ES2194231T3 - Una nueva forma de compuesto. - Google Patents

Una nueva forma de compuesto.

Info

Publication number
ES2194231T3
ES2194231T3 ES97951367T ES97951367T ES2194231T3 ES 2194231 T3 ES2194231 T3 ES 2194231T3 ES 97951367 T ES97951367 T ES 97951367T ES 97951367 T ES97951367 T ES 97951367T ES 2194231 T3 ES2194231 T3 ES 2194231T3
Authority
ES
Spain
Prior art keywords
compound
new form
invention refers
omeprozol
omeprazol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97951367T
Other languages
English (en)
Spanish (es)
Inventor
Martin Bohlin
Karol Horvath
Unge Sverker Von
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20405146&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2194231(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of ES2194231T3 publication Critical patent/ES2194231T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES97951367T 1996-12-20 1997-12-16 Una nueva forma de compuesto. Expired - Lifetime ES2194231T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9604793A SE510666C2 (sv) 1996-12-20 1996-12-20 Nya Kristallmodifikationer

Publications (1)

Publication Number Publication Date
ES2194231T3 true ES2194231T3 (es) 2003-11-16

Family

ID=20405146

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97951367T Expired - Lifetime ES2194231T3 (es) 1996-12-20 1997-12-16 Una nueva forma de compuesto.

Country Status (36)

Country Link
US (1) US6162816A (sr)
EP (1) EP0946547B1 (sr)
JP (1) JP4402174B2 (sr)
KR (1) KR20000069595A (sr)
CN (1) CN1109684C (sr)
AR (1) AR010361A1 (sr)
AT (1) ATE236898T1 (sr)
AU (1) AU730129B2 (sr)
BR (1) BR9714059A (sr)
CA (1) CA2274076C (sr)
CZ (1) CZ294784B6 (sr)
DE (1) DE69720774T2 (sr)
DK (1) DK0946547T3 (sr)
EE (1) EE03923B1 (sr)
EG (1) EG24414A (sr)
ES (1) ES2194231T3 (sr)
HU (1) HU227589B1 (sr)
ID (1) ID21850A (sr)
IL (1) IL130450A0 (sr)
IS (1) IS1981B (sr)
MY (1) MY117032A (sr)
NO (1) NO317191B1 (sr)
NZ (1) NZ336024A (sr)
PL (1) PL190377B1 (sr)
PT (1) PT946547E (sr)
RS (1) RS49685B (sr)
RU (1) RU2184734C2 (sr)
SA (1) SA97180739B1 (sr)
SE (1) SE510666C2 (sr)
SI (1) SI0946547T1 (sr)
SK (1) SK285151B6 (sr)
TR (1) TR199901410T2 (sr)
TW (1) TW538039B (sr)
UA (1) UA55436C2 (sr)
WO (1) WO1998028294A1 (sr)
ZA (1) ZA9711046B (sr)

Families Citing this family (60)

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US6699885B2 (en) 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6645988B2 (en) 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
SI20019A (sl) * 1998-07-13 2000-02-29 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Izboljšan postopek sinteze 5-metoksi -2-/(4-metoksi-3,5-dimetil-2-piridil)metil/ sulfinil-1H-benzimidazola
IL142703A (en) 1998-11-10 2006-04-10 Astrazeneca Ab Crystalline form of omeprazole
UA72748C2 (en) * 1998-11-10 2005-04-15 Astrazeneca Ab A novel crystalline form of omeprazole
JP3926936B2 (ja) 1998-11-16 2007-06-06 エーザイ・アール・アンド・ディー・マネジメント株式会社 スルホキシド誘導体・アセトン錯体およびその製造法
SE9804003D0 (sv) * 1998-11-23 1998-11-23 Astra Ab A method of producing drug particles
SE9900274D0 (sv) 1999-01-28 1999-01-28 Astra Ab New compound
JP2000344739A (ja) * 1999-06-01 2000-12-12 Sumitomo Chem Co Ltd Ｎ−保護−アゼチジン−２−カルボン酸の製造方法
TWI275587B (en) 1999-06-17 2007-03-11 Takeda Chemical Industries Ltd A crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
SE0000773D0 (sv) * 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
SE0000774D0 (sv) 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
CA2409044C (en) * 2000-05-15 2013-02-19 Takeda Chemical Industries, Ltd. Improved recrystallization processes for obtaining anhydrous optically active lansoprazole
GB0016040D0 (en) * 2000-06-29 2000-08-23 Glaxo Group Ltd Novel process for preparing crystalline particles
AU2001276721A1 (en) 2000-08-04 2002-02-18 Takeda Chemical Industries Ltd. Salts of benzimidazole compound and use thereof
SI20875A (sl) * 2001-04-25 2002-10-31 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Kristalna oblika omeprazola
DK1411900T4 (da) 2001-06-01 2014-01-27 Pozen Inc Farmaceutiske sammensætninger til den koordinerede frigørelse af NSAIDs
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
GB2376231A (en) 2001-06-06 2002-12-11 Cipla Ltd Benzimidazole-cyclodextrin inclusion complex
SE0102993D0 (sv) 2001-09-07 2001-09-07 Astrazeneca Ab New self emulsifying drug delivery system
WO2004002982A2 (en) * 2002-06-27 2004-01-08 Dr. Reddy's Laboratories Limited A process for preparation of optically pure or optically enriched sulfoxide compounds, including amorphous esomeprazole and salts thereof
CA2491118A1 (en) * 2002-06-27 2004-01-08 Dr. Reddy's Laboratories Limited A process for preparation of optically pure or optically enriched sulfoxide compounds, including amorphous esomeprazole and salts thereof
US7612098B2 (en) * 2002-08-30 2009-11-03 Dr. Reddy's Laboratories Limited Amorphous hydrous esomeprazole magnesium
US8697094B2 (en) 2002-10-16 2014-04-15 Takeda Pharmaceutical Company Limited Stable solid preparations
EA200500673A1 (ru) * 2002-10-22 2005-12-29 Рэнбакси Лабораториз Лимитед Аморфная форма соли эзомепразола, способ ее получения и фармацевтическая композиция на её основе
US20040242642A1 (en) * 2002-11-18 2004-12-02 Dr. Reddy's Laboratories Limited Crystalline esomeprazole compounds and process for the preparation thereof
US20060247277A1 (en) * 2003-02-28 2006-11-02 Yatendra Kumar Polymorphs of s-omeprazole
DE602004032524D1 (de) * 2003-03-24 2011-06-16 Eisai R&D Man Co Ltd Verfahren zur herstellung von amorphem rabeprazole-natrium-salz
WO2004099181A1 (en) * 2003-05-05 2004-11-18 Ranbaxy Laboratories Limited Barium salt of benzimidazole derivative
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
SE0400410D0 (sv) 2004-02-20 2004-02-20 Astrazeneca Ab New compounds
US8815916B2 (en) 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8461187B2 (en) 2004-06-16 2013-06-11 Takeda Pharmaceuticals U.S.A., Inc. Multiple PPI dosage form
BRPI0512522A (pt) 2004-06-24 2008-03-11 Astrazeneca Ab processo para a preparação de sal de sódio de esomeprazol, composto, formulação farmacêutica, e, método de tratamento
ES2246149B1 (es) * 2004-07-02 2007-06-01 Esteve Quimica, S.A. Formas solidas de la sal magnesica de s-omeprazol y procedimientos para su preparacion.
EP1885711A1 (en) * 2005-05-06 2008-02-13 Glenmark Pharmaceuticals Limited Esomeprazole strontium salt, process for its preparation and pharmaceutical compositions containing same
EP1907375B1 (en) * 2005-06-08 2013-07-24 LEK Pharmaceuticals d.d. Crystalline solvate of omeprazole sodium
WO2006134605A1 (en) * 2005-06-15 2006-12-21 Hetero Drugs Limited Amorphous esomeprazole hydrate
NL2000126C2 (nl) * 2005-07-15 2008-01-29 Solvay Werkwijze voor de vervaardiging van eptifibatide.
US20070043085A1 (en) * 2005-08-19 2007-02-22 Glenmark Pharmaceuticals Limited Process for the preparation of amorphous form of neutral esomeprazole
US7576219B2 (en) 2005-10-26 2009-08-18 Hanmi Pharm. Co., Ltd Crystalline S-omeprazole strontium hydrate, method for preparing same, and pharmaceutical composition containing same
EP1948637A4 (en) * 2005-11-14 2010-09-08 Hetero Drugs Ltd PROCESS FOR AMORPHES ESOMEPRAZOLE
US8124779B2 (en) * 2005-12-05 2012-02-28 Astrazeneca Ab Process for the preparation of esomeprazole non-salt form
EP1801110A1 (en) 2005-12-22 2007-06-27 KRKA, tovarna zdravil, d.d., Novo mesto Esomeprazole arginine salt
CA2631459A1 (en) 2005-12-28 2007-07-05 Union Quimico Farmaceutica, S.A. A process for the preparation of the (s)-enantiomer of omeprazole
EP2000468A1 (en) * 2007-05-09 2008-12-10 Dr. Reddy's Laboratories Ltd. Esomeprazole salts and processes for preparation thereof
US8106210B2 (en) 2007-10-08 2012-01-31 Hetero Drugs Limited Polymorphs of esomeprazole salts
LT2262790T (lt) 2008-03-10 2017-08-25 Takeda Pharmaceutical Company Limited Benzimidazolo junginio kristalas
EP2143722A1 (en) 2008-07-09 2010-01-13 Lek Pharmaceuticals D.D. Process for preparation of esomeprazole sodium of high chemical purity and new forms of esomeprazole sodium
KR20110079641A (ko) 2008-09-09 2011-07-07 아스트라제네카 아베 제약 조성물을 이를 필요로 하는 환자에게 전달하는 방법
MX2011013467A (es) 2009-06-25 2012-02-13 Astrazeneca Ab Metodo para tratar un paciente que corre el riesgo de desarollar una ulcera asociada a antiinflamatorio no esteroide (aine).
WO2011071982A2 (en) 2009-12-08 2011-06-16 Codexis, Inc. Synthesis of prazole compounds
DK2649187T3 (da) 2010-12-08 2018-01-29 Codexis Inc Biokatalysatorer og fremgangsmåder til syntesen af armodafinil
US9539214B2 (en) 2011-12-28 2017-01-10 Pozen Inc. Compositions and methods for delivery of omeprazole plus acetylsalicylic acid
RU2501549C1 (ru) 2012-08-30 2013-12-20 Авва Девелопмент Лтд Фармацевтическая композиция для лечения гастроэзофагеальной рефлюксной болезни
CN107043367A (zh) * 2017-05-26 2017-08-15 重庆莱美隆宇药业有限公司 一种中性s‑奥美拉唑的干燥工艺
JP2025532389A (ja) 2022-10-04 2025-09-29 ザビリュク，アルセニー 大動脈弁の石灰化の抑制

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
SE8301182D0 (sv) * 1983-03-04 1983-03-04 Haessle Ab Novel compounds
GB2189698A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
SE9002043D0 (sv) * 1990-06-07 1990-06-07 Astra Ab Improved method for synthesis
DE4035455A1 (de) * 1990-11-08 1992-05-14 Byk Gulden Lomberg Chem Fab Enantiomerentrennung
SE9301830D0 (sv) * 1993-05-28 1993-05-28 Ab Astra New compounds
US5877192A (en) * 1993-05-28 1999-03-02 Astra Aktiebolag Method for the treatment of gastric acid-related diseases and production of medication using (-) enantiomer of omeprazole
SE9302396D0 (sv) * 1993-07-09 1993-07-09 Ab Astra A novel compound form
DK1078628T3 (da) * 1994-07-08 2009-02-23 Astrazeneca Ab Tabletteret flerenhedsdoseringsform

Also Published As

Publication number Publication date
TW538039B (en) 2003-06-21
CZ220299A3 (cs) 2000-02-16
CA2274076A1 (en) 1998-07-02
US6162816A (en) 2000-12-19
AU730129B2 (en) 2001-02-22
SI0946547T1 (en) 2003-10-31
EG24414A (en) 2009-05-25
EP0946547B1 (en) 2003-04-09
CZ294784B6 (cs) 2005-03-16
EE9900259A (et) 2000-02-15
HU227589B1 (en) 2011-09-28
WO1998028294A1 (en) 1998-07-02
JP4402174B2 (ja) 2010-01-20
HK1022909A1 (en) 2000-08-25
AU5502698A (en) 1998-07-17
DE69720774D1 (de) 2003-05-15
PT946547E (pt) 2003-07-31
ID21850A (id) 1999-08-05
DK0946547T3 (da) 2003-06-30
SK285151B6 (sk) 2006-07-07
NZ336024A (en) 2001-02-23
IS5070A (is) 1999-06-07
AR010361A1 (es) 2000-06-07
TR199901410T2 (xx) 1999-08-23
JP2001507025A (ja) 2001-05-29
NO993068L (no) 1999-06-21
CA2274076C (en) 2008-09-30
ATE236898T1 (de) 2003-04-15
SE9604793L (sv) 1998-06-21
RS49685B (sr) 2007-11-15
CN1109684C (zh) 2003-05-28
SE510666C2 (sv) 1999-06-14
SK76599A3 (en) 1999-12-10
SE9604793D0 (sv) 1996-12-20
NO317191B1 (no) 2004-09-13
PL334297A1 (en) 2000-02-14
UA55436C2 (uk) 2003-04-15
YU28199A (sh) 2002-03-18
IS1981B (is) 2005-01-14
NO993068D0 (no) 1999-06-21
RU2184734C2 (ru) 2002-07-10
CN1241183A (zh) 2000-01-12
EP0946547A1 (en) 1999-10-06
BR9714059A (pt) 2000-05-09
HUP0001547A2 (hu) 2002-05-29
KR20000069595A (ko) 2000-11-25
EE03923B1 (et) 2002-12-16
ZA9711046B (en) 1998-06-22
DE69720774T2 (de) 2004-02-05
PL190377B1 (pl) 2005-12-30
SA97180739B1 (ar) 2006-05-20
MY117032A (en) 2004-04-30
IL130450A0 (en) 2000-06-01
HU0001547D0 (sr) 2002-05-29
HUP0001547A3 (en) 2002-06-28

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