ES2212758T1 - Preparacion de uso cutaneo. - Google Patents

Preparacion de uso cutaneo.

Info

Publication number
ES2212758T1
ES2212758T1 ES00940480T ES00940480T ES2212758T1 ES 2212758 T1 ES2212758 T1 ES 2212758T1 ES 00940480 T ES00940480 T ES 00940480T ES 00940480 T ES00940480 T ES 00940480T ES 2212758 T1 ES2212758 T1 ES 2212758T1
Authority
ES
Spain
Prior art keywords
plant extract
preparation
catalase
reductase
superoxide dismutase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES00940480T
Other languages
English (en)
Other versions
ES2212758T3 (es
Inventor
Christian Diehl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Life Science Investments Ltd
Original Assignee
Life Science Investments Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Life Science Investments Ltd filed Critical Life Science Investments Ltd
Publication of ES2212758T1 publication Critical patent/ES2212758T1/es
Application granted granted Critical
Publication of ES2212758T3 publication Critical patent/ES2212758T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44Oxidoreductases (1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44Oxidoreductases (1)
    • A61K38/446Superoxide dismutase (1.15)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11Encapsulated compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/731Cellulose; Quaternized cellulose derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/04Preparations for care of the skin for chemically tanning the skin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y111/00Oxidoreductases acting on a peroxide as acceptor (1.11)
    • C12Y111/01Peroxidases (1.11.1)
    • C12Y111/01006Catalase (1.11.1.6)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y115/00Oxidoreductases acting on superoxide as acceptor (1.15)
    • C12Y115/01Oxidoreductases acting on superoxide as acceptor (1.15) with NAD or NADP as acceptor (1.15.1)
    • C12Y115/01001Superoxide dismutase (1.15.1.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41Particular ingredients further characterized by their size
    • A61K2800/412Microsized, i.e. having sizes between 0.1 and 100 microns

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Birds (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)

Abstract

Preparación de uso cutáneo, que contiene excipientes y un vector medicamentoso encapsulando un extracto vegetal en reduciasa, catalasa y superóxido dismutasa, caracterizado: porque el vector medicamentoso, constituido por nanoesferas que encapsulan un extracto vegetal rico en reductasa, catalasa y superóxido dismutasa, representa entre el 1% y el 20% del peso de la preparación, porque el extracto vegetal utilizado es rico en reductasa, catalasa y superóxido dismutasa.

Claims (6)

1. Preparación de uso cutáneo, la cual comporta excipientes y un vector medicamentoso, el cual encapsula a un extracto vegetal rico en reductasa, catalasa y superóxido dismutasa, caracterizado:
- por el hecho de que, el vector medicamentoso, constituido por nanoesferas, que encapsula a un extracto vegetal, rico en reductasa, en catalasa y en superóxido de dismutasa, representa entre un 1% y un 20%, en peso, de la preparación,
- por el hecho de que, el extracto vegetal utilizado, es rico en reductasa, en catalasa y en superóxido dismutasa.
2. Preparación de uso cutáneo, según la reivindicación 1, caracterizado por el hecho de que, las nanoesferas en forma de partículas esféricas que encapsulan al extracto vegetal, poseen una membrana de colágeno y de glicosaminoglicanos.
3. Preparación de uso cutáneo, según una de las reivindicaciones 1 y 2, caracterizada por el hecho de que, la carga de extracto vegetal de las nanoesferas, representa entre el 5% y el 15%, en peso, de éstas.
4. Preparación de uso cutáneo, según la reivindicación 1, caracterizada por el hecho de que, el extracto vegetal retenido, debe tener las siguientes concentraciones enzimáticas:
\bullet reductasa: entre 100 U.I y 1.000 U.I.
\bullet catalasa: entre 100 U.I. y 1.000 U.I.
\bullet superóxido dismutasa: entre 500 U.I. y 5.000 U.I.
5. Preparación de uso cutáneo, según una de las reivindicaciones 1 a 4, caracterizada por el hecho de que, los excipientes, contienen una mezcla de aceites y de ácidos grasos, de agentes antioxidantes y de agentes conservantes.
6. Preparación de uso cutáneo, que contiene excipientes, vectores medicamentosos, que encapsulan a un extracto vegetal, rico en reductasa, catalasa y superóxido dismutasa, caracterizada por el hecho de que, ésta contiene, por 100 partes:
\bullet Del 1% al 20%, de una forma preferente, el 3%, de nanoesferas que encapsulan a un extracto vegetal rico en reductasa, catalasa y superóxido dismutasa;
\bullet 1% de agente conservante;
\bullet 0,1% de agente quelante, secuestrante de iones;
\bullet 0,3% de un agente gelificante a base de celulosa modificada;
\bullet 0,6% de un agente para ajustar el pH;
estando el resto, hasta el 100%, constituido por agua desmineralizada, y una combinación de excipientes de uso común para una aplicación cutánea.
ES00940480T 2000-06-09 2000-06-09 Preparacion de uso cutaneo. Expired - Lifetime ES2212758T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/FR2000/001601 WO2001093887A1 (fr) 2000-06-09 2000-06-09 Preparation a usage cutane

Publications (2)

Publication Number Publication Date
ES2212758T1 true ES2212758T1 (es) 2004-08-01
ES2212758T3 ES2212758T3 (es) 2005-11-01

Family

ID=8846806

Family Applications (1)

Application Number Title Priority Date Filing Date
ES00940480T Expired - Lifetime ES2212758T3 (es) 2000-06-09 2000-06-09 Preparacion de uso cutaneo.

Country Status (6)

Country Link
EP (1) EP1286679B8 (es)
AT (1) ATE294588T1 (es)
AU (1) AU5541100A (es)
DE (1) DE60019979T2 (es)
ES (1) ES2212758T3 (es)
WO (1) WO2001093887A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2891736B1 (fr) * 2005-10-12 2007-11-30 Gattefosse Sas Soc Par Actions Excipient comprenant un derive de cires pour la fabrication de formulations topiques cosmetiques
CN104116877A (zh) * 2014-08-11 2014-10-29 徐辉 一种治疗白癜风的外用搽剂及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0429915A (ja) * 1990-05-24 1992-01-31 Sunstar Inc 光破砕性リポソーム含有皮膚化粧料

Also Published As

Publication number Publication date
DE60019979D1 (de) 2005-06-09
DE60019979T2 (de) 2006-03-09
ES2212758T3 (es) 2005-11-01
WO2001093887A1 (fr) 2001-12-13
HK1055673A1 (en) 2004-01-21
EP1286679A1 (fr) 2003-03-05
AU5541100A (en) 2001-12-17
EP1286679B8 (fr) 2005-06-29
ATE294588T1 (de) 2005-05-15
EP1286679B1 (fr) 2005-05-04

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