ES2189821T3 - Procedimientos de cultivo, de atenuacion de la virulencia y de la clonacion in vitro de parasitos del genero babesia y sus aplicaciones. - Google Patents

Procedimientos de cultivo, de atenuacion de la virulencia y de la clonacion in vitro de parasitos del genero babesia y sus aplicaciones.

Info

Publication number
ES2189821T3
ES2189821T3 ES95402004T ES95402004T ES2189821T3 ES 2189821 T3 ES2189821 T3 ES 2189821T3 ES 95402004 T ES95402004 T ES 95402004T ES 95402004 T ES95402004 T ES 95402004T ES 2189821 T3 ES2189821 T3 ES 2189821T3
Authority
ES
Spain
Prior art keywords
parasites
vitro
culture
virulence
babesia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95402004T
Other languages
English (en)
Inventor
Philippe Mahl
Marie-Helene Dick-Madelpuech
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Virbac SA
Original Assignee
Virbac SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Virbac SA filed Critical Virbac SA
Application granted granted Critical
Publication of ES2189821T3 publication Critical patent/ES2189821T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/002—Protozoa antigens
    • A61K39/015—Hemosporidia antigens, e.g. Plasmodium antigens
    • A61K39/018—Babesia antigens, e.g. Theileria antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/10—Protozoa; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/36—Adaptation or attenuation of cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6893—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for protozoa

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

LA INVENCION SE ACERCA A PROCESOS DE CULTIVO, DE ATENUACION DE LA VIRULENCIA Y DE LA CLONACION IN VITRO DE PARASITOS DEL TIPO BABESIA, A PARASITOS DE VIRULENCIA ATENUADA Y A CLONES DEL TIPO BABESIA, A SONDA NUCLEOTIDICAS OBTENIDAS DEL ADN DE DICHOS CLONES, A VACUNAS VIVAS ATENUADAS CONTRA LAS BABEOVIOSIS Y A LAS APLICACIONES DE DICHOS PROCESOS. EL PROCESO DE CULTIVO IN VITRO COMPRENDE AL MENOS UNA INCUBACION DE HEMATIES PARASITADOS POR DICHOS PARASITOS EN PRESENCIA DE HEMATIES HOMOLOGOS NO PARASITADOS EN UN MEDIO Y CONDICIONES DE CULTIVO APROPIADOS Y SE CARACTERIZA EN QUE LA O LAS INCUBACIONES SE REALIZAN EN PRESENCIA DE CELULAS DESTINADAS A SERVIR DE SOPORTE AL CULTIVO DE DICHOS PARASITOS. EL PROCESOS DE ATENUACION IN VITRO DE LA VIRULENCIA DE LOS PARASITOS COMPRENDE EL CULTIVO DE DICHOS PARASITOS DURANTE AL MENOS OCHO DIAS MIENTRAS QUE EL PROCESO DE CLONACION IN VITRO COMPRENDE EL AISLAMIENTO DE UN SOLO PARASITO Y EL CULTIVO DE ESTE ULTIMO, PUDIENDO REPETIRSE ESTAS OPERACIONES.
ES95402004T 1994-09-08 1995-09-05 Procedimientos de cultivo, de atenuacion de la virulencia y de la clonacion in vitro de parasitos del genero babesia y sus aplicaciones. Expired - Lifetime ES2189821T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9410762A FR2724392B1 (fr) 1994-09-08 1994-09-08 Procedes de culture, d'attenuation de la virulence et de clonage in vitro de parasites du genre babesia et leurs applications

Publications (1)

Publication Number Publication Date
ES2189821T3 true ES2189821T3 (es) 2003-07-16

Family

ID=9466789

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95402004T Expired - Lifetime ES2189821T3 (es) 1994-09-08 1995-09-05 Procedimientos de cultivo, de atenuacion de la virulencia y de la clonacion in vitro de parasitos del genero babesia y sus aplicaciones.

Country Status (6)

Country Link
US (1) US5824537A (es)
EP (1) EP0700992B1 (es)
AU (1) AU3045495A (es)
DE (1) DE69529373T2 (es)
ES (1) ES2189821T3 (es)
FR (1) FR2724392B1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT502702B1 (de) * 2005-05-12 2008-05-15 Veterinaermedizinische Uni Wie Verfahren zur herstellung und anwendung von protozoenkulturen
WO2007070809A2 (en) * 2005-12-12 2007-06-21 Mcgill University Biomarkers for babesia
WO2018053432A1 (en) 2016-09-19 2018-03-22 Fuller Laboratories In vitro propagation of babesia microti

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4596707A (en) * 1979-04-30 1986-06-24 University Of Illinois Foundation Babesia parasite antigen useful in vaccine and diagnostic reagent
GB2062463B (en) * 1979-11-06 1983-11-23 Commw Scient Ind Res Org Babesiosis vaccine
AU558071B2 (en) * 1982-11-03 1987-01-15 Curators Of The University Of Missouri, The Live vaccine for bovine babesiosis and method of preparation
US4590072A (en) * 1982-11-03 1986-05-20 Curators Of The University Of Missouri Live vaccine for bovine babesiosis and method of preparation
FR2589063B1 (fr) * 1985-10-24 1988-08-26 Rhone Merieux Procede de culture de babesia canis, application a la preparation d'antigenes et de vaccins, et antigenes et vaccins contre la piroplasmose
GB8630851D0 (en) * 1986-12-24 1987-02-04 Department Of Agriculture For Babesia divergens antigen & vaccine
US5273884A (en) * 1989-01-25 1993-12-28 Commonwealth Scientific & Industrial Polypetides, antigens or vaccines protective against babesiosis
FR2655853B1 (fr) * 1989-12-20 1994-06-10 Centre Nat Rech Scient Procede de culture intensive, in vitro, de souches de babesia divergens, procede de preparation d'exoantigenes et vaccin contenant ces antigenes.
ZA93236B (en) * 1992-01-15 1993-08-16 Commw Scient Ind Res Org Babesial rhoptry antigens.

Also Published As

Publication number Publication date
FR2724392A1 (fr) 1996-03-15
FR2724392B1 (fr) 1996-12-13
AU3045495A (en) 1996-03-21
US5824537A (en) 1998-10-20
EP0700992A1 (fr) 1996-03-13
DE69529373D1 (de) 2003-02-20
DE69529373T2 (de) 2003-11-20
EP0700992B1 (fr) 2003-01-15

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