ES2190663T3 - Formulacion de un adhesivo de fibrina para tejidos y procedimiento para su fabricacion. - Google Patents

Formulacion de un adhesivo de fibrina para tejidos y procedimiento para su fabricacion.

Info

Publication number
ES2190663T3
ES2190663T3 ES99950784T ES99950784T ES2190663T3 ES 2190663 T3 ES2190663 T3 ES 2190663T3 ES 99950784 T ES99950784 T ES 99950784T ES 99950784 T ES99950784 T ES 99950784T ES 2190663 T3 ES2190663 T3 ES 2190663T3
Authority
ES
Spain
Prior art keywords
manufacture
formulation
fibrin tissue
granules
adhesive fibrin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99950784T
Other languages
English (en)
Other versions
ES2190663T5 (es
Inventor
Armin Prasch
Bernhard Luy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glatt Process Technology GmbH
Original Assignee
Glatt Process Technology GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7885853&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2190663(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glatt Process Technology GmbH filed Critical Glatt Process Technology GmbH
Application granted granted Critical
Publication of ES2190663T3 publication Critical patent/ES2190663T3/es
Publication of ES2190663T5 publication Critical patent/ES2190663T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/106—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/043—Mixtures of macromolecular materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

Formulación de un adhesivo de fibrina para tejidos que contiene trombina, fibrinógeno y factor XIII, caracterizada porque la trombina y el fibrinógeno con el factor XIII están como mezcla en forma de granulado con capacidad de fluencia y sólido, habiéndose obtenido el granulado por secado de las soluciones o suspensiones de proteínas en un aparato de lecho fluidizado y porque el granulado presenta un tamaño de partículas de 40-1000 micram.
ES99950784T 1998-10-27 1999-10-27 Formulacion de un adhesivo de fibrina para tejidos y procedimiento para su fabricacion. Expired - Lifetime ES2190663T5 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19849589A DE19849589C1 (de) 1998-10-27 1998-10-27 Fibrin-Gewebekleber-Formulierung und Verfahren zu dessen Herstellung
DE19849589 1998-10-27

Publications (2)

Publication Number Publication Date
ES2190663T3 true ES2190663T3 (es) 2003-08-01
ES2190663T5 ES2190663T5 (es) 2009-06-15

Family

ID=7885853

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99950784T Expired - Lifetime ES2190663T5 (es) 1998-10-27 1999-10-27 Formulacion de un adhesivo de fibrina para tejidos y procedimiento para su fabricacion.

Country Status (11)

Country Link
US (1) US6596318B2 (es)
EP (1) EP1124589B2 (es)
JP (1) JP2002528180A (es)
AT (1) ATE230618T1 (es)
AU (1) AU765770B2 (es)
CA (1) CA2349000C (es)
DE (2) DE19849589C1 (es)
DK (1) DK1124589T3 (es)
ES (1) ES2190663T5 (es)
RU (1) RU2242996C2 (es)
WO (1) WO2000024436A1 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7572769B2 (en) * 1998-12-23 2009-08-11 Csl Behring Gmbh Fibrin adhesive granulate and method for its preparation
AU754458B2 (en) † 1998-12-23 2002-11-14 Csl Behring Gmbh Fibrin-based glue granulate and corresponding production method
DE19962221A1 (de) * 1999-10-01 2001-05-23 Glatt Process Technology Gmbh Dispersionen für Depotapplikationen
US6468660B2 (en) 2000-12-29 2002-10-22 St. Jude Medical, Inc. Biocompatible adhesives
AU2002249958B2 (en) 2001-01-16 2007-11-08 Vascular Therapies, Inc. Implantable device containing resorbable matrix material and anti-proliferative drugs for preventing or treating failure of hemodialysis vascular access and other vascular grafts
AUPR272901A0 (en) * 2001-01-25 2001-02-22 Gainful Plan Limited Method of preparing biological materials and preparations produced using same
AU2005317689B2 (en) 2004-12-20 2011-05-12 Amo Groningen B.V. Amphiphilic block copolymers and their use
GB0623607D0 (en) * 2006-11-27 2007-01-03 Haemostatix Ltd Tissue adhesive
WO2008106646A2 (en) * 2007-03-01 2008-09-04 Introgen Therapeutics, Inc Methods and formulations for topical gene therapy
GB0909136D0 (en) * 2009-05-28 2009-07-01 Profibrix Bv Dry powder composition
GB0909131D0 (en) * 2009-05-28 2009-07-01 Quadrant Drug Delivery Ltd Dry powder fibrin sealant
GB0909129D0 (en) * 2009-05-28 2009-07-01 Quadrant Drug Delivery Ltd Dry powder fibrin sealant
US9119897B2 (en) 2009-05-28 2015-09-01 Profibrix B.V. Dry powder fibrin sealant
BR112012016633A2 (pt) * 2010-01-08 2016-04-19 Profibrix Bv composição farmacêutica em pó seco e método de tratamento de ferida.
KR101786786B1 (ko) 2010-01-28 2017-10-18 옴릭스 바이오파머슈티컬스 리미티드 개선된 피브린 밀봉 방법
US9468679B2 (en) 2011-03-28 2016-10-18 Ablynx N.V. Method for producing solid formulations comprising immunoglobulin single variable domains
CN105188740A (zh) * 2013-03-07 2015-12-23 普罗菲布里克有限公司 包含凝血酶和纤维蛋白原的粉末制剂
DE102013203988A1 (de) * 2013-03-08 2014-09-11 Aesculap Ag Gewebefusionsmittel
DE102013203997A1 (de) * 2013-03-08 2014-09-11 Aesculap Ag Medizinisches Produkt
DE102013203999A1 (de) 2013-03-08 2014-09-11 Aesculap Ag Gewebefusionsmittel
NZ741447A (en) 2015-11-06 2022-12-23 Ethicon Inc Compacted hemostatic cellulosic aggregates
EP4374861A3 (en) 2015-11-16 2024-08-07 MedinCell S.A. A method for morselizing and/or targeting pharmaceutically active principles to synovial tissue
US11413335B2 (en) 2018-02-13 2022-08-16 Guangzhou Bioseal Biotech Co. Ltd Hemostatic compositions and methods of making thereof
CN107754005B (zh) 2016-08-15 2021-06-15 广州倍绣生物技术有限公司 止血组合物及其制造方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU741878A1 (ru) * 1978-01-31 1980-06-25 Киевский Научно-Исследовательский Институт Гематологии И Переливания Крови Способ получени гемостатической губки
RU2067447C1 (ru) * 1992-03-30 1996-10-10 Научно-производственное объединение "Танаис" Способ получения гемостатического средства "желпластан"
DE4441167C1 (de) 1994-11-18 1996-03-14 Fraunhofer Ges Forschung Verfahren zur Trocknung von Blutplasma
US5658588A (en) * 1995-03-31 1997-08-19 University Of Cincinnati Fibrinogen-coated liposomes
WO1997044015A1 (en) * 1996-05-17 1997-11-27 Andaris Limited Microparticles and their use in wound therapy
US6150505A (en) * 1997-09-19 2000-11-21 Hadasit Medical Research Services & Development Ltd. Fibrin microbeads prepared from fibrinogen, thrombin and factor XIII
AU754458B2 (en) † 1998-12-23 2002-11-14 Csl Behring Gmbh Fibrin-based glue granulate and corresponding production method

Also Published As

Publication number Publication date
US6596318B2 (en) 2003-07-22
JP2002528180A (ja) 2002-09-03
DE19849589C1 (de) 2000-06-15
RU2242996C2 (ru) 2004-12-27
WO2000024436A8 (de) 2000-09-21
EP1124589B1 (de) 2003-01-08
EP1124589A1 (de) 2001-08-22
DE59903994D1 (de) 2003-02-13
ES2190663T5 (es) 2009-06-15
CA2349000A1 (en) 2000-05-04
DK1124589T3 (da) 2003-05-05
AU6342899A (en) 2000-05-15
WO2000024436A1 (de) 2000-05-04
AU765770B2 (en) 2003-09-25
US20020037323A1 (en) 2002-03-28
EP1124589B2 (de) 2009-02-25
ATE230618T1 (de) 2003-01-15
CA2349000C (en) 2009-08-04

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