ES2324168T3 - Procedimiento de preparacion de una disolucion de alfa-1-antitripsina. - Google Patents

Procedimiento de preparacion de una disolucion de alfa-1-antitripsina. Download PDF

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Publication number
ES2324168T3
ES2324168T3 ES04764046T ES04764046T ES2324168T3 ES 2324168 T3 ES2324168 T3 ES 2324168T3 ES 04764046 T ES04764046 T ES 04764046T ES 04764046 T ES04764046 T ES 04764046T ES 2324168 T3 ES2324168 T3 ES 2324168T3
Authority
ES
Spain
Prior art keywords
a1at
procedure
procedure according
viruses
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES04764046T
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English (en)
Spanish (es)
Inventor
Petra Schulz
Jurgen Romisch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Octapharma AG
Original Assignee
Octapharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Octapharma AG filed Critical Octapharma AG
Application granted granted Critical
Publication of ES2324168T3 publication Critical patent/ES2324168T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/16—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/022—Filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/04—Heat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8125—Alpha-1-antitrypsin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ES04764046T 2003-08-12 2004-08-12 Procedimiento de preparacion de una disolucion de alfa-1-antitripsina. Expired - Lifetime ES2324168T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49409703P 2003-08-12 2003-08-12
US494097P 2003-08-12

Publications (1)

Publication Number Publication Date
ES2324168T3 true ES2324168T3 (es) 2009-07-31

Family

ID=34135316

Family Applications (1)

Application Number Title Priority Date Filing Date
ES04764046T Expired - Lifetime ES2324168T3 (es) 2003-08-12 2004-08-12 Procedimiento de preparacion de una disolucion de alfa-1-antitripsina.

Country Status (22)

Country Link
US (1) US20060194300A1 (de)
EP (1) EP1654284B1 (de)
JP (1) JP4668904B2 (de)
KR (1) KR20060070543A (de)
CN (1) CN1867582B (de)
AT (1) ATE428730T1 (de)
AU (1) AU2004262578B2 (de)
BR (1) BRPI0412835A (de)
CA (1) CA2534900A1 (de)
DE (1) DE602004020632D1 (de)
DK (1) DK1654284T3 (de)
ES (1) ES2324168T3 (de)
IL (1) IL172868A0 (de)
NO (1) NO20060109L (de)
PL (1) PL1654284T3 (de)
PT (1) PT1654284E (de)
RS (1) RS20060077A (de)
RU (1) RU2370500C2 (de)
SI (1) SI1654284T1 (de)
UA (1) UA86775C2 (de)
WO (1) WO2005014648A1 (de)
ZA (1) ZA200601206B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005027821A2 (en) * 2003-09-22 2005-03-31 Kamada Ltd. Large scale preparation of alpha-1 proteinase inhibitor and use thereof
ES2246694B1 (es) 2004-04-29 2007-05-01 Instituto Cientifico Y Tecnologico De Navarra, S.A. Nanoparticulas pegiladas.
ES2246695B1 (es) 2004-04-29 2007-05-01 Instituto Cientifico Y Tecnologico De Navarra, S.A. Composicion estimuladora de la respuesta inmunitaria que comprende nanoparticulas a base de un copolimero de metil vinil eter y anhidrido maleico.
CN100354301C (zh) * 2005-10-13 2007-12-12 南京工业大学 化学合成多肽的新型大规模分离制备技术
CN100562523C (zh) * 2006-07-26 2009-11-25 河北大安制药有限公司 α1-抗胰蛋白酶的制备方法
HUE030205T2 (en) * 2007-11-02 2017-05-29 Grifols Therapeutics Inc A method, composition, and product for providing alpha-1-antitrypsin
CN102127165B (zh) * 2010-01-15 2013-09-04 上海莱士血液制品股份有限公司 一种从血浆组分四沉淀中制备高纯ApoA-I的生产工艺
CN102731642B (zh) * 2011-04-14 2014-01-29 上海莱士血液制品股份有限公司 从人血浆组分四沉淀制备高纯Apoa-I的生产工艺
US9353165B2 (en) * 2012-07-25 2016-05-31 Grifols, S.A. Purification of cell culture derived alpha1 protease inhibitor
AU2013205138B2 (en) 2012-08-09 2015-06-25 Grifols, S.A. Caprylate Viral Deactivation
WO2016207353A1 (en) * 2015-06-26 2016-12-29 Ferring B.V. Methods of purification and/or viral inactivation
CA3012694A1 (en) * 2016-02-03 2017-08-10 Plasma Technologies, Llc Methods for extracting proteins from a blood-based material
MX2020004151A (es) 2017-10-30 2020-08-13 Takeda Pharmaceuticals Co Detergentes compatibles con el medio ambiente para la inactivacion de virus envueltos en lipidos.
CN111991571B (zh) * 2020-08-12 2022-04-05 湖州师范学院 一种柱上低pH病毒灭活的方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS584728A (ja) * 1981-05-01 1983-01-11 メデイカル・リサ−チ・インステイチユ−ト・オブ・サンフランシスコ・コ−ポレ−シヨン α−１−抗トリプシンの精製
US4379087A (en) * 1982-06-17 1983-04-05 Cutter Laboratories, Inc. Method of preparing alpha-1-proteinase inhibitor
US4684723A (en) * 1985-09-11 1987-08-04 Miles Laboratories, Inc. Method of separating proteins from aqueous solutions
US4629567A (en) * 1986-03-07 1986-12-16 Smithkline-Rit Alpha-1-antiprotease purification
EP0288841B1 (de) * 1987-04-27 1992-12-30 Miles Inc. Verfahren zur Herstellung von hochgereinigtem alpha-1-Proteinase-Inhibitor
KR920005689B1 (ko) * 1989-12-21 1992-07-13 국제약품공업주식회사 혈청으로부터 알파-1-안티트립신의 분리 정제 및 혈중 알파-1-안티트립신 양의 검정키트
DE4125625C2 (de) * 1991-08-02 1999-12-02 Octapharma Ag Glarus Verfahren zur Herstellung von virusinaktivierten Immunglobulinlösungen
SE9301582D0 (sv) * 1993-05-07 1993-05-07 Kabi Pharmacia Ab Purification of plasma proteins
DE4407837C1 (de) * 1994-03-09 1995-08-17 Octapharma Ag Verfahren zur Gewinnung von hochreinem, virusinaktiviertem alpha¶1¶-Antitrypsin mittels Anionenaustauscher-Chromatographie
US6284874B1 (en) * 1994-06-17 2001-09-04 Alpha Therapeutic Corporation Process for separating α1-proteinase inhibitor from cohn fraction IV1 and IV4 paste
WO1997009350A1 (en) * 1995-09-07 1997-03-13 Ppl Therapeutics (Scotland) Ltd. Purification of alpha-1 proteinase inhibitor
JP4105249B2 (ja) * 1996-08-09 2008-06-25 財団法人化学及血清療法研究所 α２プラスミンインヒビターの製造方法
AT407114B (de) * 1997-06-10 2000-12-27 Immuno Ag Alpha 1-antitrypsin-präparation sowie verfahren zu deren herstellung

Also Published As

Publication number Publication date
JP2007523883A (ja) 2007-08-23
CN1867582A (zh) 2006-11-22
US20060194300A1 (en) 2006-08-31
UA86775C2 (ru) 2009-05-25
AU2004262578B2 (en) 2010-05-06
EP1654284B1 (de) 2009-04-15
CN1867582B (zh) 2010-06-16
PT1654284E (pt) 2009-07-06
EP1654284A1 (de) 2006-05-10
NO20060109L (no) 2006-02-15
IL172868A0 (en) 2006-06-11
CA2534900A1 (en) 2005-02-17
BRPI0412835A (pt) 2006-09-26
ZA200601206B (en) 2007-05-30
PL1654284T3 (pl) 2009-09-30
DK1654284T3 (da) 2009-07-20
SI1654284T1 (sl) 2009-10-31
DE602004020632D1 (de) 2009-05-28
ATE428730T1 (de) 2009-05-15
RS20060077A (sr) 2008-08-07
JP4668904B2 (ja) 2011-04-13
RU2370500C2 (ru) 2009-10-20
AU2004262578A1 (en) 2005-02-17
RU2006107533A (ru) 2006-07-27
WO2005014648A1 (en) 2005-02-17
KR20060070543A (ko) 2006-06-23

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