ES2190175T3 - Formulacion de gel hidrofobico con base de acetato de vitamina e de aplicacion topica. - Google Patents
Formulacion de gel hidrofobico con base de acetato de vitamina e de aplicacion topica.Info
- Publication number
- ES2190175T3 ES2190175T3 ES99203138T ES99203138T ES2190175T3 ES 2190175 T3 ES2190175 T3 ES 2190175T3 ES 99203138 T ES99203138 T ES 99203138T ES 99203138 T ES99203138 T ES 99203138T ES 2190175 T3 ES2190175 T3 ES 2190175T3
- Authority
- ES
- Spain
- Prior art keywords
- formulation
- base
- hydrophobic gel
- topical application
- cyclomethicone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 238000009472 formulation Methods 0.000 title abstract 3
- 230000002209 hydrophobic effect Effects 0.000 title abstract 2
- 230000000699 topical effect Effects 0.000 title abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 title 1
- 229940088594 vitamin Drugs 0.000 title 1
- 229930003231 vitamin Natural products 0.000 title 1
- 235000013343 vitamin Nutrition 0.000 title 1
- 239000011782 vitamin Substances 0.000 title 1
- 150000003722 vitamin derivatives Chemical class 0.000 title 1
- XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 abstract 3
- 229940086555 cyclomethicone Drugs 0.000 abstract 3
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 abstract 1
- 239000004359 castor oil Substances 0.000 abstract 1
- 235000019438 castor oil Nutrition 0.000 abstract 1
- ZAKOWWREFLAJOT-UHFFFAOYSA-N d-alpha-Tocopheryl acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-UHFFFAOYSA-N 0.000 abstract 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 abstract 1
- UQEAIHBTYFGYIE-UHFFFAOYSA-N hexamethyldisiloxane Chemical compound C[Si](C)(C)O[Si](C)(C)C UQEAIHBTYFGYIE-UHFFFAOYSA-N 0.000 abstract 1
- 229920001296 polysiloxane Polymers 0.000 abstract 1
- 229940042585 tocopherol acetate Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
- A61K8/585—Organosilicon compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Abstract
Una formulación para utilización tópica en forma de gel hidrófobo que comprende, en porcentajes en peso sobre el peso total de la formulación:- entre 20 y 70% de acetato de vitamina E,- entre 20 y 70% de una silicona volátil elegida en el grupo que ciclometicona de pentámero, ciclometicona de tetrámero ciclometicona de hexámero, hexametildisiloxano y sus mezclas.- Entre 7 y 13% de aceite de castor hidrogenado.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1998MI002075A IT1302275B1 (it) | 1998-09-25 | 1998-09-25 | Formulazione di gel idrofobo a base di vitamina e acetato perapplicazione topica. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2190175T3 true ES2190175T3 (es) | 2003-07-16 |
Family
ID=11380764
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES99203138T Expired - Lifetime ES2190175T3 (es) | 1998-09-25 | 1999-09-24 | Formulacion de gel hidrofobico con base de acetato de vitamina e de aplicacion topica. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6280752B1 (es) |
| EP (1) | EP0998943B1 (es) |
| AT (1) | ATE232742T1 (es) |
| DE (1) | DE69905438T2 (es) |
| ES (1) | ES2190175T3 (es) |
| IT (1) | IT1302275B1 (es) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6479060B1 (en) * | 2001-09-04 | 2002-11-12 | Healthpoint, Ltd. | Elegant hydrogenated castor oil ointments |
| US6979438B2 (en) | 2002-01-25 | 2005-12-27 | The Procter & Gamble Company | Antiperspirant compositions containing petrolatum |
| FR2871695B1 (fr) * | 2004-06-17 | 2008-07-04 | Galderma Sa | Composition pharmaceutique comprenant un agent silicone et deux principes actifs solubilises |
| FR2871698B1 (fr) * | 2004-06-17 | 2008-07-04 | Galderma Sa | Composition sous forme de spray comprenant une association d'actifs pharmaceutiques et une phase huileuse |
| MXPA06014397A (es) * | 2004-06-17 | 2007-02-15 | Galderma Sa | Composicion en forma de aerosol que comprende una combinacion de un corticoide y un derivado de la vitamina d en una fase aceitosa. |
| JP2008502647A (ja) * | 2004-06-17 | 2008-01-31 | ガルデルマ・ソシエテ・アノニム | シリコーン剤、コルチコステロイドおよびビタミンdまたはその誘導体を含む乾癬治療用組成物 |
| FR2871697B1 (fr) | 2004-06-17 | 2007-06-29 | Galderma Sa | Composition sous forme de spray comprenant une association d'actifs pharmaceutiques, une phase alcoolique, au moins un silicone volatile et une phase huileuse non volatile |
| GB0506139D0 (en) * | 2005-03-24 | 2005-05-04 | Transphase Ltd | A transdermal topical composition and its uses |
| US20080299182A1 (en) * | 2007-03-01 | 2008-12-04 | Shuyuan Zhang | Methods and formulations for topical gene therapy |
| HUP0900072A2 (hu) | 2009-02-06 | 2010-09-28 | Egis Gyogyszergyar Nyilvanosan | Transzdermális gyógyszerkészítmények |
| IT1393056B1 (it) * | 2008-09-22 | 2012-04-11 | Bio Lo Ga Srl | Uso di vitamina e o suoi derivati per il controllo di artropodi |
| ES2335729B1 (es) * | 2008-09-30 | 2011-02-09 | Laboratorios Salvat, S.A. | Composicion cosmetica para pieles sensibles. |
| ITMI20090480A1 (it) * | 2009-03-27 | 2010-09-28 | Bio Lo Ga Srl | Supporto tessile imbevuto di una composizione detergente/idratante |
| US11279674B2 (en) | 2011-01-03 | 2022-03-22 | The William M. Yarbrough Foundation | Isothiocyanate functional surfactant and associated method of use |
| US8933119B2 (en) | 2011-01-03 | 2015-01-13 | The William M. Yarbrough Foundation | Method for treating phytophotodermatitis |
| US9962361B2 (en) | 2011-01-03 | 2018-05-08 | The William M. Yarbrough Foundation | Isothiocyanate functional surfactants, formulations incorporating the same, and associated methods of use |
| US11407713B2 (en) | 2011-01-03 | 2022-08-09 | The William M. Yarbrough Foundation | Isothiocyanate functional surfactants, formulations incorporating the same, and associated methods of use |
| US10647668B2 (en) | 2011-01-03 | 2020-05-12 | The William M. Yarbrough Foundation | Isothiocyanate functional surfactant and associated method of use |
| US10640464B2 (en) | 2011-01-03 | 2020-05-05 | The William M. Yarbrough Foundation | Use of isothiocyanate functional surfactants as Nrf2 inducers to treat epidermolysis bullosa simplex and related diseases |
| US10273205B2 (en) | 2011-01-03 | 2019-04-30 | The William M. Yarbrough Foundation | Isothiocyanate functional surfactants, formulations incorporating isothiocyanate functional surfactants and associated methods for treating biofilms |
| US10308599B2 (en) | 2011-01-03 | 2019-06-04 | The William M. Yarbrough Foundation | Isothiocyanate functional surfactants, formulations incorporating the same, and associated methods of use |
| US8865765B2 (en) | 2011-01-12 | 2014-10-21 | The William M. Yarbrough Foundation | Method for treating eczema |
| US9532969B2 (en) | 2011-02-08 | 2017-01-03 | The William M. Yarbrough Foundation | Method for treating psoriasis |
| US10441561B2 (en) | 2012-07-26 | 2019-10-15 | The William M. Yanbrough Foundation | Method for treating benign prostatic hyperplasia (BPH), prostatitis, and prostate cancer |
| US10434081B2 (en) | 2012-07-26 | 2019-10-08 | The William M. Yarbrough Foundation | Inhibitors of macrophage migration inhibitory factor |
| US9839621B2 (en) | 2012-07-26 | 2017-12-12 | The William M. Yarbrough Foundation | Method for treating bladder cancer |
| US10434082B2 (en) | 2012-07-26 | 2019-10-08 | The William M. Yarbrough Foundation | Isothiocyanate functional compounds augmented with secondary antineoplastic medicaments and associated methods for treating neoplasms |
| US9949943B2 (en) | 2012-07-26 | 2018-04-24 | The William M. Yarbrough Foundation | Method for treating neurodegenerative diseases |
| US8865772B2 (en) | 2012-07-26 | 2014-10-21 | The William M. Yarbrough Foundation | Method for treating skin cancer |
| US10335387B2 (en) | 2012-07-26 | 2019-07-02 | The William M. Yarbrough Foundation | Method for treating infectious diseases with isothiocyanate functional compounds |
| US10080734B2 (en) | 2012-07-26 | 2018-09-25 | The William M. Yarbrough Foundation | Method for treating autism and other neurodevelopmental disorders |
| SMT201900670T1 (it) | 2015-02-26 | 2020-01-14 | Bio Lo Ga Srl | Composizione contenente vitamina e acetato per uso nel trattamento topico di croste e infiammazione risultanti da trapianto di capelli |
| ITUB20153889A1 (it) | 2015-09-25 | 2017-03-25 | Bio Lo Ga Srl | Gel idrofobico a base di vitamina E esente da prodotti siliconici per applicazione topica |
| IT201700024605A1 (it) * | 2017-03-06 | 2018-09-06 | Bio Lo Ga Srl | Gel idrofobico a base di vitamina E esente da prodotti siliconici per applicazione topica |
| IT201700058311A1 (it) | 2017-05-29 | 2018-11-29 | Bio Lo Ga Srl | Formulazione a base di vitamina E o di un suo estere per il trattamento di biofilm batterici e fungini |
| CN107669501A (zh) * | 2017-11-15 | 2018-02-09 | 陈荷芬 | 一种防裂型植物滋养护手霜 |
| CN110668944B (zh) * | 2019-04-19 | 2022-08-16 | 江西阿尔法高科药业有限公司 | 一种油酸乙酯的精制方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4410517A (en) * | 1980-05-20 | 1983-10-18 | Theodore Stillman | Vitamin E (tocopherol) compositions which resemble petrolatum |
| US4551332A (en) * | 1981-08-05 | 1985-11-05 | Theodore Stillman | Vitamin E compositions and methods |
| IT1284506B1 (it) * | 1996-09-11 | 1998-05-21 | Giorgio Panin | Formulazioni per uso topico |
| US6013270A (en) * | 1998-04-20 | 2000-01-11 | The Procter & Gamble Company | Skin care kit |
| US6146664A (en) * | 1998-07-10 | 2000-11-14 | Shaklee Corporation | Stable topical ascorbic acid compositions |
-
1998
- 1998-09-25 IT IT1998MI002075A patent/IT1302275B1/it active IP Right Grant
-
1999
- 1999-09-24 AT AT99203138T patent/ATE232742T1/de not_active IP Right Cessation
- 1999-09-24 EP EP99203138A patent/EP0998943B1/en not_active Expired - Lifetime
- 1999-09-24 ES ES99203138T patent/ES2190175T3/es not_active Expired - Lifetime
- 1999-09-24 DE DE69905438T patent/DE69905438T2/de not_active Expired - Lifetime
- 1999-09-27 US US09/405,224 patent/US6280752B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0998943A1 (en) | 2000-05-10 |
| EP0998943B1 (en) | 2003-02-19 |
| ATE232742T1 (de) | 2003-03-15 |
| US6280752B1 (en) | 2001-08-28 |
| DE69905438T2 (de) | 2003-11-20 |
| DE69905438D1 (de) | 2003-03-27 |
| ITMI982075A1 (it) | 2000-03-25 |
| IT1302275B1 (it) | 2000-09-05 |
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