ES2322882B1 - Peptidos inhibidores de la exocitosis neuronal. - Google Patents

Peptidos inhibidores de la exocitosis neuronal. Download PDF

Info

Publication number
ES2322882B1
ES2322882B1 ES200602720A ES200602720A ES2322882B1 ES 2322882 B1 ES2322882 B1 ES 2322882B1 ES 200602720 A ES200602720 A ES 200602720A ES 200602720 A ES200602720 A ES 200602720A ES 2322882 B1 ES2322882 B1 ES 2322882B1
Authority
ES
Spain
Prior art keywords
exocitosis
neuronal
inhibiting peptides
peptides
inhibiting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES200602720A
Other languages
English (en)
Other versions
ES2322882A1 (es
Inventor
Serraima Cristina Carreno
Obiols Berta Ponsati
Den Nest Wim Van
Carneado Jimena Fernandez
Montiel Antonio Ferrer
Puche Joan Cebrian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BCN Peptides SA
Original Assignee
Lipotec SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lipotec SA filed Critical Lipotec SA
Priority to ES200602720A priority Critical patent/ES2322882B1/es
Priority to ARP070104688A priority patent/AR063528A1/es
Priority to EP07823010.9A priority patent/EP2123673B1/en
Priority to ZA200903236A priority patent/ZA200903236B/xx
Priority to DK07823010.9T priority patent/DK2123673T3/en
Priority to RS20170242A priority patent/RS55755B1/sr
Priority to RU2009114804/04A priority patent/RU2461568C2/ru
Priority to CL200703054A priority patent/CL2007003054A1/es
Priority to ES07823010.9T priority patent/ES2638286T3/es
Priority to HUE07823010A priority patent/HUE031340T2/en
Priority to CN200780043641.3A priority patent/CN101541831B/zh
Priority to SI200731897A priority patent/SI2123673T1/sl
Priority to HRP20170378TT priority patent/HRP20170378T1/hr
Priority to HK09111102.3A priority patent/HK1132999B/xx
Priority to MX2009004424A priority patent/MX2009004424A/es
Priority to US12/447,136 priority patent/US9464129B2/en
Priority to AU2007310796A priority patent/AU2007310796B2/en
Priority to BRPI0717376A priority patent/BRPI0717376B8/pt
Priority to JP2009533889A priority patent/JP5647413B2/ja
Priority to PL07823010T priority patent/PL2123673T3/pl
Priority to NZ576373A priority patent/NZ576373A/en
Priority to KR1020097009786A priority patent/KR101606448B1/ko
Priority to LTEP07823010.9T priority patent/LT2123673T/lt
Priority to PT78230109T priority patent/PT2123673T/pt
Priority to PCT/ES2007/000603 priority patent/WO2008049945A1/es
Priority to CA2666516A priority patent/CA2666516C/en
Priority to TW096139868A priority patent/TWI439291B/zh
Priority to IL198191A priority patent/IL198191A/en
Publication of ES2322882A1 publication Critical patent/ES2322882A1/es
Application granted granted Critical
Publication of ES2322882B1 publication Critical patent/ES2322882B1/es
Priority to CY20171100275T priority patent/CY1118690T1/el
Anticipated expiration legal-status Critical
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/14—Liposomes; Vesicles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
ES200602720A 2006-10-25 2006-10-25 Peptidos inhibidores de la exocitosis neuronal. Active ES2322882B1 (es)

Priority Applications (29)

Application Number Priority Date Filing Date Title
ES200602720A ES2322882B1 (es) 2006-10-25 2006-10-25 Peptidos inhibidores de la exocitosis neuronal.
ARP070104688A AR063528A1 (es) 2006-10-25 2007-10-23 Peptidos inhibidores de la exocitosis neuronal
AU2007310796A AU2007310796B2 (en) 2006-10-25 2007-10-24 Neuronal exocytosis inhibiting peptides
DK07823010.9T DK2123673T3 (en) 2006-10-25 2007-10-24 Peptides that inhibit neuronal exocytosis.
RS20170242A RS55755B1 (sr) 2006-10-25 2007-10-24 Peptidi koji inhibiraju egzocitozu iz neurona
RU2009114804/04A RU2461568C2 (ru) 2006-10-25 2007-10-24 Пептиды, ингибирующие нейронный экзоцитоз
CL200703054A CL2007003054A1 (es) 2006-10-25 2007-10-24 Peptido de 3 a 40 aminoacidos capaces de regular la exocitosis neuronal; procedimiento de obtencion de dicho peptido; composicion cosmetica y farmaceutica que comprende dicho peptido; uso de dicho peptido para tratar condiciones que requieran regular
ES07823010.9T ES2638286T3 (es) 2006-10-25 2007-10-24 Péptidos inhibidores de la exocitosis neuronal
HUE07823010A HUE031340T2 (en) 2006-10-25 2007-10-24 Neuronal Exocytosis Peptides
JP2009533889A JP5647413B2 (ja) 2006-10-25 2007-10-24 ニューロンエキソサイトーシス抑制ペプチド
SI200731897A SI2123673T1 (sl) 2006-10-25 2007-10-24 Eksocitoza nevronov inhibirajoči peptidi
HRP20170378TT HRP20170378T1 (hr) 2006-10-25 2007-10-24 Peptidi koji inhibiraju egzocitozu iz neurona
HK09111102.3A HK1132999B (en) 2006-10-25 2007-10-24 Neuronal exocytosis inhibiting peptides
MX2009004424A MX2009004424A (es) 2006-10-25 2007-10-24 Peptidos inhibidores de la exocitosis neuronal.
EP07823010.9A EP2123673B1 (en) 2006-10-25 2007-10-24 Neuronal exocytosis inhibiting peptides
BRPI0717376A BRPI0717376B8 (pt) 2006-10-25 2007-10-24 peptídeos inibidores da exocitose neuronal, processo para a obtenção destes, sua composição cosmética ou farmacêutica e usos destes
PL07823010T PL2123673T3 (pl) 2006-10-25 2007-10-24 Peptydy inhibujące egzocytozę neuronalną
CN200780043641.3A CN101541831B (zh) 2006-10-25 2007-10-24 神经元胞吐抑制性肽类
ZA200903236A ZA200903236B (en) 2006-10-25 2007-10-24 Neuronal exocytosis inhibiting peptides
NZ576373A NZ576373A (en) 2006-10-25 2007-10-24 Neuronal exocytosis inhibiting peptides
KR1020097009786A KR101606448B1 (ko) 2006-10-25 2007-10-24 뉴런성 세포외방출 저해 펩티드
LTEP07823010.9T LT2123673T (lt) 2006-10-25 2007-10-24 Neuronų egzocitozę slopinantys peptidai
PT78230109T PT2123673T (pt) 2006-10-25 2007-10-24 Péptidos inibidores da exocitose neuronal
PCT/ES2007/000603 WO2008049945A1 (es) 2006-10-25 2007-10-24 Péptidos inhibidores de la exocitosis neuronal
CA2666516A CA2666516C (en) 2006-10-25 2007-10-24 Neuronal exocytosis inhibiting peptides
TW096139868A TWI439291B (zh) 2006-10-25 2007-10-24 神經元胞吐抑制性肽類
US12/447,136 US9464129B2 (en) 2006-10-25 2007-10-24 Neuronal exocytosis inhibiting peptides
IL198191A IL198191A (en) 2006-10-25 2009-04-19 Exocytosis inhibitor peptides in neurons
CY20171100275T CY1118690T1 (el) 2006-10-25 2017-03-02 Πεπτιδια αναστολης εξωκυτταρωσης νευρωνων

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200602720A ES2322882B1 (es) 2006-10-25 2006-10-25 Peptidos inhibidores de la exocitosis neuronal.

Publications (2)

Publication Number Publication Date
ES2322882A1 ES2322882A1 (es) 2009-06-30
ES2322882B1 true ES2322882B1 (es) 2010-04-22

Family

ID=39324166

Family Applications (2)

Application Number Title Priority Date Filing Date
ES200602720A Active ES2322882B1 (es) 2006-10-25 2006-10-25 Peptidos inhibidores de la exocitosis neuronal.
ES07823010.9T Active ES2638286T3 (es) 2006-10-25 2007-10-24 Péptidos inhibidores de la exocitosis neuronal

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES07823010.9T Active ES2638286T3 (es) 2006-10-25 2007-10-24 Péptidos inhibidores de la exocitosis neuronal

Country Status (27)

Country Link
US (1) US9464129B2 (es)
EP (1) EP2123673B1 (es)
JP (1) JP5647413B2 (es)
KR (1) KR101606448B1 (es)
CN (1) CN101541831B (es)
AR (1) AR063528A1 (es)
AU (1) AU2007310796B2 (es)
BR (1) BRPI0717376B8 (es)
CA (1) CA2666516C (es)
CL (1) CL2007003054A1 (es)
CY (1) CY1118690T1 (es)
DK (1) DK2123673T3 (es)
ES (2) ES2322882B1 (es)
HR (1) HRP20170378T1 (es)
HU (1) HUE031340T2 (es)
IL (1) IL198191A (es)
LT (1) LT2123673T (es)
MX (1) MX2009004424A (es)
NZ (1) NZ576373A (es)
PL (1) PL2123673T3 (es)
PT (1) PT2123673T (es)
RS (1) RS55755B1 (es)
RU (1) RU2461568C2 (es)
SI (1) SI2123673T1 (es)
TW (1) TWI439291B (es)
WO (1) WO2008049945A1 (es)
ZA (1) ZA200903236B (es)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5019016A (en) 1990-04-10 1991-05-28 Gkn Automotive Inc. Anti-shudder tripod constant velocity universal joint
ES2356883B1 (es) * 2008-07-24 2012-02-22 Bcn Peptides, S.A. Composición para el tratamiento del dolor y/o la inflamación.
US20110305735A1 (en) 2010-06-09 2011-12-15 Lipotec, S.A. Skin antiaging treatment
FR2961510A1 (fr) * 2010-06-17 2011-12-23 Oreal Utilisation comme agent de traitement de la transpiration humaine ; nouveaux derives d'acide amine ; compositions les contenant
ES2385683B1 (es) * 2010-10-18 2013-10-07 Bcn Peptides, S.A. Composiciones para el tratamiento del dolor y/o la inflamación.
US20130287714A1 (en) * 2010-11-12 2013-10-31 Sven Gohla Cosmetic and/or dermatological preparations containing snow algae extract
WO2013070808A1 (en) * 2011-11-07 2013-05-16 Feng Tian Peptide-based compounds as inhibitors of neurotransmitter secretion
ES2424294B1 (es) 2012-03-22 2014-07-21 Lipotec, S.A. Exopolisacárido para el tratamiento y/o cuidado de la piel, mucosas, cabello y/o uñas
EP2649983A1 (en) 2012-04-13 2013-10-16 Lipotec, S.A. Compounds which inhibit neuronal exocytosis (II)
WO2013156064A1 (en) 2012-04-17 2013-10-24 Activen Anti-wrinkles cosmetic composition comprising a mu-conopeptide
EP2649985A1 (en) 2012-04-13 2013-10-16 Lipotec, S.A. Compounds which inhibit neuronal exocytosis (III)
EP2649984A1 (en) * 2012-04-13 2013-10-16 Lipotec, S.A. Compounds which inhibit neuronal exocytosis
US10149812B2 (en) 2012-04-13 2018-12-11 Activen Cosmetic composition comprising a muconopeptide
ES2660901T3 (es) * 2012-04-13 2018-03-26 Lubrizol Advanced Materials, Inc. Compuestos que inhiben la exocitosis neuronal (II)
US10450343B2 (en) 2013-03-21 2019-10-22 Sanofi-Aventis Deutschland Gmbh Synthesis of cyclic imide containing peptide products
HUE034308T2 (en) 2013-03-21 2018-02-28 Sanofi Aventis Deutschland Preparation of hydantoin-containing peptide products
US20160250298A1 (en) 2013-11-01 2016-09-01 Spherium Biomed S.L. Inclusion bodies for transdermal delivery of therapeutic and cosmetic agents
CN103641888B (zh) * 2013-12-03 2015-08-12 广州健坤生物科技有限公司 一种多功能新型小肽、包含该肽的组合物及其应用
CN103637925B (zh) * 2013-12-03 2015-09-30 广州健坤生物科技有限公司 γ-氨基丁酸(GABA)和一种小肽在化妆品中的联合应用
CN103694316B (zh) * 2013-12-31 2015-09-09 杭州华津药业股份有限公司 一种阿基瑞林的制备方法
RU2551276C1 (ru) * 2014-02-03 2015-05-20 Закрытое Акционерное Общество "Фарм-Синтез" Способ получения диацетата трипептида
ES2642916T3 (es) * 2014-06-06 2017-11-20 Galit KLEINER-FISMAN Toxina botulínica para su uso en el tratamiento de la paratonia
CA2965525A1 (en) 2014-10-31 2016-05-06 Lubrizol Advanced Materials, Inc. Thermoplastic polyurethane film for delivery of active agents to skin surfaces
KR101747411B1 (ko) * 2015-04-13 2017-06-14 주식회사 엘지생활건강 신경전달물질을 조절하는 펩타이드의 신경세포 전달용 용해성 미세바늘
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
EP3371238A1 (en) 2015-11-05 2018-09-12 Lubrizol Advanced Materials, Inc. Thermoformable dual network hydrogel compositions
RU2633691C2 (ru) * 2015-12-17 2017-10-16 Федеральное государственное автономное образовательное учреждение высшего образования "Балтийский федеральный университет имени Иммануила Канта" (БФУ им. И. Канта) Способ генетического контроля экзоцитоза на основе генетических конструкций для трансфекции клеток астроглии
KR101895906B1 (ko) * 2016-07-07 2018-10-04 주식회사 한국화장품제조 펩타이드 리포좀을 포함하는 스틱형 화장료 조성물
KR102607079B1 (ko) * 2016-09-09 2023-11-28 주식회사 엘지생활건강 신경세포 투과성이 향상된 신경전달물질 조절 펩타이드
JP7227903B2 (ja) * 2016-11-30 2023-02-22 ルブリゾル アドバンスド マテリアルズ， インコーポレイテッド 皮膚、毛髪、爪および／もしくは粘膜の処置ならびに／またはケアに有用な化合物
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
WO2019004758A2 (ko) * 2017-06-28 2019-01-03 주식회사 엘지생활건강 피부투과 촉진용 펩타이드가 결합된 융합 단백질을 포함하는 피부개선용 화장료 조성물
AU2019228281B2 (en) 2018-02-27 2024-06-13 Lipotrue, S.L. Peptides and compositions for use in cosmetics and medicine
ES3060502T3 (en) * 2018-06-13 2026-03-26 Acraf Peptides having inhibitory activity on neuronal exocytosis
CN109021071B (zh) * 2018-08-21 2020-08-04 山西锦波生物医药股份有限公司 肽及其制备方法和用途
ES3032335T3 (en) * 2019-12-04 2025-07-17 Lipotrue S L Peptides and compositions for use in cosmetics and medicine
WO2022162312A1 (fr) * 2021-01-27 2022-08-04 Fabien Schweighoffer Peptides et leurs utilisations
CN113512092A (zh) * 2021-06-28 2021-10-19 陕西未来多肽生物科技有限公司 多肽纳米杂化物及其用途
CN113402586A (zh) * 2021-06-28 2021-09-17 陕西未来多肽生物科技有限公司 一种多肽及其应用
CN114933634B (zh) * 2021-11-18 2024-08-09 陕西未来多肽生物科技有限公司 一种乙酰基十六肽的合成方法
CN113929749B (zh) * 2021-11-18 2024-08-09 陕西未来多肽生物科技有限公司 一种十六肽化合物及其制备方法
EP4230638A1 (en) 2022-02-16 2023-08-23 Lipotrue, S.L. Peptides and compositions for use in cosmetics
WO2023155881A1 (en) * 2022-02-18 2023-08-24 Tsinghua University Methods for regulating secretion via migrasomes
EP4501944A4 (en) 2022-03-28 2025-10-08 Shenzhen Winkey Tech Co Ltd POLYPEPTIDE AND COSMETIC COMPOSITION OR PHARMACEUTICAL COMPOSITION AND THEIR USE
WO2024011300A1 (en) * 2022-07-13 2024-01-18 L'oreal Modified peptides, composition, method for inhibiting contraction of muscle cells, method for improving the skin and use of a modified peptide
CN118063547A (zh) * 2024-03-01 2024-05-24 深圳市维琪科技股份有限公司 环八肽及其组合物和用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0258111A3 (en) * 1986-08-07 1989-01-25 FIDIA S.p.A. Novel neuronotrophic factor
EP0446931A1 (en) * 1990-03-14 1991-09-18 FIDIA S.p.A. Human ciliary neuronotrophic factor, DNA sequence encoding the factor, and production of the factor by recombinant technology
US6169074B1 (en) 1996-03-18 2001-01-02 The Regents Of The University Of California Peptide inhibitors of neurotransmitter secretion by neuronal cells
ES2160485B1 (es) * 1999-04-23 2002-05-16 Lipotec Sa Peptidos inhibidores de la exocitosis neuronal, composiciones cosmeticas y farmaceuticas que los contienen.
JP4769709B2 (ja) * 2003-05-08 2011-09-07 ディーエスエム アイピー アセッツ ビー．ブイ． 皮膚の構造を改善するために美容上適用するためのトリペプチドおよびその誘導体
ES2293753B1 (es) * 2004-04-28 2009-03-16 Lipotec, S.A. Uso de peptidos xikvav en preparacion de composiciones cosmeticas para mejorar la firmeza de la piel mediante el aumento de la adhesion celular.
ES2362301T3 (es) * 2005-03-03 2011-07-01 Revance Therapeutics, Inc. Composiciones y procedimientos para aplicaciones tópicas y liberación transdérmica de un oligopéptido.
ES2259928B1 (es) * 2005-04-08 2007-11-01 Lipotec, S.A. Composicion cosmetica o dermofarmaceutica que comprende peptidos derivados de encefalinas para reducir y/o eliminar arrugas faciales.
US7807625B2 (en) * 2006-01-18 2010-10-05 Grant Industries, Inc Anti-wrinkle composition

Also Published As

Publication number Publication date
AU2007310796A1 (en) 2008-05-02
BRPI0717376B8 (pt) 2021-05-25
RS55755B1 (sr) 2017-07-31
CN101541831A (zh) 2009-09-23
JP2010507632A (ja) 2010-03-11
HRP20170378T1 (hr) 2017-05-05
CA2666516A1 (en) 2008-05-02
ES2322882A1 (es) 2009-06-30
HK1132999A1 (en) 2010-03-12
CN101541831B (zh) 2015-04-01
CL2007003054A1 (es) 2008-03-24
BRPI0717376A2 (pt) 2013-10-29
KR101606448B1 (ko) 2016-03-25
EP2123673A1 (en) 2009-11-25
HUE031340T2 (en) 2017-07-28
RU2009114804A (ru) 2010-11-27
CA2666516C (en) 2017-06-13
SI2123673T1 (sl) 2017-07-31
AR063528A1 (es) 2009-01-28
EP2123673B1 (en) 2016-12-07
DK2123673T3 (en) 2017-03-20
KR20090090307A (ko) 2009-08-25
ZA200903236B (en) 2010-07-28
PT2123673T (pt) 2017-03-01
TW200833365A (en) 2008-08-16
JP5647413B2 (ja) 2014-12-24
US9464129B2 (en) 2016-10-11
AU2007310796B2 (en) 2013-10-10
PL2123673T3 (pl) 2017-06-30
IL198191A (en) 2016-07-31
NZ576373A (en) 2011-11-25
IL198191A0 (en) 2011-08-01
RU2461568C2 (ru) 2012-09-20
LT2123673T (lt) 2017-03-27
ES2638286T3 (es) 2017-10-19
CY1118690T1 (el) 2017-07-12
WO2008049945A1 (es) 2008-05-02
US20100021510A1 (en) 2010-01-28
TWI439291B (zh) 2014-06-01
MX2009004424A (es) 2009-05-11
EP2123673A4 (en) 2011-01-12
BRPI0717376B1 (pt) 2018-07-24

Similar Documents

Publication Publication Date Title
EP2123673A4 (en) NEURONAL EXOCYTOSIS-INHIBITING PEPTIDES
CR10841A (es) Imidazotriazinas imidazopirimidinas inhibidores de cinasa
DE602007004361D1 (de) Endoskopsystem
DE602007004898D1 (de) Sicherheitsgurtaufroller
FR2909857B1 (fr) Endovalve.
DE602007012976D1 (de) Lenksystem
EP2089308A4 (en) DONOR
EP2027592A4 (en) EVAPORATOR
DK1849352T3 (da) Mejetærsker
EP2007216A4 (en) MERINGUE-WARE SWEET
EP2010561A4 (en) ANTIMICROBIAL PEPTIDES
EP2101804A4 (en) PROANGIOGENIC PEPTIDES
DE602007009224D1 (de) R-cellular-systemen
FI20060178A0 (fi) Pinnoitusmenetelmä
DK2021364T3 (da) Forbedrede antimikrobielle peptider
PT2062053E (pt) Métodos de imunoensaio melhorados
DE602007001118D1 (de) Verbinder
DK2081952T3 (da) Peptider
DE602006010318D1 (de) Tonerverfahren
FR2900262B1 (fr) Portillon de securite
FR2899452B1 (fr) Gondole contreventee
ITCE20060002A1 (it) Patok.
ITCA20060014A1 (it) Raviolo di pompia o arrabiorheddu de pompia
ITCA20060010A1 (it) Spiedatore per anguille o capitoni.
UA13797S (uk) Сірник

Legal Events

Date Code Title Description
EC2A Search report published

Date of ref document: 20090630

Kind code of ref document: A1

FG2A Definitive protection

Ref document number: 2322882B1

Country of ref document: ES

PC2A Transfer of patent

Owner name: BCN PEPTIDES, S.A.

Effective date: 20120905