ES2282301T3 - Inhibidores de tgf-beta y procedimientos. - Google Patents

Inhibidores de tgf-beta y procedimientos. Download PDF

Info

Publication number: ES2282301T3
Authority: ES; Spain
Prior art keywords: ala; peptide; glu; pro; methylalanine
Prior art date: 2000-09-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

ES01977301T

Other languages

English (en)

Spanish (es)

Inventor

Rajendra S. Bhatnagar

Craig A. Gough

Jing Jing Qian

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

University of California Berkeley

University of California San Diego UCSD

Original Assignee

University of California Berkeley

University of California San Diego UCSD

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-09-29

Filing date

2001-09-27

Publication date

2007-10-16

2001-09-27 Application filed by University of California Berkeley, University of California San Diego UCSD filed Critical University of California Berkeley

2007-10-16 Application granted granted Critical

2007-10-16 Publication of ES2282301T3 publication Critical patent/ES2282301T3/es

2021-09-27 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Immunology (AREA)
Dermatology (AREA)
Physical Education & Sports Medicine (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Biomedical Technology (AREA)
Surgery (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)

ES01977301T 2000-09-29 2001-09-27 Inhibidores de tgf-beta y procedimientos. Expired - Lifetime ES2282301T3 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US09/676,108 US6509318B1 (en)	2000-09-29	2000-09-29	TGF-B inhibitors and methods
US676108		2000-09-29

Publications (1)

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ES2282301T3 true ES2282301T3 (es)	2007-10-16

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ES01977301T Expired - Lifetime ES2282301T3 (es)	2000-09-29	2001-09-27	Inhibidores de tgf-beta y procedimientos.

Country Status (9)

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US (2)	US6509318B1 (de)
EP (1)	EP1320541B1 (de)
JP (1)	JP2004509931A (de)
AT (1)	ATE355297T1 (de)
AU (1)	AU2001296431A1 (de)
CA (1)	CA2421851A1 (de)
DE (1)	DE60126966T2 (de)
ES (1)	ES2282301T3 (de)
WO (1)	WO2002026935A2 (de)

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US6509318B1 (en) *	2000-09-29	2003-01-21	The Regents Of The University Of California	TGF-B inhibitors and methods
GB0217136D0 (en) *	2002-07-24	2002-09-04	Renovo Ltd	Wound healing & treatment of fibrosis
ES2304069B1 (es) *	2003-08-22	2009-08-12	Proyecto De Biomedicina Cima, S.L.	Peptidos con capacidad de unirse al factor transformante de crecimiento beta 1 (tgf-b1).
EP1740615B1 (de)	2004-03-31	2014-11-05	Genentech, Inc.	Humanisierte anti-tgf-beta-antikörper
US20060293227A1 (en) *	2005-06-24	2006-12-28	Bhatnagar Rajendra S	Cosmetic compositions and methods using transforming growth factor-beta mimics
US20060293228A1 (en) *	2005-06-24	2006-12-28	Bhatnagar Rajendra S	Therapeutic compositions and methods using transforming growth factor-beta mimics
EP2182969B1 (de)	2007-07-31	2016-11-16	The Board of Regents of The University of Texas System	miRNA-FAMILIE ALS FIBROSEMODULATOR UND IHRE VERWENDUNG
WO2010088778A1 (en) *	2009-02-09	2010-08-12	The Royal Institution For The Advancement Of Learning/Mcgill University	Cd109 polypeptides and uses thereof for the treatment of skin cells
PL2970890T3 (pl)	2013-03-14	2020-11-16	The Brigham And Women's Hospital, Inc.	Kompozycje i sposoby ekspansji i hodowli nabłonkowych komórek macierzystych
EP3189134A1 (de)	2014-09-03	2017-07-12	The Brigham and Women's Hospital, Inc.	Zusammensetzungen, systeme und verfahren zur erzeugung von innenohrhaarzellen zur behandlung von gehörverlust
EP3197474B1 (de)	2014-09-26	2023-06-07	Rajendra Sahai Bhatnagar	Inhibitoren der nf-kappa-b-aktivität zur behandlung von krankheiten und leiden
US10669528B2 (en)	2015-06-25	2020-06-02	Children's Medical Center Corporation	Methods and compositions relating to hematopoietic stem cell expansion, enrichment, and maintenance
US11021687B2 (en)	2016-01-08	2021-06-01	The Brigham And Women's Hospital, Inc.	Production of differentiated enteroendocrine cells and insulin producing cells
US10213511B2 (en)	2016-03-02	2019-02-26	Frequency Therapeutics, Inc.	Thermoreversible compositions for administration of therapeutic agents
US11260130B2 (en)	2016-03-02	2022-03-01	Frequency Therapeutics, Inc.	Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using a GSK3 inhibitor: IV
US10201540B2 (en)	2016-03-02	2019-02-12	Frequency Therapeutics, Inc.	Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using GSK3 inhibitors: I
EP4049665B1 (de)	2016-03-15	2025-03-12	The Children's Medical Center Corporation	Verfahren und zusammensetzungen im zusammenhang mit der expansion hämatopoetischer stammzellen
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2000
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2001
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- 2001-09-27 AU AU2001296431A patent/AU2001296431A1/en not_active Abandoned
- 2001-09-27 CA CA002421851A patent/CA2421851A1/en not_active Abandoned
- 2001-09-27 ES ES01977301T patent/ES2282301T3/es not_active Expired - Lifetime
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- 2001-09-27 EP EP01977301A patent/EP1320541B1/de not_active Expired - Lifetime
- 2001-09-27 JP JP2002530701A patent/JP2004509931A/ja not_active Withdrawn
- 2001-09-27 DE DE60126966T patent/DE60126966T2/de not_active Expired - Fee Related
2002
- 2002-11-25 US US10/304,586 patent/US20030083265A1/en not_active Abandoned

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Publication number	Publication date
JP2004509931A (ja)	2004-04-02
AU2001296431A1 (en)	2002-04-08
US6509318B1 (en)	2003-01-21
DE60126966D1 (de)	2007-04-12
WO2002026935A3 (en)	2002-06-27
WO2002026935A2 (en)	2002-04-04
EP1320541A4 (de)	2005-01-12
ATE355297T1 (de)	2006-03-15
EP1320541B1 (de)	2007-02-28
US20030083265A1 (en)	2003-05-01
EP1320541A2 (de)	2003-06-25
DE60126966T2 (de)	2008-04-10
CA2421851A1 (en)	2002-04-04

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