ES2194997T3 - Procedimiento enzimatico para el desmucilaginado de aceites vegetales mediante fosfolipasa de aspergillus. - Google Patents
Procedimiento enzimatico para el desmucilaginado de aceites vegetales mediante fosfolipasa de aspergillus.Info
- Publication number
- ES2194997T3 ES2194997T3 ES96921886T ES96921886T ES2194997T3 ES 2194997 T3 ES2194997 T3 ES 2194997T3 ES 96921886 T ES96921886 T ES 96921886T ES 96921886 T ES96921886 T ES 96921886T ES 2194997 T3 ES2194997 T3 ES 2194997T3
- Authority
- ES
- Spain
- Prior art keywords
- vegetable oils
- procedure
- demucilagination
- phospholipase
- aspergillus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 4
- ZIIUUSVHCHPIQD-UHFFFAOYSA-N 2,4,6-trimethyl-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide Chemical compound CC1=CC(C)=CC(C)=C1S(=O)(=O)NC1=CC=CC(C(F)(F)F)=C1 ZIIUUSVHCHPIQD-UHFFFAOYSA-N 0.000 title abstract 2
- 241000228212 Aspergillus Species 0.000 title abstract 2
- 102000015439 Phospholipases Human genes 0.000 title abstract 2
- 108010064785 Phospholipases Proteins 0.000 title abstract 2
- 230000002255 enzymatic effect Effects 0.000 title abstract 2
- 235000015112 vegetable and seed oil Nutrition 0.000 title abstract 2
- 239000008158 vegetable oil Substances 0.000 title abstract 2
- UDPGUMQDCGORJQ-UHFFFAOYSA-N (2-chloroethyl)phosphonic acid Chemical compound OP(O)(=O)CCCl UDPGUMQDCGORJQ-UHFFFAOYSA-N 0.000 abstract 1
- 235000021152 breakfast Nutrition 0.000 abstract 1
- 238000004690 coupled electron pair approximation Methods 0.000 abstract 1
- 238000005238 degreasing Methods 0.000 abstract 1
- 239000008157 edible vegetable oil Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B3/00—Refining fats or fatty oils
- C11B3/003—Refining fats or fatty oils by enzymes or microorganisms, living or dead
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/913—Aspergillus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/913—Aspergillus
- Y10S435/917—Aspergillus niger
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/913—Aspergillus
- Y10S435/918—Aspergillus oryzae
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Fats And Perfumes (AREA)
- Edible Oils And Fats (AREA)
Abstract
LA INVENCION TRATA DE UNA ETAPA DEL PROCEDIMIENTO DE DESENGOMADO EN LA REDUCCION DE ACEITES COMESTIBLES, EN EL CUAL ACEITES VEGETALES, A LOS CUALES SE HA ELIMINADO DE MANERA PREFERENTE LOS FOSFATIDOS HIDRATABLES MEDIANTE UN PROCEDIMIENTO PREVIO ACUOSO DE DESENGOMADO, SE LIBERAN DE FOSFATIDOS NO HIDRATABLES MEDIANTE UN TRATAMIENTO ENZIMATICO, DE TAL MANERA QUE PUEDAN SER REFINADOS FISICAMENTE. LA PRINCIPAL CARACTERISTICA DE LA INVENCION ES LA UTILIZACION DE FOSFOLIPASA PROCEDENTE DE UNA CEPA DE ASPERGILLUS. EL PROCEDIMIENTO ES CUIDADOSO, ECONOMICO Y ECOLOGICO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19527274A DE19527274A1 (de) | 1995-07-26 | 1995-07-26 | Enzymatisches Verfahren zur Entschleimung von pflanzlichen Ölen mit Aspergillus-Phospholipase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2194997T3 true ES2194997T3 (es) | 2003-12-01 |
Family
ID=7767819
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES96921886T Expired - Lifetime ES2194997T3 (es) | 1995-07-26 | 1996-07-04 | Procedimiento enzimatico para el desmucilaginado de aceites vegetales mediante fosfolipasa de aspergillus. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6001640A (es) |
| EP (1) | EP0906379B1 (es) |
| JP (1) | JPH11510195A (es) |
| CN (1) | CN1074455C (es) |
| AR (1) | AR003052A1 (es) |
| AT (1) | ATE238406T1 (es) |
| BR (1) | BR9609816A (es) |
| CA (1) | CA2227568C (es) |
| CZ (1) | CZ298366B6 (es) |
| DE (2) | DE19527274A1 (es) |
| DK (1) | DK0906379T3 (es) |
| ES (1) | ES2194997T3 (es) |
| HU (1) | HU227760B1 (es) |
| MX (1) | MX9800547A (es) |
| PL (1) | PL185718B1 (es) |
| TR (1) | TR199800066T1 (es) |
| WO (1) | WO1997005219A1 (es) |
Families Citing this family (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6406723B1 (en) | 1997-04-09 | 2002-06-18 | Danisco A/S | Method for preparing flour doughs and products made from such doughs using glycerol oxidase and lipase |
| US6936289B2 (en) | 1995-06-07 | 2005-08-30 | Danisco A/S | Method of improving the properties of a flour dough, a flour dough improving composition and improved food products |
| US6103505A (en) * | 1996-12-09 | 2000-08-15 | Novo Nordisk A/S | Method for reducing phosphorus content of edible oils |
| WO1998026057A1 (en) * | 1996-12-09 | 1998-06-18 | Novo Nordisk A/S | Reduction of phosphorus containing components in edible oils comprising a high amount of non-hydratable phosphorus by use of a phospholipase, a phospholipase from a filamentous fungus having phospholipase a and/or b activity |
| DE19701348A1 (de) * | 1997-01-16 | 1998-07-23 | Roehm Gmbh | Protein mit Phospholipaseaktivität |
| ATE231186T1 (de) | 1998-07-21 | 2003-02-15 | Danisco | Lebensmittel |
| WO2002094123A2 (en) | 2001-05-18 | 2002-11-28 | Danisco A/S | Method of preparing a dought with an enzime |
| WO2003039264A1 (en) * | 2001-11-06 | 2003-05-15 | Novozymes North America, Inc. | Modified whey protein compositions having improved foaming properties |
| EP1497418B1 (en) | 2002-04-19 | 2012-10-17 | Verenium Corporation | Phospholipases, nucleic acids encoding them and methods for making and using them |
| US7943360B2 (en) | 2002-04-19 | 2011-05-17 | Verenium Corporation | Phospholipases, nucleic acids encoding them and methods for making and using them |
| US7226771B2 (en) | 2002-04-19 | 2007-06-05 | Diversa Corporation | Phospholipases, nucleic acids encoding them and methods for making and using them |
| WO2003102118A2 (en) * | 2002-05-30 | 2003-12-11 | Council Of Scientific And Industrial Research | Process for the pre-treatment of vegetable oils for physical refining |
| US7955814B2 (en) | 2003-01-17 | 2011-06-07 | Danisco A/S | Method |
| US20050196766A1 (en) | 2003-12-24 | 2005-09-08 | Soe Jorn B. | Proteins |
| MXPA05007654A (es) | 2003-01-17 | 2005-09-30 | Danisco | Metodo. |
| CA2515583C (en) | 2003-03-07 | 2015-07-14 | Diversa Corporation | Hydrolases, nucleic acids encoding them and methods for making and using them |
| RU2347804C2 (ru) * | 2003-12-19 | 2009-02-27 | Банджи Оилс, Инк. | Способ ферментативного удаления слизи из растительных масел и снижения нарастания на технологическом оборудовании |
| US7906307B2 (en) | 2003-12-24 | 2011-03-15 | Danisco A/S | Variant lipid acyltransferases and methods of making |
| GB0716126D0 (en) | 2007-08-17 | 2007-09-26 | Danisco | Process |
| US7718408B2 (en) | 2003-12-24 | 2010-05-18 | Danisco A/S | Method |
| GB0405637D0 (en) | 2004-03-12 | 2004-04-21 | Danisco | Protein |
| AU2005264938B2 (en) | 2004-06-16 | 2011-11-24 | Verenium Corporation | Compositions and methods for enzymatic decolorization of chlorophyll |
| US20080070291A1 (en) | 2004-06-16 | 2008-03-20 | David Lam | Compositions and Methods for Enzymatic Decolorization of Chlorophyll |
| CN102533440B (zh) | 2004-07-16 | 2017-09-19 | 杜邦营养生物科学有限公司 | 用酶使油脱胶的方法 |
| WO2006031699A2 (en) | 2004-09-10 | 2006-03-23 | Diversa Corporation | Compositions and methods for making and modifying oils |
| US20070148311A1 (en) * | 2005-12-22 | 2007-06-28 | Bunge Oils, Inc. | Phytosterol esterification product and method of make same |
| EP1987142A4 (en) | 2006-02-02 | 2009-07-15 | Verenium Corp | ESTERASES AND ASSOCIATED NUCLEIC ACIDS AND METHODS |
| CN100441668C (zh) * | 2006-06-09 | 2008-12-10 | 中国农业科学院油料作物研究所 | 超声波强化生物酶油脂脱胶的方法 |
| EP2057274B1 (en) | 2006-09-21 | 2013-12-11 | DSM IP Assets B.V. | Phospholipases, nucleic acids encoding them and methods for making and using them |
| CA2673954C (en) | 2007-01-25 | 2015-09-15 | Danisco A/S | Production of a lipid acyltransferase from transformed bacillus licheniformis cells |
| US8956853B2 (en) * | 2007-01-30 | 2015-02-17 | Bunge Oils, Inc. | Enzymatic degumming utilizing a mixture of PLA and PLC phospholipases |
| US8460905B2 (en) * | 2007-09-11 | 2013-06-11 | Bunge Oils, Inc. | Enzymatic degumming utilizing a mixture of PLA and PLC phospholipases with reduced reaction time |
| WO2008137846A2 (en) * | 2007-05-04 | 2008-11-13 | Akermin, Inc. | Immobilized enzymes and uses thereof |
| US8076123B2 (en) * | 2007-10-26 | 2011-12-13 | Oilseeds Biorefinery Corporation | Emulsification-free degumming of oil |
| US8241876B2 (en) | 2008-01-07 | 2012-08-14 | Bunge Oils, Inc. | Generation of triacylglycerols from gums |
| US8911808B2 (en) | 2008-06-23 | 2014-12-16 | Cavitation Technologies, Inc. | Method for cavitation-assisted refining, degumming and dewaxing of oil and fat |
| GB0904787D0 (en) * | 2009-03-20 | 2009-05-06 | Desmet Ballestra Engineering Sa | Improved enzymatic oil recuperation process |
| US11247964B2 (en) | 2009-05-01 | 2022-02-15 | Rrip, Llc | Method of processing phospholipid based lipid materials |
| AR077042A1 (es) | 2009-06-12 | 2011-07-27 | Danisco | Metodo para tratar una composicion que contiene pirofiofitina |
| UA111708C2 (uk) | 2009-10-16 | 2016-06-10 | Бандж Ойлз, Інк. | Спосіб рафінування олії |
| UA109884C2 (uk) | 2009-10-16 | 2015-10-26 | Поліпептид, що має активність ферменту фосфатидилінозитол-специфічної фосфоліпази с, нуклеїнова кислота, що його кодує, та спосіб його виробництва і застосування | |
| CN102844418B (zh) | 2010-03-12 | 2015-11-25 | 杜邦营养生物科学有限公司 | 方法 |
| EP2582809A1 (en) | 2010-06-17 | 2013-04-24 | DuPont Nutrition Biosciences ApS | Process |
| DE102010055159A1 (de) * | 2010-12-18 | 2012-06-21 | Lurgi Gmbh | Verfahren zur enzymatischen Reinigung von Ölen pflanzlicher oder tierischer Herkunft |
| AR085251A1 (es) | 2011-02-23 | 2013-09-18 | Danisco | Proceso para tratar aceite vegetal |
| CA2825632C (en) | 2011-02-23 | 2020-07-07 | Dupont Nutrition Biosciences Aps | Process for treating plant oil |
| CN102586011B (zh) * | 2011-12-01 | 2013-10-30 | 华中农业大学 | 一种利用磷脂酶a2进行植物油脂脱胶的方法 |
| WO2013104660A1 (en) | 2012-01-13 | 2013-07-18 | Dupont Nutrition Biosciences Aps | Process for treating a plant oil comprising hydrolysing chlorophyll or a chlorophyll derivative and involving partial caustic neutralisation |
| WO2013104659A2 (en) | 2012-01-13 | 2013-07-18 | Dupont Nutrition Biosciences Aps | Process |
| WO2013160374A1 (en) | 2012-04-27 | 2013-10-31 | Dupont Nutrition Biosciences Aps | Process for refining crude plant oil involving enzymatic hydrolysis and gum recycling |
| WO2013160372A1 (en) | 2012-04-27 | 2013-10-31 | Dupont Nutrition Biosciences Aps | Process for treating plant oil involving addition of serial doses of chlorophyll or chlorophyll derivative degrading enzyme |
| PE20150179A1 (es) | 2012-06-14 | 2015-02-07 | Bunge Global Innovation Llc | Proceso para la produccion de aceites bajos en acidos grasos saturados |
| WO2015017045A1 (en) | 2013-07-03 | 2015-02-05 | Keclon Sa | Modified bacillus cereus phospholipase c protein and method of processing vegetable oil |
| EP3119862B1 (en) | 2014-03-19 | 2022-09-07 | Novozymes A/S | Polypeptides having phospholipase c activity and polynucleotides encoding same |
| US20170121741A1 (en) | 2014-04-01 | 2017-05-04 | Dupont Nutrition Biosciences Aps | Method for increasing crude palm oil yields |
| CN106459934A (zh) | 2014-05-15 | 2017-02-22 | 诺维信公司 | 包括具有磷脂酶c活性的多肽的组合物及其应用 |
| US9453180B2 (en) | 2014-10-15 | 2016-09-27 | Arisdyne Systems, Inc. | Process for degumming oils |
| US9290717B1 (en) | 2014-12-15 | 2016-03-22 | Arisdyne Systems, Inc. | Reactor for degumming |
| EP3234081A1 (en) | 2014-12-19 | 2017-10-25 | DuPont Nutrition Biosciences ApS | Method of improving palm oil yields from palm fruit or palm fruit liquid |
| US9340749B1 (en) | 2015-05-06 | 2016-05-17 | Arisdyne Systems, Inc. | Method for degumming triglyceride oils |
| JP6061119B1 (ja) * | 2016-02-03 | 2017-01-18 | 不二製油株式会社 | ココアバター |
| WO2018186734A1 (en) | 2017-04-06 | 2018-10-11 | Purac Biochem B.V. | Enzymatic degumming of unrefined triglyceride oil |
| US10344246B2 (en) | 2017-05-24 | 2019-07-09 | Arisyne Systems, Inc. | Oil degumming systems |
| MY195363A (en) * | 2017-12-21 | 2023-01-16 | Purac Biochem Bv | Enzymatic Degumming of Unrefined Triglyceride Oil |
| WO2019215078A1 (en) | 2018-05-07 | 2019-11-14 | Dsm Ip Assets B.V. | Process for enzymatic oil degumming |
| CN109989115B (zh) * | 2019-04-28 | 2021-09-03 | 四川玉竹麻业有限公司 | 一种苎麻冷轧堆氧漂脱胶工艺 |
| CN110951621B (zh) * | 2019-11-18 | 2022-05-31 | 无锡优普克生物科技有限公司 | 一种产磷脂酶的黑曲霉菌株 |
| WO2023108233A1 (pt) * | 2021-12-16 | 2023-06-22 | Oliveira Jean Paulo De | Processo de reaproveitamento da lisogoma aplicado no pré-tratamento de óleos vegetais degomados para posterior tratamento enzimático e transesterificação do biodiesel |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61289884A (ja) * | 1985-06-14 | 1986-12-19 | Asahi Denka Kogyo Kk | リパ−ゼ類の製造方法 |
| GB8525012D0 (en) * | 1985-10-10 | 1985-11-13 | Cpc International Inc | Carbohydrate refining process |
| US5288619A (en) * | 1989-12-18 | 1994-02-22 | Kraft General Foods, Inc. | Enzymatic method for preparing transesterified oils |
| JPH04356191A (ja) * | 1990-07-10 | 1992-12-09 | Kanegafuchi Chem Ind Co Ltd | リン脂質の製造法 |
| JPH04356192A (ja) * | 1990-07-10 | 1992-12-09 | Kanegafuchi Chem Ind Co Ltd | リン脂質の製造方法 |
| DE4115938A1 (de) * | 1991-05-16 | 1992-11-19 | Metallgesellschaft Ag | Enzymatisches verfahren zur verminderung des gehaltes an phosphorhaltigen bestandteilen in pflanzlichen und tierischen oelen |
| DK0546215T3 (da) * | 1991-12-12 | 1998-10-19 | Nestle Sa | Varmestabil olie-i-vandemulsion og proces til dens fremstilling |
| PT575133E (pt) * | 1992-06-16 | 2002-11-29 | Sankyo Co | Nova fosfolipase a1 processo para a sua preparacao e sua utilizacao |
| JP2937746B2 (ja) * | 1993-04-25 | 1999-08-23 | 昭和産業株式会社 | 油脂の精製方法 |
| JP2657887B2 (ja) * | 1993-05-24 | 1997-09-30 | 日清製油株式会社 | 固定化酵素の調製方法 |
-
1995
- 1995-07-26 DE DE19527274A patent/DE19527274A1/de not_active Ceased
-
1996
- 1996-07-04 CN CN96195847A patent/CN1074455C/zh not_active Expired - Fee Related
- 1996-07-04 DK DK96921886T patent/DK0906379T3/da active
- 1996-07-04 JP JP9507073A patent/JPH11510195A/ja active Pending
- 1996-07-04 PL PL96324648A patent/PL185718B1/pl not_active IP Right Cessation
- 1996-07-04 CZ CZ0022498A patent/CZ298366B6/cs not_active IP Right Cessation
- 1996-07-04 US US08/983,324 patent/US6001640A/en not_active Expired - Lifetime
- 1996-07-04 WO PCT/DE1996/001190 patent/WO1997005219A1/de not_active Ceased
- 1996-07-04 EP EP96921886A patent/EP0906379B1/de not_active Expired - Lifetime
- 1996-07-04 AT AT96921886T patent/ATE238406T1/de active
- 1996-07-04 CA CA002227568A patent/CA2227568C/en not_active Expired - Fee Related
- 1996-07-04 BR BR9609816A patent/BR9609816A/pt not_active Application Discontinuation
- 1996-07-04 TR TR1998/00066T patent/TR199800066T1/xx unknown
- 1996-07-04 DE DE59610388T patent/DE59610388D1/de not_active Expired - Lifetime
- 1996-07-04 ES ES96921886T patent/ES2194997T3/es not_active Expired - Lifetime
- 1996-07-04 HU HU9802813A patent/HU227760B1/hu not_active IP Right Cessation
- 1996-07-26 AR ARP960103765A patent/AR003052A1/es unknown
-
1998
- 1998-01-19 MX MX9800547A patent/MX9800547A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR9609816A (pt) | 1999-07-06 |
| US6001640A (en) | 1999-12-14 |
| PL185718B1 (pl) | 2003-07-31 |
| CZ298366B6 (cs) | 2007-09-12 |
| HUP9802813A2 (hu) | 1999-03-29 |
| CZ22498A3 (cs) | 1998-06-17 |
| HU227760B1 (en) | 2012-02-28 |
| CA2227568A1 (en) | 1997-02-13 |
| WO1997005219A1 (de) | 1997-02-13 |
| TR199800066T1 (xx) | 1998-04-21 |
| EP0906379B1 (de) | 2003-04-23 |
| JPH11510195A (ja) | 1999-09-07 |
| HUP9802813A3 (en) | 2000-03-28 |
| MX9800547A (es) | 1998-11-30 |
| CN1192231A (zh) | 1998-09-02 |
| CN1074455C (zh) | 2001-11-07 |
| DE19527274A1 (de) | 1997-01-30 |
| AR003052A1 (es) | 1998-05-27 |
| EP0906379A1 (de) | 1999-04-07 |
| PL324648A1 (en) | 1998-06-08 |
| HK1015819A1 (en) | 1999-10-22 |
| DK0906379T3 (da) | 2003-08-11 |
| DE59610388D1 (de) | 2003-05-28 |
| ATE238406T1 (de) | 2003-05-15 |
| CA2227568C (en) | 2006-05-30 |
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