ATE238300T1 - (3,4-dihydro-2h-benzo(1,4)oxazinyl-methyl)-3-(1 - indol-3-yl)-alkylamine - Google Patents
(3,4-dihydro-2h-benzo(1,4)oxazinyl-methyl)-3-(1 - indol-3-yl)-alkylamineInfo
- Publication number
- ATE238300T1 ATE238300T1 AT00902331T AT00902331T ATE238300T1 AT E238300 T1 ATE238300 T1 AT E238300T1 AT 00902331 T AT00902331 T AT 00902331T AT 00902331 T AT00902331 T AT 00902331T AT E238300 T1 ATE238300 T1 AT E238300T1
- Authority
- AT
- Austria
- Prior art keywords
- oxazinyl
- alkylamines
- indol
- benzo
- dihydro
- Prior art date
Links
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 208000025966 Neurological disease Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000000926 neurological effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22683199A | 1999-01-07 | 1999-01-07 | |
| PCT/US2000/000230 WO2000040580A1 (en) | 1999-01-07 | 2000-01-06 | 3,4-dihydro-2h-benzo[1,4]oxazinyl-methyl[3-(1h-indol-3-yl)-alkyl]-amines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE238300T1 true ATE238300T1 (de) | 2003-05-15 |
Family
ID=22850596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00902331T ATE238300T1 (de) | 1999-01-07 | 2000-01-06 | (3,4-dihydro-2h-benzo(1,4)oxazinyl-methyl)-3-(1 - indol-3-yl)-alkylamine |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1140925B1 (de) |
| JP (1) | JP2002534427A (de) |
| CN (1) | CN1335845A (de) |
| AT (1) | ATE238300T1 (de) |
| AU (1) | AU2406700A (de) |
| CA (1) | CA2355308A1 (de) |
| DE (1) | DE60002292T2 (de) |
| DK (1) | DK1140925T3 (de) |
| ES (1) | ES2193047T3 (de) |
| PT (1) | PT1140925E (de) |
| TW (1) | TW546299B (de) |
| WO (1) | WO2000040580A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1478092A (zh) * | 2000-10-26 | 2004-02-25 | ʷ | 苯并噁嗪酮衍生物及其制备和应用 |
| JP2004531506A (ja) | 2001-03-29 | 2004-10-14 | ブリストル−マイヤーズ スクイブ カンパニー | 選択的なセロトニン再取り込みインヒビターとしてのシクロプロピルインドール誘導体 |
| WO2004106298A1 (en) * | 2003-05-30 | 2004-12-09 | Janssen Pharmaceutica N.V. | Indole derivatives with an improved antipsychotic activity |
| MX2007000480A (es) | 2004-07-15 | 2007-03-29 | Japan Tobacco Inc | Compuesto de benzamida fusionado e inhibidor de actividad de receptor de vainilloide 1. |
| JP2008521771A (ja) | 2004-11-26 | 2008-06-26 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 改良された抗精神病活性および抗不安症活性を有するイソキサゾリン−インドール誘導体 |
| US7906508B2 (en) | 2005-12-28 | 2011-03-15 | Japan Tobacco Inc. | 3,4-dihydrobenzoxazine compounds and inhibitors of vanilloid receptor subtype 1 (VRI) activity |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8803419D0 (en) * | 1988-02-15 | 1988-03-16 | Erba Carlo Spa | 1 4-benzoxazine & 1 4-benzothiazine derivatives & process for their preparation |
| JP2002510682A (ja) * | 1998-04-08 | 2002-04-09 | アメリカン・ホーム・プロダクツ・コーポレイション | うつ病治療用のインドール−３−イル−シクロヘキシルアミン誘導体（５−ｈｔ１受容体拮抗薬） |
-
2000
- 2000-01-05 TW TW089100094A patent/TW546299B/zh active
- 2000-01-06 ES ES00902331T patent/ES2193047T3/es not_active Expired - Lifetime
- 2000-01-06 CN CN00802505A patent/CN1335845A/zh active Pending
- 2000-01-06 WO PCT/US2000/000230 patent/WO2000040580A1/en not_active Ceased
- 2000-01-06 DE DE60002292T patent/DE60002292T2/de not_active Expired - Fee Related
- 2000-01-06 CA CA002355308A patent/CA2355308A1/en not_active Abandoned
- 2000-01-06 DK DK00902331T patent/DK1140925T3/da active
- 2000-01-06 JP JP2000592288A patent/JP2002534427A/ja active Pending
- 2000-01-06 AT AT00902331T patent/ATE238300T1/de not_active IP Right Cessation
- 2000-01-06 PT PT00902331T patent/PT1140925E/pt unknown
- 2000-01-06 AU AU24067/00A patent/AU2406700A/en not_active Abandoned
- 2000-01-06 EP EP00902331A patent/EP1140925B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002534427A (ja) | 2002-10-15 |
| EP1140925B1 (de) | 2003-04-23 |
| WO2000040580A1 (en) | 2000-07-13 |
| DK1140925T3 (da) | 2003-08-11 |
| EP1140925A1 (de) | 2001-10-10 |
| DE60002292D1 (de) | 2003-05-28 |
| PT1140925E (pt) | 2003-08-29 |
| DE60002292T2 (de) | 2003-10-23 |
| AU2406700A (en) | 2000-07-24 |
| CA2355308A1 (en) | 2000-07-13 |
| CN1335845A (zh) | 2002-02-13 |
| ES2193047T3 (es) | 2003-11-01 |
| TW546299B (en) | 2003-08-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1140925 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |