ES2191446T3 - Compuestos ciclicos de 5 miembros. - Google Patents
Compuestos ciclicos de 5 miembros.Info
- Publication number
- ES2191446T3 ES2191446T3 ES99937011T ES99937011T ES2191446T3 ES 2191446 T3 ES2191446 T3 ES 2191446T3 ES 99937011 T ES99937011 T ES 99937011T ES 99937011 T ES99937011 T ES 99937011T ES 2191446 T3 ES2191446 T3 ES 2191446T3
- Authority
- ES
- Spain
- Prior art keywords
- ring
- membered ring
- compounds
- members
- same
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 125000002433 cyclopentenyl group Chemical group C1(=CCCC1)* 0.000 abstract 2
- 125000001511 cyclopentyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 abstract 2
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 230000003327 cancerostatic effect Effects 0.000 abstract 1
- 230000001766 physiological effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
- C07C321/22—Thiols, sulfides, hydropolysulfides, or polysulfides having thio groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Adornments (AREA)
- Food-Manufacturing Devices (AREA)
Abstract
Un compuesto cíclico de cinco miembros de fórmula [I]: **(Fórmula)** en la que el enlace en el anillo de cinco miembros representado por una línea discontinua quiere decir que el anillo de cinco miembros puede ser un anillo de ciclopenteno que tiene un doble enlace o un anillo de ciclopentano saturado; si el anillo de cinco miembros es un anillo de ciclopenteno, X es OR1, Y es = O y Z es H; si el anillo de cinco miembros es un anillo de ciclopentano, X es =O, Y es OR2 y Z es OR3; R1 es R4 o -(CO)-R5; R2 es H, R6 o -(CO)-R7; y R3 es H, R8 o (CO)-R9 (en los que R4, R5, R6, R7, R8 y R9 pueden ser idénticos o diferentes unos de otros, y son un grupo alifático, un grupo aromático o un grupo alifático-aromático, y R5, R7 y R9 pueden ser H), con tal de que R2 y R3 no sean simultáneamente H; y W es un resto en el que se retira un grupo SH de un compuesto que contiene un grupo SH, o uno de sus isómeros ópticos, o una de sus sales.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP23274698 | 1998-08-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2191446T3 true ES2191446T3 (es) | 2003-09-01 |
Family
ID=16944120
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES99937011T Expired - Lifetime ES2191446T3 (es) | 1998-08-19 | 1999-08-10 | Compuestos ciclicos de 5 miembros. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6380262B1 (es) |
| EP (1) | EP1106624B1 (es) |
| KR (1) | KR20010072317A (es) |
| CN (1) | CN1225472C (es) |
| AT (1) | ATE236927T1 (es) |
| AU (1) | AU5195899A (es) |
| DE (1) | DE69906759T2 (es) |
| ES (1) | ES2191446T3 (es) |
| TW (1) | TWI238828B (es) |
| WO (1) | WO2000011021A1 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7326542B2 (en) | 1998-12-02 | 2008-02-05 | Princeton University | Compositions and methods for regulating bacterial pathogenesis |
| US6720415B2 (en) | 1998-12-02 | 2004-04-13 | Princeton University | Compositions and methods for regulating bacterial pathogenesis |
| EP1170007A4 (en) * | 1999-02-19 | 2004-12-15 | Takara Bio Inc | DRUGS |
| JP2003532698A (ja) | 2000-05-10 | 2003-11-05 | プリンストン ユニバーシティ | 細菌の増殖および病理発生を調節するための化合物ならびに方法 |
| US20030032625A1 (en) * | 2001-03-29 | 2003-02-13 | Topo Target Aps | Succinimide and maleimide derivatives and their use as topoisomerase II catalytic inhibitors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05310685A (ja) | 1992-04-30 | 1993-11-22 | Teijin Ltd | 光学活性２―置換―２―シクロペンテノン類及びその製造方法 |
| JP3859270B2 (ja) | 1996-07-26 | 2006-12-20 | 森永乳業株式会社 | アポトーシス誘導剤 |
| KR100570936B1 (ko) * | 1997-03-05 | 2006-04-13 | 다카라 바이오 가부시키가이샤 | 시클로펜텐 고리 또는 시클로펜탄 고리를 갖는 화합물 |
| TW550263B (en) | 1998-09-01 | 2003-09-01 | Nissan Chemical Ind Ltd | Method for reducing an organic solvent remaining in tris-(2,3-epoxypropyl)-isocyanurate crystals |
-
1999
- 1999-08-10 CN CNB998122610A patent/CN1225472C/zh not_active Expired - Fee Related
- 1999-08-10 DE DE69906759T patent/DE69906759T2/de not_active Expired - Fee Related
- 1999-08-10 EP EP99937011A patent/EP1106624B1/en not_active Expired - Lifetime
- 1999-08-10 US US09/762,265 patent/US6380262B1/en not_active Expired - Fee Related
- 1999-08-10 WO PCT/JP1999/004324 patent/WO2000011021A1/ja not_active Ceased
- 1999-08-10 AU AU51958/99A patent/AU5195899A/en not_active Abandoned
- 1999-08-10 ES ES99937011T patent/ES2191446T3/es not_active Expired - Lifetime
- 1999-08-10 AT AT99937011T patent/ATE236927T1/de not_active IP Right Cessation
- 1999-08-10 KR KR1020017001625A patent/KR20010072317A/ko not_active Ceased
- 1999-08-13 TW TW088113894A patent/TWI238828B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69906759T2 (de) | 2004-03-18 |
| WO2000011021A1 (fr) | 2000-03-02 |
| EP1106624A1 (en) | 2001-06-13 |
| AU5195899A (en) | 2000-03-14 |
| ATE236927T1 (de) | 2003-04-15 |
| CN1323315A (zh) | 2001-11-21 |
| US6380262B1 (en) | 2002-04-30 |
| EP1106624B1 (en) | 2003-04-09 |
| EP1106624A4 (en) | 2001-11-21 |
| CN1225472C (zh) | 2005-11-02 |
| KR20010072317A (ko) | 2001-07-31 |
| DE69906759D1 (de) | 2003-05-15 |
| TWI238828B (en) | 2005-09-01 |
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