ES2193159T3 - Una formulacion de factor de coagulacion viii. - Google Patents

Una formulacion de factor de coagulacion viii.

Info

Publication number
ES2193159T3
ES2193159T3 ES94915722T ES94915722T ES2193159T3 ES 2193159 T3 ES2193159 T3 ES 2193159T3 ES 94915722 T ES94915722 T ES 94915722T ES 94915722 T ES94915722 T ES 94915722T ES 2193159 T3 ES2193159 T3 ES 2193159T3
Authority
ES
Spain
Prior art keywords
factor viii
formulation
administration
subcutaneous
coagulation factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94915722T
Other languages
English (en)
Other versions
ES2193159T5 (es
Inventor
Jack Spira
Lars Widlund
Thomas Osterberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Swedish Orphan Biovitrum AB
Original Assignee
Biovitrum AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20390516&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2193159(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biovitrum AB filed Critical Biovitrum AB
Publication of ES2193159T3 publication Critical patent/ES2193159T3/es
Application granted granted Critical
Publication of ES2193159T5 publication Critical patent/ES2193159T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UNA FORMULACION FARMACEUTICA PARA ADMINISTRACION SUBCUTANEA, INTRAMUSCULAR O INTRADERMICA QUE COMPRENDE FACTOR VIII DE COAGULACION RECOMBINANTE Y UTILIZACION DEL MISMO PARA FABRICAR MEDICAMENTOS PARA EL TRATAMIENTO DE LA HEMOFILIA. LA FORMULACION COMPRENDE UN FACTOR VIII DE COAGULACION RECOMBINANTE ALTAMENTE PURIFICADO EN UNA CONCENTRACION DE AL MENOS 1000 IU/ML, QUE DA SORPRENDENTEMENTE ALTOS NIVELES FACTOR VIII ACTIVO EN LA CORRIENTE SANGUINEA DESPUES DE LA ADMINISTRACION SUBCUTANEA, INTRAMUSCULAR O INTRADERMICA. LA FORMULACION ESTA PENSADA PARA EL TRATAMIENTO DE LA HEMOFILIA POR ADMINISTRACION SUBCUTANEA, INTRAMUSCULAR O INTRADERMICA. EL FACTOR VIII RECOMBINANTE ES PREFERIBLEMENTE UN DERIVADO DE SUPRESION DEL MISMO, QUE PUEDE SER UTILIZADO PARA LA FABRICACION DE UN MEDICAMENTO PARA ADMINISTRACION SUBCUTANEA.
ES94915722T 1993-07-05 1994-03-31 Una formulación de factor de coagulación viii. Expired - Lifetime ES2193159T5 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9302308 1993-07-05
SE9302308A SE504074C2 (sv) 1993-07-05 1993-07-05 Proteinberedning för subkutan, intramuskulär eller intradermal administrering

Publications (2)

Publication Number Publication Date
ES2193159T3 true ES2193159T3 (es) 2003-11-01
ES2193159T5 ES2193159T5 (es) 2011-07-29

Family

ID=20390516

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94915722T Expired - Lifetime ES2193159T5 (es) 1993-07-05 1994-03-31 Una formulación de factor de coagulación viii.

Country Status (14)

Country Link
US (1) US5972885A (es)
EP (1) EP0710114B2 (es)
JP (1) JP3827713B2 (es)
AT (1) ATE233099T1 (es)
AU (1) AU6762794A (es)
CA (1) CA2163112C (es)
DE (1) DE69432179T3 (es)
DK (1) DK0710114T4 (es)
ES (1) ES2193159T5 (es)
MX (1) MX9402339A (es)
PT (1) PT710114E (es)
SE (2) SE504074C2 (es)
WO (1) WO1995001804A1 (es)
ZA (1) ZA942035B (es)

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CA2163112A1 (en) 1995-01-19
SE504074C2 (sv) 1996-11-04
DK0710114T4 (da) 2011-07-11
EP0710114B1 (en) 2003-02-26
JP3827713B2 (ja) 2006-09-27
US5972885A (en) 1999-10-26
DE69432179D1 (de) 2003-04-03
MX9402339A (es) 1995-01-31
ATE233099T1 (de) 2003-03-15
DK0710114T3 (da) 2003-06-23
WO1995001804A1 (en) 1995-01-19
SE9401105D0 (sv) 1994-03-31
DE69432179T3 (de) 2012-01-19
AU6762794A (en) 1995-02-06
JPH09500624A (ja) 1997-01-21
PT710114E (pt) 2003-06-30
SE9302308D0 (sv) 1993-07-05
SE9302308L (sv) 1995-01-06
ZA942035B (en) 1995-01-05
EP0710114B2 (en) 2011-03-16
EP0710114A1 (en) 1996-05-08
CA2163112C (en) 2007-08-07
ES2193159T5 (es) 2011-07-29
DE69432179T2 (de) 2003-07-24

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