ES2200705A1 - Elemento regulador que activa la expresion genica en condiciones de baja tension de oxigeno y represion por glucosa. - Google Patents

Elemento regulador que activa la expresion genica en condiciones de baja tension de oxigeno y represion por glucosa.

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Publication number
ES2200705A1
ES2200705A1 ES200201930A ES200201930A ES2200705A1 ES 2200705 A1 ES2200705 A1 ES 2200705A1 ES 200201930 A ES200201930 A ES 200201930A ES 200201930 A ES200201930 A ES 200201930A ES 2200705 A1 ES2200705 A1 ES 2200705A1
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ES
Spain
Prior art keywords
regulatory element
gene expression
glucose
low voltage
oxygen conditions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES200201930A
Other languages
English (en)
Other versions
ES2200705B1 (es
Inventor
Gonzalez Antonio Llobell
Barera Manuel Rey
Chambergo Felipe Santiago
Barrera Manuel Rey
Alcalde Felipe Santi Chambergo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidade de São Paulo
Newbiotechnic SA
Original Assignee
Universidade de São Paulo
Newbiotechnic SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Universidade de São Paulo, Newbiotechnic SA filed Critical Universidade de São Paulo
Priority to ES200201930A priority Critical patent/ES2200705B1/es
Publication of ES2200705A1 publication Critical patent/ES2200705A1/es
Application granted granted Critical
Publication of ES2200705B1 publication Critical patent/ES2200705B1/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Abstract

Elemento regulador que activa la expresión génica en condiciones de baja tensión de oxígeno y represión por glucosa y aplicaciones. El elemento regulador activa la expresión del gen al que está operativamente fusionado en condiciones de baja tensión de oxígeno y alta concentración de glucosa en el medio de cultivo. Dicho elemento regulador puede utilizarse para construir cassettes de expresión, vectores y sistemas de expresión eucariotas susceptibles de ser regulados por acción del oxígeno y de no ser reprimidos por glucosa.
ES200201930A 2002-08-14 2002-08-14 Elemento regulador que activa la expresion genica en condiciones de baja tension de oxigeno y represion por glucosa y aplicaciones. Expired - Lifetime ES2200705B1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES200201930A ES2200705B1 (es) 2002-08-14 2002-08-14 Elemento regulador que activa la expresion genica en condiciones de baja tension de oxigeno y represion por glucosa y aplicaciones.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200201930A ES2200705B1 (es) 2002-08-14 2002-08-14 Elemento regulador que activa la expresion genica en condiciones de baja tension de oxigeno y represion por glucosa y aplicaciones.

Publications (2)

Publication Number Publication Date
ES2200705A1 true ES2200705A1 (es) 2004-03-01
ES2200705B1 ES2200705B1 (es) 2005-04-16

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ES200201930A Expired - Lifetime ES2200705B1 (es) 2002-08-14 2002-08-14 Elemento regulador que activa la expresion genica en condiciones de baja tension de oxigeno y represion por glucosa y aplicaciones.

Country Status (1)

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ES (1) ES2200705B1 (es)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9202983A (pt) * 1992-07-31 1994-02-01 Univ Sao Paulo Processo para melhoramento de producao de celulases atraves da aceleracao da inducao dos transcritos de celobiohidrolase i(cbh 1)e endoglucanase i(egl 1)em fungos celuloliticos
WO1994004673A1 (en) * 1992-08-19 1994-03-03 Alko Group Ltd. Fungal promoters active in the presence of glucose
EP0814162A2 (en) * 1996-06-21 1997-12-29 Hoechst Aktiengesellschaft Expression of the alpha-toxin gene (hla) of staphylococcus aureus using a chromosomally encoded hla-lacZ gene fusion
US5830692A (en) * 1995-03-24 1998-11-03 Consortium Fur Elektrochemische Industrie Gmbh Expression system which can be regulated

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9202983A (pt) * 1992-07-31 1994-02-01 Univ Sao Paulo Processo para melhoramento de producao de celulases atraves da aceleracao da inducao dos transcritos de celobiohidrolase i(cbh 1)e endoglucanase i(egl 1)em fungos celuloliticos
WO1994004673A1 (en) * 1992-08-19 1994-03-03 Alko Group Ltd. Fungal promoters active in the presence of glucose
US5830692A (en) * 1995-03-24 1998-11-03 Consortium Fur Elektrochemische Industrie Gmbh Expression system which can be regulated
EP0814162A2 (en) * 1996-06-21 1997-12-29 Hoechst Aktiengesellschaft Expression of the alpha-toxin gene (hla) of staphylococcus aureus using a chromosomally encoded hla-lacZ gene fusion

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ABRAHAO-NETO J et al. Mitochondrial Functions Mediate Cellulase Gene Expression in Trichoderma reesei. Biochemistry, 1995, Vol. 34, Nº 33, paginas 10456-10462, figura 3B. *
CHAMBERGO FS et al. Elucidation of the metabolic fate of glucose in the filamentous fungus Trichoderma reesei using expressed sequence tag (EST) analysis and CDNA microarrays. J. Biol. Chem., Abril 2002, Vol. 277, Nº 16, paginas 13983-8. *

Also Published As

Publication number Publication date
ES2200705B1 (es) 2005-04-16

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