ES2181690T3 - Procedimiento para estimular el crecimiento de los cabellos con derivados cationicos del minoxidil, recurriendo a una iontoforesis terapeutica. - Google Patents
Procedimiento para estimular el crecimiento de los cabellos con derivados cationicos del minoxidil, recurriendo a una iontoforesis terapeutica.Info
- Publication number
- ES2181690T3 ES2181690T3 ES93915191T ES93915191T ES2181690T3 ES 2181690 T3 ES2181690 T3 ES 2181690T3 ES 93915191 T ES93915191 T ES 93915191T ES 93915191 T ES93915191 T ES 93915191T ES 2181690 T3 ES2181690 T3 ES 2181690T3
- Authority
- ES
- Spain
- Prior art keywords
- minoxidil
- iontophoresis
- stimulate
- growth
- hair
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- ZFMITUMMTDLWHR-UHFFFAOYSA-N Minoxidil Chemical class NC1=[N+]([O-])C(N)=CC(N2CCCCC2)=N1 ZFMITUMMTDLWHR-UHFFFAOYSA-N 0.000 title abstract 4
- 230000001225 therapeutic effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 229960003632 minoxidil Drugs 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/50—Three nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
- A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/83—Electrophoresis; Electrodes; Electrolytic phenomena
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
EL INVENTO SE REFIERE A UN METODO PARA APLICAR DERIVADOS CATIONICOS DE MINOXIDIL QUE ES TRANSPORTADO POR UN MECANISMO DE IONTOFORESIS A FOLICULOS CAPILARES, DONDE LOS DERIVADOS CATIONICOS ESTIMULAN EL CRECIMIENTO CAPILAR. CADA UNO DE LOS DERIVADOS CATIONICOS DE MINOXIDIL SON SINTETIZADOS REACCIONANDO EL COMPUESTO ORIGEN DE MINOXIDIL CON UN ACIDO ORGANICO O INORGANICO PARA FORMAR EL DERIVADO CATIONICO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1539693A | 1993-02-09 | 1993-02-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2181690T3 true ES2181690T3 (es) | 2003-03-01 |
Family
ID=21771165
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES93915191T Expired - Lifetime ES2181690T3 (es) | 1993-02-09 | 1993-06-03 | Procedimiento para estimular el crecimiento de los cabellos con derivados cationicos del minoxidil, recurriendo a una iontoforesis terapeutica. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5466695A (es) |
| EP (1) | EP0683659B1 (es) |
| JP (1) | JPH08508717A (es) |
| KR (1) | KR100315329B1 (es) |
| AT (1) | ATE222484T1 (es) |
| AU (1) | AU690069B2 (es) |
| DE (1) | DE69332228T2 (es) |
| DK (1) | DK0683659T3 (es) |
| ES (1) | ES2181690T3 (es) |
| MX (1) | MX9401031A (es) |
| PT (1) | PT683659E (es) |
| WO (1) | WO1994017776A1 (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5679378A (en) * | 1995-12-18 | 1997-10-21 | Olim Industries Of Israel, North America, Ltd. | Method and material for hair therapy |
| US6094594A (en) * | 1996-08-14 | 2000-07-25 | Tapper; Robert | Hair removal system |
| GB9903216D0 (en) * | 1999-02-13 | 1999-04-07 | Zylepsis Ltd | Preservative compounds,compositions and methods of making and using the same |
| US6596266B2 (en) | 2000-02-18 | 2003-07-22 | Natural Science, Inc. | Compositions containing minoxidil and saw palmetto for treating baldness |
| US6866856B2 (en) * | 2002-12-31 | 2005-03-15 | Avon Products, Inc. | Compositions and delivery methods for the treatment of wrinkles, fine lines and hyperhidrosis |
| WO2005004984A1 (en) * | 2003-07-14 | 2005-01-20 | Power Paper Ltd. | Device and method for the treatment of pilosebaceous disorders |
| ES2931949T3 (es) * | 2005-03-29 | 2023-01-05 | Univ Pennsylvania | Minoxidilo para generar nuevos folículos pilosos y tratar la calvicie |
| EP2648676A4 (en) | 2010-12-06 | 2016-05-04 | Follica Inc | METHODS FOR TREATING CALVITIA AND PROMOTING HAIR GROWTH |
| FR3063227A1 (fr) | 2017-02-27 | 2018-08-31 | L'oreal | Procede de traitement cosmetique d'une matiere keratinique |
| IT201700055361A1 (it) * | 2017-05-22 | 2018-11-22 | Mdm Ind S R L | Metodo per la prevenzione e trattamento della caduta dei capelli. |
| CN113501791A (zh) * | 2021-07-20 | 2021-10-15 | 山东理工大学 | 一种用于治疗脱发的米诺地尔-水杨酸盐晶型及其制备方法 |
| CN118908900B (zh) * | 2024-10-10 | 2025-01-28 | 山东则正医药技术有限公司 | 一种米诺地尔乳酸盐晶型及其制备方法和应用 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3991755A (en) * | 1973-07-27 | 1976-11-16 | Medicon, Inc. | Iontophoresis apparatus for applying local anesthetics |
| US4139619A (en) * | 1976-05-24 | 1979-02-13 | The Upjohn Company | 6-Amino-4-(substituted amino)-1,2-dihydro-1-hydroxy-2-iminopyrimidine, topical compositions and process for hair growth |
| US4596812A (en) * | 1976-05-24 | 1986-06-24 | The Upjohn Company | Methods and solutions for treating male pattern alopecia |
| US4141359A (en) * | 1976-08-16 | 1979-02-27 | University Of Utah | Epidermal iontophoresis device |
| JPS5810066A (ja) * | 1981-07-10 | 1983-01-20 | 株式会社アドバンス | イオントフオレ−ゼ用プラスタ−構造体 |
| US4640689A (en) * | 1983-08-18 | 1987-02-03 | Drug Delivery Systems Inc. | Transdermal drug applicator and electrodes therefor |
| JPH0538753Y2 (es) * | 1984-10-20 | 1993-09-30 | ||
| US4722726A (en) * | 1986-02-12 | 1988-02-02 | Key Pharmaceuticals, Inc. | Method and apparatus for iontophoretic drug delivery |
| GB8606368D0 (en) * | 1986-03-14 | 1986-04-23 | Unilever Plc | Skin treatment composition |
| US4752285B1 (en) * | 1986-03-19 | 1995-08-22 | Univ Utah Res Found | Methods and apparatus for iontophoresis application of medicaments |
| LU86548A1 (fr) * | 1986-08-07 | 1988-03-02 | Oreal | Composition sous forme de gel pour induire et stimuler la croissance des cheveux et diminuer leur chute a base de derives de piperidino-pyrimidine |
| LU86574A1 (fr) * | 1986-09-08 | 1988-04-05 | Oreal | Composition pour induire et stimuler la croissance des cheveux et freiner leur chute,a base d'esters nicotiniques et de derives de pyrimidine |
| AU618517B2 (en) * | 1986-12-23 | 1992-01-02 | Eugene J. Van Scott | Additives enhancing topical actions of therapeutic agents |
| US4828837A (en) * | 1987-03-30 | 1989-05-09 | Liposome Technology, Inc. | Non-crystalline minoxidil composition, its production and application |
| US5030442A (en) * | 1987-03-30 | 1991-07-09 | Liposome Technology, Inc. | Non-crystalline minoxidil composition |
| LU86958A1 (fr) * | 1987-07-31 | 1989-03-08 | Oreal | Sels d'acide thiamorpholinone carboxylique et de derives de diamino-2,4 pyrimidine,leur utilisation en cosmetique et pharmacie |
| LU86959A1 (fr) * | 1987-07-31 | 1989-03-08 | Oreal | Nouveaux derives d'ureylene triamino-2,4,6 pyrimidine oxyde-3,leur preparation et leur utilisation en cosmetique et dermopharmacie |
| US4997418A (en) * | 1988-04-21 | 1991-03-05 | C. P. Chambers | Epidermal iontophoresis device |
| US5195953A (en) * | 1988-04-21 | 1993-03-23 | Demartini Richard J | Method of increasing skin absorption of a drug |
| LU87249A1 (fr) * | 1988-06-17 | 1990-02-28 | Oreal | Composition pour induire et stimuler la croissance des cheveux et/ou freiner leur chute,a base d'un agent tensio-actif amphotere et d'un derive de pyrimidine |
| US4979938A (en) * | 1989-05-11 | 1990-12-25 | Iomed, Inc. | Method of iontophoretically treating acne, furuncles and like skin disorders |
-
1993
- 1993-06-03 ES ES93915191T patent/ES2181690T3/es not_active Expired - Lifetime
- 1993-06-03 PT PT93915191T patent/PT683659E/pt unknown
- 1993-06-03 WO PCT/US1993/005256 patent/WO1994017776A1/en not_active Ceased
- 1993-06-03 AU AU45269/93A patent/AU690069B2/en not_active Ceased
- 1993-06-03 KR KR1019950703271A patent/KR100315329B1/ko not_active Expired - Fee Related
- 1993-06-03 JP JP6517991A patent/JPH08508717A/ja active Pending
- 1993-06-03 DK DK93915191T patent/DK0683659T3/da active
- 1993-06-03 DE DE69332228T patent/DE69332228T2/de not_active Expired - Fee Related
- 1993-06-03 AT AT93915191T patent/ATE222484T1/de not_active IP Right Cessation
- 1993-06-03 EP EP93915191A patent/EP0683659B1/en not_active Expired - Lifetime
-
1994
- 1994-02-09 MX MX9401031A patent/MX9401031A/es not_active IP Right Cessation
- 1994-07-11 US US08/272,880 patent/US5466695A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH08508717A (ja) | 1996-09-17 |
| EP0683659A1 (en) | 1995-11-29 |
| KR100315329B1 (ko) | 2002-04-24 |
| EP0683659B1 (en) | 2002-08-21 |
| WO1994017776A1 (en) | 1994-08-18 |
| DK0683659T3 (da) | 2002-12-16 |
| ATE222484T1 (de) | 2002-09-15 |
| MX9401031A (es) | 1994-08-31 |
| AU4526993A (en) | 1994-08-29 |
| KR960700680A (ko) | 1996-02-24 |
| AU690069B2 (en) | 1998-04-23 |
| DE69332228D1 (de) | 2002-09-26 |
| PT683659E (pt) | 2003-01-31 |
| US5466695A (en) | 1995-11-14 |
| DE69332228T2 (de) | 2003-04-17 |
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