ES2196086T3 - Sistema de control del chorro de un citometro de flujo. - Google Patents

Sistema de control del chorro de un citometro de flujo.

Info

Publication number
ES2196086T3
ES2196086T3 ES95937545T ES95937545T ES2196086T3 ES 2196086 T3 ES2196086 T3 ES 2196086T3 ES 95937545 T ES95937545 T ES 95937545T ES 95937545 T ES95937545 T ES 95937545T ES 2196086 T3 ES2196086 T3 ES 2196086T3
Authority
ES
Spain
Prior art keywords
jet
substance
monitoring
well
flow cytometer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95937545T
Other languages
English (en)
Inventor
Den Engh Ger Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Washington
Original Assignee
University of Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Washington filed Critical University of Washington
Application granted granted Critical
Publication of ES2196086T3 publication Critical patent/ES2196086T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G01N2015/1406—Control of droplet point

Landscapes

  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

UN MONITOR DE CHORRO DIRECTO (66) ILUMINA EL CHORRO DE UN CITOMETRO DE FLUJO EN UNA BANDA DE LONGITUD DE ONDA DE MONITORIZACION QUE ESTA SUBSTANCIALMENTE SEPARADA DE LA BANDA DE LONGITUD DE ONDA DE LA SUBSTANCIA. CUANDO SE UTILIZA UN LASER PARA PROVOCAR LA FLUORESCENCIA DE LA SUBSTANCIA, ESTE PUEDE SER APROPIADO PARA UTILIZAR UNA FUENTE INFRARROJA (67) PARA ILUMINAR EL CHORRO Y DE ESTA FORMA MONITORIZAR OPTICAMENTE LAS CONDICIONES DENTRO DEL CHORRO A TRAVES DE UNA CAMARA CCD (68) O SIMILAR. ESTA MONITORIZACION OPTICA PUEDE SUMINISTRARSE PARA ALGUNOS TIPOS DE SISTEMAS DE CONTROLADOR O DE REALIMENTACION (34) QUE CAMBIE AUTOMATICAMENTE BIEN LA UBICACION HORIZONTAL DEL CHORRO, BIEN EL PUNTO EN EL CUAL SE PRODUCE LA SEPARACION DE GOTAS, O BIEN ALGUNA OTRA CONDICION DENTRO DEL CHORRO PARA MANTENER UNAS CONDICIONES OPTIMAS. EL DISPOSITIVO DE MONITORIZACION DE CHORRO DIRECTO (66) PUEDE SER ACCIONADO SIMULTANEAMENTE CON EL SISTEMA DE DETECCION Y ANALISIS DE LAS PROPIEDADES DE LA SUBSTANCIA DE MANERAQUE PUEDE CONSEGUIRSE UNA MONITORIZACION CONTINUA SIN INTERFERIR CON LA RECOGIDA DE DATOS DE LA SUBSTANCIA Y PUEDE CONFIGURARSE DE MANERA QUE PERMITA QUE EL FRENTE DEL ANALISIS O EL AREA DE CAIDA LIBRE (7) NO SEAN OBSTRUIDOS DURANTE EL PROCESAMIENTO.
ES95937545T 1994-10-14 1995-10-13 Sistema de control del chorro de un citometro de flujo. Expired - Lifetime ES2196086T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/323,352 US5602039A (en) 1994-10-14 1994-10-14 Flow cytometer jet monitor system

Publications (1)

Publication Number Publication Date
ES2196086T3 true ES2196086T3 (es) 2003-12-16

Family

ID=23258849

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95937545T Expired - Lifetime ES2196086T3 (es) 1994-10-14 1995-10-13 Sistema de control del chorro de un citometro de flujo.

Country Status (8)

Country Link
US (1) US5602039A (es)
EP (1) EP0786079B1 (es)
JP (1) JPH10507525A (es)
AU (1) AU691693B2 (es)
CA (1) CA2201332C (es)
DE (1) DE69530851T2 (es)
ES (1) ES2196086T3 (es)
WO (1) WO1996012172A1 (es)

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EP0786079B1 (en) 2003-05-21
DE69530851D1 (de) 2003-06-26
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