ES2194049T3 - Factor-2 de crecimiento de queratinocitos. - Google Patents

Factor-2 de crecimiento de queratinocitos.

Info

Publication number
ES2194049T3
ES2194049T3 ES95911700T ES95911700T ES2194049T3 ES 2194049 T3 ES2194049 T3 ES 2194049T3 ES 95911700 T ES95911700 T ES 95911700T ES 95911700 T ES95911700 T ES 95911700T ES 2194049 T3 ES2194049 T3 ES 2194049T3
Authority
ES
Spain
Prior art keywords
polypeptide
kgf
keratinocit
stimulate
growth factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95911700T
Other languages
English (en)
Inventor
Joachim R Gruber
Patrick J Dillon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Priority claimed from EP95911700A external-priority patent/EP0815115B1/en
Application granted granted Critical
Publication of ES2194049T3 publication Critical patent/ES2194049T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factor [FGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE DESCRIBE UN POLIPEPTIDO HUMANO Y EL ADN (ARN) QUE LO CODIFICA, Y UN PROCEDIMIENTO PARA PRODUCIR ESTE POLIPEPTIDO MEDIANTE TECNICAS RECOMBINANTES. TAMBIEN SE DESCRIBEN PROCEDIMIENTOS PARA UTILIZAR DICHO POLIPEPTIDO PARA ESTIMULAR EL CRECIMIENTO DE CELULAS EPITELIALES QUE PUEDEN UTILIZARSE PARA ESTIMULAR LA CURACION DE HERIDAS, REDUCIR LA FORMACION DE CICATRICES Y EVITAR LA PERDIDA DE PELO. TAMBIEN SE DESCRIBEN ANTAGONISTAS DE ESTOS POLIPEPTIDOS Y SU UTILIZACION COMO UN AGENTE TERAPEUTICO PARA TRATAR ENFERMEDADES PROLIFERATIVAS TALES COMO EL CANCER, LA PSORIASIS, EL SARCOMA DE KAPOSI, LOS QUELOIDES, LA RETINOPATIA Y LA REESTENOSIS. TAMBIEN SE DESCRIBEN PROCEDIMIENTOS DE DIAGNOSTICO PARA DETECTAR MUTACIONES EN LA SECUENCIA CODIFICADORA DEL KGF KGF - 2 EN UNA MUESTRA DERIVADA DE UN HUESPED.
ES95911700T 1995-02-14 1995-02-14 Factor-2 de crecimiento de queratinocitos. Expired - Lifetime ES2194049T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP95911700A EP0815115B1 (en) 1995-02-14 1995-02-14 Keratinocyte growth factor-2

Publications (1)

Publication Number Publication Date
ES2194049T3 true ES2194049T3 (es) 2003-11-16

Family

ID=8222244

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95911700T Expired - Lifetime ES2194049T3 (es) 1995-02-14 1995-02-14 Factor-2 de crecimiento de queratinocitos.

Country Status (2)

Country Link
ES (1) ES2194049T3 (es)
PT (1) PT815115E (es)

Also Published As

Publication number Publication date
PT815115E (pt) 2003-10-31

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