ATE238300T1 - (3,4-dihydro-2h-benzo(1,4)oxazinyl-methyl)-3-(1 - indol-3-yl)-alkylamine - Google Patents

(3,4-dihydro-2h-benzo(1,4)oxazinyl-methyl)-3-(1 - indol-3-yl)-alkylamine

Info

Publication number: ATE238300T1
Authority: AT; Austria
Prior art keywords: oxazinyl; alkylamines; indol; benzo; dihydro
Prior art date: 1999-01-07

Application number

AT00902331T

Other languages

English (en)

Inventor

Richard Eric Mewshaw

Dahui Zhou

Ping Zhou

Original Assignee

Wyeth Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-01-07

Filing date

2000-01-06

Publication date

2003-05-15

2000-01-06 Application filed by Wyeth Corp filed Critical Wyeth Corp

2003-05-15 Application granted granted Critical

2003-05-15 Publication of ATE238300T1 publication Critical patent/ATE238300T1/de

Links

125000004432 carbon atom Chemical group C* 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
208000012902 Nervous system disease Diseases 0.000 abstract 1
208000025966 Neurological disease Diseases 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
230000000926 neurological effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Indole Compounds (AREA)

AT00902331T 1999-01-07 2000-01-06 (3,4-dihydro-2h-benzo(1,4)oxazinyl-methyl)-3-(1 - indol-3-yl)-alkylamine ATE238300T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US22683199A	1999-01-07	1999-01-07
PCT/US2000/000230 WO2000040580A1 (en)	1999-01-07	2000-01-06	3,4-dihydro-2h-benzo[1,4]oxazinyl-methyl[3-(1h-indol-3-yl)-alkyl]-amines

Publications (1)

Publication Number	Publication Date
ATE238300T1 true ATE238300T1 (de)	2003-05-15

Family

ID=22850596

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00902331T ATE238300T1 (de)	1999-01-07	2000-01-06	(3,4-dihydro-2h-benzo(1,4)oxazinyl-methyl)-3-(1 - indol-3-yl)-alkylamine

Country Status (12)

Country	Link
EP (1)	EP1140925B1 (de)
JP (1)	JP2002534427A (de)
CN (1)	CN1335845A (de)
AT (1)	ATE238300T1 (de)
AU (1)	AU2406700A (de)
CA (1)	CA2355308A1 (de)
DE (1)	DE60002292T2 (de)
DK (1)	DK1140925T3 (de)
ES (1)	ES2193047T3 (de)
PT (1)	PT1140925E (de)
TW (1)	TW546299B (de)
WO (1)	WO2000040580A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6939871B2 (en) *	2000-10-26	2005-09-06	Smithkline Beecham P.L.C.	Benzoxazinone derivatives, their preparation and use
CZ20032644A3 (en)	2001-03-29	2004-06-16	Bristol-Myers Squibb Company	Cyclopropylindole derivatives as selective serotonin reuptake inhibitors
WO2004106298A1 (en) *	2003-05-30	2004-12-09	Janssen Pharmaceutica N.V.	Indole derivatives with an improved antipsychotic activity
KR101042490B1 (ko)	2004-07-15	2011-06-16	니뽄 다바코 산교 가부시키가이샤	축합 벤즈아미드 화합물 및 바닐로이드 수용체 1형(ｖｒ1)활성 저해제
ES2331144T3 (es)	2004-11-26	2009-12-22	Janssen Pharmaceutica Nv	Derivados de isoxazolina-indol con actividad antipsicotica y ansiolitica mejorada.
US7906508B2 (en)	2005-12-28	2011-03-15	Japan Tobacco Inc.	3,4-dihydrobenzoxazine compounds and inhibitors of vanilloid receptor subtype 1 (VRI) activity

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8803419D0 (en) *	1988-02-15	1988-03-16	Erba Carlo Spa	1 4-benzoxazine & 1 4-benzothiazine derivatives & process for their preparation
CN1304409A (zh) *	1998-04-08	2001-07-18	美国家用产品公司	用于治疗抑郁症的吲哚－3－基－环己胺衍生物(5－ht1受体拮抗剂)

2000
- 2000-01-05 TW TW089100094A patent/TW546299B/zh active
- 2000-01-06 DK DK00902331T patent/DK1140925T3/da active
- 2000-01-06 CA CA002355308A patent/CA2355308A1/en not_active Abandoned
- 2000-01-06 JP JP2000592288A patent/JP2002534427A/ja active Pending
- 2000-01-06 PT PT00902331T patent/PT1140925E/pt unknown
- 2000-01-06 AU AU24067/00A patent/AU2406700A/en not_active Abandoned
- 2000-01-06 DE DE60002292T patent/DE60002292T2/de not_active Expired - Fee Related
- 2000-01-06 CN CN00802505A patent/CN1335845A/zh active Pending
- 2000-01-06 EP EP00902331A patent/EP1140925B1/de not_active Expired - Lifetime
- 2000-01-06 ES ES00902331T patent/ES2193047T3/es not_active Expired - Lifetime
- 2000-01-06 AT AT00902331T patent/ATE238300T1/de not_active IP Right Cessation
- 2000-01-06 WO PCT/US2000/000230 patent/WO2000040580A1/en not_active Ceased

Also Published As

Publication number	Publication date
EP1140925B1 (de)	2003-04-23
CN1335845A (zh)	2002-02-13
WO2000040580A1 (en)	2000-07-13
TW546299B (en)	2003-08-11
JP2002534427A (ja)	2002-10-15
EP1140925A1 (de)	2001-10-10
DE60002292T2 (de)	2003-10-23
ES2193047T3 (es)	2003-11-01
CA2355308A1 (en)	2000-07-13
PT1140925E (pt)	2003-08-29
DE60002292D1 (de)	2003-05-28
AU2406700A (en)	2000-07-24
DK1140925T3 (da)	2003-08-11

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Legal Events

Date

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2003-10-15

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Publication of translation of european patent specification

Ref document number: 1140925

Country of ref document: EP

2005-10-15

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Ceased due to non-payment of the annual fee