ES2179854T3 ES 2179854 T3 ES2179854 T3 ES 2179854T3 ES 95100871 T ES95100871 T ES 95100871T ES 95100871 T ES95100871 T ES 95100871T ES 2179854 T3 ES2179854 T3 ES 2179854T3
Authority
ES
Spain
Prior art keywords
vaccines
diseases
felv
prototypes
models
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95100871T
Other languages
English (en)
Inventor
Edward A Hoover
James I Mullins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Harvard University
Colorado State University Research Foundation
Original Assignee
Harvard University
Colorado State University Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard University, Colorado State University Research Foundation filed Critical Harvard University
Application granted granted Critical
Publication of ES2179854T3 publication Critical patent/ES2179854T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13061—Methods of inactivation or attenuation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/819—Viral vaccine for feline species, e.g. cats

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

SE PRESENTAN CLONES MOLECULARES DE AISLADOS DEL VIRUS DE LA LEUCEMIA FELINA QUE CODIFICA (A) VIRUS PROTOTIPOS ALTAMENTE INFECCIOSOS, MINIMAMENTE PATOGENICOS, (B) UN GENOMA VARIANTE QUE ES DEFECTUOSO EN SU REPLICACION Y ESTA ASOCIADO CON INMUNODEFICIENCIAS FATALES EN GATOS O SIMILARES AL AIDS (FAIDS) O (C) UN GENOMA QUIMERICO QUE ES COMPETENTE PARA LA REPLICACION E INDUCE EL FAIDS. ESTOS CLONES MOLECULARES PUEDEN UTILIZARSE PARA GENERAR LINEAS CELULARES QUE PRODUCEN VIRUS INFECCIOSOS QUE SON UTILES EN LA PRODUCCION DE VACUNAS O EN LA GENERACION DE VIREMIAS O EN SISTEMAS DE DESAFIO A LAS ENFERMEDADES.
ES95100871T 1988-12-13 1989-12-12 Materiales aislados de felv prototipos para uso en modelos de enfermedades y vacunas. Expired - Lifetime ES2179854T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28413988A 1988-12-13 1988-12-13

Publications (1)

Publication Number Publication Date
ES2179854T3 true ES2179854T3 (es) 2003-02-01

Family

ID=23088994

Family Applications (2)

Application Number Title Priority Date Filing Date
ES95100871T Expired - Lifetime ES2179854T3 (es) 1988-12-13 1989-12-12 Materiales aislados de felv prototipos para uso en modelos de enfermedades y vacunas.
ES89122964T Expired - Lifetime ES2084596T3 (es) 1988-12-13 1989-12-12 Materiales aislados de felv prototipos para uso en modelos de enfermedades y vacunas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES89122964T Expired - Lifetime ES2084596T3 (es) 1988-12-13 1989-12-12 Materiales aislados de felv prototipos para uso en modelos de enfermedades y vacunas.

Country Status (12)

Country Link
US (1) US6042835A (es)
EP (2) EP0699758B1 (es)
JP (1) JP3164351B2 (es)
AT (2) ATE128730T1 (es)
AU (2) AU4616289A (es)
CA (1) CA2005311C (es)
DE (2) DE68924478T2 (es)
DK (1) DK172633B1 (es)
ES (2) ES2179854T3 (es)
GR (1) GR3018587T3 (es)
IE (1) IE74875B1 (es)
NZ (1) NZ231744A (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8901778D0 (en) * 1989-01-27 1989-03-15 Univ Court Of The University O Manipulatory technique
ZA93216B (en) * 1992-01-17 1993-08-18 Solvay Animal Health Inc Vaccine containing acemannan as an adjuvant.
GB9210337D0 (en) * 1992-05-14 1992-07-01 Univ Court Of The University O Feline leukaemia virus vaccine
DE69535669T2 (de) 1994-05-09 2008-12-04 Oxford Biomedica (Uk) Ltd. Retrovirale vektoren mit verminderter rekombinationsrate
US6013517A (en) * 1994-05-09 2000-01-11 Chiron Corporation Crossless retroviral vectors
JP4751326B2 (ja) 2003-09-04 2011-08-17 メダレックス インコーポレイテッド 発現ベクター
JP5060284B2 (ja) * 2004-03-30 2012-10-31 アンスティテュ・グスターブ・ルシ ウイルスタンパク質の免疫抑制作用のモデュレーションに関与するポリペプチド配列
US8895027B2 (en) 2011-07-20 2014-11-25 Merial Limited Recombinant feline leukemia virus vaccine containing optimized feline leukemia virus envelope gene
CN110382690B (zh) * 2017-02-16 2024-05-24 生物辐射实验室股份有限公司 新型逆转录酶及其用途

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4086134A (en) * 1973-09-18 1978-04-25 University Of Glasgow Method for preparation of vaccine against feline leukemia
GB1486186A (en) * 1973-09-18 1977-09-21 Univ Glasgow Vaccines against feline leukaemia and the group of diseases associated with feline leukaemis/virus infection
US4034081A (en) * 1973-09-18 1977-07-05 University Of Glasgow Vaccines against feline leukemia
US4406885A (en) * 1978-12-28 1983-09-27 Research Corporation Preparation of native oncornavirus envelope subunits and vaccines therefrom
US4264587A (en) * 1979-08-01 1981-04-28 Pedersen Niels C Vaccine for preventing persistent feline leukemia viremia in cats
US4434157A (en) * 1979-12-18 1984-02-28 The Ohio State University Research Foundation Method of recovering cell antigen and preparation of feline leukemia vaccine therefrom
US4332793A (en) * 1979-12-18 1982-06-01 The Ohio State University Research Foundation Method of recovering cell antigen and preparation of feline leukemia vaccine therefrom
US4405712A (en) * 1981-07-01 1983-09-20 The United States Of America As Represented By The Department Of Health And Human Services LTR-Vectors
US4593002A (en) * 1982-01-11 1986-06-03 Salk Institute Biotechnology/Industrial Associates, Inc. Viruses with recombinant surface proteins
US4701416A (en) * 1983-12-09 1987-10-20 Cetus Corporation Feline leukemia virus vaccine plasmids for fusion protein of the gp70 envelope protein of FELV
EP0156299A3 (en) * 1984-03-26 1987-04-01 Chiron Corporation Ltr modified viral vaccines
US4794168A (en) * 1984-04-24 1988-12-27 Scripps Clinic And Research Foundation Leukemia-associated virus immunogen, vaccine and assay
US4663436A (en) * 1984-04-24 1987-05-05 Scripps Clinic And Research Foundation Leukemia-associated virus immunogen, vaccine and assay
US4789702A (en) * 1984-05-18 1988-12-06 Cetus Corporation Feline leukemia virus vaccine
US4876089A (en) * 1984-09-06 1989-10-24 Chiron Corporation Feline leukemia virus protein vaccines
US4699785A (en) * 1984-09-18 1987-10-13 The Regents Of The University Of California Cell line producing feline leukemia virus
US4748234A (en) * 1985-06-26 1988-05-31 Cetus Corporation Process for recovering refractile bodies containing heterologous proteins from microbial hosts
AU607399B2 (en) * 1985-09-09 1991-03-07 Cetus Corporation Infectious recombinant virus vaccine for feline leukemia
US4734362A (en) * 1986-02-03 1988-03-29 Cambridge Bioscience Corporation Process for purifying recombinant proteins, and products thereof
JP2656521B2 (ja) * 1986-05-30 1997-09-24 ケンブリッジ・バイオサイエンス・コーポレーション ネコ白血病ウイルス抗原の製造法と用途
AU613316B2 (en) * 1986-09-12 1991-08-01 Genentech Inc. Improved recombinant expression
EP0262887A3 (en) * 1986-10-03 1989-07-26 Bayer Corporation Felv-infected feline cell line
US5306493A (en) * 1986-10-03 1994-04-26 Miles Inc. FeLV-infected feline cell line
JPH01501939A (ja) * 1987-01-28 1989-07-06 オーソ・フアーマシユーチカル・コーポレーシヨン 免疫抑制ペプチドおよび使用法
JP2796547B2 (ja) * 1987-09-11 1998-09-10 ジェネンテク，インコーポレイテッド 組換え細胞培養中でのポリペプチド発現の増大法

Also Published As

Publication number Publication date
ATE221119T1 (de) 2002-08-15
AU4616289A (en) 1990-06-21
NZ231744A (en) 1993-01-27
DK631089A (da) 1990-06-14
DK172633B1 (da) 1999-03-22
DE68924478D1 (de) 1995-11-09
CA2005311A1 (en) 1990-06-13
DE68924478T2 (de) 1996-03-07
EP0377842B1 (en) 1995-10-04
CA2005311C (en) 2006-05-30
DE68929419T2 (de) 2003-04-03
IE74875B1 (en) 1997-08-13
IE893974L (en) 1990-06-13
DE68929419D1 (de) 2002-08-29
US6042835A (en) 2000-03-28
GR3018587T3 (en) 1996-04-30
DK631089D0 (da) 1989-12-13
EP0699758A1 (en) 1996-03-06
ES2084596T3 (es) 1996-05-16
AU661134B2 (en) 1995-07-13
IE960745L (en) 1990-06-13
JPH03117490A (ja) 1991-05-20
EP0699758B1 (en) 2002-07-24
ATE128730T1 (de) 1995-10-15
EP0377842A1 (en) 1990-07-18
JP3164351B2 (ja) 2001-05-08
AU3710493A (en) 1993-07-15

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